BDNF function and intracellular signaling in neurons.

abstract：:This study explores the possibility of a regulatory role for cytokine IL-10 in platelet aggregation as an active vascular repair mechanism. Endothelial cells from human umbilical cord vein were cultured in the presence of different IL-10 concentrations (0-100 ng/ml). Platelet-rich plasma was then added to these cultur...

journal_title：Histology and histopathology

authors： Gimeno MJ,Pascual G,García-Honduvilla N,Prieto A,Alvarez de Mon M,Bellón JM,Buján J

更新日期：2003-07-01 00:00:00

abstract：:Phagocytosis is an important feature of innate immunity in which invading microorganisms are engulfed, killed and degraded - and in some immune cells, their antigens presented to adaptive immune system. A closely related process, efferocytosis, removes apoptotic cells, and is essential for the maintenance of homeostas...

journal_title：Histology and histopathology

authors： Taefehshokr N,Yin C,Heit B

更新日期：2020-09-29 00:00:00

abstract：:Bacillus subtilis has been used as a classic model to study biofilm formation and sporulation process. Colonies of wild-type strains usually have a complex external morphology, but the details of their internal architecture are still undisclosed. Since bacterial biofilms fulfill the criteria to be considered tissues, ...

journal_title：Histology and histopathology

authors： Gómez-Aguado F,Corcuera MT,Gómez-Lus ML,de la Parte MA,Ramos C,García-Rey C,Alonso MJ,Prieto J

更新日期：2013-10-01 00:00:00

abstract：:Despite years of research into its pathobiology and continuing clinical trials for novel therapies, the prognosis for patients with glioblastoma (GBM) remains dismal. An important obstacle against treatment efficacy may be a high degree of intra- and inter-tumoral heterogeneity within GBMs, which may be caused by the ...

journal_title：Histology and histopathology

authors： Lee HW,Lee K,Kim DG,Yang H,Nam DH

更新日期：2016-03-01 00:00:00

abstract：:TNFalpha exerts apoptosis throughout an intracellular transduction pathway that involves the kinase proteins TRAF-2 (integration point of apoptotic and survival signals), ASK1 (pro-apoptotic protein), MEK-4 (p38 activator and metastasis suppressor gene), JNK (stress mitogen activated protein kinase) and the transcript...

journal_title：Histology and histopathology

authors： Royuela M,Rodríguez-Berriguete G,Fraile B,Paniagua R

更新日期：2008-10-01 00:00:00

abstract：:Src, a 60 kDa non-receptor tyrosine kinase, is the product of normal c-src of the human genome and member of the Src protein tyrosine kinases family (SFK). As described by Martin and Rous, a genetic recombination between c-src and the RSV oncogene of Rous sarcoma virus results in a modified Src protein, with increased...

journal_title：Histology and histopathology

authors： Chatzizacharias NA,Kouraklis GP,Giaginis CT,Theocharis SE

更新日期：2012-06-01 00:00:00

abstract：:Close contacts between endocrine insular cells and exocrine acinar, centroacinar and ductular cells occur frequently in the rat pancreas as seen by both light and electron microscopy. Islets of Langerhans are surrounded incompletely by a thin connective tissue capsule or mantle but numerous exocrine-endocrine cell con...

journal_title：Histology and histopathology

authors： Leeson TS,Leeson R

更新日期：1986-01-01 00:00:00

abstract：:The characteristics and distribution pattern of retinal afferent terminals making synaptic contacts on narrow field vertical neurons in the stratum griseum superficiale of the rabbit superior colliculus were studied using the Golgi-gold substitution technique in combination with either autoradiographic or degenerative...

journal_title：Histology and histopathology

authors： Ortega F,Doñate-Oliver F,Grandes P

更新日期：1993-01-01 00:00:00

abstract：:We describe a new technique, decalcification by perfusion, for the softening of bony tissue. The blood circulatory system was perfused in 16 rats via a cannula through the left heart ventricle with a fixative followed by New Decalc (an acidic demineralizer) for 30-240 minutes. Perfusion decalcification for 120 minutes...

journal_title：Histology and histopathology

authors： Nilsson M,Hellström S,Albiin N

更新日期：1991-07-01 00:00:00

abstract：:Discrimination of follicular cell-derived benign and malignant tumors of the thyroid is one of the major problems encountered in surgical pathology. In the present study, we evaluated the immunohistochemical expression of NGAL, an iron-binding protein involved in the infiltrative potential of cancer cells, in a cohort...

journal_title：Histology and histopathology

authors： Barresi V,Leni A,Tuccari G,Barresi G

更新日期：2012-03-01 00:00:00

abstract：:Histochemical distribution of glycoproteins, carbohydrates and proteins rich in different amino acids were studied using histological and histochemical procedures, in Senegal sole, Solea senegalensis (Kaup, 1858) larvae from hatching until day 15. Glycogen, proteins and glycoproteins were detected in the yolk-sac of t...

journal_title：Histology and histopathology

authors： Sarasquete C,González de Canales ML,Arellano JM,Muñoz-Cueto JA,Ribeiro L,Dinis MT

更新日期：1996-10-01 00:00:00

abstract：:Neurotrophins are substances that have been shown to be important in growth and remodelling phases in different types of tissue. There is no information concerning the possible occurrences of neurotrophins and their receptors in tendons. In this study, sections of both chronic painful (tendinosis) and pain-free (non-t...

journal_title：Histology and histopathology

authors： Bagge J,Lorentzon R,Alfredson H,Forsgren S

更新日期：2009-07-01 00:00:00

abstract：:Primordial germ cells (PGCs) are the founder cells of all gametes. PGCs differentiate from pluripotent epiblasts cells by mesodermal induction signals during gastrulation. Although PGCs are unipotent cells that eventually differentiate into only sperm or oocytes, they dedifferentitate to pluripotent stem cells known a...

journal_title：Histology and histopathology

authors： Kimura T,Nakano T

更新日期：2011-05-01 00:00:00

abstract：:A number of tumor suppressor and tumor-related genes exhibit promoter hypermethylation with resulting gene silencing in human cancers. In addition, several gene promoters have also been shown to become hypermethylated in non-neoplastic cells during aging. To assess the physiological consequence and clinical significan...

journal_title：Histology and histopathology

authors： Tamura G

更新日期：2004-01-01 00:00:00

abstract：:A proportion of anaplastic large cell tumours is difficult to classify on sections of routinely processed, paraffin-embedded tissue. Differentiation into large cell lymphoma, carcinoma, melanoma or sarcoma is important in order to assess prognosis and proper treatment. Although the use of immunohistochemistry has been...

journal_title：Histology and histopathology

authors： Henzen-Logmans SC,Mullink H,Vennegoor C,Hilgers J,Oort J,Meijer CJ

更新日期：1987-04-01 00:00:00

abstract：:The effects of cadmium exposure on the protein secretory functions of cultured neonatal rat hepatocytes were analyzed by both two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and electron microscopy. [35S]Methionine-labelled protein secretion was significantly depressed by cadmium exposure in a dose-depend...

journal_title：Histology and histopathology

authors： Hirano T,Ueda H,Kawahara A,Fujimoto S

更新日期：1991-01-01 00:00:00

abstract：:The coexistence of serotonin and cholecystokinin was studied in foetal sheep lungs at pseudoglandular stage of development by light microscopic immunohistochemistry. The coexistence was examined by staining consecutive sections with the different antibodies. Serotonin and cholecystokinin immunoreactivity was found wit...

journal_title：Histology and histopathology

authors： Balaguer L,Romano J,Ruiz-Pesini P

更新日期：1994-01-01 00:00:00

abstract：:The proto-oncogene, ets-1, is a transcription factor known to control the expression of a number of genes and has been postulated to play a role in cell growth, differentiation and tumour invasion. We examined 137 cases of breast carcinoma by immunohistochemistry and compared the degree of Ets-1 expression among the d...

journal_title：Histology and histopathology

authors： Katayama S,Nakayama T,Ito M,Naito S,Sekine I

更新日期：2005-01-01 00:00:00

abstract：:Recently, the characterization of mucinous tubular and spindle-cell carcinoma (MTSCC) has been established. MTSCC predominantly occurs in females. This tumor is histologically characterized by eosinophilic cytoplasm, elongated and anastomosing tubules, myxomatous stroma and low-grade nuclear cytology. Proliferation of...

journal_title：Histology and histopathology

authors： Kuroda N,Toi M,Hiroi M,Shuin T,Enzan H

更新日期：2005-01-01 00:00:00

abstract：:The low density lipoprotein receptor-related protein (LRP) 1 is a ubiquitously expressed, versatile cell surface transmembrane receptor involved in embryonic development and adult tissue homeostasis. LRP1 binds and endocytoses a broad spectrum of over 40 ligands identified thus far, including lipoproteins, extracellul...

journal_title：Histology and histopathology

authors： Wujak L,Markart P,Wygrecka M

更新日期：2016-07-01 00:00:00

abstract：:Glomerular alterations of experimental diabetes mellitus are observed in animals submitted to a reduction in renal mass, suggesting that some mechanisms responsible for the progression of renal disease are common. The aim of this study was to investigate the effect of nephrectomy on the renal function and morphology o...

journal_title：Histology and histopathology

authors： Lopes GS,Lemos CC,Mandarim-De-Lacerda CA,Bregman R

更新日期：2004-10-01 00:00:00

abstract：:Nitric oxide (NO) has opened a new and vigorous field of biological and clinical experimentation as evidenced presently by about one hundred original publications every week. Being a biological signal under physiological conditions, NO may be to pathologically affected tissues. Major insights into the ...

journal_title：Histology and histopathology

authors： Wolf G

更新日期：1997-01-01 00:00:00

abstract：:Human epithelium contains keratin, which is expressed during differentiation. Depending on the target cell type, different types of keratin are expressed, and their alterations seem to represent changes in cell properties. The basal cells of oral epithelium express keratin 5 (K5), K14, K15 and K19, but their alteratio...

journal_title：Histology and histopathology

authors： Khanom R,Sakamoto K,Pal SK,Shimada Y,Morita K,Omura K,Miki Y,Yamaguchi A

更新日期：2012-07-01 00:00:00

abstract：:Platelet-derived growth factor-A (PDGF-A) is a locally produced growth factor in the rat testis secreted by both Sertoli cells and Leydig cells. It has been suggested that PDGF-A may be involved in modulation of testosterone production and may be essential to Leydig cell differentiation, however it is not known at wha...

journal_title：Histology and histopathology

authors： Fecteau KA,Mrkonjich L,Mason JI,Mendis-Handagama SM

更新日期：2006-12-01 00:00:00

abstract：:To date, no detailed knowledge from animal experiments is available on the kind and extent of osseous and mineral metabolic disorders in genetically determined, insulin-dependent Type I diabetes. The purpose of this study was to examine the influence of the diabetic metabolic state in spontaneously diabetic BB/O(ttawa...

journal_title：Histology and histopathology

authors： Follak N,Klöting I,Ganzer D,Merk H

更新日期：2003-01-01 00:00:00

abstract：:The mandible has a mixed embryological origin, and its growth is associated with the secondary cartilage of the condyle process (CP). In this area, growth depends on an array of intrinsic and extrinsic factors that influence protein metabolism. In the present study, we used an adolescent rat model to evaluate the grow...

journal_title：Histology and histopathology

authors： de Oliveira BC,de Oliveira F,Martini DT,Prisco CR,da Silva Riguetti MM,Liberti EA,de Campos Boldrini S

更新日期：2010-01-01 00:00:00

abstract：:Immunohistochemistry of the terminal complement complex (C5b-9) and fibronectin (FN) is useful to detect myocardial ischemia preceding necrosis in the postmortem diagnosis of sudden cardiac death. The present immunohistochemical study examined connexin43 (Cx43) and zonula occludens-1 (ZO-1) as markers of early myocard...

journal_title：Histology and histopathology

authors： Kawamoto O,Michiue T,Ishikawa T,Maeda H

更新日期：2014-06-01 00:00:00

abstract：:Thyroid hormones (TH) stimulate oxidative metabolism in many tissues in the body, but testis is not one of them. Therefore, in this sense, testis is not considered as a target organ for TH. However, recent findings clearly show that TH have significant functions on the testis in general, and Leydig cells in particular...

journal_title：Histology and histopathology

authors： Mendis-Handagama SM,Ariyaratne HB

更新日期：2004-07-01 00:00:00

abstract：:HtrA1 is a secreted protein which behaves as a molecular chaperone at low temperatures and as a serine protease at high temperatures. When the placenta escapes the normal growth control mechanisms, which are present during normal pregnancy, it may develop trophoblastic diseases, such as hydatidiform mole and choriocar...

journal_title：Histology and histopathology

authors： Marzioni D,Quaranta A,Lorenzi T,Morroni M,Crescimanno C,De Nictolis M,Toti P,Muzzonigro G,Baldi A,De Luca A,Castellucci M

更新日期：2009-10-01 00:00:00

abstract：:Studies in a canine bronchogenic carcinoma model indicate that alveolar type II cells may differentiate from carcinogen-exposed epithelium of larger bronchi and generate adenocarcinomas with bronchioloalveolar and other growth patterns. In this study, we investigated whether type II cells are one of the major prolifer...

journal_title：Histology and histopathology

authors： Ten Have-Opbroek AA,Benfield JR,van Krieken JH,Dijkman JH

更新日期：1997-04-01 00:00:00