Abstract:
:Primary perivascular epithelioid cell tumor (PEComa) of the liver is a very rare example of an emerging family of hepatic PEC tumors. Only few cases have been described so far. We report the case of a large but benign hepatic PEComa in a 53-year-old man without signs of tuberous sclerosis. In contrast to recently described PEC-derived liver tumors in children and young adults, this neoplasm was not related to the hepatic ligaments but had developed deeply within the liver substance. The neoplastic cells displayed the complete phenotype typical for PEComas, i.e. reactivity for several melanoma markers and for smooth muscle actin. The unique relationship of myoid tumor cells to the adventitia of blood vessels prompted us, in comparison with published findings obtained with angiomyolipomas, to comment on the possible origin of the still enigmatic perivascular epithelioid cells.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Zimmermann A,von der Brelie C,Berger B,Kappeler A,Candinas Ddoi
10.14670/HH-23.1185subject
Has Abstractpub_date
2008-10-01 00:00:00pages
1185-93issue
10eissn
0213-3911issn
1699-5848journal_volume
23pub_type
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