Abstract：
:Earlier we reported that atherosclerotic lesions of apoE-deficient mice contained cells which stained positively with anti-S-100 antibody and that cells exhibiting the ultrastructural features of dendritic cells were present in the aortic lesions. These observations suggested that dendritic cells might be involved in mouse atherosclerosis. By employing DEC-205 and MIDC-8 antibodies specific for dendritic cells, the present study has established that dendritic cells indeed accumulate in atherosclerotic lesions of apoE-deficient mice. Finding dendritic cells infiltrating atherosclerotic lesions in apoE-deficient mice offers the possibility of investigating the migratory routes of dendritic cells and their involvement in T-cell activation.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Bobryshev YV,Taksir T,Lord RS,Freeman MWdoi
10.14670/HH-16.801subject
Has Abstractpub_date
2001-07-01 00:00:00pages
801-8issue
3eissn
0213-3911issn
1699-5848journal_volume
16pub_type
杂志文章abstract：:A novel family of evolutionally conserved neuronal guidance cues, including ligands (i.e., Slit, netrin, epherin, and semaphorin) and their corresponding receptors (i.e., Robo, DCC/Unc5, Eph and plexin/ neuropilin), has been identified to play a crucial role in axon pathfinding and branching as well as neuronal cell m...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-25.1181
更新日期：2010-09-01 00:00:00
abstract：:The main objective of this ultrastructural study was to gain a better understanding of the involvement of brain vasculature in clearance of proteins from edematous fluid. For this purpose, both native and modified (cationized, glucosylated, and mannosylated) bovine serum albumin-gold complexes (BSA-G, catBSA-G, glucBS...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-13.647
更新日期：1998-07-01 00:00:00
abstract：:The possibility of resuscitating livers after warm ischaemia has been recently suggested. The aim of the present investigation was to analyse the effects of anoxia on the morphology of hepatic cells, to determine whether these effects are reversible after providing a resuscitation period between warm ischaemia (WI) an...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:Chronic lung allograft dysfunction (CLAD) still remains a major drawback in the outcome following lung transplantation (LTx). New therapeutic strategies are warranted. Growth factors and their receptors like platelet-derived growth factor-receptor (PDGFR) and vascular endothelial growth factor-receptor (VEGFR), may pl...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-18-088
更新日期：2019-07-01 00:00:00
abstract：:Early observations that cultured mesenchymal stem cells (MSCs) could be induced to exhibit certain characteristics of osteocytes and chondrocytes led to the proposal that they could be transplanted for tissue repair through cellular differentiation. Therefore, many subsequent preclinical studies with transplanted MSCs...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-28.1109
更新日期：2013-09-01 00:00:00
abstract：:The low density lipoprotein receptor-related protein (LRP) 1 is a ubiquitously expressed, versatile cell surface transmembrane receptor involved in embryonic development and adult tissue homeostasis. LRP1 binds and endocytoses a broad spectrum of over 40 ligands identified thus far, including lipoproteins, extracellul...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-11-746
更新日期：2016-07-01 00:00:00
abstract：:Testis samples were taken from young (3 months), middle-aged (12 months) and aged (24 months) male rats, processed, stained and examined via a light microscope. There were no prominent abnormal germinal epithelium and interstitial tissue. However, the aging process promoted a significant decrease in the mean amount of...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:Telocytes (TCs) represent a new distinct type of interstitial cells found in many organs, including lungs. TCs are mainly defined by a small cellular body from which arise very long (hundreds of micrometers) extensions named telopodes. During the last years, TCs were characterized in respect with their microRNA profil...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-11-807
更新日期：2016-12-01 00:00:00
abstract：:In the present work a morphopathological study is carried out of the glomerular filtration barrier in 20 Large-White pigs weighing 20 kg, subjected to experimental intravenous inoculations of endotoxin from Salmonella enteritidis. The study is completed with the determination of protein plasmatic levels, through urine...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：:A number of tumor suppressor and tumor-related genes exhibit promoter hypermethylation with resulting gene silencing in human cancers. In addition, several gene promoters have also been shown to become hypermethylated in non-neoplastic cells during aging. To assess the physiological consequence and clinical significan...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-19.221
更新日期：2004-01-01 00:00:00
abstract：:Cerebral cavernous malformations (CCMs) are described as vascular lesions consisting of endothelial-lined dilated vessels embedded in a connective tissue sheath without intervening parenchyma between them. Their anatomical connections with the normal blood vessels are still enigmatic and the fine three-dimensional (3-...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-29.1071
更新日期：2014-08-01 00:00:00
abstract：UNLABELLED:The aim of this work was to evaluate the effect of magnesium sulphate (MgSO4) administration on blood-brain barrier (BBB) permeabilization after cerebral hypoxia-ischemia (HI) induced by partial occlusion of the umbilical cord of premature fetal lambs. We also characterized BBB dysfunction in terms of the le...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-24.1129
更新日期：2009-09-01 00:00:00
abstract：:To understand the role of microtubules and microfilaments in regulating endothelial monolayer integrity and repair, and since microtubules and microfilaments show some co-alignment in endothelial cells, we tested the hypothesis that microtubules organize microfilament distribution. Disruption of microtubules with colc...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-20.455
更新日期：2005-04-01 00:00:00
abstract：:Identification of robust diagnostic and therapeutic target molecules for human malignancy is still an important issue. If we identify novel proteins which play a stem-line role for cellular transformation or aggravation of malignancy, it could give us a clue to diagnose a tumor in an earlier stage and to develop more ...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-20.999
更新日期：2005-07-01 00:00:00
abstract：:Experimental Doxorubicin-exposure in utero is correlated with foetal oesophageal atresia, tracheo-oesophageal fistula, axial alterations. While gastrointestinal and respiratory defects have been largely investigated, only sporadic data have been published to date on notochordal and vertebral defects. The aim of this w...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-17.31
更新日期：2002-01-01 00:00:00
abstract：:Mitochondrial transcription factor A (mtTFA) plays a crucial role in both the transcription and maintenance of mitochondrial DNA. A high expression of mtTFA has been demonstrated in several solid tumors, and is closely associated with cancer cell survival/apoptosis and growth. However, its expression pattern in pancre...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-30.193
更新日期：2015-02-01 00:00:00
abstract：:A rat IgG2a monoclonal antibody against a stage-specific fetal glycoprotein with a molecular mass of 68 kDa (FGP68) was produced and applied to paraffin sections. This monoclonal antibody was used to compare the expression of FGP68 with that of both alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) in 75 hepa...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-19.701
更新日期：2004-07-01 00:00:00
abstract：:A comparative histochemical and morphometric study in two groups of homologous muscles from different tetrapods (rat, pigeon, lizard and frog) was performed. On the basis of their fiber diameters and oxidative enzyme activities, an initial correlation between fiber types of all animals is observed, although in the liz...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:The vacuolar-type H(+)-ATPases (V-ATPases) are a family of multi-subunit ATP-dependent proton pumps involved in diverse cellular processes, including acid/base homeostasis, receptor-mediated endocytosis, processing of proteins and signaling molecules, targeting of lysosomal enzymes, and activation of various degradati...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-25.1611
更新日期：2010-12-01 00:00:00
abstract：:Renal oncocytosis is a recently established disease entity characterized by numerous oncocytic tumors and diffuse involvement of oncocytic changes in renal parenchymal epithelia. In this article, we review this disease with a focus on its clinical and pathobiological aspects. Clinically, renal oncocytosis may occur in...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-27.1407
更新日期：2012-11-01 00:00:00
abstract：:The nerve fiber distribution in the epidermis of the hairless rat skin was studied light microscopically by means of zinc iodide-osmium tetroxide staining. Two different morphological types of free nerve fiber endings could be detected: clusters of relatively thick nerve fibers stretched up through the spinous layer u...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-15.493
更新日期：2000-04-01 00:00:00
abstract：:Platelet-collagen interaction is a complex event that involves ligand-receptor interaction. There are many adhesive non-integrin receptors for platelets to interact with various types of collagens. These non-integrin receptors also serve as signal transducers both from the outside of platelets to the inside and possib...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-14.579
更新日期：1999-04-01 00:00:00
abstract：:Ebulin f is a ribosome-inactivating protein (RIP) present in green fruits of the dwarf elder (Sambucus ebulus L). Since dwarf elder fruits are used for food and as a medicine, we assessed the study of toxicological effects and safety of ebulin f in elderly mice, comparing these results with those reported in young ani...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-11-992
更新日期：2018-09-01 00:00:00
abstract：:This study evidences the presence of primordial germ cells, in tissue squash preparations and sections from hematological malignancies. Primordial germ cells were identified by their morphology, the intense PAS, PAS-D reaction and presence of calcium-activated neutral proteinase. Primordial germ cells gave rise to nuc...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:In order to reveal modulation of the number of pulmonary neuroendocrine cells (PNEC) in interstitial lung diseases and to clarify significance of cell proliferation activity in occurrence of PNEC, we counted airway PNEC of the patients of idiopathic interstitial pneumonia, secondary interstitial pneumonia and control ...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-17.1121
更新日期：2002-10-01 00:00:00
abstract：:Strain injuries of tendons are the most common orthopedic injuries in athletic subjects, be they equine or human. When the tendon is suddenly damaged, an acute inflammatory phase occurs whereas its repetitive overloading may cause chronic injuries. Currently the criteria used for grading injuries are general and subje...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-11-601
更新日期：2015-08-01 00:00:00
abstract：:Introduction. Gastrointestinal stromal tumors (GISTs) are characterized at the molecular level by c-kit or PDGFRA oncogene mutations. Although GISTs raised major interest in past decades, population-based studies are still rare. Materials and Methods. All GISTs diagnosed in Southern Switzerland (1999-2005) were identi...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-23.1379
更新日期：2008-11-01 00:00:00
abstract：:The study was carried out on the distribution of neurons and fibres which contain the Corticotropin releasing factor-like (CRF) immunoreactivity in the encephalon of two species of teleosts, Gambusia affinis and Salmo trutta. The peroxidase-antiperoxidase (PAP) immunocytochemical technique was employed. The present st...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：BACKGROUND:Gelatinases include matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9). The abnormal expressions of gelatinases are implicated in the pathogenesis of extracellular matrix (ECM) accumulation. Apolipo-protein E (apoE) is an important plasma protein in cholesterol homeostasis and plays a ...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-27.249
更新日期：2012-02-01 00:00:00
abstract：:The aim of this study was to demonstrate the morphology and matrix synthesis of embryonic rat liver cells (day 18 of gestation) in organoid cultures (high density cultures) with electron microscopic and immunomorphological techniques. For this purpose the cells of embryonic rat livers were isolated enzymatically and g...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
