Abstract：
:The lower respiratory tract of the sheep was studied by light-microscopical immunocytochemistry for serotonin, cholecystokinin, somatostatin, bombesin and calcitonin during different periods of lung development; embryonic, foetal and postnatal. At embryonic period only intraepithelial serotonin-containing cells as solitary neuroendocrine cells (NEC) and neuroepithelial bodies (NEB) were found. At foetal stages, immunoreactive cells to serotonin, cholecystokinin and somatostatin were observed in airway epithelium, as solitary NEC and NEBs, and in autonomic intrapulmonary ganglia as single or clusters of small intensely-fluorescent (SIF) cells. In postnatal sheep, serotonin- and cholecystokinin-containing cells were found within airway mucosa as solitary NECs and NEBs. No immunoreactive cells were observed with antiserum to bombesin and calcitonin. Quantitative studies showed that serotonin was the predominant substance, and that solitary neuroendocrine cells were more numerous in distal conducting airways and at foetal stages.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Balaguer L,Romano J,Ruiz-Pesini Psubject
Has Abstractpub_date
1992-10-01 00:00:00pages
703-8issue
4eissn
0213-3911issn
1699-5848journal_volume
7pub_type
杂志文章abstract：:Detailed characterization of the subdermal model is a significant tool for better understanding of calcification mechanisms occurring in heart valves. In previous ultrastructural investigation on six-week-implantated aortic valve leaflets, modified pre-embedding glutaraldehyde-cuprolinic-blue reactions (GA-CB) enabled...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-22.261
更新日期：2007-03-01 00:00:00
abstract：:Immunocytochemical demonstration of metallothionein (MT) has been reported as a useful prognostic tool in human breast cancer. The aim of this study was to determine the immunohistochemical location of MT in canine mammary tumours and its possible correlation with the morphologic characteristics of these tumours. Surg...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-14.51
更新日期：1999-01-01 00:00:00
abstract：:Pax genes play a pivotal role in development of the vertebrate visual system. Pax6 is the master control gene for eye development: ectopic expression of Pax6 in Xenopus laevis and Drosphila melanogaster leads to the formation of differentiated eyes on the legs or wings. Pax6 is involved in formation of ganglion cells ...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-16.239
更新日期：2001-01-01 00:00:00
abstract：:This study evidences the presence of primordial germ cells, in tissue squash preparations and sections from hematological malignancies. Primordial germ cells were identified by their morphology, the intense PAS, PAS-D reaction and presence of calcium-activated neutral proteinase. Primordial germ cells gave rise to nuc...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:A comparative histochemical and morphometric study in two groups of homologous muscles from different tetrapods (rat, pigeon, lizard and frog) was performed. On the basis of their fiber diameters and oxidative enzyme activities, an initial correlation between fiber types of all animals is observed, although in the liz...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：:Spermatogenesis is under the control of a complex endocrine and paracrine system, including estrogen receptor (ER) signaling. In many target cells, ER promotes the transcription of c-fos and other proto-oncogenes to regulate cell growth and differentiation. Thus, in this study we evaluated the expression of the proto-...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-24.1515
更新日期：2009-12-01 00:00:00
abstract：:HNK-1 positive (HNK-1+) cells in human peripheral blood and lymph nodes were comparatively analysed by means of immunohistochemistry and immunoelectron microscopy. In peripheral blood, the HNK-1+ cells were grouped into large granular lymphocytes (LGLs), small lymphocytes and intermediate forms, all of which had many ...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：:Soft dental tissues have been identified as easily accessible sources of multipotent postnatal stem cells. Dental stem cells are mesenchymal stem cells (MSC) capable of differentiating into at least three distinct cell lineages: osteo/odontogenic, adipogenic and neurogenic. They express various markers including those...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-29.699
更新日期：2014-06-01 00:00:00
abstract：AIMS:The expression patterns of TGFB signaling proteins, such as TGFB1/2, TGFBR1(ALK5), TGFBR2, SMAD1/2/3, SMAD2/3, SMAD4, SMAD7, and of downstream targets of TGFB signaling, CDKN1A (p21CIP1), CDKN1B (p27KIP1), MYC, CDC25A, TP53, and RELA (p65NF-kB) were investigated in gastric carcinomas and other gastric lesions. ME...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-23.1439
更新日期：2008-12-01 00:00:00
abstract：:Sixty male Wistar rats were used for this experiment and assigned at random to the control group or to the stimulation method. Control rats show cerebral asymmetry with right bias at the frontal and occipital lobes. In the case of stimulated rats the differences from the occipital zone increase while those from the fr...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：:Despite years of research into its pathobiology and continuing clinical trials for novel therapies, the prognosis for patients with glioblastoma (GBM) remains dismal. An important obstacle against treatment efficacy may be a high degree of intra- and inter-tumoral heterogeneity within GBMs, which may be caused by the ...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-11-695
更新日期：2016-03-01 00:00:00
abstract：:Actin microfilaments and microtubules are important cytoskeletal proteins that regulate endothelial repair through alterations in cell shape and through regulation of cell migration following wounding of the endothelium. Upstream pathways have been identified in the regulation of actin and microtubule organization, es...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-18.879
更新日期：2003-07-01 00:00:00
abstract：:The presence of Cajal-Retzius cells in the adult human prefrontal and visual cortices has been demonstrated with calcium binding protein immunocytochemistry and NADPH-diaphorase histochemistry. These cells expressed parvalbumin, calbindin and calretinin calcium binding proteins and displayed NADPH-diaphorase enzyme ac...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-14.487
更新日期：1999-04-01 00:00:00
abstract：:Primary perivascular epithelioid cell tumor (PEComa) of the liver is a very rare example of an emerging family of hepatic PEC tumors. Only few cases have been described so far. We report the case of a large but benign hepatic PEComa in a 53-year-old man without signs of tuberous sclerosis. In contrast to recently desc...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-23.1185
更新日期：2008-10-01 00:00:00
abstract：:The aims of the present study were to apply the AMG technique for localization of mercury at the light and electron microscopic level in the ovary of crucian carp after exposure to mercuric chloride and to find out if this heavy metal induces expression of caspase-3. Depending on the stage of ovarian follicle developm...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-24.141
更新日期：2009-02-01 00:00:00
abstract：:The aim of this study was to demonstrate the morphology and matrix synthesis of embryonic rat liver cells (day 18 of gestation) in organoid cultures (high density cultures) with electron microscopic and immunomorphological techniques. For this purpose the cells of embryonic rat livers were isolated enzymatically and g...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD), however, specific treatment for DN has not yet been elucidated. Therefore, it is critically important to understand the molecular mechanism underlying DN to develop cause-related therapeutic strategy. To date, various factors such as hemodyn...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-11-777
更新日期：2016-10-01 00:00:00
abstract：:This report describes the gross, histopathological, immunocytochemical and electron microscopic findings in a cat with systemic cryptococcosis and feline immunodeficiency virus (FIV) infection. Lymphadenopathy and cloudiness of leptomeninges were the major gross findings. Numerous cryptococcal yeasts were found in lym...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:Dysadherin, a cancer associated cell membrane glycoprotein, has been reported to downregulate E-cadherin. Aberrant expression of E-cadherin has been associated with the development of metastases in patients with cancer. Even though the expression of dysadherin and E-cadherin has been studied in primary non-small cell ...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-25.1257
更新日期：2010-10-01 00:00:00
abstract：:The ultrastructure of the atrial myocardium in the monkey (Macaca fascicularis) was studied after bilateral cervical vagotomy and survival times of 100, 175 and 367 days. Changes were observed in the nucleus and the cytoplasm of the myocyte. Sequestered within the nuclei of the affected myocytes were cytoplasmic organ...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：:Epidemiologic studies have suggested that elderly patients who consumed diets rich in antioxidants throughout their lives are less likely to be afflicted with age-related macular degeneration (AMD). This led to the Age-Related Eye Disease Study, which showed that supplements containing antioxidant vitamins and zinc re...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-22.1301
更新日期：2007-12-01 00:00:00
abstract：:The characteristics and distribution pattern of retinal afferent terminals making synaptic contacts on narrow field vertical neurons in the stratum griseum superficiale of the rabbit superior colliculus were studied using the Golgi-gold substitution technique in combination with either autoradiographic or degenerative...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Synaptotagmin 7 (SYT7) is a component of the synaptotagmin family, which is essential in many physiological and pathological processes. In this study, we aimed to investigate the role of SYT7 in osteosarcoma. METHODS:We defined the expression levels of SYT7 in osteosarcoma tissues and para-sarcoma tissues b...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-18-174
更新日期：2020-03-01 00:00:00
abstract：:One hundred and eleven pituitary glands of patients (93 males, 18 females; mean age 32 years, 5 months) who died of fully developed AIDS or ARC were examined under light microscopy with the aid of immunohistochemistry. On post mortem (p.m.) examination a wide series of multiorgan alterations was noticed. Microscopical...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:A proportion of anaplastic large cell tumours is difficult to classify on sections of routinely processed, paraffin-embedded tissue. Differentiation into large cell lymphoma, carcinoma, melanoma or sarcoma is important in order to assess prognosis and proper treatment. Although the use of immunohistochemistry has been...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：:Sialoderivatives expressed in the rabbit oviduct under hormonal treatment have been investigated in situ by lectin histochemistry with a view to specifying further regional and temporal specializations which enable ampulla and isthmus to play distinct roles in the reproductive events. Application of MAL II and SNA lec...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-19.1175
更新日期：2004-10-01 00:00:00
abstract：:Programmed death-ligand 1 (PD-L1) is an inhibitory transmembrane protein that can prevent autoimmune response. Upregulated PD-L1 serves as a predictive biomarker for patients who may respond well to immune checkpoint therapies. However, variable associations of PD-L1 level with prognoses have been reported. In this st...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-18-272
更新日期：2020-10-28 00:00:00
abstract：:The influence of He-Ne laser radiation on the formation of new blood vessels in the bone marrow compartment of a regenerating area of the mid-cortical diaphysis of the tibiae of young adult rats was studied. A small hole was surgically made with a dentistry burr in the tibia and the injured area received a daily laser...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-19.43
更新日期：2004-01-01 00:00:00
abstract：:Primary cultured human salivary gland cells were transfected with ori-defective mutant DNA of SV40. Following 2-3 weeks of transfection, slowly expanding colonies consisting of small compact cells emerged, while mock-transfected cells did not grow any more and eventually entered crisis, followed by cell death. Using l...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：
更新日期：1994-10-01 00:00:00
abstract：:The effects of diethylstilbestrol (DES) and of long-acting somatostatin analog, octreotide (SMS) on the rat anterior pituitary microvasculature have been studied by means of computer-assisted image analysis. Additionally, the effects of DES and SMS on prolactin secretion and anterior pituitary cell proliferation have ...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
