Advances in the knowledge of breast cancer stem cells. A review.

Abstract:

:Much effort has been made by researchers to elucidate the complex biology of breast cancer stem cells (BCSCs), a small subset of breast tumor cells that display stem cell properties, drive tumor initiation, and growth. In recent years, it has been suggested that BCSCs could be responsible for the process of metastasis and the development of drug resistance. These findings make the need to find the distinguishing blend of markers that can recognize only BCSCs of the utmost importance in order to be able to design new targeted therapies. This review will summarize BCSCs' main features as well as the cell surface markers that are currently used to identify them.

journal_name

Histol Histopathol

authors

Schwarz-Cruz Y Celis A,Espinosa M,Maldonado V,Melendez-Zajgla J

doi

10.14670/HH-11-718

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

601-12

issue

6

eissn

0213-3911

issn

1699-5848

pii

HH-11-718

journal_volume

31

pub_type

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