Cell proliferation and apoptosis in stromal corneal dystrophies.

abstract：:To date, no detailed knowledge from animal experiments is available on the kind and extent of osseous and mineral metabolic disorders in genetically determined, insulin-dependent Type I diabetes. The purpose of this study was to examine the influence of the diabetic metabolic state in spontaneously diabetic BB/O(ttawa...

journal_title：Histology and histopathology

authors： Follak N,Klöting I,Ganzer D,Merk H

更新日期：2003-01-01 00:00:00

abstract：:Introduction. Gastrointestinal stromal tumors (GISTs) are characterized at the molecular level by c-kit or PDGFRA oncogene mutations. Although GISTs raised major interest in past decades, population-based studies are still rare. Materials and Methods. All GISTs diagnosed in Southern Switzerland (1999-2005) were identi...

journal_title：Histology and histopathology

authors： Mazzola P,Spitale A,Banfi S,Mazzucchelli L,Frattini M,Bordoni A

更新日期：2008-11-01 00:00:00

abstract：:Pneumadin (PNM) is a biologically active decapeptide, which has previously been found to enhanced rat adrenal growth; the mechanism is indirect and probably involves the stimulation of both arginine-vasopressin (AVP) and ACTH release. The effects of 2- and 6-day PNM administration on the atrophic adrenal cortices of r...

journal_title：Histology and histopathology

authors： Markowska A,Andreis PG,Miskowiak B,Nussdorfer GG,Malendowicz LK

更新日期：1997-07-01 00:00:00

abstract：:The study aimed at determining levels of metallothionein (MT) and Ki-67 antigen expression in adenocarcinomas of large intestine and examining relation of the expression levels with various clinical and pathological variables. The studies were performed on 81 cases of large intestine adenocarcinoma. Using immunocytoch...

journal_title：Histology and histopathology

authors： Dziegiel P,Forgacz J,Suder E,Surowiak P,Kornafel J,Zabel M

更新日期：2003-04-01 00:00:00

abstract：:The ultrastructure of four aldosterone secreting adenomas and of the adjacent zona glomerulosa has been described by the use of stereological techniques. Adenomatous cells (about 2800 microns 3 in volume) invariably displayed a striking abundance of lipid droplets, which occupied about 30% of the cytoplasm. Mitochondr...

journal_title：Histology and histopathology

authors： Belloni AS,Mantero F,Rocco S,Gottardo G,Mazzocchi G,Nussdorfer GG

更新日期：1988-07-01 00:00:00

abstract：:Osteoarthritis (OA) is characterized by cartilage attrition, subchondral bone remodeling, osteophyte formation and synovial inflammation. Perturbed homeostasis caused by inflammation, oxidative stress, mitochondrial dysfunction and proapoptotic/antiapoptotic dysregulation is known to impair chondrocyte survival in joi...

journal_title：Histology and histopathology

authors： Musumeci G,Loreto C,Carnazza ML,Strehin I,Elisseeff J

更新日期：2011-10-01 00:00:00

abstract：:Angiogenesis and bone formation are coupled during skeletal development and fracture healing. This relationship, although known for some time, has not been properly explored. Advances in the discovery of how angiogenesis is regulated in physiological processes like embryogenesis, endometrial regeneration and wound hea...

journal_title：Histology and histopathology

authors： Portal-Núñez S,Lozano D,Esbrit P

更新日期：2012-05-01 00:00:00

abstract：:The adrenal glands of lower vertebrates display a notable intermingling between steroidogenic and chromaffin tissues, which increases from Pisces to Aves. As in mammals, adrenal chromaffin cells contain and release, in addition to catecholamines, serotonin and several peptides, which may affect the secretory activity ...

journal_title：Histology and histopathology

authors： Mazzocchi G,Gottardo G,Nussdorfer GG

更新日期：1998-01-01 00:00:00

abstract：:Macrophages are important effector cells in cell-mediated immunity against intracellular infection. Among cytokines that macrophages are able to release are IL-12 and TNF alpha. IL-12 is a critical linker between the innate and adaptive cell-mediated immunity, capable of Th1 differentiation and IFN gamma release by T ...

journal_title：Histology and histopathology

authors： Xing Z

更新日期：2000-01-01 00:00:00

abstract：:Unlike other B cells, plasma cells (PC) react with only a few antibodies against haemopoietic antigens. We investigated 36 specimens exhibiting a reactive increase in PC numbers (i.e. plasmacytosis, PC hyperplasia) with a broad panel of antibodies suitable for use on formalin-fixed, paraffin-embedded tissue, and compa...

journal_title：Histology and histopathology

authors： Beschorner R,Horny HP,Petruch UR,Kaiserling E

更新日期：1999-07-01 00:00:00

abstract：:Spermatogenesis is under the control of a complex endocrine and paracrine system, including estrogen receptor (ER) signaling. In many target cells, ER promotes the transcription of c-fos and other proto-oncogenes to regulate cell growth and differentiation. Thus, in this study we evaluated the expression of the proto-...

journal_title：Histology and histopathology

authors： Araújo FC,Oliveira CA,Reis AB,Del Puerto HL,Martins AS,Reis FM

更新日期：2009-12-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) and its receptor, TrkB, are broadly expressed in the developing and adult mammalian brain. BDNF/TrkB-stimulated intracellular signaling is critical for neuronal survival, morphogenesis, and plasticity. It is well known that binding of BDNF to TrkB elicits various intracellular ...

journal_title：Histology and histopathology

authors： Numakawa T,Suzuki S,Kumamaru E,Adachi N,Richards M,Kunugi H

更新日期：2010-02-01 00:00:00

abstract：:The lower respiratory tract of the sheep was studied by light-microscopical immunocytochemistry for serotonin, cholecystokinin, somatostatin, bombesin and calcitonin during different periods of lung development; embryonic, foetal and postnatal. At embryonic period only intraepithelial serotonin-containing cells as sol...

journal_title：Histology and histopathology

authors： Balaguer L,Romano J,Ruiz-Pesini P

更新日期：1992-10-01 00:00:00

abstract：:The transport mechanism of soluble molecules throughout the interstitial matrix is closely associated with human tumor behavior in vivo. However, the examination of soluble components in histological architectures has been hampered by artifacts caused during conventional tissue preparation. In this study, the immunodi...

journal_title：Histology and histopathology

authors： Bai Y,Ohno N,Terada N,Saitoh S,Nakazawa T,Nakamura N,Katoh R,Ohno S

更新日期：2009-06-01 00:00:00

abstract：:CD45RO+ T cells are referred to as memory or helper-inducer while CD45RA+ T cells are regarded as naive or suppressor-inducer T cells. The former population predominates in the peripheral blood and even more in the synovial fluid of patients with rheumatoid arthritis, to the expense of the latter population. Within th...

journal_title：Histology and histopathology

authors： Mamoune A,Durand V,Le Goff P,Pennec YL,Youinou P,Le Corre R

更新日期：2000-04-01 00:00:00

abstract：:Current data on the influence of neuropeptides on the growth, structure and function of cells comprising the hypothalamo-pituitary-adrenal axis were presented and discussed. The action of vasopressin, oxytocin, neurotensin, bombesin, neuropeptide Y, substance P and VIP have been evaluated. The hypothesis has been intr...

journal_title：Histology and histopathology

authors： Malendowicz LK

更新日期：1993-01-01 00:00:00

abstract：:This report presents preliminary observations on the distribution of an epithelial surface antigen in human trophoblastic cells studied with the monoclonal antibody Ber-EP4 by means of an immunoperoxidase technique. Three cases of gestational choriocarcinoma and 20 cases of both villous and extravillous trophoblast, i...

journal_title：Histology and histopathology

authors： Babury RA,Moscovic EA

更新日期：1993-04-01 00:00:00

abstract：:This study deals with myocardial preservation after 24 hours of continuous, hypothermic and oxygenated perfusion with Cape Town (CT) solution, focusing on the morphological changes produced by preservation and reperfusion, and their possible relationship to the composition of the solution and the immediate hemodynamic...

journal_title：Histology and histopathology

authors： García-Poblete E,Alvarez L,Fernández H,Escudero C,Torralba A

更新日期：1998-01-01 00:00:00

abstract：:Leukemias, a heterogeneous group of hematological disorders, are characterized by ineffective hematopoiesis and morphologic abnormalities of hematopoietic cells. Thrombocytopenia is a common problem among leukemia types that can lead to hemorrhagic complications in patients. The purpose of this review article is to id...

journal_title：Histology and histopathology

authors： Shahrabi S,Behzad MM,Jaseb K,Saki N

更新日期：2018-09-01 00:00:00

abstract：:An inadequate balance between oxidant species and antioxidant mechanisms may constitute the primary mechanisms of a number of pathologies. The liver plays a central role in this balance: parenchymal hepatic cells contain and export especially high levels of the antioxidant glutathione and activated Kupffer cells relea...

journal_title：Histology and histopathology

authors： Catalá M,Pagani R,Portolés MT

更新日期：2007-04-01 00:00:00

abstract：:In the present work we analyze the cerebellum of chronic parkinsonian monkeys in order to clarify whether chronic mesencephalic depletion is associated with long term activation of the cerebellar neurons in chronic Parkinsonism. In our study, we observed a persistent activation of Purkinje cells in the cerebellum of c...

journal_title：Histology and histopathology

authors： Heman P,Barcia C,Gómez A,Ros CM,Ros-Bernal F,Yuste JE,de Pablos V,Fernandez-Villalba E,Toledo-Cárdenas MR,Herrero MT

更新日期：2012-01-01 00:00:00

abstract：:β-lapachone is a quinone of lapachol extracted from the bark of lapacho tree. Recent findings demonstrated that punched skin wounds of mice healed faster with β-lapachone treatment. The present study investigates the effects of β-lapachone on burn-wound skin of C57BL/6 mice injured by a 100 °C iron stick. Our results ...

journal_title：Histology and histopathology

authors： Fu SC,Chau YP,Lu KS,Kung HN

更新日期：2011-07-01 00:00:00

abstract：:Aneurysmal subarachnoid hemorrhage (SAH) remains a serious cerebrovascular disease. Even if SAH patients survive the initial insults, delayed cerebral ischemia (DCI) may occur at 4 days or later post-SAH. DCI is characteristics of SAH, and is considered to develop by blood breakdown products and inflammatory reactions...

journal_title：Histology and histopathology

authors： Suzuki H,Kanamaru H,Kawakita F,Asada R,Fujimoto M,Shiba M

更新日期：2020-09-30 00:00:00

abstract：:Prion diseases are characterized by the accumulation of PrPSc, an altered isoform of a normal cellular protein, PrPc. The prion hypothesis holds that the process of conformational change from PrPc to PrPSc under the influence of PrPSc constitutes the basic infectious mechanism in prion diseases. It is still unknown wh...

journal_title：Histology and histopathology

authors： Brown DR,Kretzschmar HA

更新日期：1997-07-01 00:00:00

abstract：:Ebulin f is a ribosome-inactivating protein (RIP) present in green fruits of the dwarf elder (Sambucus ebulus L). Since dwarf elder fruits are used for food and as a medicine, we assessed the study of toxicological effects and safety of ebulin f in elderly mice, comparing these results with those reported in young ani...

journal_title：Histology and histopathology

authors： Garrosa M,Jiménez P,Córdoba-Díaz D,García-Recio V,Gayoso S,Rojo MÁ,Gayoso MJ,Girbés T

更新日期：2018-09-01 00:00:00

abstract：:The influence of He-Ne laser radiation on the formation of new blood vessels in the bone marrow compartment of a regenerating area of the mid-cortical diaphysis of the tibiae of young adult rats was studied. A small hole was surgically made with a dentistry burr in the tibia and the injured area received a daily laser...

journal_title：Histology and histopathology

authors： Garavello I,Baranauskas V,da Cruz-Höfling MA

更新日期：2004-01-01 00:00:00

abstract：:In view of the limitations of conventional prognostic factors such as differentiation degree, metastatic lymph nodes, hormonal receptors and others, especially when early lesions are found, additional new markers have been studied, such as gene amplification and cell proliferation index, in order to choose the appropr...

journal_title：Histology and histopathology

authors： Sirvent JJ,Santafé M,Salvadó MT,Alvaro T,Raventós A,Palacios J

更新日期：1994-07-01 00:00:00

abstract：:Early observations that cultured mesenchymal stem cells (MSCs) could be induced to exhibit certain characteristics of osteocytes and chondrocytes led to the proposal that they could be transplanted for tissue repair through cellular differentiation. Therefore, many subsequent preclinical studies with transplanted MSCs...

journal_title：Histology and histopathology

authors： Lin CS,Xin ZC,Dai J,Lue TF

更新日期：2013-09-01 00:00:00

abstract：:Studies with scanning electron microscopy in the normal human sulcular epithelium are scarce, and no precise information exists about cell surface patterns along the epithelium, the frequencies of these patterns, or possible regional differences within the mouth. In five periodontal biopsy specimens each from the ante...

journal_title：Histology and histopathology

authors： Sánchez-Quevedo MC,Moreu G,Campos A,García JM,González-Jaranay M

更新日期：1994-01-01 00:00:00

abstract：:The FHIT gene encompassing the most active common human fragile region, FRA3B, has been proposed as a tumour suppressor gene for important common human carcinomas. The mechanism in which Fhit protein exerts its tumour suppressor activity is still obscure. To further understand the Fhit function associated with its int...

journal_title：Histology and histopathology

authors： Zhao P,Hou N,Lu Y

更新日期：2006-09-01 00:00:00