Killing two birds with one stone: The multifunctional roles of mesenchymal stem cells in the treatment of neurodegenerative and muscle diseases.

abstract：:We review here the 14 members of the Monocarboxylate transporter family (MCTs), their relationship based on sequence homology. The range of substrates transported by different members of this family extends from the standard monocarboxylate metabolites, lactic and pyruvic acids, to aromatic amino acids and thyroid hor...

journal_title：Histology and histopathology

authors： Merezhinskaya N,Fishbein WN

更新日期：2009-02-01 00:00:00

abstract：:The recent discovery of nitric oxide (NO) as a biological messenger molecule with unique characteristics has opened a new field in pineal research. This free radical gas is synthesized by the enzyme nitric oxide synthase (NOS) from L-arginine. The activation of adrenoreceptors in the membrane of the pinealocytes media...

journal_title：Histology and histopathology

authors： López-Figueroa MO,Møller M

更新日期：1996-10-01 00:00:00

abstract：:In the present work a morphopathological study is carried out of the glomerular filtration barrier in 20 Large-White pigs weighing 20 kg, subjected to experimental intravenous inoculations of endotoxin from Salmonella enteritidis. The study is completed with the determination of protein plasmatic levels, through urine...

journal_title：Histology and histopathology

authors： Redondo E,Roncero V,Durán E,Gázquez A

更新日期：1989-10-01 00:00:00

abstract：:In the present study, morphological changes of the exocrine pancreas in rats after pancreatic duct ligation were examined with light microscopy (hematoxylin-eosin, TUNEL, and PCNA staining) and scanning electron microscopy in order to elucidate the effects of increased pancreatic duct pressure. On the fifth day after ...

journal_title：Histology and histopathology

authors： Hamamoto N,Ashizawa N,Niigaki M,Kaji T,Katsube T,Endoh H,Watanabe M,Sumi S,Kinoshita Y

更新日期：2002-10-01 00:00:00

abstract：:Unlike other B cells, plasma cells (PC) react with only a few antibodies against haemopoietic antigens. We investigated 36 specimens exhibiting a reactive increase in PC numbers (i.e. plasmacytosis, PC hyperplasia) with a broad panel of antibodies suitable for use on formalin-fixed, paraffin-embedded tissue, and compa...

journal_title：Histology and histopathology

authors： Beschorner R,Horny HP,Petruch UR,Kaiserling E

更新日期：1999-07-01 00:00:00

abstract：:Oral squamous cell carcinoma is the most common head and neck malignancy, characterised by high invasive capacity, lymph node metastasis, and high recurrence rate. Among the morphological features of oral cancer, the tumour-associated tissue eosinophilia has gained growing interest in the last years. Eosinophils are a...

journal_title：Histology and histopathology

authors： Mascitti M,Togni L,Rubini C,Troiano G,Lo Muzio L,Santarelli A

更新日期：2020-09-28 00:00:00

abstract：:Emperipolesis has recently been described as a constant feature of "biphasic squamoid" papillary renal cell carcinoma (BPRCC). We also noticed this in some high-grade (HG) RCC, which promoted the present study to estimate the incidence of emperipolesis in RCCs and to describe them in further detail. 14 cases of HGRCC ...

journal_title：Histology and histopathology

authors： Rotterova P,Martinek P,Alaghehbandan R,Prochazkova K,Damjanov I,Rogala J,Suster S,Perez-Montiel D,Alvarado-Cabrero I,Sperga M,Svajdler M,Michalova K,Pivovarcikova K,Daum O,Hora M,Dusek M,Ondic O,Stehlikova A,Michal M

更新日期：2018-03-01 00:00:00

abstract：:The clinical presentation, histopathology and immunoelectron microscopic features of two cases of duodenal somatostatinoma are described, one of which is a hitherto unreported example of a collision tumour with a neurofibroma. Ultrastructural morphometric immunoelectron microscopy studies revealed the presence of four...

journal_title：Histology and histopathology

authors： Varikatt W,Yong JL,Killingsworth MC

更新日期：2006-11-01 00:00:00

abstract：:Serotonin-producing pancreatic endocrine tumours are rare neoplasms which in most cases exhibit malignant biological behaviour. These tumours, in the majority of the well-documented cases, are composed of argyrophil- and argentaffin-positive cells which contain large pleomorphic neurosecretory granules. In contrast, a...

journal_title：Histology and histopathology

authors： Kanavaros P,Hoang C,Le Bodic MF,Polivka M,Hautefeuille P

更新日期：1990-07-01 00:00:00

abstract：:Membranous glomerulonephritis caused in Barbus graellsi by myxosporidian infections have been studied by electron microscopy and immunoelectron microscopy techniques. This study indicates that Myxosporidian infection produces a chronic severe aggression. Spores reach the spleen, the kidney and the liver, where they ar...

journal_title：Histology and histopathology

authors： Peribañez MA,del Cacho E,Castillo JA,Arnal MC

更新日期：1993-10-01 00:00:00

abstract：:Although traditionally little attention has been paid to the interplay between neurotrophins and the cell cycle, a number of recent findings suggest an important role for these growth factors in the regulation of this aspect of the cellular physiology. In this article, we review the evidence from a number of studies t...

journal_title：Histology and histopathology

authors： López-Sánchez N,Frade JM

更新日期：2002-10-01 00:00:00

abstract：:This report presents preliminary observations on the distribution of an epithelial surface antigen in human trophoblastic cells studied with the monoclonal antibody Ber-EP4 by means of an immunoperoxidase technique. Three cases of gestational choriocarcinoma and 20 cases of both villous and extravillous trophoblast, i...

journal_title：Histology and histopathology

authors： Babury RA,Moscovic EA

更新日期：1993-04-01 00:00:00

abstract：:Much effort has been made by researchers to elucidate the complex biology of breast cancer stem cells (BCSCs), a small subset of breast tumor cells that display stem cell properties, drive tumor initiation, and growth. In recent years, it has been suggested that BCSCs could be responsible for the process of metastasis...

journal_title：Histology and histopathology

authors： Schwarz-Cruz Y Celis A,Espinosa M,Maldonado V,Melendez-Zajgla J

更新日期：2016-06-01 00:00:00

abstract：:Pulmonary fibrosis is a common response to various injuries to the lung. The resolution of a fibroproliferative response after lung injury is key to survival. Although there are various initiating factors or causes, the terminal stages are characterized by proliferation and progressive accumulation of connective tissu...

journal_title：Histology and histopathology

authors： Kuwano K,Hagimoto N,Nakanishi Y

更新日期：2004-07-01 00:00:00

abstract：:Sample preparation of dental tissues for quantitative electron microprobe analysis has not been critically examined because of the highly mineralized nature of these structures. The present study was designed to establish the most suitable method for the electron probe quantitative determination of calcium in human pe...

journal_title：Histology and histopathology

authors： Sánchez-Quevedo MC,Nieto-Albano OH,García JM,Gómez de Ferraris ME,Campos A

更新日期：1998-01-01 00:00:00

abstract：:The pineal organs of 14-week-old domestic geese were investigated with light and electron microscopy. The pineals consisted of a wide distal part and a narrow middle-proximal one. The glands were attached to the intercommissural region via the choroid plexus. The pineal parenchyma was formed by round or elongated foll...

journal_title：Histology and histopathology

authors： Prusik M,Lewczuk B,Nowicki M,Przybylska-Gornowicz B

更新日期：2006-10-01 00:00:00

abstract：:Primary cultured human salivary gland cells were transfected with ori-defective mutant DNA of SV40. Following 2-3 weeks of transfection, slowly expanding colonies consisting of small compact cells emerged, while mock-transfected cells did not grow any more and eventually entered crisis, followed by cell death. Using l...

journal_title：Histology and histopathology

authors： Azuma M,Sato M

更新日期：1994-10-01 00:00:00

abstract：:Ductular hepatocytes are observed in the livers of both experimental animals and man under various conditions of severe toxin-, carcinogen- or viral-induced hepatic injury with prominent loss of parenchymal hepatocytes. These unique hepatic epithelial cells are characterized by phenotypic traits that are intermediate ...

journal_title：Histology and histopathology

authors： Sirica AE

更新日期：1995-04-01 00:00:00

abstract：:Treatment of neurodegenerative diseases by classical pharmacotherapy is restricted by blood-brain barrier which prevents access to the brain of potentially therapeutic molecules. Recent progress in the knowledge of pathophysiological molecular processes, and in the development of molecular biotechnology have opened th...

journal_title：Histology and histopathology

authors： Giménez y Ribotta M

更新日期：2001-07-01 00:00:00

abstract：:The aim of our study was to document whether relationships existed among bone morphogenetic proteins (BMPs), peripheral nerve and neoplastic lesions of nerve sheath tumors. The mRNA transcriptions of BMP-2, 3, 4 and 5 in 10 cases of schwannoma, three cases of malignant schwannoma and two cases of trigeminal neuralgia ...

journal_title：Histology and histopathology

authors： Jin Y,Lu HB,Liong E,Lau TY,Tipoe GL

更新日期：2001-10-01 00:00:00

abstract：:An ultrastructural and histological study was made to analyse the structural and cellular features of the pulmonary lesions produced in Wistar rats by intraperitoneal (i.p.) administration of cyclophosphamide (two i.p. doses of 150 mg CP/1 kg bw/1 ml PBS). Rats exposed to cyclophosphamide (CP) developed a condition wh...

journal_title：Histology and histopathology

authors： Sulkowski S,Sulkowska M

更新日期：1999-10-01 00:00:00

abstract：:Takeda-G-protein-receptor-5 (TGR5) is a receptor for bile acids and its expression has been described in a variety of tissues and species. Characterization of TGR5 distribution and function has been investigated in drug discovery for the treatment of metabolic diseases in humans. Because dogs are one of the species us...

journal_title：Histology and histopathology

authors： Giaretta PR,Suchodolski JS,Blick AK,Steiner JM,Lidbury JA,Rech RR

更新日期：2019-01-01 00:00:00

abstract：:We review the morphofunctional characteristics of CD34+ stromal fibroblastic/fibrocytic cells (CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ SFCs: A) The confusing terms applied to this cell type, often combining the prefix CD34 with numerous names, including fibroblasts, fibrocyt...

journal_title：Histology and histopathology

authors： Díaz-Flores L,Gutiérrez R,García MP,Sáez FJ,Díaz-Flores L Jr,Valladares F,Madrid JF

更新日期：2014-07-01 00:00:00

abstract：:F10, a subline of the B16 mouse melanoma cell line, is itself the parent of the more metastatic BL6 line. BL6 cells differ from F10 cells by an alteration of the gene encoding the B56gamma regulatory subunit of protein phosphatase 2A (PP2A), which results in mRNA encoding a truncated variant of the subunit (deltagamma...

journal_title：Histology and histopathology

authors： Koma YI,Ito A,Watabe K,Kimura SH,Kitamura Y

更新日期：2004-04-01 00:00:00

abstract：:The view of how astrocytes, a type of glial cells, contribute to the functioning of the central nervous system (CNS) has changed greatly in the last decade. Although glial cells outnumber neurons in the mammalian brain, it was considered for over a century that they played a subservient role to neurons. This view chan...

journal_title：Histology and histopathology

authors： Potokar M,Stenovec M,Kreft M,Gabrijel M,Zorec R

更新日期：2011-02-01 00:00:00

abstract：:Earlier we reported that atherosclerotic lesions of apoE-deficient mice contained cells which stained positively with anti-S-100 antibody and that cells exhibiting the ultrastructural features of dendritic cells were present in the aortic lesions. These observations suggested that dendritic cells might be involved in ...

journal_title：Histology and histopathology

authors： Bobryshev YV,Taksir T,Lord RS,Freeman MW

更新日期：2001-07-01 00:00:00

abstract：:Fluoxetine shows controversial lung effects as it prevents pulmonary hypertension in adult rats but exposure during gestation causes pulmonary hypertension in neonatal rats. In the present study, we tested the null hypothesis that the antidepressant drug fluoxetine does not modify the development of bronchopulmonary d...

journal_title：Histology and histopathology

authors： Porzionato A,Zaramella P,Macchi V,Grisafi D,Salmaso R,Baraldi M,Fornaro E,Tassone E,Masola V,Onisto M,Chiandetti L,De Caro R

更新日期：2012-12-01 00:00:00

abstract：:Recent data challenge the relevance of the RB pathway to cancer based on RB inactivation, at least in breast tumors. To obtain information on the actual role of the components of the RB pathway in tumor progression we decided to investigate whether their quantitative changes were associated with variations in the leve...

journal_title：Histology and histopathology

authors： Montanaro L,Vici M,Donati G,Ceccarelli C,Santini D,Treré D,Derenzini M

更新日期：2007-07-01 00:00:00

abstract：:Three-dimensional characteristics of the epithelial cell layer and connective tissue interface of the tongue were studied using scanning electron microscopy. In this study, the fragments of tongue were fixed in modified Karnovsky's fixative solution. Subsequently, the specimens were treated with 10% NaOH solution for ...

journal_title：Histology and histopathology

authors： Silva MC,Watanabe I,Kronka MC

更新日期：2002-04-01 00:00:00

abstract：:Early observations that cultured mesenchymal stem cells (MSCs) could be induced to exhibit certain characteristics of osteocytes and chondrocytes led to the proposal that they could be transplanted for tissue repair through cellular differentiation. Therefore, many subsequent preclinical studies with transplanted MSCs...

journal_title：Histology and histopathology

authors： Lin CS,Xin ZC,Dai J,Lue TF

更新日期：2013-09-01 00:00:00