Studies with the Golgi method in central gangliogliomas and dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease).

Abstract:

:The rapid Golgi method, combined with current optical and electronmicroscopical techniques, was used in three central gangliogliomas and in one dysplastic gangliocytoma of the cerebellum to study the morphology of ganglionic cells. Gangliogliomas were composed of bipolar, fusiform and radiate cells with dense core and clear vesicles in the perikaryon and cellular processes, the number of each cellular type varying from one case to another. These features, together with the fact that isodendritic neurons are considered to be phylogenetically old neurons, suggest that these tumours are composed of "primitive" neurons that are not homogeneous with regard to their morphology. In contrast, ganglionic cells in dysplastic gangliocytoma are huge cells with long, stereotyped neurites that establish unique asymmetric contacts with neighbouring perikarya and neurites by means of claw-shaped processes covered with synaptic buttons. These morphological characteristics are different from those of any other neuron of the CNS.

journal_name

Histol Histopathol

authors

Ferrer I,Martí E,Guionnet N,Bella R,Serrano T,Towse J,Conesa G,Isamat F

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

329-36

issue

3

eissn

0213-3911

issn

1699-5848

journal_volume

5

pub_type

杂志文章
  • Muscular hypertrophy and atrophy in normal rats provoked by the administration of normal and denervated muscle extracts.

    abstract::This study was conducted to determine the effects of extracts obtained from both normal and denervated muscles on different muscle types. Wistar rats were used and were divided into a control group and four experimental groups. Each experimental group was treated intraperitoneally during 10 consecutive days with a dif...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-11-776

    authors: Agüera E,Castilla S,Luque E,Jimena I,Leiva-Cepas F,Ruz-Caracuel I,Peña J

    更新日期:2016-12-01 00:00:00

  • Microglia and prion disease: a review.

    abstract::Prion diseases are characterized by the accumulation of PrPSc, an altered isoform of a normal cellular protein, PrPc. The prion hypothesis holds that the process of conformational change from PrPc to PrPSc under the influence of PrPSc constitutes the basic infectious mechanism in prion diseases. It is still unknown wh...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:

    authors: Brown DR,Kretzschmar HA

    更新日期:1997-07-01 00:00:00

  • Structural and ultrastructural hepatic changes in experimental canine leishmaniasis.

    abstract::Six 4 month-old beagles were inoculated with Leishmania donovani infantum, three of them intraperitoneally (Group A) and the other three intravenously (Group B). The animals from Group A were killed 109, 433 and 592 days after inoculation and animals from Group B 109, 171 and 334 after inoculation. The liver of each o...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: González JL,Rollán E,Novoa C,Castaño M

    更新日期:1988-10-01 00:00:00

  • Oxidized regenerated cellulose does not prevent the formation of experimental postoperative perineural fibrosis assessed by digital analysis.

    abstract:INTRODUCTION:It is difficult to prevent and treat intra- and peri-neural fibrosis after peripheral nerve surgery. Many authors have attempted to develop and verify the effectiveness of substances to decrease the formation of adherences in different tissues. MATERIAL AND METHODS:this study aimed to assess the effective...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-25.741

    authors: Hernández-Cortés P,Peregrina M,Aneiros-Fernández J,Tassi M,Pajares-López M,Toledo M,O'Valle F

    更新日期:2010-06-01 00:00:00

  • Understanding the role of the cytoskeleton in the complex regulation of the endothelial repair.

    abstract::Actin microfilaments and microtubules are important cytoskeletal proteins that regulate endothelial repair through alterations in cell shape and through regulation of cell migration following wounding of the endothelium. Upstream pathways have been identified in the regulation of actin and microtubule organization, es...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-18.879

    authors: Lee JS,Gotlieb AI

    更新日期:2003-07-01 00:00:00

  • Induction of pluripotency in primordial germ cells.

    abstract::Primordial germ cells (PGCs) are the founder cells of all gametes. PGCs differentiate from pluripotent epiblasts cells by mesodermal induction signals during gastrulation. Although PGCs are unipotent cells that eventually differentiate into only sperm or oocytes, they dedifferentitate to pluripotent stem cells known a...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-26.643

    authors: Kimura T,Nakano T

    更新日期:2011-05-01 00:00:00

  • Temporal and spatial distribution of TGF-beta isoforms and signaling intermediates in corneal regenerative wound repair.

    abstract::The present study analyzed the temporal and spatial expression of TGF-beta isoforms and activated pSmad2 and p38MAPK during epithelial debridement wound repair, using chick cornea by immunohistochemistry. Normal corneas showed low-level TGF-betas staining. Following wounding, TGF-beta1 expression was strong in the Bow...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-24.1405

    authors: Huh MI,Chang Y,Jung JC

    更新日期:2009-11-01 00:00:00

  • Down-regulation of TSG101 by small interfering RNA inhibits the proliferation of breast cancer cells through the MAPK/ERK signal pathway.

    abstract::We designed to investigate the effects of down-regulating the tumor susceptibility gene 101 (TSG101) on the proliferation and apoptosis of the human breast cancer MCF-7 cell line, and the role of the MAPK/ERK signal pathway in this process. The siRNA against TSG101 was transfected into the breast cancer MCF-7 cell lin...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-26.87

    authors: Zhang Y,Song M,Cui ZS,Li CY,Xue XX,Yu M,Lu Y,Zhang SY,Wang EH,Wen YY

    更新日期:2011-01-01 00:00:00

  • Targeting WNT, protein kinase B, and mitochondrial membrane integrity to foster cellular survival in the nervous system.

    abstract::Targeting essential cellular pathways that determine neuronal and vascular survival can foster a successful therapeutic platform for the treatment of a wide variety of degenerative disorders in the central nervous system. In particular, oxidative cellular injury can precipitate several nervous system disorders that ma...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-19.495

    authors: Chong ZZ,Maiese K

    更新日期:2004-04-01 00:00:00

  • Cape Town solution in prolonged myocardial preservation: structural and ultrastructural study.

    abstract::This study deals with myocardial preservation after 24 hours of continuous, hypothermic and oxygenated perfusion with Cape Town (CT) solution, focusing on the morphological changes produced by preservation and reperfusion, and their possible relationship to the composition of the solution and the immediate hemodynamic...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-13.21

    authors: García-Poblete E,Alvarez L,Fernández H,Escudero C,Torralba A

    更新日期:1998-01-01 00:00:00

  • Oligodendroglial markers in the cuprizone model of CNS de- and remyelination.

    abstract::Oligodendrocytes are the myelinating cells of the central nervous system. Since many studies of demyelinating diseases focus their research on this cell type, there is growing interest for obtaining reliable markers that can specifically recognize oligodendroglia. Established markers are the myelin-associated neurite ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-11-640

    authors: Salinas Tejedor L,Gudi V,Kucman V,Pul R,Gingele S,Sühs KW,Stangel M,Skripuletz T

    更新日期:2015-12-01 00:00:00

  • Killing two birds with one stone: The multifunctional roles of mesenchymal stem cells in the treatment of neurodegenerative and muscle diseases.

    abstract::Neurodegenerative and muscle diseases bear both complex and multifactorial pathologies. An efficacious and robust therapeutic option to treat these diseases is yet to be elucidated. At such a time, mesenchymal stem cells have drawn significant attention due to their immunomodulatory and regenerative properties. Accumu...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-11-951

    authors: Lee NK,Na DL,Chang JW

    更新日期:2018-07-01 00:00:00

  • Antioxidant enzymes in renal cell carcinoma.

    abstract::The aim of the study was to estimate the significance of oxidative/nitrosative damage and expression of antioxidant enzymes in renal cell carcinomas (RCC). For this we investigated immunohistochemically six antioxidant enzymes (AOEs) including MnSOD, ECSOD, thioredoxin, thioredoxin reductase, and gammaglutamyl cystein...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-21.157

    authors: Soini Y,Kallio JP,Hirvikoski P,Helin H,Kellokumpu-Lehtinen P,Tammela TL,Peltoniemi M,Martikainen PM,Kinnula LV

    更新日期:2006-02-01 00:00:00

  • Bronchial-associated lymphoid tissue (BALT) response to airway challenge with cigarette smoke, bovine antigen and anti-pulmonary serum.

    abstract::The bronchial-associated lymphoid tissue (BALT) is a lymphoepithelial organ, related to the immune defence of the lung and to alveolar clearance, which changes size in certain states of disease. Changes in the size of BALT were quantified and compared, and Spearman's test was used to test the relation with the bronchi...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Escolar Castellón JD,Escolar Castellón A,Roche Roche PA,Miñana Amada C

    更新日期:1992-07-01 00:00:00

  • Differential severity of LPS-induced lung injury in CD26/DPP4 positive and deficient F344 rats.

    abstract:BACKGROUND:Lipopolysaccharide (LPS) induced inflammation often leads to lung injury, in which pulmonary recruitment of neutrophils plays a pivotal role. Inflammatory processes are influenced by CD26/DPP4, highly expressed in lungs. Asthma induced CD26/DPP4 deficient (CD26/DPP4⁻) Fischer (F) 344 rats suffering from a tr...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-18-117

    authors: Zientara A,Stephan M,von Hörsten S,Schmiedl A

    更新日期:2019-10-01 00:00:00

  • Review of renal oncocytosis (multiple oncocytic lesions) with focus on clinical and pathobiological aspects.

    abstract::Renal oncocytosis is a recently established disease entity characterized by numerous oncocytic tumors and diffuse involvement of oncocytic changes in renal parenchymal epithelia. In this article, we review this disease with a focus on its clinical and pathobiological aspects. Clinically, renal oncocytosis may occur in...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-27.1407

    authors: Kuroda N,Tanaka A,Ohe C,Mikami S,Nagashima Y,Sasaki T,Inoue K,Hes O,Michal M,Brunelli M,Martignoni G

    更新日期:2012-11-01 00:00:00

  • Transcriptional mRNA of BMP-2, 3, 4 and 5 in trigeminal nerve, benign and malignant peripheral nerve sheath tumors.

    abstract::The aim of our study was to document whether relationships existed among bone morphogenetic proteins (BMPs), peripheral nerve and neoplastic lesions of nerve sheath tumors. The mRNA transcriptions of BMP-2, 3, 4 and 5 in 10 cases of schwannoma, three cases of malignant schwannoma and two cases of trigeminal neuralgia ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-16.1013

    authors: Jin Y,Lu HB,Liong E,Lau TY,Tipoe GL

    更新日期:2001-10-01 00:00:00

  • Immunohistochemical demonstration of metallothionein in benign and malignant canine mammary tumours.

    abstract::Immunocytochemical demonstration of metallothionein (MT) has been reported as a useful prognostic tool in human breast cancer. The aim of this study was to determine the immunohistochemical location of MT in canine mammary tumours and its possible correlation with the morphologic characteristics of these tumours. Surg...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-14.51

    authors: Fuentealba IC,Mullins JE

    更新日期:1999-01-01 00:00:00

  • Telocytes and lung disease.

    abstract::Telocytes (TCs) represent a new distinct type of interstitial cells found in many organs, including lungs. TCs are mainly defined by a small cellular body from which arise very long (hundreds of micrometers) extensions named telopodes. During the last years, TCs were characterized in respect with their microRNA profil...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-11-807

    authors: Song D,Cretoiu D,Cretoiu SM,Wang X

    更新日期:2016-12-01 00:00:00

  • Effect of irradiation on autogenous bone transplantation in rat parietal bone.

    abstract::To determine the appropriate time for bone reconstruction after irradiation, the healing process after autogenous iliac bone transplantation in the irradiated parietal bone was examined by scanning electron microscopy and light microscopy. Bone transplantation was carried out at the second and the fourth weeks after C...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-15.7

    authors: Takekawa M,Matsuda M,Ohotubo S

    更新日期:2000-01-01 00:00:00

  • Ultrastructural analysis of HNK-1+ cells in human peripheral blood and lymph nodes.

    abstract::HNK-1 positive (HNK-1+) cells in human peripheral blood and lymph nodes were comparatively analysed by means of immunohistochemistry and immunoelectron microscopy. In peripheral blood, the HNK-1+ cells were grouped into large granular lymphocytes (LGLs), small lymphocytes and intermediate forms, all of which had many ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Yuda F,Terashima K,Dobashi M,Ishikawa M,Imai Y

    更新日期:1989-04-01 00:00:00

  • Bone marrow stromal cells for spinal cord repair: a challenge for contemporary neurobiology.

    abstract::In the last years, it has been reported that bone marrow stromal cells (BMSC) are able to differentiate towards a neuronal phenotype, in vitro as well as in vivo, and consequently, the possible use of these cells for the treatment of neurological diseases has acquired enormous importance. The objective of this review ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-24.107

    authors: Vaquero J,Zurita M

    更新日期:2009-01-01 00:00:00

  • Pathological changes in dendrites of substantia nigra neurons in Parkinson's disease: a Golgi study.

    abstract::Neurons of the substantia nigra show severe morphological changes in Parkinson's disease. Pathological alterations of cell bodies have been described, whereas those of neuronal processes have hardly been investigated. Golgi impregnation has been the chosen method for demonstrating neuronal processes and dendritic and ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Patt S,Gertz HJ,Gerhard L,Cervós-Navarro J

    更新日期:1991-07-01 00:00:00

  • Ischemia-reperfusion of human skeletal muscle during aortoiliac surgery: effects of acetylcarnitine.

    abstract::Our previous study on human skeletal muscle undergoing ischemia and reperfusion has revealed that granulocytes, which infiltrate the muscle tissue in large numbers, play an important role in mediating fibre injuries by producing superoxide anion (O2-) which is responsible for membrane lipid peroxidation. In the curren...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Adembri C,Domenici LL,Formigli L,Brunelleschi S,Ferrari E,Novelli GP

    更新日期:1994-10-01 00:00:00

  • Neutrophil gelatinase-associated lipocalin (NGAL) immunohistochemical expression in follicular cell-derived thyroid tumors: a novel diagnostic tool?

    abstract::Discrimination of follicular cell-derived benign and malignant tumors of the thyroid is one of the major problems encountered in surgical pathology. In the present study, we evaluated the immunohistochemical expression of NGAL, an iron-binding protein involved in the infiltrative potential of cancer cells, in a cohort...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-27.329

    authors: Barresi V,Leni A,Tuccari G,Barresi G

    更新日期:2012-03-01 00:00:00

  • Effects of orexins A and B on the secretory and proliferative activity of immature and regenerating rat adrenal glands.

    abstract::Orexins A and B are two hypothalamic peptides, involved in the central regulation of feeding, which act through two receptor subtypes, named OX1R and OX2R. OX1R is selective for orexin-A, and OX2R binds both orexins. We have investigated the effects of three subcutaneous injections of 10 nmol/kg body weight of orexins...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-16.713

    authors: Malendowicz LK,Jedrzejczak N,Belloni AS,Trejter M,Hochól A,Nussdorfer GG

    更新日期:2001-07-01 00:00:00

  • Farnesoid X Receptor (FXR) from normal to malignant state.

    abstract::The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of ligand-activated transcription factors, which plays crucial role in bile acid, cholesterol, lipid and glucose metabolism, as well as in the development of atherosclerosis, intestinal bacterial growth and liver regeneration. FXR is also i...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-27.835

    authors: Koutsounas I,Giaginis C,Theocharis S

    更新日期:2012-07-01 00:00:00

  • Less gelatinases is associated with apolipoprotein E accumulation in glomerulosclerosis rats.

    abstract:BACKGROUND:Gelatinases include matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9). The abnormal expressions of gelatinases are implicated in the pathogenesis of extracellular matrix (ECM) accumulation. Apolipo-protein E (apoE) is an important plasma protein in cholesterol homeostasis and plays a ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-27.249

    authors: Zhou TB,Qin YH,Lei FY,Su LN,Zhao YJ,Huang WF

    更新日期:2012-02-01 00:00:00

  • Comparative in vivo and in vitro models to approach the cellular basis of endotoxic shock. The role of sinusoidal liver cells.

    abstract::During endotoxic shock, the liver exerts a lipopolysaccharide (LPS) clearance function with the participation of both parenchymal and sinusoidal cells. Liver damage could be caused by LPS direct action, hypoxia and/or inflammatory mediators released by Kupffer cells. The aim of this study is to establish an experiment...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Pagani R,Portolés MT,Arahuetes R,Ainaga MJ,Machín C,Rua C

    更新日期:1996-07-01 00:00:00

  • Ultrastructural evidence in vitro of osteoclast-induced degradation of calcium phosphate ceramic by simultaneous resorption and phagocytosis mechanisms.

    abstract::Osteoclasts are physiological polykaryons specialized in the resorption of calcified tissue. In the context of the clinical use of calcium-phosphate (CaP) ceramics as bone substitutes, this study used transmission electron microscopy to investigate the in vitro mechanisms of CaP ceramic degradation by osteoclastic cel...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-16.37

    authors: Heymann D,Guicheux J,Rousselle AV

    更新日期:2001-01-01 00:00:00