Expression of cyclooxygenase-2 in invasive breast carcinomas and its prognostic impact.

abstract：:Nitric oxide (NO) is a biological messenger molecule produced by one of the essential amino acids L-arginine by the catalytic action of the enzyme NO synthase (NOS). The dual role of NO as a protective or toxic molecule is due to several factors, such as; the isoform of NOS involved, concentration of NO and the type o...

journal_title：Histology and histopathology

authors： Thippeswamy T,McKay JS,Quinn JP,Morris R

更新日期：2006-04-01 00:00:00

abstract：:Cyclin A, cyclin E, BUBR1, MAD2 and Aurora A are all cell-cycle regulatory proteins and have been proven to play crucial roles in carcinogenesis. However, their expression patterns in invasive ductal breast carcinoma (IDBC) are controversial and unclear. In this study, we examined the expression status of these candid...

journal_title：Histology and histopathology

authors： Du J,Du Q,Zhang Y,Sajdik C,Ruan Y,Tian XX,Fang WG

更新日期：2011-06-01 00:00:00

abstract：:Little is known about the morphological response of muscle after long term traction. The purpose of this study was to investigate the morphological changes of skeletal muscle during limb lengthening. After application of mini-extraskeletal fixator, the hindlimb of New Zealand white rabbit was osteotomized and then slo...

journal_title：Histology and histopathology

authors： Sun JS,Hou SM,Hang YS,Liu TK,Lu KS

更新日期：1996-04-01 00:00:00

abstract：:Studies with scanning electron microscopy in the normal human sulcular epithelium are scarce, and no precise information exists about cell surface patterns along the epithelium, the frequencies of these patterns, or possible regional differences within the mouth. In five periodontal biopsy specimens each from the ante...

journal_title：Histology and histopathology

authors： Sánchez-Quevedo MC,Moreu G,Campos A,García JM,González-Jaranay M

更新日期：1994-01-01 00:00:00

abstract：:The corneal structure of three deep-sea species of teleosts (Gadiformes, Teleostei) from different depths (250-4000 m) and photic zones are examined at the level of the light and electron microscopes. Each species shows a similar but complex arrangement of layers with a cornea split into dermal and scleral components....

journal_title：Histology and histopathology

authors： Collin SP,Collin HB

更新日期：1998-04-01 00:00:00

abstract：:Dysadherin, a cancer associated cell membrane glycoprotein, has been reported to downregulate E-cadherin. Aberrant expression of E-cadherin has been associated with the development of metastases in patients with cancer. Even though the expression of dysadherin and E-cadherin has been studied in primary non-small cell ...

journal_title：Histology and histopathology

authors： Mitselou A,Batistatou A,Nakanishi Y,Hirohashi S,Vougiouklakis T,Charalabopoulos K

更新日期：2010-10-01 00:00:00

abstract：:Dendritic cells (DCs) are the most potent antigen-presenting cells, and are regarded as "natural adjuvants" for the induction of primary T or T-dependent immunity. DCs in the peripheral sites capture and process antigens. Encounter of exogenous or endogenous stimuli mature the function of DCs, and they thus acquire T-...

journal_title：Histology and histopathology

authors： Chung NP,Chen Y,Chan VS,Tam PK,Lin CL

更新日期：2004-01-01 00:00:00

abstract：:The transport mechanism of soluble molecules throughout the interstitial matrix is closely associated with human tumor behavior in vivo. However, the examination of soluble components in histological architectures has been hampered by artifacts caused during conventional tissue preparation. In this study, the immunodi...

journal_title：Histology and histopathology

authors： Bai Y,Ohno N,Terada N,Saitoh S,Nakazawa T,Nakamura N,Katoh R,Ohno S

更新日期：2009-06-01 00:00:00

abstract：:Beta-catenin expression in small cell lung carcinomas (SCLC) was investigated by immunohistochemical method using antibodies against beta-catenin. 50 pre-treatment biopsies were examined and the relationship between beta-catenin expression and the patients' relevant clinical characteristics, response to chemotherapy, ...

journal_title：Histology and histopathology

authors： Rodríguez-Salas N,Palacios J,de Castro J,Moreno G,González-Barón M,Gamallo C

更新日期：2001-04-01 00:00:00

abstract：:The aim of the study was to estimate the significance of oxidative/nitrosative damage and expression of antioxidant enzymes in renal cell carcinomas (RCC). For this we investigated immunohistochemically six antioxidant enzymes (AOEs) including MnSOD, ECSOD, thioredoxin, thioredoxin reductase, and gammaglutamyl cystein...

journal_title：Histology and histopathology

authors： Soini Y,Kallio JP,Hirvikoski P,Helin H,Kellokumpu-Lehtinen P,Tammela TL,Peltoniemi M,Martikainen PM,Kinnula LV

更新日期：2006-02-01 00:00:00

abstract：:In the present work we analyze the cerebellum of chronic parkinsonian monkeys in order to clarify whether chronic mesencephalic depletion is associated with long term activation of the cerebellar neurons in chronic Parkinsonism. In our study, we observed a persistent activation of Purkinje cells in the cerebellum of c...

journal_title：Histology and histopathology

authors： Heman P,Barcia C,Gómez A,Ros CM,Ros-Bernal F,Yuste JE,de Pablos V,Fernandez-Villalba E,Toledo-Cárdenas MR,Herrero MT

更新日期：2012-01-01 00:00:00

abstract：:The purpose of this study was to determine the histological characteristics of a skeletal muscle reconstructed by means of the implantation of autologous adipose tissue following an experimentally-induced volumetric muscle loss. A cylindrical piece in the belly of the rat anterior tibial muscle was removed. In the hol...

journal_title：Histology and histopathology

authors： Leiva-Cepas F,Jimena I,Ruz-Caracuel I,Luque E,Villalba R,Peña-Amaro J

更新日期：2020-05-01 00:00:00

abstract：:Our study aimed to investigate the association of Pyruvate Kinase isozyme type M2 (PKM2) with radiation resistance in locally advanced cervical squamous cell carcinoma (LACSCC). We retrospectively reviewed 132 female patients who received primary radiation therapy to treat LACSCC at Federation Internationale of Gyneco...

journal_title：Histology and histopathology

authors： Zhao Y,Shen L,Chen X,Qian Y,Zhou Q,Wang Y,Li K,Liu M,Zhang S,Huang X

更新日期：2015-11-01 00:00:00

abstract：:Heterotopic ossification (HO) is a debilitating condition in which cartilage and bone forms in soft tissues such as muscle, tendon, and ligament causing immobility. This process is induced by inflammation associated with traumatic injury. In an extremely rare genetic disorder called fibrodysplasia ossificans progessiv...

journal_title：Histology and histopathology

authors： Ramirez DM,Ramirez MR,Reginato AM,Medici D

更新日期：2014-10-01 00:00:00

abstract：:Peritumoral brain edema (PTBE) is considered to be one of the main biological behaviors of brain glioma. However, the histopathological features of PTBE remain imprecisely defined. We analyzed the histopathological characteristics in the PTBE area of 22 cases of glioma. Microscopically, the pre-existing basic structur...

journal_title：Histology and histopathology

authors： Wang X,Liu X,Chen Y,Lin G,Mei W,Chen J,Liu Y,Lin Z,Zhang S

更新日期：2015-09-01 00:00:00

abstract：:PML is a tumour suppressor inactivated in Acute Promyelocytic Leukaemia (APL). PML is the essential component of a subnuclear structure called the PML nuclear body (PML-NB), which is disrupted in APL. By targeting different cellular proteins to this structure, PML can either hamper or potentiate their functions. The P...

journal_title：Histology and histopathology

authors： Salomoni P,Bellodi C

更新日期：2007-08-01 00:00:00

abstract：:Current data on the influence of neuropeptides on the growth, structure and function of cells comprising the hypothalamo-pituitary-adrenal axis were presented and discussed. The action of vasopressin, oxytocin, neurotensin, bombesin, neuropeptide Y, substance P and VIP have been evaluated. The hypothesis has been intr...

journal_title：Histology and histopathology

authors： Malendowicz LK

更新日期：1993-01-01 00:00:00

abstract：:The rapid Golgi method, combined with current optical and electronmicroscopical techniques, was used in three central gangliogliomas and in one dysplastic gangliocytoma of the cerebellum to study the morphology of ganglionic cells. Gangliogliomas were composed of bipolar, fusiform and radiate cells with dense core and...

journal_title：Histology and histopathology

authors： Ferrer I,Martí E,Guionnet N,Bella R,Serrano T,Towse J,Conesa G,Isamat F

更新日期：1990-07-01 00:00:00

abstract：:Previous studies have demonstrated a role for the beta-adrenergic system in the maturation of the fetal alveolar epithelium. Chronic blockade of beta-adrenergic binding sites has been shown to adversely effect physiologic and biochemical indices of fetal lung maturation. In the present study timed-pregnant female Spra...

journal_title：Histology and histopathology

authors： Smith DM,Sommers SS

更新日期：2002-04-01 00:00:00

abstract：:Serotonin-producing pancreatic endocrine tumours are rare neoplasms which in most cases exhibit malignant biological behaviour. These tumours, in the majority of the well-documented cases, are composed of argyrophil- and argentaffin-positive cells which contain large pleomorphic neurosecretory granules. In contrast, a...

journal_title：Histology and histopathology

authors： Kanavaros P,Hoang C,Le Bodic MF,Polivka M,Hautefeuille P

更新日期：1990-07-01 00:00:00

abstract：:The proto-oncogene, ets-1, is a transcription factor known to control the expression of a number of genes and has been postulated to play a role in cell growth, differentiation and tumour invasion. We examined 137 cases of breast carcinoma by immunohistochemistry and compared the degree of Ets-1 expression among the d...

journal_title：Histology and histopathology

authors： Katayama S,Nakayama T,Ito M,Naito S,Sekine I

更新日期：2005-01-01 00:00:00

abstract：:The integrity of the thymus during early life is necessary for a proper maturation of the neuroendocrine system, including the adrenal axis. The thymic metallopeptide thymulin seems to be a central physiologic mediator of thymus-pituitary communication. Furthermore, neonatal thymulin gene therapy has been shown to pre...

journal_title：Histology and histopathology

authors： Martines E,Reggiani PC,Schwerdt JI,Goya RG,Cónsole G

更新日期：2011-04-01 00:00:00

abstract：:Extracellular matrix of meningiomas was studied by light and electron microscopy with the aid of immunohistochemical techniques. Special attention was paid to the distribution of type I, III, IV, V collagens and laminin with a comparison between meningothelial and fibroblastic types. Connective tissue fibers and basem...

journal_title：Histology and histopathology

authors： Nitta H,Yamashima T,Yamashita J,Kubota T

更新日期：1990-07-01 00:00:00

abstract：:We review the morphofunctional characteristics of CD34+ stromal fibroblastic/fibrocytic cells (CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ SFCs: A) The confusing terms applied to this cell type, often combining the prefix CD34 with numerous names, including fibroblasts, fibrocyt...

journal_title：Histology and histopathology

authors： Díaz-Flores L,Gutiérrez R,García MP,Sáez FJ,Díaz-Flores L Jr,Valladares F,Madrid JF

更新日期：2014-07-01 00:00:00

abstract：:Thrombospondin-1 (TSP-1) is a matrix protein implicated in mechanisms of wound healing. TSP-1 contains the sequence cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) that has been shown to function primarily as a cell adhesion domain. Our laboratory has isolated a novel receptor specific for the CSVTCG adhesi...

journal_title：Histology and histopathology

authors： Roth JJ,Buckmire MA,Rolandelli RH,Granick MS,Tuszynski GP

更新日期：1998-10-01 00:00:00

abstract：:Introduction. Lichen planus (LP) is a chronic cytokine-mediated disease of possible auto-immune etiology. 25% of men have anogenital manifestations. Erosive penile LP causes a scarring phimosis of the foreskin in uncircumcised men. Mast cells as potent immune modulators have been implicated in a number of autoimmune a...

journal_title：Histology and histopathology

authors： Regauer S,Beham-Schmid C

更新日期：2014-08-01 00:00:00

abstract：:The aim of this study was to examine the effects of timolol in an experimental model of elevated intraocular pressure (IOP). Three episcleral veins of rats with normal IOP were cauterized. Three months later we examined the effects on anterograde axonal transport from the retinal ganglion cells (RGCs) to the superior ...

journal_title：Histology and histopathology

authors： Díaz F,Villena A,Moreno M,Vidal L,Parrado C,García-Campos J,de Vargas IP

更新日期：2005-10-01 00:00:00

abstract：:Detailed histomorphometric analysis of human conjunctival biopsy specimens has convincingly demonstrated that tissue remodeling of the extracellular matrix (ECM) is an essential and dynamic process associated with conjunctival scarring in ocular cicatricial pemphigoid (OCP). The conjunctival scarring often eventually ...

journal_title：Histology and histopathology

authors： Razzaque MS,Foster CS,Ahmed AR

更新日期：2001-10-01 00:00:00

abstract：:Sialoderivatives expressed in the rabbit oviduct under hormonal treatment have been investigated in situ by lectin histochemistry with a view to specifying further regional and temporal specializations which enable ampulla and isthmus to play distinct roles in the reproductive events. Application of MAL II and SNA lec...

journal_title：Histology and histopathology

authors： Gabrielli MG,Bondi AM,Materazzi G,Menghi G

更新日期：2004-10-01 00:00:00

abstract：:GLI-similar (Glis) 1-3 proteins constitute a subfamily of the Krüppel-like zinc finger transcription factors that are closely related to the Gli family. Glis1-3 play critical roles in the regulation of a number of physiological processes and have been implicated in several pathologies. Mutations in GLIS2 have been lin...

journal_title：Histology and histopathology

authors： Kang HS,ZeRuth G,Lichti-Kaiser K,Vasanth S,Yin Z,Kim YS,Jetten AM

更新日期：2010-11-01 00:00:00