Bone marrow histopathology in chronic myelogenous leukemia (CML)--evaluation of distinctive features with clinical impact.

abstract：:Macrophages play important roles in host defense mechanisms. In the brain, besides microglial cells, meningeal macrophages are present. However, the pathobiological characteristics of meningeal macrophages in rats remain to be investigated. In normal meninx, immunohistochemically, macrophages reacting to CD163 (macrop...

journal_title：Histology and histopathology

authors： Yamate J,Ishimine S,Izawa T,Kumagai D,Kuwamura M

更新日期：2009-01-01 00:00:00

abstract：:The bronchial-associated lymphoid tissue (BALT) is a lymphoepithelial organ, related to the immune defence of the lung and to alveolar clearance, which changes size in certain states of disease. Changes in the size of BALT were quantified and compared, and Spearman's test was used to test the relation with the bronchi...

journal_title：Histology and histopathology

authors： Escolar Castellón JD,Escolar Castellón A,Roche Roche PA,Miñana Amada C

更新日期：1992-07-01 00:00:00

abstract：:Early observations that cultured mesenchymal stem cells (MSCs) could be induced to exhibit certain characteristics of osteocytes and chondrocytes led to the proposal that they could be transplanted for tissue repair through cellular differentiation. Therefore, many subsequent preclinical studies with transplanted MSCs...

journal_title：Histology and histopathology

authors： Lin CS,Xin ZC,Dai J,Lue TF

更新日期：2013-09-01 00:00:00

abstract：:Recent evidence has shown that vascular function depends not only on cells within the vessels, but is also significantly modulated by circulating cells derived from the bone marrow. A number of studies indicate that an early reendothelialization by circulating endothelial precursors after vascular injury prevents exce...

journal_title：Histology and histopathology

authors： Forte A,Cipollaro M,Cascino A,Galderisi U

更新日期：2007-05-01 00:00:00

abstract：:During mammalian mitosis, a proofreading network called the spindle assembly checkpoint (SAC) is indispensable for ensuring the fidelity of chromosome segregation. An inhibitory SAC signal is deputed to inhibits mitotic cell-cycle progression in response to misaligned chromosomes until such imperfections are rectified...

journal_title：Histology and histopathology

authors： Homer HA

更新日期：2006-08-01 00:00:00

abstract：:Since endometriosis is a proliferative disease we evaluated the presence of anti-apoptotic factor (Bcl-2) and pro-apoptotic factor (Bax) in deep pelvic endometriosis. A Cross-sectional observational study was performed at Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil. Forty women aged 26 to 46 years with ...

journal_title：Histology and histopathology

authors： Abdalla Ribeiro HS,Galvāo MA,Aoki T,Aldrighi JM,Ribeiro PA

更新日期：2014-09-01 00:00:00

abstract：:Fluoxetine shows controversial lung effects as it prevents pulmonary hypertension in adult rats but exposure during gestation causes pulmonary hypertension in neonatal rats. In the present study, we tested the null hypothesis that the antidepressant drug fluoxetine does not modify the development of bronchopulmonary d...

journal_title：Histology and histopathology

authors： Porzionato A,Zaramella P,Macchi V,Grisafi D,Salmaso R,Baraldi M,Fornaro E,Tassone E,Masola V,Onisto M,Chiandetti L,De Caro R

更新日期：2012-12-01 00:00:00

abstract：:The primary objective of this research project was to study the role of sex steroids in the pathogenesis of cholelithiasis using the Syrian hamster as a model. In addition to the morphological examination of the gallbladder epithelium, we thought it imperative to observe the changes induced in the biliary tract in res...

journal_title：Histology and histopathology

authors： Karkare S,Adamiec-Beyga E,Gilloteaux J

更新日期：1995-07-01 00:00:00

abstract：:Epidermal proliferation, inflammatory changes and microvascular augmentation are prominent features of chronic cutaneous psoriatic lesions. The objective of this study was the investigation of blood and lymphatic microvascular changes in relation to epidermal changes and inflammatory infiltration in dermis. Immunohist...

journal_title：Histology and histopathology

authors： Výbohová D,Adamicová K,Mellová Y,Hešková G

更新日期：2017-05-01 00:00:00

abstract：:Earlier we reported that atherosclerotic lesions of apoE-deficient mice contained cells which stained positively with anti-S-100 antibody and that cells exhibiting the ultrastructural features of dendritic cells were present in the aortic lesions. These observations suggested that dendritic cells might be involved in ...

journal_title：Histology and histopathology

authors： Bobryshev YV,Taksir T,Lord RS,Freeman MW

更新日期：2001-07-01 00:00:00

abstract：:Differentiating nonspecific interstitial pneumonia (NSIP) from usual interstitial pneumonia (UIP) is important for the determination of both treatment and prognosis. Using two-dimensional fluorescence difference gel electrophoresis (2D-DIGE), we examined 8 UIPs, 8 NSIPs, and 30 normal lung tissues. Comparisons with co...

journal_title：Histology and histopathology

authors： Ohara I,Aida S,Shimazaki H,Kobayashi H,Tsuda H,Toda T,Nakanishi K,Tamai S

更新日期：2014-03-01 00:00:00

abstract：:Spinal cord injury (SCI) is one of the most destructive traumatic diseases in human beings. The balance of inflammation in the microenvironment is crucial to the repair process of spinal cord injury. Inflammatory cytokines are direct mediators of local lesion inflammation and affect the prognosis of spinal cord injury...

journal_title：Histology and histopathology

authors： Lin S,Xu C,Lin J,Hu H,Zhang C,Mei X

更新日期：2020-10-01 00:00:00

abstract：:Previous studies have demonstrated a role for the beta-adrenergic system in the maturation of the fetal alveolar epithelium. Chronic blockade of beta-adrenergic binding sites has been shown to adversely effect physiologic and biochemical indices of fetal lung maturation. In the present study timed-pregnant female Spra...

journal_title：Histology and histopathology

authors： Smith DM,Sommers SS

更新日期：2002-04-01 00:00:00

abstract：:Chaperone-mediated autophagy (CMA), a selective form of autophagy, where cellular proteins with KFERQ-like motif are targeted to the lysosome for degradation, is necessary to maintain cellular homeostasis. The role of CMA in neurodegenerative diseases has been extensively studied in the past decades, with defects in t...

journal_title：Histology and histopathology

authors： Hou T,Fan Y,Dan W,Liu B,Wang Z,Zeng J,Li L

更新日期：2020-07-01 00:00:00

abstract：:Thymidine phosphorylase (TP), thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) have been indicated as possible predictive markers for epithelial malignancies. All these three enzymes are actively involved in 5-FU metabolism. In this report, we investigated mRNA expression of these factors with real-...

journal_title：Histology and histopathology

authors： Li H,Suo Z,Zhang Y,Risberg B,Karlsson MG,Villman K,Nesland JM

更新日期：2004-01-01 00:00:00

abstract：:Studies in a canine bronchogenic carcinoma model indicate that alveolar type II cells may differentiate from carcinogen-exposed epithelium of larger bronchi and generate adenocarcinomas with bronchioloalveolar and other growth patterns. In this study, we investigated whether type II cells are one of the major prolifer...

journal_title：Histology and histopathology

authors： Ten Have-Opbroek AA,Benfield JR,van Krieken JH,Dijkman JH

更新日期：1997-04-01 00:00:00

abstract：:The present study describes the use of a microwave processing protocol for the rapid histopathological and immunohistochemical diagnosis of bovine rabies. Immunohistochemistry has been used for rabies diagnosis in formalin-fixed tissue with satisfactory results, although the time to diagnosis is considerably longer th...

journal_title：Histology and histopathology

authors： Abreu CC,Nakayama PA,Nogueira CI,Mesquita LP,Lopes PF,Varaschin MS,Seixas Jdo N,Ferreira E,Bezerra PS Jr

更新日期：2012-09-01 00:00:00

abstract：:Neurotrophins are substances that have been shown to be important in growth and remodelling phases in different types of tissue. There is no information concerning the possible occurrences of neurotrophins and their receptors in tendons. In this study, sections of both chronic painful (tendinosis) and pain-free (non-t...

journal_title：Histology and histopathology

authors： Bagge J,Lorentzon R,Alfredson H,Forsgren S

更新日期：2009-07-01 00:00:00

abstract：:The renin-angiotensin system (RAS) and tubuloglomerular feedback (TGF) are central to the maintenance of blood pressure and body fluid composition. Renin, NO synthase-1 (NOS-1), and cyclooxygenase-2 (COX-2) are key regulators of the RAS and TGF. In the present study, to investigate species-specific differences in the ...

journal_title：Histology and histopathology

authors： Ichii O,Yabuki A,Ojima T,Matsumoto M,Taniguchi K,Suzuki S

更新日期：2008-02-01 00:00:00

abstract：:Ischemic heart disease is a widespread cause of death. During infarction, myocardial injury is mediated by release of several pro-inflammatory cytokines including multifunctional interleukin-1 (IL-1). In various tissues, IL-1-mediated deleterious effects are known to be attenuated via the over-expression of natural an...

journal_title：Histology and histopathology

authors： Bonetti A,Marchini M,Ortolani F

更新日期：2008-09-01 00:00:00

abstract：:Chronic liver diseases are commonly associated with tissue hypoxia that may cause inflammation, oxidative stress, liver cell injury and increased nuclear transcriptional regulation. The hepatic response to chronic hypoxia at the molecular level has not yet been clearly understood until now. The aim of this study is to...

journal_title：Histology and histopathology

authors： Lau TY,Xiao J,Liong EC,Liao L,Leung TM,Nanji AA,Fung ML,Tipoe GL

更新日期：2013-04-01 00:00:00

abstract：:Within the last few years, advances have been made regarding perivascular nerves and the endothelium of the vascular system, both potentially important in the understanding of the mechanisms of local control of blood flow. Endothelin-1 (ET-1) has been identified in rat cerebrovascular nerves, neuropeptide Y (NPY) has ...

journal_title：Histology and histopathology

authors： Loesch A

更新日期：2002-04-01 00:00:00

abstract：:Emperipolesis has recently been described as a constant feature of "biphasic squamoid" papillary renal cell carcinoma (BPRCC). We also noticed this in some high-grade (HG) RCC, which promoted the present study to estimate the incidence of emperipolesis in RCCs and to describe them in further detail. 14 cases of HGRCC ...

journal_title：Histology and histopathology

authors： Rotterova P,Martinek P,Alaghehbandan R,Prochazkova K,Damjanov I,Rogala J,Suster S,Perez-Montiel D,Alvarado-Cabrero I,Sperga M,Svajdler M,Michalova K,Pivovarcikova K,Daum O,Hora M,Dusek M,Ondic O,Stehlikova A,Michal M

更新日期：2018-03-01 00:00:00

abstract：:Huntington's disease (HD) is a tremendously debilitating disorder that strikes relatively young individuals and progresses rapidly over the next ten to fifteen years inducing a loss of cognitive and motor skills and eventually death occurs. The primary locus of the disorder is a polyglutamine expansion of the protein ...

journal_title：Histology and histopathology

authors： Martin B,Golden E,Keselman A,Stone M,Mattson MP,Egan JM,Maudsley S

更新日期：2008-02-01 00:00:00

abstract：:Mitochondrial transcription factor A (mtTFA) plays a crucial role in both the transcription and maintenance of mitochondrial DNA. A high expression of mtTFA has been demonstrated in several solid tumors, and is closely associated with cancer cell survival/apoptosis and growth. However, its expression pattern in pancre...

journal_title：Histology and histopathology

authors： Kimura T,Kitada S,Uramoto H,Zhi L,Kawatsu Y,Takeda T,Horie S,Nabeshima A,Noguchi H,Sasaguri Y,Izumi H,Kohno K,Yamada S

更新日期：2015-02-01 00:00:00

abstract：:Recent studies have shown that papillary renal cell carcinoma (RCC) is clinically and genotypically a distinct entity. Papillary RCCs account for about 10-15% of renal parenchymal neoplasms. Macroscopically, the cut surface is yellow or brown in color and large tumors frequently show cystic change. Hemorrhage and necr...

journal_title：Histology and histopathology

authors： Kuroda N,Toi M,Hiroi M,Enzan H

更新日期：2003-04-01 00:00:00

abstract：:There is now evidence that estrogens and androgens are exerting their effects in different tissues throughout the body. In order to determine the sites of action of these steroids, studies have been performed to identify at the cellular level the localization of androgen receptor (AR) and the two estrogen receptor (ER...

journal_title：Histology and histopathology

authors： Pelletier G

更新日期：2000-10-01 00:00:00

abstract：:F10, a subline of the B16 mouse melanoma cell line, is itself the parent of the more metastatic BL6 line. BL6 cells differ from F10 cells by an alteration of the gene encoding the B56gamma regulatory subunit of protein phosphatase 2A (PP2A), which results in mRNA encoding a truncated variant of the subunit (deltagamma...

journal_title：Histology and histopathology

authors： Koma YI,Ito A,Watabe K,Kimura SH,Kitamura Y

更新日期：2004-04-01 00:00:00

abstract：:Using histopathological analysis of semi-thin sections stained with toluidine blue, we observed profound pathological changes in the islets of Langerhans of hamsters infected with the scrapie agent (strain 139H). These included cytoplasmic vesicles, nuclear swelling, and vacuolization in the islet cells. Two types of ...

journal_title：Histology and histopathology

authors： Ye X,Carp RI

更新日期：1996-01-01 00:00:00

abstract：:The photoreceptors of the barred owl (Strix varia) consist of rods, single cones and unequal double cones present in a ratio of about 35:1:3. In the light-adapted condition the rods are of uniform diameter along their entire length and are therefore not felt to undergo photomechanical changes. The rod outer segment co...

journal_title：Histology and histopathology

authors： Braekevelt CR,Smith SA,Smith BJ

更新日期：1996-01-01 00:00:00