Expression of neuropeptides and their receptors in the developing retina of mammals.

abstract：:It has been commonly supposed that adult stem cells co-localize with supporting cells within specific regions or specialized microenvironment in each tissue/organ, called stem cell niche. This concept was based on the assumption that stem cells are intrinsically hierarchical in nature. However, recent data indicate th...

journal_title：Histology and histopathology

authors： Deregibus MC,Tetta C,Camussi G

更新日期：2010-03-01 00:00:00

abstract：:The presence of synaptophysin, a presynaptic Ca2+ binding glycoprotein, has been analyzed in the cochlear nucleus complex of the adult cat using an antisynaptophysin monoclonal antibody. Synaptophysin immunoreactivity was differently distributed between regions of cochlear nuclei. Terminal boutons contacting directly ...

journal_title：Histology and histopathology

authors： Gil-Loyzaga P,Bartolomé MV,Ibáñez A

更新日期：1998-04-01 00:00:00

abstract：:The pancreatic-duct system was observed during the initial stage of type 1 diabetes in C57BL/6J mice rendered diabetic with low doses of streptozocin. Light microscopy revealed that the ducts located in close proximity to islets (islet ducts) were involved in the infiltrating process: inflammatory cells extended from ...

journal_title：Histology and histopathology

authors： Papaccio G,Strate C,Linn T

更新日期：1994-07-01 00:00:00

abstract：:Transforming growth factor-β (TGF-β) is a key regulator of extracellular matrix (ECM), and may mediate the development of glomerulosclerosis with accumulation of mesangial matrix. Mesangial cells secrete TGF-β in response to common in vitro fibrogenic stimuli. Yet mesangial immunostaining for active TGF-β1 is frequent...

journal_title：Histology and histopathology

authors： Lee HS

更新日期：2012-09-01 00:00:00

abstract：:The study investigated the link between the potentially nephrotoxic levels of aluminium ingested in the natural diet of eucalypt leaves by koalas in the Adelaide Hills, South Australia, and the high incidence of renal failure in koalas within this habitat. Routine histology of kidney specimens revealed no pathologies ...

journal_title：Histology and histopathology

authors： Haynes JI,Askew MJ,Leigh C

更新日期：2004-07-01 00:00:00

abstract：:The epicardium is the outer mesothelial layer of the heart. It covers the myocardium and plays important roles in both heart development and regeneration. It is derived from the proepicardium (PE), groups of cells that emerges at early developmental stages from the dorsal pericardial layer (DP) close to the atrio-vent...

journal_title：Histology and histopathology

authors： Andrés-Delgado L,Galardi-Castilla M,Mercader N,Santamaría L

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND RESULTS:Embryos from diabetic mice exhibit several forms of neural tube defects, including non-closure of the neural tube. In the present study, embryos collected at embryonic day 11.5 from diabetic pregnancies displayed open neural tube with architectural disruption of the surrounding tissues. The perce...

journal_title：Histology and histopathology

authors： Loh WT,Dheen ST,Jiang B,Kumar SD,Tay SS

更新日期：2011-08-01 00:00:00

abstract：:F10, a subline of the B16 mouse melanoma cell line, is itself the parent of the more metastatic BL6 line. BL6 cells differ from F10 cells by an alteration of the gene encoding the B56gamma regulatory subunit of protein phosphatase 2A (PP2A), which results in mRNA encoding a truncated variant of the subunit (deltagamma...

journal_title：Histology and histopathology

authors： Koma YI,Ito A,Watabe K,Kimura SH,Kitamura Y

更新日期：2004-04-01 00:00:00

abstract：:25 neuronal tumours with a panel of antibodies were studied and it was found that vimentin was present in 15 tumours. It was also found in a few cells within rosettes. PGP 9.5 showed a somatic pattern of staining with nuclear and perinuclear positivity in 23. Neurofilament reactivity was found in 14. Retinal S-antigen...

journal_title：Histology and histopathology

authors： Cruz-Sánchez FF,Rossi ML,Rodríguez-Prados S,Cusi V,Coakham HB

更新日期：1991-10-01 00:00:00

abstract：:Histochemical distribution of glycoproteins, carbohydrates and proteins rich in different amino acids were studied using histological and histochemical procedures, in Senegal sole, Solea senegalensis (Kaup, 1858) larvae from hatching until day 15. Glycogen, proteins and glycoproteins were detected in the yolk-sac of t...

journal_title：Histology and histopathology

authors： Sarasquete C,González de Canales ML,Arellano JM,Muñoz-Cueto JA,Ribeiro L,Dinis MT

更新日期：1996-10-01 00:00:00

abstract：:Macrophages play important roles in host defense mechanisms. In the brain, besides microglial cells, meningeal macrophages are present. However, the pathobiological characteristics of meningeal macrophages in rats remain to be investigated. In normal meninx, immunohistochemically, macrophages reacting to CD163 (macrop...

journal_title：Histology and histopathology

authors： Yamate J,Ishimine S,Izawa T,Kumagai D,Kuwamura M

更新日期：2009-01-01 00:00:00

abstract：:Spermatogenesis is under the control of a complex endocrine and paracrine system, including estrogen receptor (ER) signaling. In many target cells, ER promotes the transcription of c-fos and other proto-oncogenes to regulate cell growth and differentiation. Thus, in this study we evaluated the expression of the proto-...

journal_title：Histology and histopathology

authors： Araújo FC,Oliveira CA,Reis AB,Del Puerto HL,Martins AS,Reis FM

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Protein tyrosine kinase 7 (PTK7) is a member of receptor protein tyrosine kinase-like molecules, which is involved in tumorigenesis. However, the association between PTK7 expression and its pathological significance in survival prognosis remains under investigation. The purpose of this meta-analysis is to cl...

journal_title：Histology and histopathology

authors： Chen G,Qi S,Yang X,Chen W

更新日期：2018-04-01 00:00:00

abstract：:The main role of growth arrest and DNA damage-inducible (GADD) genes is to block proliferation at G1 and G2 checkpoints in response to DNA damage. The goal of this study was to examine the expression of GADD genes in primary melanomas with respect to prognosis. GADD34 was found in 73% of the primary melanomas investig...

journal_title：Histology and histopathology

authors： Korabiowska M,Cordon-Cardo C,Betke H,Schlott T,Kotthaus M,Stachura J,Brinck U

更新日期：2002-01-01 00:00:00

abstract：:Cyclin A, cyclin E, BUBR1, MAD2 and Aurora A are all cell-cycle regulatory proteins and have been proven to play crucial roles in carcinogenesis. However, their expression patterns in invasive ductal breast carcinoma (IDBC) are controversial and unclear. In this study, we examined the expression status of these candid...

journal_title：Histology and histopathology

authors： Du J,Du Q,Zhang Y,Sajdik C,Ruan Y,Tian XX,Fang WG

更新日期：2011-06-01 00:00:00

abstract：:The nerve fiber distribution in the epidermis of the hairless rat skin was studied light microscopically by means of zinc iodide-osmium tetroxide staining. Two different morphological types of free nerve fiber endings could be detected: clusters of relatively thick nerve fibers stretched up through the spinous layer u...

journal_title：Histology and histopathology

authors： Müller T

更新日期：2000-04-01 00:00:00

abstract：:Chorioamnionitis and preeclampsia account for the majority of preterm births worldwide. Thus far, adequate methods for early detection or prevention of these diseases are lacking. In preeclampsia, accelerated villous maturation is believed to compensate placental insufficiency. However, little is known about the effec...

journal_title：Histology and histopathology

authors： Vangrieken P,Vanterpool SF,van Schooten FJ,Al-Nasiry S,Andriessen P,Degreef E,Alfer J,Kramer BW,von Rango U

更新日期：2020-08-01 00:00:00

abstract：:Dysadherin, a cancer associated cell membrane glycoprotein, has been reported to downregulate E-cadherin. Aberrant expression of E-cadherin has been associated with the development of metastases in patients with cancer. Even though the expression of dysadherin and E-cadherin has been studied in primary non-small cell ...

journal_title：Histology and histopathology

authors： Mitselou A,Batistatou A,Nakanishi Y,Hirohashi S,Vougiouklakis T,Charalabopoulos K

更新日期：2010-10-01 00:00:00

abstract：:Thrombospondin-1 (TSP-1) is a matrix protein implicated in mechanisms of wound healing. TSP-1 contains the sequence cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) that has been shown to function primarily as a cell adhesion domain. Our laboratory has isolated a novel receptor specific for the CSVTCG adhesi...

journal_title：Histology and histopathology

authors： Roth JJ,Buckmire MA,Rolandelli RH,Granick MS,Tuszynski GP

更新日期：1998-10-01 00:00:00

abstract：:The anti-oxidant food additive, butylated hydroxytoluene (BHT), was fed to Sprague-Dawley rats at three concentrations: 0.2%, 0.4% and 0.8% for periods of 6, 12, 18 and 24 weeks, and the results were compared with corresponding groups treated with a potent carcinogen, 7,12-dimethylbenz[a]anthracene (DMBA) groups, with...

journal_title：Histology and histopathology

authors： Safer AM,al-Nughamish AJ

更新日期：1999-04-01 00:00:00

abstract：:Chaperone-mediated autophagy (CMA), a selective form of autophagy, where cellular proteins with KFERQ-like motif are targeted to the lysosome for degradation, is necessary to maintain cellular homeostasis. The role of CMA in neurodegenerative diseases has been extensively studied in the past decades, with defects in t...

journal_title：Histology and histopathology

authors： Hou T,Fan Y,Dan W,Liu B,Wang Z,Zeng J,Li L

更新日期：2020-07-01 00:00:00

abstract：:Erythema dyschromicum perstans (EDP) and vitiligo are two cutaneous pigmentary dermatoses of unknown etiology. In the present study, the leukocyte infiltrates in the affected skin of EDP and vitiligo patients were studied using the avidin-biotin (ABC) immunoperoxidase technique and monoclonal antibodies which recognis...

journal_title：Histology and histopathology

authors： Gross A,Tapia FJ,Mosca W,Perez RM,Briceño L,Henriquez JJ,Convit J

更新日期：1987-07-01 00:00:00

abstract：:Within the last few years, advances have been made regarding perivascular nerves and the endothelium of the vascular system, both potentially important in the understanding of the mechanisms of local control of blood flow. Endothelin-1 (ET-1) has been identified in rat cerebrovascular nerves, neuropeptide Y (NPY) has ...

journal_title：Histology and histopathology

authors： Loesch A

更新日期：2002-04-01 00:00:00

abstract：:High mobility group box 1 protein (HMGB1) is a non-histone chromosomal protein which is highly conserved, ubiquitous, and widely distributed. HMGB1 has multiple functions in the nucleus, including the maintenance of nucleosome structure, the regulation of gene transcription, and involvement in DNA recombination. HMBG1...

journal_title：Histology and histopathology

authors： Umahara T,Uchihara T,Koyama S,Hashimoto T,Akimoto J,Haraoka J,Iwamoto T

更新日期：2014-02-01 00:00:00

abstract：:Autoimmune dry eye (Sjögren's syndrome, SS) is a chronic systemic disease characterized by salivary and lacrimal gland inflammation and tissue damage leading to keratoconjunctivitis sicca and xerostomia. In this review attention has been devoted to the cause of the development of oxidative injuries of the ocular surfa...

journal_title：Histology and histopathology

authors： Cejková J,Ardan T,Cejka C,Malec J,Jirsová K,Filipec M,Ruzicková E,Dotrelová D,Brunová B

更新日期：2009-10-01 00:00:00

abstract：:Current data on the influence of neuropeptides on the growth, structure and function of cells comprising the hypothalamo-pituitary-adrenal axis were presented and discussed. The action of vasopressin, oxytocin, neurotensin, bombesin, neuropeptide Y, substance P and VIP have been evaluated. The hypothesis has been intr...

journal_title：Histology and histopathology

authors： Malendowicz LK

更新日期：1993-01-01 00:00:00

abstract：:Glucose uptake and metabolism are essential for proliferation and survival of cells, and are supposed to be enhanced in actively proliferating cell systems such as embryonic and cancer tissues. Glucose uptake is usually carried out through glucose transporters. In the developing fetal lung, metabolism of glucose is th...

journal_title：Histology and histopathology

authors： Ito T,Noguchi Y,Udaka N,Kitamura H,Satoh S

更新日期：1999-07-01 00:00:00

abstract：:A current concern about the biological effects of electromagnetic fields (EMF) is increasing with the wide spread use of X-band microwaves (MW, 8-10 GHz range). Gigahertz transverse electromagnetic (GTEM) field flat transmission lines are currently being used for experimental exposure of biological samples to high fre...

journal_title：Histology and histopathology

authors： Pérez-Bruzón RN,Del Moral A,Pérez-Castejón C,Llorente M,Vera A,Azanza MJ

更新日期：2011-09-01 00:00:00

abstract：:Programmed death-ligand 1 (PD-L1) is an inhibitory transmembrane protein that can prevent autoimmune response. Upregulated PD-L1 serves as a predictive biomarker for patients who may respond well to immune checkpoint therapies. However, variable associations of PD-L1 level with prognoses have been reported. In this st...

journal_title：Histology and histopathology

authors： Su BC,Ting CH,Lee KY,Wu SM,Feng PH,Chan YF,Chen JY

更新日期：2020-10-28 00:00:00

abstract：:Snake-like chromatin (SLC) is a nuclear alteration occurring under various pathological conditions and in different tissues. The aim of this study was the morphological and immunocytochemical characterization of SLC-positive conjunctival epithelial cells from keratoconjunctivitis sicca (KCS) patients. Impression cytol...

journal_title：Histology and histopathology

authors： Jirsova K,Juklova K,Vesela V,Filipec M

更新日期：2006-04-01 00:00:00