Sulfur dioxide: foe or friend for life?

Abstract:

:Sulfur dioxide (SO₂) is a toxic gas and air pollutant. The toxic effects of SO₂ have been extensively studied. Oxidative damage due to SO₂ can occur in multiple organs. Inhaled SO₂ can also cause chromosomal aberrations, DNA damage and gene mutations in mammals. However, SO₂ can also be generated from the sulfur-containing amino acid, L-cysteine. Recent studies have shown that SO₂ has a vasorelaxant effect, and ameliorates pulmonary hypertension and vascular remodeling. SO₂ can also reduce lung injury and myocardial injury in rats. In addition, SO₂ reduces myocardial ischemia-reperfusion injury and atherosclerotic lesions. Therefore, SO₂ exerts both detrimental and protective effects in mammals. Is SO₂ a foe or friend for life?.

journal_name

Histol Histopathol

authors

Wang XB,Cui H,Liu X,Du JB

doi

10.14670/HH-11-904

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

1231-1238

issue

12

eissn

0213-3911

issn

1699-5848

pii

HH-11-904

journal_volume

32

pub_type

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