New insights into the cytoplasmic function of PML.

abstract：:Fluoxetine shows controversial lung effects as it prevents pulmonary hypertension in adult rats but exposure during gestation causes pulmonary hypertension in neonatal rats. In the present study, we tested the null hypothesis that the antidepressant drug fluoxetine does not modify the development of bronchopulmonary d...

journal_title：Histology and histopathology

authors： Porzionato A,Zaramella P,Macchi V,Grisafi D,Salmaso R,Baraldi M,Fornaro E,Tassone E,Masola V,Onisto M,Chiandetti L,De Caro R

更新日期：2012-12-01 00:00:00

abstract：:The resistance to airflow that develops in most obstructive processes takes place in the small airways. The aim of the present paper is to describe bronchial hysteresis morphometrically in a respiratory cycle model. As a working hypothesis, it is proposed that the changes that take place in the respiratory tract durin...

journal_title：Histology and histopathology

authors： Escolar JD,Escolar MA,Guzmán J,Roqués M

更新日期：2003-01-01 00:00:00

abstract：:In recent years, the different mechanisms of epithelial cell loss which occur in mammalian and avian small intestine have been re-investigated. Information is now available for a variety of mammalian types and mechanisms can be divided into two major classes: [i] those preserving epithelial integrity by maintaining in...

journal_title：Histology and histopathology

authors： Mayhew TM,Myklebust R,Whybrow A,Jenkins R

更新日期：1999-01-01 00:00:00

abstract：:Despite years of research into its pathobiology and continuing clinical trials for novel therapies, the prognosis for patients with glioblastoma (GBM) remains dismal. An important obstacle against treatment efficacy may be a high degree of intra- and inter-tumoral heterogeneity within GBMs, which may be caused by the ...

journal_title：Histology and histopathology

authors： Lee HW,Lee K,Kim DG,Yang H,Nam DH

更新日期：2016-03-01 00:00:00

abstract：:Programmed death-ligand 1 (PD-L1) is an inhibitory transmembrane protein that can prevent autoimmune response. Upregulated PD-L1 serves as a predictive biomarker for patients who may respond well to immune checkpoint therapies. However, variable associations of PD-L1 level with prognoses have been reported. In this st...

journal_title：Histology and histopathology

authors： Su BC,Ting CH,Lee KY,Wu SM,Feng PH,Chan YF,Chen JY

更新日期：2020-10-28 00:00:00

abstract：:Emperipolesis has recently been described as a constant feature of "biphasic squamoid" papillary renal cell carcinoma (BPRCC). We also noticed this in some high-grade (HG) RCC, which promoted the present study to estimate the incidence of emperipolesis in RCCs and to describe them in further detail. 14 cases of HGRCC ...

journal_title：Histology and histopathology

authors： Rotterova P,Martinek P,Alaghehbandan R,Prochazkova K,Damjanov I,Rogala J,Suster S,Perez-Montiel D,Alvarado-Cabrero I,Sperga M,Svajdler M,Michalova K,Pivovarcikova K,Daum O,Hora M,Dusek M,Ondic O,Stehlikova A,Michal M

更新日期：2018-03-01 00:00:00

abstract：:A number of tumor suppressor and tumor-related genes exhibit promoter hypermethylation with resulting gene silencing in human cancers. In addition, several gene promoters have also been shown to become hypermethylated in non-neoplastic cells during aging. To assess the physiological consequence and clinical significan...

journal_title：Histology and histopathology

authors： Tamura G

更新日期：2004-01-01 00:00:00

abstract：:In order to analyze the incidence and prevalence of Human Papillomavirus (HPV) in penile carcinoma, we studied 49 patients with penile carcinoma. Formalin-fixed, paraffin-embedded tissue samples were collected from 64 samples of penile carcinoma from the Hospital General Universitario (Albacete, Spain). Cases were his...

journal_title：Histology and histopathology

authors： Pascual A,Pariente M,Godínez JM,Sánchez-Prieto R,Atienzar M,Segura M,Poblet E

更新日期：2007-02-01 00:00:00

abstract：:Orexins A and B are two hypothalamic peptides, involved in the central regulation of feeding, which act through two receptor subtypes, named OX1R and OX2R. OX1R is selective for orexin-A, and OX2R binds both orexins. We have investigated the effects of three subcutaneous injections of 10 nmol/kg body weight of orexins...

journal_title：Histology and histopathology

authors： Malendowicz LK,Jedrzejczak N,Belloni AS,Trejter M,Hochól A,Nussdorfer GG

更新日期：2001-07-01 00:00:00

abstract：:Pneumadin (PNM) is a biologically active decapeptide, which has previously been found to enhanced rat adrenal growth; the mechanism is indirect and probably involves the stimulation of both arginine-vasopressin (AVP) and ACTH release. The effects of 2- and 6-day PNM administration on the atrophic adrenal cortices of r...

journal_title：Histology and histopathology

authors： Markowska A,Andreis PG,Miskowiak B,Nussdorfer GG,Malendowicz LK

更新日期：1997-07-01 00:00:00

abstract：:Anthracyclines are one of the most effective anticancer drugs ever developed, but their clinical use has been hampered by the risk of severe cardiotoxicity. In this study, we investigated whether rabbits exposed to a different cumulative dose of anthracycline suffer from immunohistochemically detectable vascular toxic...

journal_title：Histology and histopathology

authors： Nachtigal P,Sterba M,Popelová O,Večeřová L,Kudláčková Z,Jirkovský E,Geršl V

更新日期：2011-05-01 00:00:00

abstract：:Neurotrophins are substances that have been shown to be important in growth and remodelling phases in different types of tissue. There is no information concerning the possible occurrences of neurotrophins and their receptors in tendons. In this study, sections of both chronic painful (tendinosis) and pain-free (non-t...

journal_title：Histology and histopathology

authors： Bagge J,Lorentzon R,Alfredson H,Forsgren S

更新日期：2009-07-01 00:00:00

abstract：:Chorioamnionitis and preeclampsia account for the majority of preterm births worldwide. Thus far, adequate methods for early detection or prevention of these diseases are lacking. In preeclampsia, accelerated villous maturation is believed to compensate placental insufficiency. However, little is known about the effec...

journal_title：Histology and histopathology

authors： Vangrieken P,Vanterpool SF,van Schooten FJ,Al-Nasiry S,Andriessen P,Degreef E,Alfer J,Kramer BW,von Rango U

更新日期：2020-08-01 00:00:00

abstract：:Pulmonary fibrosis is a common response to various injuries to the lung. The resolution of a fibroproliferative response after lung injury is key to survival. Although there are various initiating factors or causes, the terminal stages are characterized by proliferation and progressive accumulation of connective tissu...

journal_title：Histology and histopathology

authors： Kuwano K,Hagimoto N,Nakanishi Y

更新日期：2004-07-01 00:00:00

abstract：:Platelet-collagen interaction is a complex event that involves ligand-receptor interaction. There are many adhesive non-integrin receptors for platelets to interact with various types of collagens. These non-integrin receptors also serve as signal transducers both from the outside of platelets to the inside and possib...

journal_title：Histology and histopathology

authors： Chiang TM

更新日期：1999-04-01 00:00:00

abstract：:An immunohistochemical study of matrix metalloproteinases (MMP-2 and MMP-9) or gelatinase (gelatinase A and gelatinase B) was performed on the seminal vesicles and ventral prostate of the Libyan jird (Meriones libycus) collected in the Beni-Abbes area during breeding period (spring and early summer), during resting ph...

journal_title：Histology and histopathology

authors： Belhocine M,Gernigon-Spychalowicz T,Jacob MP,Benazzoug Y,Exbrayat JM

更新日期：2010-05-01 00:00:00

abstract：:The effect of prolonged exposure to normobaric hypoxia on the mitochondria of myocard of rats exposed for several weeks to 8 and 7% O2 has been morphometrically evaluated. Twelve male Wistar rats housed in Nalgene cages (2 per cage) with a batch of six cages placed in plexiglass chambers were maintained in air/N2 mixt...

journal_title：Histology and histopathology

authors： Cervós Navarro J,Kunas RC,Sampaolo S,Mansmann U

更新日期：1999-10-01 00:00:00

abstract：:The present study describes the use of a microwave processing protocol for the rapid histopathological and immunohistochemical diagnosis of bovine rabies. Immunohistochemistry has been used for rabies diagnosis in formalin-fixed tissue with satisfactory results, although the time to diagnosis is considerably longer th...

journal_title：Histology and histopathology

authors： Abreu CC,Nakayama PA,Nogueira CI,Mesquita LP,Lopes PF,Varaschin MS,Seixas Jdo N,Ferreira E,Bezerra PS Jr

更新日期：2012-09-01 00:00:00

abstract：:We review the morphofunctional characteristics of CD34+ stromal fibroblastic/fibrocytic cells (CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ SFCs: A) The confusing terms applied to this cell type, often combining the prefix CD34 with numerous names, including fibroblasts, fibrocyt...

journal_title：Histology and histopathology

authors： Díaz-Flores L,Gutiérrez R,García MP,Sáez FJ,Díaz-Flores L Jr,Valladares F,Madrid JF

更新日期：2014-07-01 00:00:00

abstract：:CD24 is known to be an important diagnostic and prognostic marker of several major cancers affecting females. We aimed to determine CD24 expression in normal, hyperplastic, and carcinomatous endometrium and its correlation with estrogen and progesterone receptor expression. A total of 271 cases including 62 normal/atr...

journal_title：Histology and histopathology

authors： Kim KH,Choi JS,Kim JM,Choi YL,Shin YK,Lee HC,Seong IO,Kim BK,Chae SW,Kim SH

更新日期：2009-03-01 00:00:00

abstract：:β-lapachone is a quinone of lapachol extracted from the bark of lapacho tree. Recent findings demonstrated that punched skin wounds of mice healed faster with β-lapachone treatment. The present study investigates the effects of β-lapachone on burn-wound skin of C57BL/6 mice injured by a 100 °C iron stick. Our results ...

journal_title：Histology and histopathology

authors： Fu SC,Chau YP,Lu KS,Kung HN

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Gastric Cardiac Cancer (GCC) has high incidence and poor prognosis requiring early screening of high-risk populations. Minichromosome maintenance (MCM) proteins are used as diagnostic-biomarkers in many cancers but not validated for GCC. We evaluate MCM protein 2 (MCM2), comparing it with the validated marke...

journal_title：Histology and histopathology

authors： Liu M,Li JS,Tian DP,Huang B,Rosqvist S,Su M

更新日期：2013-04-01 00:00:00

abstract：:The presence of Cajal-Retzius cells in the adult human prefrontal and visual cortices has been demonstrated with calcium binding protein immunocytochemistry and NADPH-diaphorase histochemistry. These cells expressed parvalbumin, calbindin and calretinin calcium binding proteins and displayed NADPH-diaphorase enzyme ac...

journal_title：Histology and histopathology

authors： Martín R,Gutiérrez A,Peñafiel A,Marín-Padilla M,de la Calle A

更新日期：1999-04-01 00:00:00

abstract：:Thyroid hormones (TH) stimulate oxidative metabolism in many tissues in the body, but testis is not one of them. Therefore, in this sense, testis is not considered as a target organ for TH. However, recent findings clearly show that TH have significant functions on the testis in general, and Leydig cells in particular...

journal_title：Histology and histopathology

authors： Mendis-Handagama SM,Ariyaratne HB

更新日期：2004-07-01 00:00:00

abstract：:TIMPs in the prostates of male and female gerbils and evaluated the effects of testosterone on the expression of these enzymes. Ventral prostates from male gerbils that were either intact or had been castrated for 7 or 21 days, along with prostates from female gerbils that were either intact or had been treated with t...

journal_title：Histology and histopathology

authors： Rochel-Maia SS,Santos FC,Vilamaior PS,Justulin LA Jr,Felisbino SL,Góes RM,Taboga SR

更新日期：2011-11-01 00:00:00

abstract：:Osteoarthritis (OA) is characterized by cartilage attrition, subchondral bone remodeling, osteophyte formation and synovial inflammation. Perturbed homeostasis caused by inflammation, oxidative stress, mitochondrial dysfunction and proapoptotic/antiapoptotic dysregulation is known to impair chondrocyte survival in joi...

journal_title：Histology and histopathology

authors： Musumeci G,Loreto C,Carnazza ML,Strehin I,Elisseeff J

更新日期：2011-10-01 00:00:00

abstract：:The matrix metalloproteinases (MMPs) are a family of proteolytic zinc-containing enzymes, which are responsible for the breakdown of the extracellular matrix components in pathological and physiological conditions. They are involved in basement membrane disruption, stroma and blood vessel penetration, metastasis and m...

journal_title：Histology and histopathology

authors： Peschos D,Damala C,Stefanou D,Tsanou E,Assimakopoulos D,Vougiouklakis T,Charalabopoulos K,Agnantis NJ

更新日期：2006-06-01 00:00:00

abstract：:A current concern about the biological effects of electromagnetic fields (EMF) is increasing with the wide spread use of X-band microwaves (MW, 8-10 GHz range). Gigahertz transverse electromagnetic (GTEM) field flat transmission lines are currently being used for experimental exposure of biological samples to high fre...

journal_title：Histology and histopathology

authors： Pérez-Bruzón RN,Del Moral A,Pérez-Castejón C,Llorente M,Vera A,Azanza MJ

更新日期：2011-09-01 00:00:00

abstract：:Junctional complexes such as tight junctions, adherens junctions, and desmosomes play crucial roles in the structure and function of epithelial cells. These junctions are involved in increasing cell-cell contact and as well serve as signaling centers regulating multiple functions in epithelial cells. Carcinoma cell li...

journal_title：Histology and histopathology

authors： Kim G,Rajasekaran SA,Thomas G,Rosen EA,Landaw EM,Shintaku P,Lassman C,Said J,Rajasekaran AK

更新日期：2005-01-01 00:00:00

abstract：:A proportion of anaplastic large cell tumours is difficult to classify on sections of routinely processed, paraffin-embedded tissue. Differentiation into large cell lymphoma, carcinoma, melanoma or sarcoma is important in order to assess prognosis and proper treatment. Although the use of immunohistochemistry has been...

journal_title：Histology and histopathology

authors： Henzen-Logmans SC,Mullink H,Vennegoor C,Hilgers J,Oort J,Meijer CJ

更新日期：1987-04-01 00:00:00