An immunohistochemical study of NFE2L2, KEAP1 and 8-hydroxy-2'-deoxyguanosine and the EMT markers SNAI2, ZEB1 and TWIST1 in metastatic melanoma.

abstract：:Aneurysmal subarachnoid hemorrhage (SAH) remains a serious cerebrovascular disease. Even if SAH patients survive the initial insults, delayed cerebral ischemia (DCI) may occur at 4 days or later post-SAH. DCI is characteristics of SAH, and is considered to develop by blood breakdown products and inflammatory reactions...

journal_title：Histology and histopathology

authors： Suzuki H,Kanamaru H,Kawakita F,Asada R,Fujimoto M,Shiba M

更新日期：2020-09-30 00:00:00

abstract：:The ultrastructure of four aldosterone secreting adenomas and of the adjacent zona glomerulosa has been described by the use of stereological techniques. Adenomatous cells (about 2800 microns 3 in volume) invariably displayed a striking abundance of lipid droplets, which occupied about 30% of the cytoplasm. Mitochondr...

journal_title：Histology and histopathology

authors： Belloni AS,Mantero F,Rocco S,Gottardo G,Mazzocchi G,Nussdorfer GG

更新日期：1988-07-01 00:00:00

abstract：:The presence of Cajal-Retzius cells in the adult human prefrontal and visual cortices has been demonstrated with calcium binding protein immunocytochemistry and NADPH-diaphorase histochemistry. These cells expressed parvalbumin, calbindin and calretinin calcium binding proteins and displayed NADPH-diaphorase enzyme ac...

journal_title：Histology and histopathology

authors： Martín R,Gutiérrez A,Peñafiel A,Marín-Padilla M,de la Calle A

更新日期：1999-04-01 00:00:00

abstract：:Histochemical distribution of glycoproteins, carbohydrates and proteins rich in different amino acids were studied using histological and histochemical procedures, in Senegal sole, Solea senegalensis (Kaup, 1858) larvae from hatching until day 15. Glycogen, proteins and glycoproteins were detected in the yolk-sac of t...

journal_title：Histology and histopathology

authors： Sarasquete C,González de Canales ML,Arellano JM,Muñoz-Cueto JA,Ribeiro L,Dinis MT

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Gastric Cardiac Cancer (GCC) has high incidence and poor prognosis requiring early screening of high-risk populations. Minichromosome maintenance (MCM) proteins are used as diagnostic-biomarkers in many cancers but not validated for GCC. We evaluate MCM protein 2 (MCM2), comparing it with the validated marke...

journal_title：Histology and histopathology

authors： Liu M,Li JS,Tian DP,Huang B,Rosqvist S,Su M

更新日期：2013-04-01 00:00:00

abstract：:Thrombospondin-1 (TSP-1) is a matrix protein implicated in mechanisms of wound healing. TSP-1 contains the sequence cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) that has been shown to function primarily as a cell adhesion domain. Our laboratory has isolated a novel receptor specific for the CSVTCG adhesi...

journal_title：Histology and histopathology

authors： Roth JJ,Buckmire MA,Rolandelli RH,Granick MS,Tuszynski GP

更新日期：1998-10-01 00:00:00

abstract：:The influence of He-Ne laser radiation on the formation of new blood vessels in the bone marrow compartment of a regenerating area of the mid-cortical diaphysis of the tibiae of young adult rats was studied. A small hole was surgically made with a dentistry burr in the tibia and the injured area received a daily laser...

journal_title：Histology and histopathology

authors： Garavello I,Baranauskas V,da Cruz-Höfling MA

更新日期：2004-01-01 00:00:00

abstract：:Cell secretion is an important physiological process that ensures smooth metabolic activities, tissue repair and growth and immunological functions in the body. It occurs when the intracellular secretory materials are released to the exterior; these may be in the form of lipids, protein or mucous and may travel throug...

journal_title：Histology and histopathology

authors： Gesase AP,Satoh Y

更新日期：2003-04-01 00:00:00

abstract：:The response of the SON to various forms of stress is well documented. However, the effect of operative stress, which is a common and important clinical event requiring the mediation of vasopressin, has largely escaped attention. The present report describes the ultrastructural changes in the neurons of the caudal (re...

journal_title：Histology and histopathology

authors： Ray PK,Choudhury SR

更新日期：1988-04-01 00:00:00

abstract：:Elevated plasma levels of C-reactive protein (CRP) are associated with increased risk of cardiovascular disease. CRP immunoreactive protein is also detected in the lesions of atherosclerosis. However, it is not known whether the CRP contents of atherosclerotic lesions are associated with the initiation and progression...

journal_title：Histology and histopathology

authors： Yu Q,Li Y,Wang Y,Zhao S,Yang P,Chen Y,Fan J,Liu E

更新日期：2012-04-01 00:00:00

abstract：:Differentiating nonspecific interstitial pneumonia (NSIP) from usual interstitial pneumonia (UIP) is important for the determination of both treatment and prognosis. Using two-dimensional fluorescence difference gel electrophoresis (2D-DIGE), we examined 8 UIPs, 8 NSIPs, and 30 normal lung tissues. Comparisons with co...

journal_title：Histology and histopathology

authors： Ohara I,Aida S,Shimazaki H,Kobayashi H,Tsuda H,Toda T,Nakanishi K,Tamai S

更新日期：2014-03-01 00:00:00

abstract：:Aurora A and Aurora B are serine-threonine kinase proteins which have both been implicated in human carcinogenesis through development of aneuploidy and chromosomal instability. The aim of the study is to assess the correlation of both markers with clinical and pathological parameters in patients with bladder cancer o...

journal_title：Histology and histopathology

authors： Bufo P,Sanguedolce F,Tortorella S,Cormio L,Carrieri G,Pannone G

更新日期：2010-11-01 00:00:00

abstract：:The reactivity of endothelial cells to putative endothelial cell-specific markers varies with species, with vessel size and with the organ studied. To determine their value in studies of fetal rat lung, and whether organ immaturity would also influence reactivity, we studied endothelial cell immunoreactivity to antibo...

journal_title：Histology and histopathology

authors： Han RN,Tanswell AK,Post M

更新日期：1992-10-01 00:00:00

abstract：:Oligodendrocytes are the myelinating cells of the central nervous system. Since many studies of demyelinating diseases focus their research on this cell type, there is growing interest for obtaining reliable markers that can specifically recognize oligodendroglia. Established markers are the myelin-associated neurite ...

journal_title：Histology and histopathology

authors： Salinas Tejedor L,Gudi V,Kucman V,Pul R,Gingele S,Sühs KW,Stangel M,Skripuletz T

更新日期：2015-12-01 00:00:00

abstract：:The view of how astrocytes, a type of glial cells, contribute to the functioning of the central nervous system (CNS) has changed greatly in the last decade. Although glial cells outnumber neurons in the mammalian brain, it was considered for over a century that they played a subservient role to neurons. This view chan...

journal_title：Histology and histopathology

authors： Potokar M,Stenovec M,Kreft M,Gabrijel M,Zorec R

更新日期：2011-02-01 00:00:00

abstract：:PML is a tumour suppressor inactivated in Acute Promyelocytic Leukaemia (APL). PML is the essential component of a subnuclear structure called the PML nuclear body (PML-NB), which is disrupted in APL. By targeting different cellular proteins to this structure, PML can either hamper or potentiate their functions. The P...

journal_title：Histology and histopathology

authors： Salomoni P,Bellodi C

更新日期：2007-08-01 00:00:00

abstract：:In order to reveal modulation of the number of pulmonary neuroendocrine cells (PNEC) in interstitial lung diseases and to clarify significance of cell proliferation activity in occurrence of PNEC, we counted airway PNEC of the patients of idiopathic interstitial pneumonia, secondary interstitial pneumonia and control ...

journal_title：Histology and histopathology

authors： Ito T,Ogura T,Ogawa N,Udaka N,Hayashi H,Inayama Y,Yazawa T,Kitamura H

更新日期：2002-10-01 00:00:00

abstract：:The primary objective of this research project was to study the role of sex steroids in the pathogenesis of cholelithiasis using the Syrian hamster as a model. In addition to the morphological examination of the gallbladder epithelium, we thought it imperative to observe the changes induced in the biliary tract in res...

journal_title：Histology and histopathology

authors： Karkare S,Adamiec-Beyga E,Gilloteaux J

更新日期：1995-07-01 00:00:00

abstract：:Factor H (FH) is the predominant soluble inhibitor of the complement system. With a concentration of 200-800 microg/ml in human and rat plasma it acts as a cofactor for the soluble factor I (FI)-mediated cleavage of the component C3b to iC3b. Furthermore it competes with factor B for binding to C3b and C3(H2O) and pro...

journal_title：Histology and histopathology

authors： Demberg T,Heine I,Götze O,Altermann WW,Seliger B,Schlaf G

更新日期：2006-01-01 00:00:00

abstract：:The distribution of peptidergic nerves in canine mammary tissues was studied by immunohistochemical techniques. In addition, the general and the noradrenergic innervations were demonstrated using protein gene product 9.5 and tyrosine hydroxylase immunoreactivities as markers, respectively. Tissue specimens from the ca...

journal_title：Histology and histopathology

authors： Pinho MS,Gulbenkian S

更新日期：2007-11-01 00:00:00

abstract：:Despite years of research into its pathobiology and continuing clinical trials for novel therapies, the prognosis for patients with glioblastoma (GBM) remains dismal. An important obstacle against treatment efficacy may be a high degree of intra- and inter-tumoral heterogeneity within GBMs, which may be caused by the ...

journal_title：Histology and histopathology

authors： Lee HW,Lee K,Kim DG,Yang H,Nam DH

更新日期：2016-03-01 00:00:00

abstract：:One hundred and eleven pituitary glands of patients (93 males, 18 females; mean age 32 years, 5 months) who died of fully developed AIDS or ARC were examined under light microscopy with the aid of immunohistochemistry. On post mortem (p.m.) examination a wide series of multiorgan alterations was noticed. Microscopical...

journal_title：Histology and histopathology

authors： Mosca L,Costanzi G,Antonacci C,Boldorini R,Carboni N,Cristina S,Liverani C,Parravicini C,Pirolo A,Vago L

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Gelatinases include matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9). The abnormal expressions of gelatinases are implicated in the pathogenesis of extracellular matrix (ECM) accumulation. Apolipo-protein E (apoE) is an important plasma protein in cholesterol homeostasis and plays a ...

journal_title：Histology and histopathology

authors： Zhou TB,Qin YH,Lei FY,Su LN,Zhao YJ,Huang WF

更新日期：2012-02-01 00:00:00

abstract：:The corneas of nine pipefish, Corythoichthyes paxtoni (Syngnathidae, Teleostei), five freshly fixed and four museum specimens, were examined using light and electron microscopy. In transverse section, the surface of the corneal epithelium is covered by a complex series of ridges or microplicae which extends over the c...

journal_title：Histology and histopathology

authors： Collin HB,Collin SP

更新日期：1995-04-01 00:00:00

abstract：:The effects of cadmium exposure on the protein secretory functions of cultured neonatal rat hepatocytes were analyzed by both two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and electron microscopy. [35S]Methionine-labelled protein secretion was significantly depressed by cadmium exposure in a dose-depend...

journal_title：Histology and histopathology

authors： Hirano T,Ueda H,Kawahara A,Fujimoto S

更新日期：1991-01-01 00:00:00

abstract：:The presence of synaptophysin, a presynaptic Ca2+ binding glycoprotein, has been analyzed in the cochlear nucleus complex of the adult cat using an antisynaptophysin monoclonal antibody. Synaptophysin immunoreactivity was differently distributed between regions of cochlear nuclei. Terminal boutons contacting directly ...

journal_title：Histology and histopathology

authors： Gil-Loyzaga P,Bartolomé MV,Ibáñez A

更新日期：1998-04-01 00:00:00

abstract：:GLI-similar (Glis) 1-3 proteins constitute a subfamily of the Krüppel-like zinc finger transcription factors that are closely related to the Gli family. Glis1-3 play critical roles in the regulation of a number of physiological processes and have been implicated in several pathologies. Mutations in GLIS2 have been lin...

journal_title：Histology and histopathology

authors： Kang HS,ZeRuth G,Lichti-Kaiser K,Vasanth S,Yin Z,Kim YS,Jetten AM

更新日期：2010-11-01 00:00:00

abstract：:Compliance with current regulations for the development of innovative medicines require the testing of candidate therapies in relevant translational animal models prior to human use. This poses a great challenge when the drug is composed of cells, not only because of the living nature of the active ingredient but also...

journal_title：Histology and histopathology

authors： Ramallo M,Carreras-Sánchez I,López-Fernández A,Vélez R,Aguirre M,Feldman S,Vives J

更新日期：2020-09-11 00:00:00

abstract：:Earlier we reported that atherosclerotic lesions of apoE-deficient mice contained cells which stained positively with anti-S-100 antibody and that cells exhibiting the ultrastructural features of dendritic cells were present in the aortic lesions. These observations suggested that dendritic cells might be involved in ...

journal_title：Histology and histopathology

authors： Bobryshev YV,Taksir T,Lord RS,Freeman MW

更新日期：2001-07-01 00:00:00

abstract：:The proto-oncogene, ets-1, is a transcription factor known to control the expression of a number of genes and has been postulated to play a role in cell growth, differentiation and tumour invasion. We examined 137 cases of breast carcinoma by immunohistochemistry and compared the degree of Ets-1 expression among the d...

journal_title：Histology and histopathology

authors： Katayama S,Nakayama T,Ito M,Naito S,Sekine I

更新日期：2005-01-01 00:00:00