Abstract:
:The clinical presentation, histopathology and immunoelectron microscopic features of two cases of duodenal somatostatinoma are described, one of which is a hitherto unreported example of a collision tumour with a neurofibroma. Ultrastructural morphometric immunoelectron microscopy studies revealed the presence of four types of cells in both tumours, but there was no difference in the proportions of these cells between the collision tumour and the non-collision tumour. Neurosecretory granules ranging in size from 255-815 nm were generally larger than those previously reported for somatostatinomas and somatostatin was identified in granules of all sizes across this range. Neither tumour was associated with the somatostatinoma syndrome comprising associated diabetes mellitis, steatorrhoea and cholelithiasis.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Varikatt W,Yong JL,Killingsworth MCdoi
10.14670/HH-21.1171subject
Has Abstractpub_date
2006-11-01 00:00:00pages
1171-80issue
11eissn
0213-3911issn
1699-5848journal_volume
21pub_type
杂志文章abstract::Cyclosporin A is an immunosuppressive drug, which disrupts the activation of peripheral T-lymphocyte pool and blocks the maturation of thymocytes within the thymus. Normally, thymic nonlymphoid cells provide the optimal inductive microenvironment for development of T-lymphocytes. After application of cyclosporin A the...
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journal_title:Histology and histopathology
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journal_title:Histology and histopathology
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