Molecular biology of glioma tumorigenesis.

abstract：:Acetylcholinesterase (AchE)-positive afferent axons in the mucosa of the cat urinary bladder were examined in the present experiments. Small-sized dorsal root ganglion cells containing AchE enzyme activity were labelled by injection of retrograde tracer (wheat germ agglutinin conjugated to enzymatically inactive horse...

journal_title：Histology and histopathology

authors： Wakabayashi Y,Kojima Y,Makiura Y,Tomoyoshi T,Maeda T

更新日期：1995-07-01 00:00:00

abstract：:A technique for staining the nucleolar organizer regions (NORs) in tumor cells applied to smears from brain tumor biopsy specimens is described. This technique provides a rapid intraoperative evaluation of the proliferative activity in cerebral neoplasms and is a valuable complement to hematoxylineosin stained smears,...

journal_title：Histology and histopathology

authors： Vaquero J,Martínez R,Arias A,Oya S

更新日期：1991-10-01 00:00:00

abstract：:Angiogenesis and bone formation are coupled during skeletal development and fracture healing. This relationship, although known for some time, has not been properly explored. Advances in the discovery of how angiogenesis is regulated in physiological processes like embryogenesis, endometrial regeneration and wound hea...

journal_title：Histology and histopathology

authors： Portal-Núñez S,Lozano D,Esbrit P

更新日期：2012-05-01 00:00:00

abstract：:The effects of diethylstilbestrol (DES) and of long-acting somatostatin analog, octreotide (SMS) on the rat anterior pituitary microvasculature have been studied by means of computer-assisted image analysis. Additionally, the effects of DES and SMS on prolactin secretion and anterior pituitary cell proliferation have ...

journal_title：Histology and histopathology

authors： Pawlikowski M,Kunert-Radek J,Grochal M,Zieliński K,Kulig A

更新日期：1997-10-01 00:00:00

abstract：:During endotoxic shock, the liver exerts a lipopolysaccharide (LPS) clearance function with the participation of both parenchymal and sinusoidal cells. Liver damage could be caused by LPS direct action, hypoxia and/or inflammatory mediators released by Kupffer cells. The aim of this study is to establish an experiment...

journal_title：Histology and histopathology

authors： Pagani R,Portolés MT,Arahuetes R,Ainaga MJ,Machín C,Rua C

更新日期：1996-07-01 00:00:00

abstract：:This report describes the gross, histopathological, immunocytochemical and electron microscopic findings in a cat with systemic cryptococcosis and feline immunodeficiency virus (FIV) infection. Lymphadenopathy and cloudiness of leptomeninges were the major gross findings. Numerous cryptococcal yeasts were found in lym...

journal_title：Histology and histopathology

authors： Ramos-Vara JA,Ferrer L,Visa J

更新日期：1994-04-01 00:00:00

abstract：:Programmed death-ligand 1 (PD-L1) is an inhibitory transmembrane protein that can prevent autoimmune response. Upregulated PD-L1 serves as a predictive biomarker for patients who may respond well to immune checkpoint therapies. However, variable associations of PD-L1 level with prognoses have been reported. In this st...

journal_title：Histology and histopathology

authors： Su BC,Ting CH,Lee KY,Wu SM,Feng PH,Chan YF,Chen JY

更新日期：2020-10-28 00:00:00

abstract：:Knee osteoarthritis (KOA) is the most common progressive joint disorder associated with disability in the world. As a chronic disease, KOA has multifactorial etiology. However, the poor self-healing ability of the articular cartilage due to its intrinsic tissue hypovascularity and hypocellularity seems to be directly ...

journal_title：Histology and histopathology

authors： Gu X,Li C,Yin F,Yang G

更新日期：2018-07-01 00:00:00

abstract：:The pancreatic-duct system was observed during the initial stage of type 1 diabetes in C57BL/6J mice rendered diabetic with low doses of streptozocin. Light microscopy revealed that the ducts located in close proximity to islets (islet ducts) were involved in the infiltrating process: inflammatory cells extended from ...

journal_title：Histology and histopathology

authors： Papaccio G,Strate C,Linn T

更新日期：1994-07-01 00:00:00

abstract：:Erythema dyschromicum perstans (EDP) and vitiligo are two cutaneous pigmentary dermatoses of unknown etiology. In the present study, the leukocyte infiltrates in the affected skin of EDP and vitiligo patients were studied using the avidin-biotin (ABC) immunoperoxidase technique and monoclonal antibodies which recognis...

journal_title：Histology and histopathology

authors： Gross A,Tapia FJ,Mosca W,Perez RM,Briceño L,Henriquez JJ,Convit J

更新日期：1987-07-01 00:00:00

abstract：:Sphingosine kinase functions to phosphorylate sphingosine to sphingosine 1-phosphate (S1P) to keep balance in the metabolites of sphingolipids. There are two isoforms of sphingosine kinase, sphingosine kinase 1 (SphK1) and sphingosine kinase 2 (SphK2). Although SphK1 and SphK2 share high sequence similarity, SphK2 has...

journal_title：Histology and histopathology

authors： Song DD,Zhou JH,Sheng R

更新日期：2018-05-01 00:00:00

abstract：:Representative tumour sections from 468 patients with invasive breast cancer were immunostained for cyclooxygenase-2 (COX-2) and evaluated. The relationships between COX-2 expression, clinical outcome and various clinicopathological variables, including tumour vascularity and disseminated tumour cells (DTC) in the bon...

journal_title：Histology and histopathology

authors： Dhakal HP,Naume B,Synnestvedt M,Borgen E,Kaaresen R,Schlichting E,Wiedswang G,Bassarova A,Holm R,Giercksky KE,Nesland JM

更新日期：2012-10-01 00:00:00

abstract：:This study concerns the results of penile biopsies in 50 patients aged 27 to 80, with secondary impotence removed with a biopty gun or during penile surgery. The biopty gun specimens were equally representative as the open biopsy ones. The cause and the degree of erectile dysfunction were determined by clinical and la...

journal_title：Histology and histopathology

authors： Malovrouvas D,Petraki C,Constantinidis E,Petraki K,Antoniadis G,Constantinidis C,Kranidis A

更新日期：1994-07-01 00:00:00

abstract：:GLI-similar (Glis) 1-3 proteins constitute a subfamily of the Krüppel-like zinc finger transcription factors that are closely related to the Gli family. Glis1-3 play critical roles in the regulation of a number of physiological processes and have been implicated in several pathologies. Mutations in GLIS2 have been lin...

journal_title：Histology and histopathology

authors： Kang HS,ZeRuth G,Lichti-Kaiser K,Vasanth S,Yin Z,Kim YS,Jetten AM

更新日期：2010-11-01 00:00:00

abstract：:mTOR is a member of the PI3K/Akt/mTOR signaling pathway that participates in cell growth, proliferation, protein synthesis, transcription, angiogenesis, apoptosis and autophagy. mTOR and MAPK pahways are two important key signal pathways which are related to each other. We investigated the role of mTOR and other signa...

journal_title：Histology and histopathology

authors： Ekizceli G,Inan S,Oktem G,Onur E,Ozbilgin K

更新日期：2020-11-01 00:00:00

abstract：:Osteoarthritis (OA) is characterized by cartilage attrition, subchondral bone remodeling, osteophyte formation and synovial inflammation. Perturbed homeostasis caused by inflammation, oxidative stress, mitochondrial dysfunction and proapoptotic/antiapoptotic dysregulation is known to impair chondrocyte survival in joi...

journal_title：Histology and histopathology

authors： Musumeci G,Loreto C,Carnazza ML,Strehin I,Elisseeff J

更新日期：2011-10-01 00:00:00

abstract：:Studies with scanning electron microscopy in the normal human sulcular epithelium are scarce, and no precise information exists about cell surface patterns along the epithelium, the frequencies of these patterns, or possible regional differences within the mouth. In five periodontal biopsy specimens each from the ante...

journal_title：Histology and histopathology

authors： Sánchez-Quevedo MC,Moreu G,Campos A,García JM,González-Jaranay M

更新日期：1994-01-01 00:00:00

abstract：:Thyroid glands from 7 marmosets (Callithrix jacchus) of different age groups (newborn, 2 weeks, 2, 7, 8 and 11 months, and 8 years) were grown as organ culture according to Trowell at the medium/air interphase for 3 to 30 days. The morphology of thyroid tissue was well preserved until the end of the culture period. Ne...

journal_title：Histology and histopathology

authors： Maile S,Merker HJ

更新日期：1995-10-01 00:00:00

abstract：:Ultrastructural changes of the parathyroid glands of pinealectomized golden hamsters were investigated. The main changes in the parathyroid glands 1 hour and 1 day after pinealectomy compared with the control and sham-operated groups were an increase of the Golgi complexes, cisternae of the granular endoplasmic reticu...

journal_title：Histology and histopathology

authors： Chen H,Shoumura S,Emura S,Utsumi M,Yamahira T,Isono H

更新日期：1990-10-01 00:00:00

abstract：:The acute and chronic effects of bombesin (BM) on the structure and function of rat adrenal cortex were investigated by morphometric and radioimmunological techniques. An intraperitoneal bolus injection of 2 micrograms/rat BM markedly raised plasma corticosterone (B) concentration (PBC). The intraperitoneal BM infusio...

journal_title：Histology and histopathology

authors： Malendowicz LK,Nussdorfer GG,Miskowiak B,Majchrzak M

更新日期：1995-01-01 00:00:00

abstract：:Ewing-like sarcomas (ELS) are a heterogenous group of tumors that frequently affect pediatric and young adult patients. Accurate classification and distinction from the Ewing sarcoma family of tumor (ESFT) is decisive in patient management. ELS share a significant morphologic, immunohistochemical and clinical overlap ...

journal_title：Histology and histopathology

authors： Machado I,Navarro S,Llombart-Bosch A

更新日期：2016-11-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) belong to the TGF-Beta superfamily and are vital bone inductive factors. BMPs also play important roles during embryonic development and the postnatal homeostasis of various organs and tissues, by controlling cellular differentiation, proliferation and apoptosis. Prostate cancer is t...

journal_title：Histology and histopathology

authors： Ye L,Lewis-Russell JM,Kyanaston HG,Jiang WG

更新日期：2007-10-01 00:00:00

abstract：:The present review examines various aspects of the developmental expression of neuropeptides and of their receptors in mammalian retinas, emphasizing their possible roles in retinal maturation. Different peptidergic systems have been investigated with some detail during retinal development, including substance P (SP),...

journal_title：Histology and histopathology

authors： Bagnoli P,Dal Monte M,Casini G

更新日期：2003-10-01 00:00:00

abstract：:The nerve fiber distribution in the epidermis of the hairless rat skin was studied light microscopically by means of zinc iodide-osmium tetroxide staining. Two different morphological types of free nerve fiber endings could be detected: clusters of relatively thick nerve fibers stretched up through the spinous layer u...

journal_title：Histology and histopathology

authors： Müller T

更新日期：2000-04-01 00:00:00

abstract：:Macrophages play important roles in host defense mechanisms. In the brain, besides microglial cells, meningeal macrophages are present. However, the pathobiological characteristics of meningeal macrophages in rats remain to be investigated. In normal meninx, immunohistochemically, macrophages reacting to CD163 (macrop...

journal_title：Histology and histopathology

authors： Yamate J,Ishimine S,Izawa T,Kumagai D,Kuwamura M

更新日期：2009-01-01 00:00:00

abstract：:Nitric oxide (NO) is a biological messenger molecule produced by one of the essential amino acids L-arginine by the catalytic action of the enzyme NO synthase (NOS). The dual role of NO as a protective or toxic molecule is due to several factors, such as; the isoform of NOS involved, concentration of NO and the type o...

journal_title：Histology and histopathology

authors： Thippeswamy T,McKay JS,Quinn JP,Morris R

更新日期：2006-04-01 00:00:00

abstract：:A rat IgG2a monoclonal antibody against a stage-specific fetal glycoprotein with a molecular mass of 68 kDa (FGP68) was produced and applied to paraffin sections. This monoclonal antibody was used to compare the expression of FGP68 with that of both alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) in 75 hepa...

journal_title：Histology and histopathology

authors： Kato M,Shinozawa T,Kato S,Terada T

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Expression of hypoxia-related tissue factors in 1p-aberrant oligodendroglial neoplasms diminishes patient outcome. Differentiated embryo-chondrocyte expressed gene 1 (DEC1) has been described as novel hypoxia-related tissue factor. In our study, we assessed the expression of DEC1 in 1p aberrant oligodendrogl...

journal_title：Histology and histopathology

authors： Preusser M,Birner P,Ambros IM,Ambros PF,Budka H,Harris AL,Hainfellner JA

更新日期：2005-10-01 00:00:00

abstract：:Duodenal samples were taken from similar locations in six cats, processed, stained, and examined via light microscope. There were no prominent circular folds (plicae circulares) or stratum compactum (lamina subglandularis). The 1072 microns x 201 microns villi were covered by 46 microns high columnar epitheliocytes pr...

journal_title：Histology and histopathology

authors： Henry RW,al-Bagdadi FK

更新日期：1986-10-01 00:00:00

abstract：:The present study analyzed the temporal and spatial expression of TGF-beta isoforms and activated pSmad2 and p38MAPK during epithelial debridement wound repair, using chick cornea by immunohistochemistry. Normal corneas showed low-level TGF-betas staining. Following wounding, TGF-beta1 expression was strong in the Bow...

journal_title：Histology and histopathology

authors： Huh MI,Chang Y,Jung JC

更新日期：2009-11-01 00:00:00