Advances in translational orthopaedic research with species-specific multipotent mesenchymal stromal cells derived from the umbilical cord.

abstract：:Nitric oxide (NO) has opened a new and vigorous field of biological and clinical experimentation as evidenced presently by about one hundred original publications every week. Being a biological signal under physiological conditions, NO may be to pathologically affected tissues. Major insights into the ...

journal_title：Histology and histopathology

authors： Wolf G

更新日期：1997-01-01 00:00:00

abstract：:A variety of studies have shown that incubation of different tumour cell lines with mistletoe lectins (MLs) in vitro has a marked cytotoxic effect. In the concentration range of low cytotoxicity cell death induced by ML-I is quantitatively due to apoptotic processes. The first events observed being membrane perforatio...

journal_title：Histology and histopathology

authors： Pryme IF,Bardocz S,Pusztai A,Ewen SW

更新日期：2006-03-01 00:00:00

abstract：:Strain injuries of tendons are the most common orthopedic injuries in athletic subjects, be they equine or human. When the tendon is suddenly damaged, an acute inflammatory phase occurs whereas its repetitive overloading may cause chronic injuries. Currently the criteria used for grading injuries are general and subje...

journal_title：Histology and histopathology

authors： Martinello T,Pascoli F,Caporale G,Perazzi A,Iacopetti I,Patruno M

更新日期：2015-08-01 00:00:00

abstract：:The characteristics and distribution pattern of retinal afferent terminals making synaptic contacts on narrow field vertical neurons in the stratum griseum superficiale of the rabbit superior colliculus were studied using the Golgi-gold substitution technique in combination with either autoradiographic or degenerative...

journal_title：Histology and histopathology

authors： Ortega F,Doñate-Oliver F,Grandes P

更新日期：1993-01-01 00:00:00

abstract：:A number of tumor suppressor and tumor-related genes exhibit promoter hypermethylation with resulting gene silencing in human cancers. In addition, several gene promoters have also been shown to become hypermethylated in non-neoplastic cells during aging. To assess the physiological consequence and clinical significan...

journal_title：Histology and histopathology

authors： Tamura G

更新日期：2004-01-01 00:00:00

abstract：:The adrenal glands of lower vertebrates display a notable intermingling between steroidogenic and chromaffin tissues, which increases from Pisces to Aves. As in mammals, adrenal chromaffin cells contain and release, in addition to catecholamines, serotonin and several peptides, which may affect the secretory activity ...

journal_title：Histology and histopathology

authors： Mazzocchi G,Gottardo G,Nussdorfer GG

更新日期：1998-01-01 00:00:00

abstract：:Many surgical techniques are employed in the treatment of severe obesity. A main consequence of these techniques is the improvement of type 2 Diabetes mellitus. Ghrelin is a gut hormone released in the gastric fundus and corpus, which has been related to diabetic improvement as mentioned in these papers. Sleeve gastre...

journal_title：Histology and histopathology

authors： Camacho-Ramírez A,Mayo-Ossorio MÁ,Pacheco-García JM,Almorza-Gomar D,Ribelles-García A,Belmonte-Núñez A,Prada-Oliveira JA,Pérez-Arana GM

更新日期：2020-08-01 00:00:00

abstract：:We examined the relationship between the incidence of ultrastructural changes in the alveolar septum and the extravascular lung water content. Pulmonary edema was induced in 18 mongrel dogs by either dextran (n = 12) or alloxan (n = 6) administration. Six other dogs served as controls. Extravascular lung water content...

journal_title：Histology and histopathology

authors： Oda H,Arakawa M,Kambara K,Nakahara K,Segawa T,Ando F,Kawada T,Hirakawa S,Shoumura S,Isono H

更新日期：1993-01-01 00:00:00

abstract：:Phagocytosis is an important feature of innate immunity in which invading microorganisms are engulfed, killed and degraded - and in some immune cells, their antigens presented to adaptive immune system. A closely related process, efferocytosis, removes apoptotic cells, and is essential for the maintenance of homeostas...

journal_title：Histology and histopathology

authors： Taefehshokr N,Yin C,Heit B

更新日期：2020-09-29 00:00:00

abstract：:Targeting essential cellular pathways that determine neuronal and vascular survival can foster a successful therapeutic platform for the treatment of a wide variety of degenerative disorders in the central nervous system. In particular, oxidative cellular injury can precipitate several nervous system disorders that ma...

journal_title：Histology and histopathology

authors： Chong ZZ,Maiese K

更新日期：2004-04-01 00:00:00

abstract：:We designed to investigate the effects of down-regulating the tumor susceptibility gene 101 (TSG101) on the proliferation and apoptosis of the human breast cancer MCF-7 cell line, and the role of the MAPK/ERK signal pathway in this process. The siRNA against TSG101 was transfected into the breast cancer MCF-7 cell lin...

journal_title：Histology and histopathology

authors： Zhang Y,Song M,Cui ZS,Li CY,Xue XX,Yu M,Lu Y,Zhang SY,Wang EH,Wen YY

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Protein tyrosine kinase 7 (PTK7) is a member of receptor protein tyrosine kinase-like molecules, which is involved in tumorigenesis. However, the association between PTK7 expression and its pathological significance in survival prognosis remains under investigation. The purpose of this meta-analysis is to cl...

journal_title：Histology and histopathology

authors： Chen G,Qi S,Yang X,Chen W

更新日期：2018-04-01 00:00:00

abstract：:It has been commonly supposed that adult stem cells co-localize with supporting cells within specific regions or specialized microenvironment in each tissue/organ, called stem cell niche. This concept was based on the assumption that stem cells are intrinsically hierarchical in nature. However, recent data indicate th...

journal_title：Histology and histopathology

authors： Deregibus MC,Tetta C,Camussi G

更新日期：2010-03-01 00:00:00

abstract：:Cerebral cavernous malformations (CCMs) are described as vascular lesions consisting of endothelial-lined dilated vessels embedded in a connective tissue sheath without intervening parenchyma between them. Their anatomical connections with the normal blood vessels are still enigmatic and the fine three-dimensional (3-...

journal_title：Histology and histopathology

authors： Toralba S,Landemore G,Coquemont M,Plancoulaine B,Chapon F

更新日期：2014-08-01 00:00:00

abstract：:Angiogenesis and bone formation are coupled during skeletal development and fracture healing. This relationship, although known for some time, has not been properly explored. Advances in the discovery of how angiogenesis is regulated in physiological processes like embryogenesis, endometrial regeneration and wound hea...

journal_title：Histology and histopathology

authors： Portal-Núñez S,Lozano D,Esbrit P

更新日期：2012-05-01 00:00:00

abstract：:Huntington's disease (HD) is a tremendously debilitating disorder that strikes relatively young individuals and progresses rapidly over the next ten to fifteen years inducing a loss of cognitive and motor skills and eventually death occurs. The primary locus of the disorder is a polyglutamine expansion of the protein ...

journal_title：Histology and histopathology

authors： Martin B,Golden E,Keselman A,Stone M,Mattson MP,Egan JM,Maudsley S

更新日期：2008-02-01 00:00:00

abstract：:Autophagy and apoptosis are two important molecular mechanisms that maintain cellular homeostasis under stress conditions. Autophagy represents an intracellular mechanism responsible for turnover of organelles and long-lived proteins through a lysosome-dependent degradation pathway. Cell death signals or sustained str...

journal_title：Histology and histopathology

authors： Oral O,Akkoc Y,Bayraktar O,Gozuacik D

更新日期：2016-05-01 00:00:00

abstract：:The changes of implanted Harding-Passey melanoma in C57Bl/6J mice following treatment with wholebody hyperthermia were studied. The treated tumours showed a progressive growth delay, cellular and architectural irregularities as well as cell injury characteristics. The presence of distended and irregular blood vessels,...

journal_title：Histology and histopathology

authors： Vicente V,Gómez M,Gómez S,Calderon F,Canteras M,Cremades A

更新日期：1987-10-01 00:00:00

abstract：:Actin microfilaments and microtubules are important cytoskeletal proteins that regulate endothelial repair through alterations in cell shape and through regulation of cell migration following wounding of the endothelium. Upstream pathways have been identified in the regulation of actin and microtubule organization, es...

journal_title：Histology and histopathology

authors： Lee JS,Gotlieb AI

更新日期：2003-07-01 00:00:00

abstract：:Detailed characterization of the subdermal model is a significant tool for better understanding of calcification mechanisms occurring in heart valves. In previous ultrastructural investigation on six-week-implantated aortic valve leaflets, modified pre-embedding glutaraldehyde-cuprolinic-blue reactions (GA-CB) enabled...

journal_title：Histology and histopathology

authors： Ortolani F,Bonetti A,Tubaro F,Petrelli L,Contin M,Nori SL,Spina M,Marchini M

更新日期：2007-03-01 00:00:00

abstract：:There is scarce information on the possible effects of chronic exposure to mercury on skeletal muscle. Dental personnel are frequently exposed to inhalation of metallic mercury vapours. The skeletal muscle of five technicians and one dentist (females, age 36-55) was studied. All of them presented symptoms of chronic m...

journal_title：Histology and histopathology

authors： Nadorfy-López E,Torres SH,Finol H,Méndez M,Bello B

更新日期：2000-07-01 00:00:00

abstract：:HPV infection has been identified recently as the causative agent of a subset of squamous cell carcinomas arising in oropharyngeal tonsils. Factors influencing the susceptibility of tonsillar epithelium to HPV-induced oncogenesis are far from being elucidated. A 5-protein signature including cytokeratin (CK)7, anterio...

journal_title：Histology and histopathology

authors： Morbini P,Capello GL,Alberizzi P,Benazzo M,Paglino C,Comoli P,Pedrazzoli P

更新日期：2015-07-01 00:00:00

abstract：:Smads are signal transducers for the members of the TGF-beta superfamily. Of these Smads, Smad4 is essential for TGF-beta signaling. The purpose of this study was to elucidate Smad4 expression and localization in 65 gastric adenomas, 49 intestinal-type and 39 diffuse type of gastric adenocarcinomas (including 12 cases...

journal_title：Histology and histopathology

authors： Kim JY,Park DY,Kim GH,Choi KU,Lee CH,Huh GY,Sol MY,Song GA,Jeon TY,Kim DH,Sim MS

更新日期：2005-04-01 00:00:00

abstract：:The anti-oxidant food additive, butylated hydroxytoluene (BHT), was fed to Sprague-Dawley rats at three concentrations: 0.2%, 0.4% and 0.8% for periods of 6, 12, 18 and 24 weeks, and the results were compared with corresponding groups treated with a potent carcinogen, 7,12-dimethylbenz[a]anthracene (DMBA) groups, with...

journal_title：Histology and histopathology

authors： Safer AM,al-Nughamish AJ

更新日期：1999-04-01 00:00:00

abstract：:Neurodegenerative and muscle diseases bear both complex and multifactorial pathologies. An efficacious and robust therapeutic option to treat these diseases is yet to be elucidated. At such a time, mesenchymal stem cells have drawn significant attention due to their immunomodulatory and regenerative properties. Accumu...

journal_title：Histology and histopathology

authors： Lee NK,Na DL,Chang JW

更新日期：2018-07-01 00:00:00

abstract：:Studies in a canine bronchogenic carcinoma model indicate that alveolar type II cells may differentiate from carcinogen-exposed epithelium of larger bronchi and generate adenocarcinomas with bronchioloalveolar and other growth patterns. In this study, we investigated whether type II cells are one of the major prolifer...

journal_title：Histology and histopathology

authors： Ten Have-Opbroek AA,Benfield JR,van Krieken JH,Dijkman JH

更新日期：1997-04-01 00:00:00

abstract：:The lower respiratory tract of the sheep was studied by light-microscopical immunocytochemistry for serotonin, cholecystokinin, somatostatin, bombesin and calcitonin during different periods of lung development; embryonic, foetal and postnatal. At embryonic period only intraepithelial serotonin-containing cells as sol...

journal_title：Histology and histopathology

authors： Balaguer L,Romano J,Ruiz-Pesini P

更新日期：1992-10-01 00:00:00

abstract：:Systematic studies on hepatic stellate cells and myofibroblasts have so far mainly focused on cells located in the perisinusoidal space of Disse, the so-called littoral compartment. Here, these cells play a key role for intralobular fibrogenesis and sinusoidal capillarization. However, advanced hepatic fibrosis and ci...

journal_title：Histology and histopathology

authors： Zimmermann A,Zimmermann H,Fellay M,Reichen J

更新日期：1999-07-01 00:00:00

abstract：:To understand the role of microtubules and microfilaments in regulating endothelial monolayer integrity and repair, and since microtubules and microfilaments show some co-alignment in endothelial cells, we tested the hypothesis that microtubules organize microfilament distribution. Disruption of microtubules with colc...

journal_title：Histology and histopathology

authors： Lee JS,Gotlieb AI

更新日期：2005-04-01 00:00:00

abstract：:The FHIT gene encompassing the most active common human fragile region, FRA3B, has been proposed as a tumour suppressor gene for important common human carcinomas. The mechanism in which Fhit protein exerts its tumour suppressor activity is still obscure. To further understand the Fhit function associated with its int...

journal_title：Histology and histopathology

authors： Zhao P,Hou N,Lu Y

更新日期：2006-09-01 00:00:00