Close association of centroacinar/ductular and insular cells in the rat pancreas.

abstract：:Shotgun pellets containing bismuth (Bi) are widely used and may cause a rather intense exposure of some wild animals to Bi. A Bi shotgun pellet was implanted intramuscularly in the triceps surae muscle of 18 adult male Wistar rats. Another group of 9 animals had a Bi shotgun pellet implanted intracranially in the neoc...

journal_title：Histology and histopathology

authors： Stoltenberg M,Locht L,Larsen A,Jensen D,Danscher G

更新日期：2003-07-01 00:00:00

abstract：:The aim of this study was to demonstrate the morphology and matrix synthesis of embryonic rat liver cells (day 18 of gestation) in organoid cultures (high density cultures) with electron microscopic and immunomorphological techniques. For this purpose the cells of embryonic rat livers were isolated enzymatically and g...

journal_title：Histology and histopathology

authors： Elkasaby A,Xu D,Schröter-Kermani C,Merker HJ

更新日期：1991-04-01 00:00:00

abstract：:The primary objective of this research project was to study the role of sex steroids in the pathogenesis of cholelithiasis using the Syrian hamster as a model. In addition to the morphological examination of the gallbladder epithelium, we thought it imperative to observe the changes induced in the biliary tract in res...

journal_title：Histology and histopathology

authors： Karkare S,Adamiec-Beyga E,Gilloteaux J

更新日期：1995-07-01 00:00:00

abstract：:Immunocytochemical demonstration of metallothionein (MT) has been reported as a useful prognostic tool in human breast cancer. The aim of this study was to determine the immunohistochemical location of MT in canine mammary tumours and its possible correlation with the morphologic characteristics of these tumours. Surg...

journal_title：Histology and histopathology

authors： Fuentealba IC,Mullins JE

更新日期：1999-01-01 00:00:00

abstract：:Voltage-activated Ca2+ channels play an important role in synaptic transmission, signal processing and development. The immunohistochemical localization of Cav1.2 (alpha1C) and Cav2.3 (alpha1E) Ca2+ channels was studied in the developing and adult mouse organ of Corti using subunit-specific antibodies and fluorescent ...

journal_title：Histology and histopathology

authors： Waka N,Knipper M,Engel J

更新日期：2003-10-01 00:00:00

abstract：:Bacillary angiomatosis (BA) is a reactive vasoproliferative lesion occurring almost exclusively in immunocompromised individuals in response to infection by a bacillus closely related to Rochalimaea quintana. The commonest site of involvement is the skin, in the form of multiple erythematous nodules, but bacillary ang...

journal_title：Histology and histopathology

authors： Tsang WY,Chan JK

更新日期：1992-01-01 00:00:00

abstract：:Laminin (LAM) and fibronectin (FI) are regarded as major components of the glomerular extracellular matrix. The aim of this study was to define the distribution of LAM and FI in primary glomerulonephritis (GN) and GN of systemic lupus erythematosus (SLE) and to correlate the type of glomerular disorders with possible ...

journal_title：Histology and histopathology

authors： Nakapoulou I,Stefanaki K,Zeis PM,Papadakis J,Boletis J,Vosnidis G,Davaris P

更新日期：1993-07-01 00:00:00

abstract：:A method for the in vitro generation of granulomas and its use in the analysis of the human granulomatous response is summarized. As a target for the cellular response L3 larvae of Nippostrongylus brasiliensis are coincubated with human mononuclear blood cells, and within seven to fourteen days the development of bloo...

journal_title：Histology and histopathology

authors： Seitzer U,Haas H,Gerdes J

更新日期：2001-04-01 00:00:00

abstract：:STAT and SMAD often exert opposite biological effects on diverse cellular functions. Recent studies have shown that STAT can interface with SMAD at molecular level and that some novel molecules, such as SOCS (also called CIS) and APRO6 (also called TOB), modulate this signaling. A cofactor p300/CBP might act as a brid...

journal_title：Histology and histopathology

authors： Iwamoto T,Oshima K,Seng T,Feng X,Oo ML,Hamaguchi M,Matsuda S

更新日期：2002-01-01 00:00:00

abstract：:Cell-cell and cell-extracellular matrix adhesion are critical aspects of platelet function, regulating interactions between circulating platelets in the bloodstream with the blood vessel wall. In haemostasis, platelets adhere to the subendothelial matrix of a damaged vessel, spread over the surface and recruit additio...

journal_title：Histology and histopathology

authors： Andrews RK,Berndt MC

更新日期：1998-07-01 00:00:00

abstract：:In view of the limitations of conventional prognostic factors such as differentiation degree, metastatic lymph nodes, hormonal receptors and others, especially when early lesions are found, additional new markers have been studied, such as gene amplification and cell proliferation index, in order to choose the appropr...

journal_title：Histology and histopathology

authors： Sirvent JJ,Santafé M,Salvadó MT,Alvaro T,Raventós A,Palacios J

更新日期：1994-07-01 00:00:00

abstract：:Chaperone-mediated autophagy (CMA), a selective form of autophagy, where cellular proteins with KFERQ-like motif are targeted to the lysosome for degradation, is necessary to maintain cellular homeostasis. The role of CMA in neurodegenerative diseases has been extensively studied in the past decades, with defects in t...

journal_title：Histology and histopathology

authors： Hou T,Fan Y,Dan W,Liu B,Wang Z,Zeng J,Li L

更新日期：2020-07-01 00:00:00

abstract：:Thymidine phosphorylase (TP), thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) have been indicated as possible predictive markers for epithelial malignancies. All these three enzymes are actively involved in 5-FU metabolism. In this report, we investigated mRNA expression of these factors with real-...

journal_title：Histology and histopathology

authors： Li H,Suo Z,Zhang Y,Risberg B,Karlsson MG,Villman K,Nesland JM

更新日期：2004-01-01 00:00:00

abstract：:The salamanderfish, Lepidogalaxias salamandroides (Galaxiidae, Teleostei) is endemic to southwestern Australia and inhabits shallow, freshwater pools which evaporate during the hot summer months. Burrowing into the substrate in response to falling water levels allows these fish to aestivate for extended periods of tim...

journal_title：Histology and histopathology

authors： Collin SP,Collin HB

更新日期：1998-10-01 00:00:00

abstract：:Anthracyclines are one of the most effective anticancer drugs ever developed, but their clinical use has been hampered by the risk of severe cardiotoxicity. In this study, we investigated whether rabbits exposed to a different cumulative dose of anthracycline suffer from immunohistochemically detectable vascular toxic...

journal_title：Histology and histopathology

authors： Nachtigal P,Sterba M,Popelová O,Večeřová L,Kudláčková Z,Jirkovský E,Geršl V

更新日期：2011-05-01 00:00:00

abstract：:In this paper we report the first complete mapping of the pituitary in a tuna species. The various different adenohypophysis cell types of the bluefin tuna, Thunnus thynnus L. have been identified and located using different antisera against mammalian and piscine hormones and various histochemical techniques: PAS, Alc...

journal_title：Histology and histopathology

authors： Rodríguez-Gómez FJ,Rendón-Unceta MC,Piñuela C,Muñoz-Cueto JA,Jiménez-Tenorio N,Sarasquete C

更新日期：2001-04-01 00:00:00

abstract：:To clarify the role of REG IV, a new member of the regenerating gene (REG) family, in tumorigenesis and progression of colorectal carcinoma (CRC), 320 CRC specimens, 123 corresponding adjacent non-cancerous mucosa (ANCMs), 46 corresponding non-adjacent non-cancerous mucosa (NANCMs) and 86 adenomas were investigated im...

journal_title：Histology and histopathology

authors： Li XH,Zheng Y,Zheng HC,Takahashi H,Yang XH,Masuda S,Takano Y

更新日期：2010-04-01 00:00:00

abstract：:An inadequate balance between oxidant species and antioxidant mechanisms may constitute the primary mechanisms of a number of pathologies. The liver plays a central role in this balance: parenchymal hepatic cells contain and export especially high levels of the antioxidant glutathione and activated Kupffer cells relea...

journal_title：Histology and histopathology

authors： Catalá M,Pagani R,Portolés MT

更新日期：2007-04-01 00:00:00

abstract：:Infection with Helicobacter pylori (H. pylori) strains is linked to an increased risk of inflammation and gastric cancer. To investigate the effects of H. pylori on biological characteristics of gastric epithelial cells SGC-7901, derived from human adenocarcinoma, morphological appearances of both the pathogen and the...

journal_title：Histology and histopathology

authors： Wang P,Mei J,Tao J,Zhang N,Tian H,Fu GH

更新日期：2012-08-01 00:00:00

abstract：:Melanopsin-expressing retinal ganglion cells (mRGCs) constitute a system in the mammalian retina used for irradiance detection, regulating non-image forming functions, such as photoentrainment of circadian rhythms, control of the pupillary light reflex, masking response, light-regulated melatonin secretion, and modula...

journal_title：Histology and histopathology

authors： Esquiva G,Hannibal J

更新日期：2019-12-01 00:00:00

abstract：:Programmed death-ligand 1 (PD-L1) is an inhibitory transmembrane protein that can prevent autoimmune response. Upregulated PD-L1 serves as a predictive biomarker for patients who may respond well to immune checkpoint therapies. However, variable associations of PD-L1 level with prognoses have been reported. In this st...

journal_title：Histology and histopathology

authors： Su BC,Ting CH,Lee KY,Wu SM,Feng PH,Chan YF,Chen JY

更新日期：2020-10-28 00:00:00

abstract：:Introduction. Gastrointestinal stromal tumors (GISTs) are characterized at the molecular level by c-kit or PDGFRA oncogene mutations. Although GISTs raised major interest in past decades, population-based studies are still rare. Materials and Methods. All GISTs diagnosed in Southern Switzerland (1999-2005) were identi...

journal_title：Histology and histopathology

authors： Mazzola P,Spitale A,Banfi S,Mazzucchelli L,Frattini M,Bordoni A

更新日期：2008-11-01 00:00:00

abstract：:The International Prognostic Index (IPI) has been the basis for determining prognosis in patients with diffuse large B-cell lymphoma (DLBCL) for the past 20 years. The utility of the IPI must be reassessed in the era of immunochemotherapy. Seven risk factors at diagnosis were identified, and a maximum of 7 points were...

journal_title：Histology and histopathology

authors： Wang J,Zhou M,Xu JY,Yang YG,Zhang QG,Zhou RF,Chen B,Ouyang J,Li C

更新日期：2016-03-01 00:00:00

abstract：:Primordial germ cells (PGCs) are the founder cells of all gametes. PGCs differentiate from pluripotent epiblasts cells by mesodermal induction signals during gastrulation. Although PGCs are unipotent cells that eventually differentiate into only sperm or oocytes, they dedifferentitate to pluripotent stem cells known a...

journal_title：Histology and histopathology

authors： Kimura T,Nakano T

更新日期：2011-05-01 00:00:00

abstract：:Gp96 is the endoplasmic reticulum (ER)-resident molecular chaperone, which is involved in the correction of unfolded proteins, in the activation of proteasome-dependent ER-associated degradation of the misfolded proteins, and in activation of the protein translation that modulates polypeptide traffic into the ER. Furt...

journal_title：Histology and histopathology

authors： Jakovac H,Grebic D,Barac-Latas V,Mrakovcic I,Radosevic-Stasic B

更新日期：2013-01-01 00:00:00

abstract：:The nerve fiber distribution in the epidermis of the hairless rat skin was studied light microscopically by means of zinc iodide-osmium tetroxide staining. Two different morphological types of free nerve fiber endings could be detected: clusters of relatively thick nerve fibers stretched up through the spinous layer u...

journal_title：Histology and histopathology

authors： Müller T

更新日期：2000-04-01 00:00:00

abstract：:Studies with scanning electron microscopy in the normal human sulcular epithelium are scarce, and no precise information exists about cell surface patterns along the epithelium, the frequencies of these patterns, or possible regional differences within the mouth. In five periodontal biopsy specimens each from the ante...

journal_title：Histology and histopathology

authors： Sánchez-Quevedo MC,Moreu G,Campos A,García JM,González-Jaranay M

更新日期：1994-01-01 00:00:00

abstract：:In the lungs, neuronal M2 muscarinic receptors limit the release of acetylcholine from postganglionic cholinergic nerves. However, these receptors are not functional under certain circumstances in animal models of hyperreactivity such as occurs after exposure of sensitised animals to an allergen or during a respirator...

journal_title：Histology and histopathology

authors： Costello RW,Jacoby DB,Gleich GJ,Fryer AD

更新日期：2000-07-01 00:00:00

abstract：:The study aimed at determining levels of metallothionein (MT) and Ki-67 antigen expression in adenocarcinomas of large intestine and examining relation of the expression levels with various clinical and pathological variables. The studies were performed on 81 cases of large intestine adenocarcinoma. Using immunocytoch...

journal_title：Histology and histopathology

authors： Dziegiel P,Forgacz J,Suder E,Surowiak P,Kornafel J,Zabel M

更新日期：2003-04-01 00:00:00

abstract：:Previous studies have demonstrated a role for the beta-adrenergic system in the maturation of the fetal alveolar epithelium. Chronic blockade of beta-adrenergic binding sites has been shown to adversely effect physiologic and biochemical indices of fetal lung maturation. In the present study timed-pregnant female Spra...

journal_title：Histology and histopathology

authors： Smith DM,Sommers SS

更新日期：2002-04-01 00:00:00