Prognostic significance of metallothionein expression in correlation with Ki-67 expression in adenocarcinomas of large intestine.

abstract：:Gp96 is the endoplasmic reticulum (ER)-resident molecular chaperone, which is involved in the correction of unfolded proteins, in the activation of proteasome-dependent ER-associated degradation of the misfolded proteins, and in activation of the protein translation that modulates polypeptide traffic into the ER. Furt...

journal_title：Histology and histopathology

authors： Jakovac H,Grebic D,Barac-Latas V,Mrakovcic I,Radosevic-Stasic B

更新日期：2013-01-01 00:00:00

abstract：:The possible involvement of endogenous vasoactive intestinal peptide (VIP), cholecystokinin (CCK) and neurotensin (NT) in the control of thymocyte proliferation has been investigated in vivo in the immature rat. For this task, we have studied the effects of the administration of selective antagonists of the receptors ...

journal_title：Histology and histopathology

authors： Trejter M,Warchol JB,de Caro R,Brelinska R,Nussdorfer GG,Malendowicz LK

更新日期：2001-01-01 00:00:00

abstract：:Sixty male Wistar rats were used for this experiment and assigned at random to the control group or to the stimulation method. Control rats show cerebral asymmetry with right bias at the frontal and occipital lobes. In the case of stimulated rats the differences from the occipital zone increase while those from the fr...

journal_title：Histology and histopathology

authors： Isasa Chueca JA,Lahoz Gimeno M,Redondo Marco JA

更新日期：1992-07-01 00:00:00

abstract：:The ultrastructure of the atrial myocardium in the monkey (Macaca fascicularis) was studied after bilateral cervical vagotomy and survival times of 100, 175 and 367 days. Changes were observed in the nucleus and the cytoplasm of the myocyte. Sequestered within the nuclei of the affected myocytes were cytoplasmic organ...

journal_title：Histology and histopathology

authors： Wong WC,Yick TY,Ling EA

更新日期：1989-07-01 00:00:00

abstract：:Platelet-derived growth factor-A (PDGF-A) is a locally produced growth factor in the rat testis secreted by both Sertoli cells and Leydig cells. It has been suggested that PDGF-A may be involved in modulation of testosterone production and may be essential to Leydig cell differentiation, however it is not known at wha...

journal_title：Histology and histopathology

authors： Fecteau KA,Mrkonjich L,Mason JI,Mendis-Handagama SM

更新日期：2006-12-01 00:00:00

abstract：:The S100 gene family, which is composed of at least 24 members carrying the Ca2+ binding EF-hand motif, has been implicated in both intracellular and extracellular functions, including enzyme activities, immune responses, cytoskeleton dynamics, Ca2+ homeostasis, cell growth and cell differentiation. Altered S100 prote...

journal_title：Histology and histopathology

authors： Yao R,Davidson DD,Lopez-Beltran A,MacLennan GT,Montironi R,Cheng L

更新日期：2007-09-01 00:00:00

abstract：:Ischemic heart disease is a widespread cause of death. During infarction, myocardial injury is mediated by release of several pro-inflammatory cytokines including multifunctional interleukin-1 (IL-1). In various tissues, IL-1-mediated deleterious effects are known to be attenuated via the over-expression of natural an...

journal_title：Histology and histopathology

authors： Bonetti A,Marchini M,Ortolani F

更新日期：2008-09-01 00:00:00

abstract：:Bone marrow features in stable-phase chronic myelogenous leukemia (CML) are characterized by a striking heterogeneity which is determinable by appropriate means including representative pre-treatment trephine biopsies, immunohistochemistry and morphometry. Cell lineages involved to a variable extent consist not only o...

journal_title：Histology and histopathology

authors： Thiele J,Kvasnicka HM,Fischer R

更新日期：1999-10-01 00:00:00

abstract：:Huntington's disease (HD) is a tremendously debilitating disorder that strikes relatively young individuals and progresses rapidly over the next ten to fifteen years inducing a loss of cognitive and motor skills and eventually death occurs. The primary locus of the disorder is a polyglutamine expansion of the protein ...

journal_title：Histology and histopathology

authors： Martin B,Golden E,Keselman A,Stone M,Mattson MP,Egan JM,Maudsley S

更新日期：2008-02-01 00:00:00

abstract：:The sarcolemmal domain of rat duodenal smooth muscle cells includes caveolae and associated cytoskeletal or filamentous elements. We have used the quick-freezing, deep-etching method to examine the three dimensional relationships between these components. Replica membranes for separated strips of rat duodenal muscle l...

journal_title：Histology and histopathology

authors： Takayama I,Fujii Y,Terada N,Baba T,Kato Y,Fujino MA,Ohno S

更新日期：2000-10-01 00:00:00

abstract：:Targeting essential cellular pathways that determine neuronal and vascular survival can foster a successful therapeutic platform for the treatment of a wide variety of degenerative disorders in the central nervous system. In particular, oxidative cellular injury can precipitate several nervous system disorders that ma...

journal_title：Histology and histopathology

authors： Chong ZZ,Maiese K

更新日期：2004-04-01 00:00:00

abstract：:The effects of diethylstilbestrol (DES) and of long-acting somatostatin analog, octreotide (SMS) on the rat anterior pituitary microvasculature have been studied by means of computer-assisted image analysis. Additionally, the effects of DES and SMS on prolactin secretion and anterior pituitary cell proliferation have ...

journal_title：Histology and histopathology

authors： Pawlikowski M,Kunert-Radek J,Grochal M,Zieliński K,Kulig A

更新日期：1997-10-01 00:00:00

abstract：:A current concern about the biological effects of electromagnetic fields (EMF) is increasing with the wide spread use of X-band microwaves (MW, 8-10 GHz range). Gigahertz transverse electromagnetic (GTEM) field flat transmission lines are currently being used for experimental exposure of biological samples to high fre...

journal_title：Histology and histopathology

authors： Pérez-Bruzón RN,Del Moral A,Pérez-Castejón C,Llorente M,Vera A,Azanza MJ

更新日期：2011-09-01 00:00:00

abstract：:Renal oncocytosis is a recently established disease entity characterized by numerous oncocytic tumors and diffuse involvement of oncocytic changes in renal parenchymal epithelia. In this article, we review this disease with a focus on its clinical and pathobiological aspects. Clinically, renal oncocytosis may occur in...

journal_title：Histology and histopathology

authors： Kuroda N,Tanaka A,Ohe C,Mikami S,Nagashima Y,Sasaki T,Inoue K,Hes O,Michal M,Brunelli M,Martignoni G

更新日期：2012-11-01 00:00:00

abstract：:We used antisera to pure atrial natriuretic peptide to localise this peptide by immunocytochemistry in rat and human tissue. We showed that both rat and human atrial cardiocytes gave a positive reaction while ventricular cardiocytes were consistently negative. Peripheral islet cells in rat but not in human pancreas al...

journal_title：Histology and histopathology

authors： Lindop GB,Mallon EA,MacIntyre G

更新日期：1986-04-01 00:00:00

abstract：INTRODUCTION:Germline mutations in the tumour suppressor gene dyskeratosis congenit 1 (DKC1) cause the cancer prone syndrome called X-linked dyskeratosis congenita. The present study aims to determine whether mutations of the DKC1 gene may also be present in frequent human sporadic cancers (breast, colon and lung cance...

journal_title：Histology and histopathology

authors： Penzo M,Casoli L,Ceccarelli C,Treré D,Ludovini V,Crinò L,Montanaro L

更新日期：2013-03-01 00:00:00

abstract：:There is now evidence that estrogens and androgens are exerting their effects in different tissues throughout the body. In order to determine the sites of action of these steroids, studies have been performed to identify at the cellular level the localization of androgen receptor (AR) and the two estrogen receptor (ER...

journal_title：Histology and histopathology

authors： Pelletier G

更新日期：2000-10-01 00:00:00

abstract：:Various microscopic methods have been used to analyze the morphology and molecular distribution of cells and tissues. Using conventional procedures, however, ischemic or anoxic artifacts are inevitably caused by tissue-resection or perfusion-fixation. The in vivo cryotechnique (IVCT) was developed to overcome these pr...

journal_title：Histology and histopathology

authors： Ohno N,Terada N,Saitoh S,Zhou H,Fujii Y,Ohno S

更新日期：2007-11-01 00:00:00

abstract：:Monoclonal antibody against histiocytosis X cells (HXCs) was established. The antigen was the cell membrane of HXCs from the submandibular lesion of a 63-year-old man who had been diagnosed as an adult type of histiocytosis X (HX) and whose HXCs had numerous Birbeck granules (BGs). The obtained monoclonal antibody, na...

journal_title：Histology and histopathology

authors： Ishikawa M,Matsuda M,Imai Y

更新日期：1992-07-01 00:00:00

abstract：:Spermatogenesis is under the control of a complex endocrine and paracrine system, including estrogen receptor (ER) signaling. In many target cells, ER promotes the transcription of c-fos and other proto-oncogenes to regulate cell growth and differentiation. Thus, in this study we evaluated the expression of the proto-...

journal_title：Histology and histopathology

authors： Araújo FC,Oliveira CA,Reis AB,Del Puerto HL,Martins AS,Reis FM

更新日期：2009-12-01 00:00:00

abstract：:The view of how astrocytes, a type of glial cells, contribute to the functioning of the central nervous system (CNS) has changed greatly in the last decade. Although glial cells outnumber neurons in the mammalian brain, it was considered for over a century that they played a subservient role to neurons. This view chan...

journal_title：Histology and histopathology

authors： Potokar M,Stenovec M,Kreft M,Gabrijel M,Zorec R

更新日期：2011-02-01 00:00:00

abstract：:Gliomas are the most common intracranial malignant tumors in humans, and high-grade gliomas in particular pose a unique challenge due to their propensity for proliferation and tissue invasion. Our understanding of glioma oncogenesis, proliferation, and invasion has been greatly advanced in the past 10 years as researc...

journal_title：Histology and histopathology

authors： Ware ML,Berger MS,Binder DK

更新日期：2003-01-01 00:00:00

abstract：:Orexins A and B are two hypothalamic peptides, involved in the central regulation of feeding, which act through two receptor subtypes, named OX1R and OX2R. OX1R is selective for orexin-A, and OX2R binds both orexins. We have investigated the effects of three subcutaneous injections of 10 nmol/kg body weight of orexins...

journal_title：Histology and histopathology

authors： Malendowicz LK,Jedrzejczak N,Belloni AS,Trejter M,Hochól A,Nussdorfer GG

更新日期：2001-07-01 00:00:00

abstract：AIMS:The expression patterns of TGFB signaling proteins, such as TGFB1/2, TGFBR1(ALK5), TGFBR2, SMAD1/2/3, SMAD2/3, SMAD4, SMAD7, and of downstream targets of TGFB signaling, CDKN1A (p21CIP1), CDKN1B (p27KIP1), MYC, CDC25A, TP53, and RELA (p65NF-kB) were investigated in gastric carcinomas and other gastric lesions. ME...

journal_title：Histology and histopathology

authors： Kim SH,Lee SH,Choi YL,Wang LH,Park CK,Shin YK

更新日期：2008-12-01 00:00:00

abstract：:In this article we review immunocytochemical localization studies using a monoclonal antibody raised against the 31 kD subunit of bovine H(+)-ATPase, and indirect immunofluorescent staining. In the proximal tubules there is intense H(+)-ATPase staining along the brush borders of S1 and S2, and linear subvillar invagin...

journal_title：Histology and histopathology

authors： Bastani B

更新日期：1997-07-01 00:00:00

abstract：:Lymphatic vessels afferent to the popliteal nodes in young adult rats and guinea pigs were interrupted at the lowest edge of the popliteal fossa, and regressive changes in the nodes occurring 4 to 16 or 18 weeks after surgery were re-examined histologically. In the rat, some popliteal nodes were drained by lymphatic c...

journal_title：Histology and histopathology

authors： Hoshi H,Takemoto R,Nagata H,Horie K,Murakami G,Suzuki S

更新日期：1993-07-01 00:00:00

abstract：:Shotgun pellets containing bismuth (Bi) are widely used and may cause a rather intense exposure of some wild animals to Bi. A Bi shotgun pellet was implanted intramuscularly in the triceps surae muscle of 18 adult male Wistar rats. Another group of 9 animals had a Bi shotgun pellet implanted intracranially in the neoc...

journal_title：Histology and histopathology

authors： Stoltenberg M,Locht L,Larsen A,Jensen D,Danscher G

更新日期：2003-07-01 00:00:00

abstract：:The rapid Golgi method, combined with current optical and electronmicroscopical techniques, was used in three central gangliogliomas and in one dysplastic gangliocytoma of the cerebellum to study the morphology of ganglionic cells. Gangliogliomas were composed of bipolar, fusiform and radiate cells with dense core and...

journal_title：Histology and histopathology

authors： Ferrer I,Martí E,Guionnet N,Bella R,Serrano T,Towse J,Conesa G,Isamat F

更新日期：1990-07-01 00:00:00

abstract：:A study was undertaken to analyze the spatio-temporal pattern of mesenchymal cell proliferation in the developing palate of quail. Quail embryos were grown in shell-less culture. The developing palates were labelled with 3H-thymidine between culture days 2-6 (which corresponded in vivo incubation days 5-9), and proces...

journal_title：Histology and histopathology

authors： Hehn BM,Young AV,Shah RM

更新日期：1995-07-01 00:00:00

abstract：:The aims of the present study were to apply the AMG technique for localization of mercury at the light and electron microscopic level in the ovary of crucian carp after exposure to mercuric chloride and to find out if this heavy metal induces expression of caspase-3. Depending on the stage of ovarian follicle developm...

journal_title：Histology and histopathology

authors： Zarnescu O

更新日期：2009-02-01 00:00:00