The effects of low laser irradiation on angiogenesis in injured rat tibiae.

Abstract:

:The influence of He-Ne laser radiation on the formation of new blood vessels in the bone marrow compartment of a regenerating area of the mid-cortical diaphysis of the tibiae of young adult rats was studied. A small hole was surgically made with a dentistry burr in the tibia and the injured area received a daily laser therapy over 7 or 14 days transcutaneously starting 24 h from surgery. Incident energy density dosages of 31.5 and 94.5 Jcm(-2) were applied during the period of the tibia wound healing investigated. Light microscopic examination of histological sections of the injured area and quantification of the newly-formed blood vessels were undertaken. Low-level energy treatment accelerated the deposition of bone matrix and histological characteristics compatible with an active recovery of the injured tissue. He-Ne laser therapy significantly increased the number of blood vessels after 7 days irradiation at an energy density of 94.5 Jcm(-2), but significantly decreased the number of vessels in the 14-day irradiated tibiae, independent of the dosage. These effects were attributed to laser treatment, since no significant increase in blood vessel number was detected between 8 and 15 non-irradiated control tibiae. Molecular mechanisms involved in low-level laser therapy of angiogenesis in post-traumatic bone regeneration needs further investigation.

journal_name

Histol Histopathol

authors

Garavello I,Baranauskas V,da Cruz-Höfling MA

doi

10.14670/HH-19.43

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

43-8

issue

1

eissn

0213-3911

issn

1699-5848

journal_volume

19

pub_type

杂志文章
  • Paracrine role for TGF-β-induced CTGF and VEGF in mesangial matrix expansion in progressive glomerular disease.

    abstract::Transforming growth factor-β (TGF-β) is a key regulator of extracellular matrix (ECM), and may mediate the development of glomerulosclerosis with accumulation of mesangial matrix. Mesangial cells secrete TGF-β in response to common in vitro fibrogenic stimuli. Yet mesangial immunostaining for active TGF-β1 is frequent...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-27.1131

    authors: Lee HS

    更新日期:2012-09-01 00:00:00

  • Regulation and function of sphingosine kinase 2 in diseases.

    abstract::Sphingosine kinase functions to phosphorylate sphingosine to sphingosine 1-phosphate (S1P) to keep balance in the metabolites of sphingolipids. There are two isoforms of sphingosine kinase, sphingosine kinase 1 (SphK1) and sphingosine kinase 2 (SphK2). Although SphK1 and SphK2 share high sequence similarity, SphK2 has...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-11-939

    authors: Song DD,Zhou JH,Sheng R

    更新日期:2018-05-01 00:00:00

  • Effects of pinealectomy on the ultrastructure of the golden hamster parathyroid gland.

    abstract::Ultrastructural changes of the parathyroid glands of pinealectomized golden hamsters were investigated. The main changes in the parathyroid glands 1 hour and 1 day after pinealectomy compared with the control and sham-operated groups were an increase of the Golgi complexes, cisternae of the granular endoplasmic reticu...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Chen H,Shoumura S,Emura S,Utsumi M,Yamahira T,Isono H

    更新日期:1990-10-01 00:00:00

  • Local extension of HMGB1 in atherosclerotic lesions of human main cerebral and carotid arteries.

    abstract::High mobility group box 1 protein (HMGB1) is a non-histone chromosomal protein which is highly conserved, ubiquitous, and widely distributed. HMGB1 has multiple functions in the nucleus, including the maintenance of nucleosome structure, the regulation of gene transcription, and involvement in DNA recombination. HMBG1...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-29.235

    authors: Umahara T,Uchihara T,Koyama S,Hashimoto T,Akimoto J,Haraoka J,Iwamoto T

    更新日期:2014-02-01 00:00:00

  • Roles of versican in cancer biology--tumorigenesis, progression and metastasis.

    abstract::Versican, a large extracellular matrix proteoglycan accumulates in tumor stroma and plays a key role in both malignant transformation and tumor progression. Increased versican expression has been observed in a wide range of malignant tumors, and has been associated with both cancer relapse and poor patient outcomes in...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-28.701

    authors: Du WW,Yang W,Yee AJ

    更新日期:2013-06-01 00:00:00

  • Morphometric study on the interhemispheric asymmetries in the Wistar rat and the effects of early experience.

    abstract::Sixty male Wistar rats were used for this experiment and assigned at random to the control group or to the stimulation method. Control rats show cerebral asymmetry with right bias at the frontal and occipital lobes. In the case of stimulated rats the differences from the occipital zone increase while those from the fr...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Isasa Chueca JA,Lahoz Gimeno M,Redondo Marco JA

    更新日期:1992-07-01 00:00:00

  • Histology of skeletal muscle reconstructed by means of the implantation of autologous adipose tissue: an experimental study.

    abstract::The purpose of this study was to determine the histological characteristics of a skeletal muscle reconstructed by means of the implantation of autologous adipose tissue following an experimentally-induced volumetric muscle loss. A cylindrical piece in the belly of the rat anterior tibial muscle was removed. In the hol...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-18-163

    authors: Leiva-Cepas F,Jimena I,Ruz-Caracuel I,Luque E,Villalba R,Peña-Amaro J

    更新日期:2020-05-01 00:00:00

  • Circadian and seasonal cortico-medullary variations in pinealocyte nuclear size. A comparative statistical analysis.

    abstract::Circadian and seasonal variations were observed in the karyometric index of pinealocytes in the cortical and medullary regions of the distal pineal body. The study involved 70 Wistar rats over a 24-hour interval (0:6, 10:00, 14:00, 18:00, 22:00, 02:00, 06:00 h) during two natural photoluminous periods, i.e. late summe...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Cimas García C,Martínez Soriano F,Ruiz Torner A

    更新日期:1992-10-01 00:00:00

  • M1- and M2-macrophage polarization in thioacetamide (TAA)-induced rat liver lesions; a possible analysis for hepato-pathology.

    abstract::"Classically activated macrophages (M1)" and "alternatively activated macrophages (M2)", which appear in injured tissues, control either inflammation or remodeling. The mechanism remains unclear. To clarify the M1-/M2-macrophage polarization in acute liver injury, M1- and M2-related factors were analysed in F344 rats ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-29.10.497

    authors: Wijesundera KK,Izawa T,Murakami H,Tennakoon AH,Golbar HM,Kato-Ichikawa C,Tanaka M,Kuwamura M,Yamate J

    更新日期:2014-04-01 00:00:00

  • Immunohistochemical determination of mTOR pathway molecules in ovaries and uterus in rat estrous cycle stages.

    abstract::mTOR is a member of the PI3K/Akt/mTOR signaling pathway that participates in cell growth, proliferation, protein synthesis, transcription, angiogenesis, apoptosis and autophagy. mTOR and MAPK pahways are two important key signal pathways which are related to each other. We investigated the role of mTOR and other signa...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-18-258

    authors: Ekizceli G,Inan S,Oktem G,Onur E,Ozbilgin K

    更新日期:2020-11-01 00:00:00

  • Transforming growth factor-beta1 gene and protein expression associated with atherogenesis of cholesterol-fed rabbits.

    abstract::Transforming growth factor-beta1 (TGF-1beta) has been shown to modulate both cell proliferation and the synthesis of extracellular matrix by vascular cells. This study was aimed to establish the temporal correlation between TGF-beta1 expression, the expression of the extracellular matrix protein fibronectin, and plaqu...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-15.421

    authors: Chen YL,Wu HW,Jiang MJ

    更新日期:2000-04-01 00:00:00

  • Abnormal distribution of CD45 isoforms expressed by CD4+ and CD8+ T cells in rheumatoid arthritis.

    abstract::CD45RO+ T cells are referred to as memory or helper-inducer while CD45RA+ T cells are regarded as naive or suppressor-inducer T cells. The former population predominates in the peripheral blood and even more in the synovial fluid of patients with rheumatoid arthritis, to the expense of the latter population. Within th...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-15.587

    authors: Mamoune A,Durand V,Le Goff P,Pennec YL,Youinou P,Le Corre R

    更新日期:2000-04-01 00:00:00

  • The combined effect of honey and olive oil against methotrexate mediated hepatotoxicity in rats: A biochemical, histological and immunohistological study.

    abstract:BACKGROUND:Honey and olive oil are natural products that have high nutritional values, and therapeutic properties. Cytotoxic drugs, like methotrexate (MTX) are used to treat malignancies in tumour cells; however, these drugs also have serious side effects that could threaten the patient's life. AIM:To evaluate the pot...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-18-126

    authors: Alturkistani HA,Abuzinadah OAH,Kelany AM,Abd El-Aziz GS,Alrafiah AR

    更新日期:2019-12-01 00:00:00

  • Immunophenotypic characterization of primary and secondary lymphoid follicles.

    abstract::The need for an immunophenotypical referential framework relative to lymphoid follicle has led us to apply a panel of monoclonal and polyclonal antibodies, by means of a sensitive immunostaining method. Lymphoid follicle is an immunophenotypically complex structure made up of three lymphoid populations (B, being its b...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: de Luaces CP,Peral JI,García Tejeiro M,Aguirre C

    更新日期:1988-01-01 00:00:00

  • Neutrophil extracellular traps in tissue pathology.

    abstract::Neutrophil extracellular traps (NETs) are innate immune systems against invading pathogens. NETs are characterized as released DNA mixed with cytoplasmic antimicrobial proteins such as myeloperoxidase, proteinase3 and neutrophil elastase. While NETs are thought to have an important role in host defense, recent work ha...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-11-816

    authors: Nakazawa D,Kumar S,Desai J,Anders HJ

    更新日期:2017-03-01 00:00:00

  • Three-dimensional architecture of the connective tissue core and surface structures of the lingual papillae in the rabbit.

    abstract::Three-dimensional characteristics of the epithelial cell layer and connective tissue interface of the tongue were studied using scanning electron microscopy. In this study, the fragments of tongue were fixed in modified Karnovsky's fixative solution. Subsequently, the specimens were treated with 10% NaOH solution for ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-17.455

    authors: Silva MC,Watanabe I,Kronka MC

    更新日期:2002-04-01 00:00:00

  • Expression pattern of the endoplasmic reticulum stress protein gp96 in monophasic and chronic relapsing form of experimental autoimmune encephalomyelitis in rats.

    abstract::Gp96 is the endoplasmic reticulum (ER)-resident molecular chaperone, which is involved in the correction of unfolded proteins, in the activation of proteasome-dependent ER-associated degradation of the misfolded proteins, and in activation of the protein translation that modulates polypeptide traffic into the ER. Furt...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-28.61

    authors: Jakovac H,Grebic D,Barac-Latas V,Mrakovcic I,Radosevic-Stasic B

    更新日期:2013-01-01 00:00:00

  • Molecules of cell adhesion and extracellular matrix proteolysis in oral squamous cell carcinoma.

    abstract::Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity with a poor 5-year survival rate, due in large part to the presence of metastatic disease at initial diagnosis. In recent years, a number of studies have examined the oral tumor microenvironment to asses the potential dynamic balance ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-25.917

    authors: Shi Z,Stack MS

    更新日期:2010-07-01 00:00:00

  • Collagen-platelet interaction: platelet non-integrin receptors.

    abstract::Platelet-collagen interaction is a complex event that involves ligand-receptor interaction. There are many adhesive non-integrin receptors for platelets to interact with various types of collagens. These non-integrin receptors also serve as signal transducers both from the outside of platelets to the inside and possib...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-14.579

    authors: Chiang TM

    更新日期:1999-04-01 00:00:00

  • Antioxidant enzymes in renal cell carcinoma.

    abstract::The aim of the study was to estimate the significance of oxidative/nitrosative damage and expression of antioxidant enzymes in renal cell carcinomas (RCC). For this we investigated immunohistochemically six antioxidant enzymes (AOEs) including MnSOD, ECSOD, thioredoxin, thioredoxin reductase, and gammaglutamyl cystein...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-21.157

    authors: Soini Y,Kallio JP,Hirvikoski P,Helin H,Kellokumpu-Lehtinen P,Tammela TL,Peltoniemi M,Martikainen PM,Kinnula LV

    更新日期:2006-02-01 00:00:00

  • Innervation of the canine mammary gland: an immunohistochemical study.

    abstract::The distribution of peptidergic nerves in canine mammary tissues was studied by immunohistochemical techniques. In addition, the general and the noradrenergic innervations were demonstrated using protein gene product 9.5 and tyrosine hydroxylase immunoreactivities as markers, respectively. Tissue specimens from the ca...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-22.1175

    authors: Pinho MS,Gulbenkian S

    更新日期:2007-11-01 00:00:00

  • Acetylcholinesterase-positive afferent axons in mucosa of urinary bladder of adult cats: retrograde tracing and degeneration studies.

    abstract::Acetylcholinesterase (AchE)-positive afferent axons in the mucosa of the cat urinary bladder were examined in the present experiments. Small-sized dorsal root ganglion cells containing AchE enzyme activity were labelled by injection of retrograde tracer (wheat germ agglutinin conjugated to enzymatically inactive horse...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Wakabayashi Y,Kojima Y,Makiura Y,Tomoyoshi T,Maeda T

    更新日期:1995-07-01 00:00:00

  • Advances in translational orthopaedic research with species-specific multipotent mesenchymal stromal cells derived from the umbilical cord.

    abstract::Compliance with current regulations for the development of innovative medicines require the testing of candidate therapies in relevant translational animal models prior to human use. This poses a great challenge when the drug is composed of cells, not only because of the living nature of the active ingredient but also...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-18-249

    authors: Ramallo M,Carreras-Sánchez I,López-Fernández A,Vélez R,Aguirre M,Feldman S,Vives J

    更新日期:2020-09-11 00:00:00

  • Molecular and morphological characterization of neural tube defects in embryos of diabetic Swiss Albino mice.

    abstract:BACKGROUND AND RESULTS:Embryos from diabetic mice exhibit several forms of neural tube defects, including non-closure of the neural tube. In the present study, embryos collected at embryonic day 11.5 from diabetic pregnancies displayed open neural tube with architectural disruption of the surrounding tissues. The perce...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-26.965

    authors: Loh WT,Dheen ST,Jiang B,Kumar SD,Tay SS

    更新日期:2011-08-01 00:00:00

  • Epidemiology and molecular biology of gastrointestinal stromal tumors (GISTs): a population-based study in the South of Switzerland, 1999-2005.

    abstract::Introduction. Gastrointestinal stromal tumors (GISTs) are characterized at the molecular level by c-kit or PDGFRA oncogene mutations. Although GISTs raised major interest in past decades, population-based studies are still rare. Materials and Methods. All GISTs diagnosed in Southern Switzerland (1999-2005) were identi...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-23.1379

    authors: Mazzola P,Spitale A,Banfi S,Mazzucchelli L,Frattini M,Bordoni A

    更新日期:2008-11-01 00:00:00

  • Effect of chronic alcoholism on the human hippocampus.

    abstract::The effect of chronic alcoholism on the human hippocampus was studied in 21 patients, divided in 4 groups: Group A under 45 years, group B 46-59 years, group C 60-69, and Group D over 70 years; and compared with age-matched control patients who died without neurological complications. The gyrus dentatus and the ammoni...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Bengochea O,Gonzalo LM

    更新日期:1990-07-01 00:00:00

  • Complex and elementary histological scoring systems for articular cartilage repair.

    abstract::The repair of articular cartilage defects is increasingly moving into the focus of experimental and clinical investigations. Histological analysis is the gold standard for a valid and objective evaluation of cartilaginous repair tissue and predominantly relies on the use of established scoring systems. In the past thr...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-11-620

    authors: Orth P,Madry H

    更新日期:2015-08-01 00:00:00

  • Effects of orexins A and B on the secretory and proliferative activity of immature and regenerating rat adrenal glands.

    abstract::Orexins A and B are two hypothalamic peptides, involved in the central regulation of feeding, which act through two receptor subtypes, named OX1R and OX2R. OX1R is selective for orexin-A, and OX2R binds both orexins. We have investigated the effects of three subcutaneous injections of 10 nmol/kg body weight of orexins...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-16.713

    authors: Malendowicz LK,Jedrzejczak N,Belloni AS,Trejter M,Hochól A,Nussdorfer GG

    更新日期:2001-07-01 00:00:00

  • Apocrine secretory mechanism: recent findings and unresolved problems.

    abstract::Cell secretion is an important physiological process that ensures smooth metabolic activities, tissue repair and growth and immunological functions in the body. It occurs when the intracellular secretory materials are released to the exterior; these may be in the form of lipids, protein or mucous and may travel throug...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-18.597

    authors: Gesase AP,Satoh Y

    更新日期:2003-04-01 00:00:00

  • Facilitating tailored therapeutic strategies for glioblastoma through an orthotopic patient-derived xenograft platform.

    abstract::Despite years of research into its pathobiology and continuing clinical trials for novel therapies, the prognosis for patients with glioblastoma (GBM) remains dismal. An important obstacle against treatment efficacy may be a high degree of intra- and inter-tumoral heterogeneity within GBMs, which may be caused by the ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-11-695

    authors: Lee HW,Lee K,Kim DG,Yang H,Nam DH

    更新日期:2016-03-01 00:00:00