Abstract:
:Within the last few years, advances have been made regarding perivascular nerves and the endothelium of the vascular system, both potentially important in the understanding of the mechanisms of local control of blood flow. Endothelin-1 (ET-1) has been identified in rat cerebrovascular nerves, neuropeptide Y (NPY) has been demonstrated in umbilical endothelium, the arginine-vasopressin (VP) system has been discovered in the heart (including coronary endothelium), and P2X receptors have been observed in vascular endothelial cells. After a brief introduction to vascular biology, this review will focus on the above-mentioned new data.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Loesch Adoi
10.14670/HH-17.591subject
Has Abstractpub_date
2002-04-01 00:00:00pages
591-7issue
2eissn
0213-3911issn
1699-5848journal_volume
17pub_type
杂志文章,评审abstract::This paper reports the histopathological findings in the eyes of a 26-year-old female patient diagnosed with systemic lupus erythematosus (SLE) with peripheral neuropathy. The patient had no significant ocular problems. She died of pneumonia after two years of suffering. The eyeballs were procured at autopsy and the r...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-20.373
更新日期:2005-04-01 00:00:00
abstract::The presence of the mu-opioid receptor and the type of glycosylation in the third extra-cellular loop of this receptor was investigated in the isthmus of mare oviduct during oestrus by means of immunoblotting and immunohistochemistry combined with enzymatic (N-glycosidase F and O-glycosidase) and chemical (beta-elimin...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-23.555
更新日期:2008-05-01 00:00:00
abstract::Many surgical techniques are employed in the treatment of severe obesity. A main consequence of these techniques is the improvement of type 2 Diabetes mellitus. Ghrelin is a gut hormone released in the gastric fundus and corpus, which has been related to diabetic improvement as mentioned in these papers. Sleeve gastre...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-18-200
更新日期:2020-08-01 00:00:00
abstract::A number of tumor suppressor and tumor-related genes exhibit promoter hypermethylation with resulting gene silencing in human cancers. In addition, several gene promoters have also been shown to become hypermethylated in non-neoplastic cells during aging. To assess the physiological consequence and clinical significan...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-19.221
更新日期:2004-01-01 00:00:00
abstract::A method for the in vitro generation of granulomas and its use in the analysis of the human granulomatous response is summarized. As a target for the cellular response L3 larvae of Nippostrongylus brasiliensis are coincubated with human mononuclear blood cells, and within seven to fourteen days the development of bloo...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-16.645
更新日期:2001-04-01 00:00:00
abstract::Recent evidence has shown that vascular function depends not only on cells within the vessels, but is also significantly modulated by circulating cells derived from the bone marrow. A number of studies indicate that an early reendothelialization by circulating endothelial precursors after vascular injury prevents exce...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-22.547
更新日期:2007-05-01 00:00:00
abstract::Sample preparation of dental tissues for quantitative electron microprobe analysis has not been critically examined because of the highly mineralized nature of these structures. The present study was designed to establish the most suitable method for the electron probe quantitative determination of calcium in human pe...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-13.109
更新日期:1998-01-01 00:00:00
abstract::The International Prognostic Index (IPI) has been the basis for determining prognosis in patients with diffuse large B-cell lymphoma (DLBCL) for the past 20 years. The utility of the IPI must be reassessed in the era of immunochemotherapy. Seven risk factors at diagnosis were identified, and a maximum of 7 points were...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-11-673
更新日期:2016-03-01 00:00:00
abstract::CD24 is known to be an important diagnostic and prognostic marker of several major cancers affecting females. We aimed to determine CD24 expression in normal, hyperplastic, and carcinomatous endometrium and its correlation with estrogen and progesterone receptor expression. A total of 271 cases including 62 normal/atr...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-24.309
更新日期:2009-03-01 00:00:00
abstract::The techniques for light and electron microscopic radioautography developed in our laboratory are described. The outlines of the applications to various tissues and organs are also briefly summarized. First, the techniques are explained in detail. These techniques can be divided into two categories, i.e., chemical fix...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:
更新日期:1997-10-01 00:00:00
abstract::Thymidine phosphorylase (TP), thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) have been indicated as possible predictive markers for epithelial malignancies. All these three enzymes are actively involved in 5-FU metabolism. In this report, we investigated mRNA expression of these factors with real-...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-19.129
更新日期:2004-01-01 00:00:00
abstract::Membranous glomerulonephritis caused in Barbus graellsi by myxosporidian infections have been studied by electron microscopy and immunoelectron microscopy techniques. This study indicates that Myxosporidian infection produces a chronic severe aggression. Spores reach the spleen, the kidney and the liver, where they ar...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::The low density lipoprotein receptor-related protein (LRP) 1 is a ubiquitously expressed, versatile cell surface transmembrane receptor involved in embryonic development and adult tissue homeostasis. LRP1 binds and endocytoses a broad spectrum of over 40 ligands identified thus far, including lipoproteins, extracellul...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-11-746
更新日期:2016-07-01 00:00:00
abstract::Knee osteoarthritis (KOA) is the most common progressive joint disorder associated with disability in the world. As a chronic disease, KOA has multifactorial etiology. However, the poor self-healing ability of the articular cartilage due to its intrinsic tissue hypovascularity and hypocellularity seems to be directly ...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-11-955
更新日期:2018-07-01 00:00:00
abstract::The immunohistochemical distribution of 15 blood coagulation factors in the germinal centers (GCs) of human Peyer's patches (PPs) was studied. Although factor VIII, active alpha-thrombin, and fibrinogen were hardly evident in the GCs, the majority of coagulation factors, such as kallikrein, high-molecular-weight kinin...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::To investigate the matrix metalloproteinase (MMP)-9, (MMP)-13, E-Cadherin and Ki-67 expressions in road pavers' skin chronically exposed to bitumen products in order to contribute to a better understanding of the earlier tissue alteration. Skin punch biopsies from 16 daily exposed workers and a control group were stud...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-18-116
更新日期:2019-10-01 00:00:00
abstract::The novel coronavirus disease 2019 (COVID-19) outbreak began in the city of Wuhan, whereupon it rapidly spread throughout China and subsequently across the world. Rapid transmission of COVID-19 has caused wide-spread panic. Many established medications have been used to treat the disease symptoms; however, no specific...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-18-223
更新日期:2020-10-01 00:00:00
abstract::To understand the role of microtubules and microfilaments in regulating endothelial monolayer integrity and repair, and since microtubules and microfilaments show some co-alignment in endothelial cells, we tested the hypothesis that microtubules organize microfilament distribution. Disruption of microtubules with colc...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-20.455
更新日期:2005-04-01 00:00:00
abstract::Oligodendrocytes are the myelinating cells of the central nervous system. Since many studies of demyelinating diseases focus their research on this cell type, there is growing interest for obtaining reliable markers that can specifically recognize oligodendroglia. Established markers are the myelin-associated neurite ...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-11-640
更新日期:2015-12-01 00:00:00
abstract::In recent years, the different mechanisms of epithelial cell loss which occur in mammalian and avian small intestine have been re-investigated. Information is now available for a variety of mammalian types and mechanisms can be divided into two major classes: [i] those preserving epithelial integrity by maintaining in...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-14.257
更新日期:1999-01-01 00:00:00
abstract::Introduction. Lichen planus (LP) is a chronic cytokine-mediated disease of possible auto-immune etiology. 25% of men have anogenital manifestations. Erosive penile LP causes a scarring phimosis of the foreskin in uncircumcised men. Mast cells as potent immune modulators have been implicated in a number of autoimmune a...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-29.1017
更新日期:2014-08-01 00:00:00
abstract::The Libyan jird (Meriones libycus) is a nocturnal Saharan Rodent submitted to a seasonal cycle of reproduction characterized by a short active period during spring and beginning of summer, and a long phase of sexual quiescence from the end of summer until the end of winter. During this cycle, the male reproductive org...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-22.603
更新日期:2007-06-01 00:00:00
abstract::We report a case of subcutaneous fat necrosis of a newborn child which appeared 9 days after birth and was cured without any complications. We propose the reclassification of the etiological factors accompanying this lesion by classifying them in a plurietiological syndrome with some basic or essential factors and oth...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The importance of molybdenum-containing enzymes in the pathophysiology of a number of clinical disorders necessitates a comprehensive understanding of their histological localization and expression. The objectives of this review are to cover such enzymes so far reported and their enzyme- and immunohistochemical locali...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:
更新日期:1997-04-01 00:00:00
abstract::Our previous study on human skeletal muscle undergoing ischemia and reperfusion has revealed that granulocytes, which infiltrate the muscle tissue in large numbers, play an important role in mediating fibre injuries by producing superoxide anion (O2-) which is responsible for membrane lipid peroxidation. In the curren...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract::Identification of robust diagnostic and therapeutic target molecules for human malignancy is still an important issue. If we identify novel proteins which play a stem-line role for cellular transformation or aggravation of malignancy, it could give us a clue to diagnose a tumor in an earlier stage and to develop more ...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-20.999
更新日期:2005-07-01 00:00:00
abstract::Neutrophil extracellular traps (NETs) are innate immune systems against invading pathogens. NETs are characterized as released DNA mixed with cytoplasmic antimicrobial proteins such as myeloperoxidase, proteinase3 and neutrophil elastase. While NETs are thought to have an important role in host defense, recent work ha...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-11-816
更新日期:2017-03-01 00:00:00
abstract::Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for the purpose of anti-inflammation, antipyretic, and analgesia. For this aim, they are used for the alleviation of pain, fever, and inflammation associated with rheumatoid arthritis, sports injuries, and temporary pain. However, treatment with NSAIDs may ...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-27.417
更新日期:2012-04-01 00:00:00
abstract:AIMS:The expression patterns of TGFB signaling proteins, such as TGFB1/2, TGFBR1(ALK5), TGFBR2, SMAD1/2/3, SMAD2/3, SMAD4, SMAD7, and of downstream targets of TGFB signaling, CDKN1A (p21CIP1), CDKN1B (p27KIP1), MYC, CDC25A, TP53, and RELA (p65NF-kB) were investigated in gastric carcinomas and other gastric lesions. ME...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-23.1439
更新日期:2008-12-01 00:00:00
abstract::Huntington's disease (HD) is a tremendously debilitating disorder that strikes relatively young individuals and progresses rapidly over the next ten to fifteen years inducing a loss of cognitive and motor skills and eventually death occurs. The primary locus of the disorder is a polyglutamine expansion of the protein ...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-23.237
更新日期:2008-02-01 00:00:00