Three types of liver cell dysplasia (LCD) in small cirrhotic nodules are distinguishable by karyometry and PCNA labelling, and their features resemble distinct grades of hepatocellular carcinoma.

abstract：:Sialoderivatives expressed in the rabbit oviduct under hormonal treatment have been investigated in situ by lectin histochemistry with a view to specifying further regional and temporal specializations which enable ampulla and isthmus to play distinct roles in the reproductive events. Application of MAL II and SNA lec...

journal_title：Histology and histopathology

authors： Gabrielli MG,Bondi AM,Materazzi G,Menghi G

更新日期：2004-10-01 00:00:00

abstract：:Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD), however, specific treatment for DN has not yet been elucidated. Therefore, it is critically important to understand the molecular mechanism underlying DN to develop cause-related therapeutic strategy. To date, various factors such as hemodyn...

journal_title：Histology and histopathology

authors： Kawanami D,Matoba K,Utsunomiya K

更新日期：2016-10-01 00:00:00

abstract：:Tumorigenesis correlates with hypermethylation of tumor suppressors and hypomethylation of oncogenes. DNA methyltransferases (DNMTs) catalyze DNA methylation, and mutations and aberrant expression in DNMT genes are found in multiple human tumors. The discovery of the DNA demethylation function of TET proteins has open...

journal_title：Histology and histopathology

authors： Wu YC,Ling ZQ

更新日期：2014-08-01 00:00:00

abstract：:The bronchial-associated lymphoid tissue (BALT) is a lymphoepithelial organ, related to the immune defence of the lung and to alveolar clearance, which changes size in certain states of disease. Changes in the size of BALT were quantified and compared, and Spearman's test was used to test the relation with the bronchi...

journal_title：Histology and histopathology

authors： Escolar Castellón JD,Escolar Castellón A,Roche Roche PA,Miñana Amada C

更新日期：1992-07-01 00:00:00

abstract：:Studies with scanning electron microscopy in the normal human sulcular epithelium are scarce, and no precise information exists about cell surface patterns along the epithelium, the frequencies of these patterns, or possible regional differences within the mouth. In five periodontal biopsy specimens each from the ante...

journal_title：Histology and histopathology

authors： Sánchez-Quevedo MC,Moreu G,Campos A,García JM,González-Jaranay M

更新日期：1994-01-01 00:00:00

abstract：:The renin-angiotensin system (RAS) and tubuloglomerular feedback (TGF) are central to the maintenance of blood pressure and body fluid composition. Renin, NO synthase-1 (NOS-1), and cyclooxygenase-2 (COX-2) are key regulators of the RAS and TGF. In the present study, to investigate species-specific differences in the ...

journal_title：Histology and histopathology

authors： Ichii O,Yabuki A,Ojima T,Matsumoto M,Taniguchi K,Suzuki S

更新日期：2008-02-01 00:00:00

abstract：:Renal oncocytosis is a recently established disease entity characterized by numerous oncocytic tumors and diffuse involvement of oncocytic changes in renal parenchymal epithelia. In this article, we review this disease with a focus on its clinical and pathobiological aspects. Clinically, renal oncocytosis may occur in...

journal_title：Histology and histopathology

authors： Kuroda N,Tanaka A,Ohe C,Mikami S,Nagashima Y,Sasaki T,Inoue K,Hes O,Michal M,Brunelli M,Martignoni G

更新日期：2012-11-01 00:00:00

abstract：:Sulfur dioxide (SO₂) is a toxic gas and air pollutant. The toxic effects of SO₂ have been extensively studied. Oxidative damage due to SO₂ can occur in multiple organs. Inhaled SO₂ can also cause chromosomal aberrations, DNA damage and gene mutations in mammals. However, SO₂ can also be generated from the sulfur-conta...

journal_title：Histology and histopathology

authors： Wang XB,Cui H,Liu X,Du JB

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Protein tyrosine kinase 7 (PTK7) is a member of receptor protein tyrosine kinase-like molecules, which is involved in tumorigenesis. However, the association between PTK7 expression and its pathological significance in survival prognosis remains under investigation. The purpose of this meta-analysis is to cl...

journal_title：Histology and histopathology

authors： Chen G,Qi S,Yang X,Chen W

更新日期：2018-04-01 00:00:00

abstract：:We describe a new technique, decalcification by perfusion, for the softening of bony tissue. The blood circulatory system was perfused in 16 rats via a cannula through the left heart ventricle with a fixative followed by New Decalc (an acidic demineralizer) for 30-240 minutes. Perfusion decalcification for 120 minutes...

journal_title：Histology and histopathology

authors： Nilsson M,Hellström S,Albiin N

更新日期：1991-07-01 00:00:00

abstract：:Glucocorticoids play a major role in attenuation of the inflammatory response and they are useful in the primary combination chemotherapy of breast cancer, since in vitro studies have demonstrated an antiproliferative effect in human breast cancer cells. In contrast, it was recently shown that glucocorticoids protect ...

journal_title：Histology and histopathology

authors： Conde I,Paniagua R,Fraile B,Lucio J,Arenas MI

更新日期：2008-01-01 00:00:00

abstract：:Mitochondrial transcription factor A (mtTFA) plays a crucial role in both the transcription and maintenance of mitochondrial DNA. A high expression of mtTFA has been demonstrated in several solid tumors, and is closely associated with cancer cell survival/apoptosis and growth. However, its expression pattern in pancre...

journal_title：Histology and histopathology

authors： Kimura T,Kitada S,Uramoto H,Zhi L,Kawatsu Y,Takeda T,Horie S,Nabeshima A,Noguchi H,Sasaguri Y,Izumi H,Kohno K,Yamada S

更新日期：2015-02-01 00:00:00

abstract：:Src, a 60 kDa non-receptor tyrosine kinase, is the product of normal c-src of the human genome and member of the Src protein tyrosine kinases family (SFK). As described by Martin and Rous, a genetic recombination between c-src and the RSV oncogene of Rous sarcoma virus results in a modified Src protein, with increased...

journal_title：Histology and histopathology

authors： Chatzizacharias NA,Kouraklis GP,Giaginis CT,Theocharis SE

更新日期：2012-06-01 00:00:00

abstract：:Glaucoma is a neurodegenerative disease characterized by progressive loss of retinal ganglion cell axons and their cell bodies in the retina. Elevated intraocular pressure (IOP) is considered to be the major risk factor associated with the development of this neuropathy. Randomized controlled clinical trials have demo...

journal_title：Histology and histopathology

authors： García-Campos J,Villena A,Díaz F,Vidal L,Moreno M,Pérez de Vargas I

更新日期：2007-12-01 00:00:00

abstract：:In the present study, morphological changes of the exocrine pancreas in rats after pancreatic duct ligation were examined with light microscopy (hematoxylin-eosin, TUNEL, and PCNA staining) and scanning electron microscopy in order to elucidate the effects of increased pancreatic duct pressure. On the fifth day after ...

journal_title：Histology and histopathology

authors： Hamamoto N,Ashizawa N,Niigaki M,Kaji T,Katsube T,Endoh H,Watanabe M,Sumi S,Kinoshita Y

更新日期：2002-10-01 00:00:00

abstract：:Six 4 month-old beagles were inoculated with Leishmania donovani infantum, three of them intraperitoneally (Group A) and the other three intravenously (Group B). The animals from Group A were killed 109, 433 and 592 days after inoculation and animals from Group B 109, 171 and 334 after inoculation. The liver of each o...

journal_title：Histology and histopathology

authors： González JL,Rollán E,Novoa C,Castaño M

更新日期：1988-10-01 00:00:00

abstract：:In order to analyze the incidence and prevalence of Human Papillomavirus (HPV) in penile carcinoma, we studied 49 patients with penile carcinoma. Formalin-fixed, paraffin-embedded tissue samples were collected from 64 samples of penile carcinoma from the Hospital General Universitario (Albacete, Spain). Cases were his...

journal_title：Histology and histopathology

authors： Pascual A,Pariente M,Godínez JM,Sánchez-Prieto R,Atienzar M,Segura M,Poblet E

更新日期：2007-02-01 00:00:00

abstract：:There is scarce information on the possible effects of chronic exposure to mercury on skeletal muscle. Dental personnel are frequently exposed to inhalation of metallic mercury vapours. The skeletal muscle of five technicians and one dentist (females, age 36-55) was studied. All of them presented symptoms of chronic m...

journal_title：Histology and histopathology

authors： Nadorfy-López E,Torres SH,Finol H,Méndez M,Bello B

更新日期：2000-07-01 00:00:00

abstract：:The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of ligand-activated transcription factors, which plays crucial role in bile acid, cholesterol, lipid and glucose metabolism, as well as in the development of atherosclerosis, intestinal bacterial growth and liver regeneration. FXR is also i...

journal_title：Histology and histopathology

authors： Koutsounas I,Giaginis C,Theocharis S

更新日期：2012-07-01 00:00:00

abstract：:The aim of this study was to examine the effects of timolol in an experimental model of elevated intraocular pressure (IOP). Three episcleral veins of rats with normal IOP were cauterized. Three months later we examined the effects on anterograde axonal transport from the retinal ganglion cells (RGCs) to the superior ...

journal_title：Histology and histopathology

authors： Díaz F,Villena A,Moreno M,Vidal L,Parrado C,García-Campos J,de Vargas IP

更新日期：2005-10-01 00:00:00

abstract：:Spermatogenesis is under the control of a complex endocrine and paracrine system, including estrogen receptor (ER) signaling. In many target cells, ER promotes the transcription of c-fos and other proto-oncogenes to regulate cell growth and differentiation. Thus, in this study we evaluated the expression of the proto-...

journal_title：Histology and histopathology

authors： Araújo FC,Oliveira CA,Reis AB,Del Puerto HL,Martins AS,Reis FM

更新日期：2009-12-01 00:00:00

abstract：:Bacillus subtilis has been used as a classic model to study biofilm formation and sporulation process. Colonies of wild-type strains usually have a complex external morphology, but the details of their internal architecture are still undisclosed. Since bacterial biofilms fulfill the criteria to be considered tissues, ...

journal_title：Histology and histopathology

authors： Gómez-Aguado F,Corcuera MT,Gómez-Lus ML,de la Parte MA,Ramos C,García-Rey C,Alonso MJ,Prieto J

更新日期：2013-10-01 00:00:00

abstract：:The adrenal glands of lower vertebrates display a notable intermingling between steroidogenic and chromaffin tissues, which increases from Pisces to Aves. As in mammals, adrenal chromaffin cells contain and release, in addition to catecholamines, serotonin and several peptides, which may affect the secretory activity ...

journal_title：Histology and histopathology

authors： Mazzocchi G,Gottardo G,Nussdorfer GG

更新日期：1998-01-01 00:00:00

abstract：:Thyroid hormones (TH) stimulate oxidative metabolism in many tissues in the body, but testis is not one of them. Therefore, in this sense, testis is not considered as a target organ for TH. However, recent findings clearly show that TH have significant functions on the testis in general, and Leydig cells in particular...

journal_title：Histology and histopathology

authors： Mendis-Handagama SM,Ariyaratne HB

更新日期：2004-07-01 00:00:00

abstract：:Melanocytes characterized by their tyrosinase activity, melanosomes and dendrites locate in the basal layer of epidermis and hair bulb in the skin of mice. Melanocytes differentiate from undifferentiated melanoblasts derived from embryonic neural crest. Melanocyte-stimulating hormone plays an important role in the reg...

journal_title：Histology and histopathology

authors： Hirobe T

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Synaptotagmin 7 (SYT7) is a component of the synaptotagmin family, which is essential in many physiological and pathological processes. In this study, we aimed to investigate the role of SYT7 in osteosarcoma. METHODS:We defined the expression levels of SYT7 in osteosarcoma tissues and para-sarcoma tissues b...

journal_title：Histology and histopathology

authors： Wu Z,Sun Z,Huang R,Zang D,Wang C,Yan X,Yan W

更新日期：2020-03-01 00:00:00

abstract：:Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. In addition, spectrins have been implicated in TGF-beta signaling. The aim of the present study was to analyze the expression and localization of beta...

journal_title：Histology and histopathology

authors： Jiang X,Gillen S,Esposito I,Giese NA,Michalski CW,Friess H,Kleeff J

更新日期：2010-12-01 00:00:00

abstract：:The coexistence of serotonin and cholecystokinin was studied in foetal sheep lungs at pseudoglandular stage of development by light microscopic immunohistochemistry. The coexistence was examined by staining consecutive sections with the different antibodies. Serotonin and cholecystokinin immunoreactivity was found wit...

journal_title：Histology and histopathology

authors： Balaguer L,Romano J,Ruiz-Pesini P

更新日期：1994-01-01 00:00:00

abstract：:Primary cultured human salivary gland cells were transfected with ori-defective mutant DNA of SV40. Following 2-3 weeks of transfection, slowly expanding colonies consisting of small compact cells emerged, while mock-transfected cells did not grow any more and eventually entered crisis, followed by cell death. Using l...

journal_title：Histology and histopathology

authors： Azuma M,Sato M

更新日期：1994-10-01 00:00:00

abstract：:One hundred and eleven pituitary glands of patients (93 males, 18 females; mean age 32 years, 5 months) who died of fully developed AIDS or ARC were examined under light microscopy with the aid of immunohistochemistry. On post mortem (p.m.) examination a wide series of multiorgan alterations was noticed. Microscopical...

journal_title：Histology and histopathology

authors： Mosca L,Costanzi G,Antonacci C,Boldorini R,Carboni N,Cristina S,Liverani C,Parravicini C,Pirolo A,Vago L

更新日期：1992-04-01 00:00:00