Coexistence of serotonin and cholecystokinin in paraneurons of the foetal sheep lung.


:The coexistence of serotonin and cholecystokinin was studied in foetal sheep lungs at pseudoglandular stage of development by light microscopic immunohistochemistry. The coexistence was examined by staining consecutive sections with the different antibodies. Serotonin and cholecystokinin immunoreactivity was found within consecutive sections of most bronchopulmonary neuroepithelial bodies and in consecutive sections of the same intrapulmonary autonomic ganglia.


Histol Histopathol


Balaguer L,Romano J,Ruiz-Pesini P


Has Abstract


1994-01-01 00:00:00












  • Less gelatinases is associated with apolipoprotein E accumulation in glomerulosclerosis rats.

    abstract:BACKGROUND:Gelatinases include matrix metalloproteinase-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9). The abnormal expressions of gelatinases are implicated in the pathogenesis of extracellular matrix (ECM) accumulation. Apolipo-protein E (apoE) is an important plasma protein in cholesterol homeostasis and plays a ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Zhou TB,Qin YH,Lei FY,Su LN,Zhao YJ,Huang WF

    更新日期:2012-02-01 00:00:00

  • Histopathological findings in the peritumoral edema area of human glioma.

    abstract::Peritumoral brain edema (PTBE) is considered to be one of the main biological behaviors of brain glioma. However, the histopathological features of PTBE remain imprecisely defined. We analyzed the histopathological characteristics in the PTBE area of 22 cases of glioma. Microscopically, the pre-existing basic structur...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Wang X,Liu X,Chen Y,Lin G,Mei W,Chen J,Liu Y,Lin Z,Zhang S

    更新日期:2015-09-01 00:00:00

  • Anti-platelet agents reduce morphological changes of chronic hypoxic pulmonary hypertension.

    abstract::The pathophysiologic mechanism by which chronic hypoxia causes pulmonary hypertension is unknown. If anti-platelet agents, or other pharmacologic interventions, altered the pulmonary vascular changes induced by hypoxia, information concerning the pathogenesis of the pulmonary hypertension or the potential therapeutic ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Keith IM,Will JA,Huxtable RJ,Weir K

    更新日期:1987-04-01 00:00:00

  • The distribution of corticotropin-releasing factor immunoreactive neurons and nerve fibres in the brain of Gambusia affinis and Salmo trutta.

    abstract::The study was carried out on the distribution of neurons and fibres which contain the Corticotropin releasing factor-like (CRF) immunoreactivity in the encephalon of two species of teleosts, Gambusia affinis and Salmo trutta. The peroxidase-antiperoxidase (PAP) immunocytochemical technique was employed. The present st...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Coto-Montes A,García-Fernández JM,del Brío MA,Riera P

    更新日期:1994-04-01 00:00:00

  • Fine reconstruction of the pancreatic ductular system at the onset of pancreatitis.

    abstract::The three-dimensional structure of the pancreatic ductular system (from the intercalated duct to the intercellular secretory canaliculus) is controversial and unclear. The aim of this study is to reveal the three-dimensional structure of the pancreatic ductular sysytem at the onset of pancreatitis. One day following r...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Endo H,Ashizawa N,Niigaki M,Hamamoto N,Niigaki M,Kaji T,Katsube T,Watanabe M,Naora H,Otani H,Kinoshita Y

    更新日期:2002-01-01 00:00:00

  • The glomerular distribution of laminin and fibronectin in glomerulonephritis.

    abstract::Laminin (LAM) and fibronectin (FI) are regarded as major components of the glomerular extracellular matrix. The aim of this study was to define the distribution of LAM and FI in primary glomerulonephritis (GN) and GN of systemic lupus erythematosus (SLE) and to correlate the type of glomerular disorders with possible ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Nakapoulou I,Stefanaki K,Zeis PM,Papadakis J,Boletis J,Vosnidis G,Davaris P

    更新日期:1993-07-01 00:00:00

  • Cells with morphological and immunohistochemical features of hepatic stellate cells (Ito cells) form an extralittoral (extrasinusoidal) compartment in the cirrhotic rat liver.

    abstract::Systematic studies on hepatic stellate cells and myofibroblasts have so far mainly focused on cells located in the perisinusoidal space of Disse, the so-called littoral compartment. Here, these cells play a key role for intralobular fibrogenesis and sinusoidal capillarization. However, advanced hepatic fibrosis and ci...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Zimmermann A,Zimmermann H,Fellay M,Reichen J

    更新日期:1999-07-01 00:00:00

  • Paracrine control of steroid hormone secretion by chromaffin cells in the adrenal gland of lower vertebrates.

    abstract::The adrenal glands of lower vertebrates display a notable intermingling between steroidogenic and chromaffin tissues, which increases from Pisces to Aves. As in mammals, adrenal chromaffin cells contain and release, in addition to catecholamines, serotonin and several peptides, which may affect the secretory activity ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审


    authors: Mazzocchi G,Gottardo G,Nussdorfer GG

    更新日期:1998-01-01 00:00:00

  • Immunohistochemical expression and localization of MMP-9, MMP-13, E-Cadherin and Ki-67 in road pavers' skin chronically exposed to bitumen products.

    abstract::To investigate the matrix metalloproteinase (MMP)-9, (MMP)-13, E-Cadherin and Ki-67 expressions in road pavers' skin chronically exposed to bitumen products in order to contribute to a better understanding of the earlier tissue alteration. Skin punch biopsies from 16 daily exposed workers and a control group were stud...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Loreto C,Lombardo C,Caltabiano R,Filetti V,Vitale E,Seminara D,Castorina S,Fenga C,Ledda C,Rapisarda V

    更新日期:2019-10-01 00:00:00

  • Primary papillary psammomatous adenocarcinoma of the umbilicus.

    abstract::The histological and ultrastructural features, as well as the immunoreactivity of one case of uncommon primary papillary and psammomatous adenocarcinoma of the umbilicus are studied in the present work. The observations have been undertaken in a nine-year follow-up, and have included the primitive tumour, two local re...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Hernández N,Medina V,Alvarez-Arguelles H,Gutiérrez R,Pérez-Palma J,Díaz-Flores L

    更新日期:1993-10-01 00:00:00

  • Ecophysiological responses of the seminal vesicle of Libyan jird (Meriones libycus) to the Saharan conditions: histological, morphometric and immunohistochemical analysis.

    abstract::The Libyan jird (Meriones libycus) is a nocturnal Saharan Rodent submitted to a seasonal cycle of reproduction characterized by a short active period during spring and beginning of summer, and a long phase of sexual quiescence from the end of summer until the end of winter. During this cycle, the male reproductive org...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Belhocine M,Gernigon-Spychalowicz T,Robert AM,Schoevaert D,Bennazzoug Y,Exbrayat JM

    更新日期:2007-06-01 00:00:00

  • Molecular biology of glioma tumorigenesis.

    abstract::Gliomas are the most common intracranial malignant tumors in humans, and high-grade gliomas in particular pose a unique challenge due to their propensity for proliferation and tissue invasion. Our understanding of glioma oncogenesis, proliferation, and invasion has been greatly advanced in the past 10 years as researc...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审


    authors: Ware ML,Berger MS,Binder DK

    更新日期:2003-01-01 00:00:00

  • Retinal and lenticular ultrastructure in the aestivating salamanderfish, Lepidogalaxias salamandroides (Galaxiidae, Teleostei) with special reference to a new type of photoreceptor mosaic.

    abstract::The salamanderfish, Lepidogalaxias salamandroides (Galaxiidae, Teleostei) is endemic to southwestern Australia and inhabits shallow, freshwater pools which evaporate during the hot summer months. Burrowing into the substrate in response to falling water levels allows these fish to aestivate for extended periods of tim...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Collin SP,Collin HB

    更新日期:1998-10-01 00:00:00

  • Transcriptional mRNA of BMP-2, 3, 4 and 5 in trigeminal nerve, benign and malignant peripheral nerve sheath tumors.

    abstract::The aim of our study was to document whether relationships existed among bone morphogenetic proteins (BMPs), peripheral nerve and neoplastic lesions of nerve sheath tumors. The mRNA transcriptions of BMP-2, 3, 4 and 5 in 10 cases of schwannoma, three cases of malignant schwannoma and two cases of trigeminal neuralgia ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Jin Y,Lu HB,Liong E,Lau TY,Tipoe GL

    更新日期:2001-10-01 00:00:00

  • Ultrastructural evidence in vitro of osteoclast-induced degradation of calcium phosphate ceramic by simultaneous resorption and phagocytosis mechanisms.

    abstract::Osteoclasts are physiological polykaryons specialized in the resorption of calcified tissue. In the context of the clinical use of calcium-phosphate (CaP) ceramics as bone substitutes, this study used transmission electron microscopy to investigate the in vitro mechanisms of CaP ceramic degradation by osteoclastic cel...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Heymann D,Guicheux J,Rousselle AV

    更新日期:2001-01-01 00:00:00

  • Complex and elementary histological scoring systems for articular cartilage repair.

    abstract::The repair of articular cartilage defects is increasingly moving into the focus of experimental and clinical investigations. Histological analysis is the gold standard for a valid and objective evaluation of cartilaginous repair tissue and predominantly relies on the use of established scoring systems. In the past thr...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审


    authors: Orth P,Madry H

    更新日期:2015-08-01 00:00:00

  • Ultrastructural observation on the rat supraoptic neurons following acute operative stress.

    abstract::The response of the SON to various forms of stress is well documented. However, the effect of operative stress, which is a common and important clinical event requiring the mediation of vasopressin, has largely escaped attention. The present report describes the ultrastructural changes in the neurons of the caudal (re...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Ray PK,Choudhury SR

    更新日期:1988-04-01 00:00:00

  • Induction system of neural and muscle lineage cells from bone marrow stromal cells; a new strategy for tissue reconstruction in degenerative diseases.

    abstract::Since bone marrow stromal cells (MSCs) are easily accessible both from healthy donors and patients, and can be expanded on a therapeutic scale, they have attracted attention for cell-based therapy. MSCs contribute to the protection of host tissue after transplantation by Immune modulation and trophic effect. They also...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审


    authors: Kitada M,Dezawa M

    更新日期:2009-05-01 00:00:00

  • Monoclonal antibody against histiocytosis X cells.

    abstract::Monoclonal antibody against histiocytosis X cells (HXCs) was established. The antigen was the cell membrane of HXCs from the submandibular lesion of a 63-year-old man who had been diagnosed as an adult type of histiocytosis X (HX) and whose HXCs had numerous Birbeck granules (BGs). The obtained monoclonal antibody, na...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Ishikawa M,Matsuda M,Imai Y

    更新日期:1992-07-01 00:00:00

  • MYC and BCL-2 adjusted-International Prognostic Index (A-IPI) is a better predictor of outcome than the standard IPI for patients with diffuse large B-cell lymphoma treated with R-CHOP.

    abstract::The International Prognostic Index (IPI) has been the basis for determining prognosis in patients with diffuse large B-cell lymphoma (DLBCL) for the past 20 years. The utility of the IPI must be reassessed in the era of immunochemotherapy. Seven risk factors at diagnosis were identified, and a maximum of 7 points were...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Wang J,Zhou M,Xu JY,Yang YG,Zhang QG,Zhou RF,Chen B,Ouyang J,Li C

    更新日期:2016-03-01 00:00:00

  • Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic diseases.

    abstract::HtrA1 is a secreted protein which behaves as a molecular chaperone at low temperatures and as a serine protease at high temperatures. When the placenta escapes the normal growth control mechanisms, which are present during normal pregnancy, it may develop trophoblastic diseases, such as hydatidiform mole and choriocar...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Marzioni D,Quaranta A,Lorenzi T,Morroni M,Crescimanno C,De Nictolis M,Toti P,Muzzonigro G,Baldi A,De Luca A,Castellucci M

    更新日期:2009-10-01 00:00:00

  • Time-dependent effects of maternal continuous propranolol on fetal lung development in rats.

    abstract::Previous studies have demonstrated a role for the beta-adrenergic system in the maturation of the fetal alveolar epithelium. Chronic blockade of beta-adrenergic binding sites has been shown to adversely effect physiologic and biochemical indices of fetal lung maturation. In the present study timed-pregnant female Spra...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Smith DM,Sommers SS

    更新日期:2002-04-01 00:00:00

  • The thyroid gland of Callithrix jacchus in organ culture.

    abstract::Thyroid glands from 7 marmosets (Callithrix jacchus) of different age groups (newborn, 2 weeks, 2, 7, 8 and 11 months, and 8 years) were grown as organ culture according to Trowell at the medium/air interphase for 3 to 30 days. The morphology of thyroid tissue was well preserved until the end of the culture period. Ne...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Maile S,Merker HJ

    更新日期:1995-10-01 00:00:00

  • Epidemiology and molecular biology of gastrointestinal stromal tumors (GISTs): a population-based study in the South of Switzerland, 1999-2005.

    abstract::Introduction. Gastrointestinal stromal tumors (GISTs) are characterized at the molecular level by c-kit or PDGFRA oncogene mutations. Although GISTs raised major interest in past decades, population-based studies are still rare. Materials and Methods. All GISTs diagnosed in Southern Switzerland (1999-2005) were identi...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Mazzola P,Spitale A,Banfi S,Mazzucchelli L,Frattini M,Bordoni A

    更新日期:2008-11-01 00:00:00

  • CD34+ stromal cells/fibroblasts/fibrocytes/telocytes as a tissue reserve and a principal source of mesenchymal cells. Location, morphology, function and role in pathology.

    abstract::We review the morphofunctional characteristics of CD34+ stromal fibroblastic/fibrocytic cells (CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ SFCs: A) The confusing terms applied to this cell type, often combining the prefix CD34 with numerous names, including fibroblasts, fibrocyt...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审


    authors: Díaz-Flores L,Gutiérrez R,García MP,Sáez FJ,Díaz-Flores L Jr,Valladares F,Madrid JF

    更新日期:2014-07-01 00:00:00

  • M1- and M2-macrophage polarization in thioacetamide (TAA)-induced rat liver lesions; a possible analysis for hepato-pathology.

    abstract::"Classically activated macrophages (M1)" and "alternatively activated macrophages (M2)", which appear in injured tissues, control either inflammation or remodeling. The mechanism remains unclear. To clarify the M1-/M2-macrophage polarization in acute liver injury, M1- and M2-related factors were analysed in F344 rats ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Wijesundera KK,Izawa T,Murakami H,Tennakoon AH,Golbar HM,Kato-Ichikawa C,Tanaka M,Kuwamura M,Yamate J

    更新日期:2014-04-01 00:00:00

  • Tumor heterogeneity has important consequences for personalized medicine in ovarian cancer.

    abstract::Most patients with ovarian cancers relapse, and treatment failure has often been attributed to chemoresistance in tumor cells. Emerging evidence indicates that tumor heterogeneity may play an equally important role. Although the idea of tumor heterogeneity is not new, little attention has been focused on applying it t...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审


    authors: Gui T,Cao D,Yang J,Shen K

    更新日期:2015-02-01 00:00:00

  • Circadian and seasonal cortico-medullary variations in pinealocyte nuclear size. A comparative statistical analysis.

    abstract::Circadian and seasonal variations were observed in the karyometric index of pinealocytes in the cortical and medullary regions of the distal pineal body. The study involved 70 Wistar rats over a 24-hour interval (0:6, 10:00, 14:00, 18:00, 22:00, 02:00, 06:00 h) during two natural photoluminous periods, i.e. late summe...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Cimas García C,Martínez Soriano F,Ruiz Torner A

    更新日期:1992-10-01 00:00:00

  • Collagen-platelet interaction: platelet non-integrin receptors.

    abstract::Platelet-collagen interaction is a complex event that involves ligand-receptor interaction. There are many adhesive non-integrin receptors for platelets to interact with various types of collagens. These non-integrin receptors also serve as signal transducers both from the outside of platelets to the inside and possib...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审


    authors: Chiang TM

    更新日期:1999-04-01 00:00:00

  • Smad4 expression in gastric adenoma and adenocarcinoma: frequent loss of expression in diffuse type of gastric adenocarcinoma.

    abstract::Smads are signal transducers for the members of the TGF-beta superfamily. Of these Smads, Smad4 is essential for TGF-beta signaling. The purpose of this study was to elucidate Smad4 expression and localization in 65 gastric adenomas, 49 intestinal-type and 39 diffuse type of gastric adenocarcinomas (including 12 cases...

    journal_title:Histology and histopathology

    pub_type: 杂志文章


    authors: Kim JY,Park DY,Kim GH,Choi KU,Lee CH,Huh GY,Sol MY,Song GA,Jeon TY,Kim DH,Sim MS

    更新日期:2005-04-01 00:00:00