Abstract：
:Extracellular matrix of meningiomas was studied by light and electron microscopy with the aid of immunohistochemical techniques. Special attention was paid to the distribution of type I, III, IV, V collagens and laminin with a comparison between meningothelial and fibroblastic types. Connective tissue fibers and basement membrane were not found among the tumor cells in the meningothelial type, but were found in the fibroblastic type. The immunolocalizations were consistently demonstrated extracellularly, but were not within the cytoplasm. Type I, III and V collagens were usually demonstrated in the fibrous septum in the meningothelial type, while they were localized among the tumor cells in the fibroblastic type. Furthermore, type IV collagen and laminin were demonstrated within the vascular walls or around the syncytium in the meningothelial type, while they were localized among the tumor cells in the fibroblastic type. In both types the expression of type IV collagen and laminin was closely related to the distribution of basement membrane. Although meningothelial and fibroblastic meningiomas showed quite different distribution of extracellular matrices, the profile of collagen types expressed by these two basic types was essentially the same. The cellular derivation of meningiomas was discussed with particular attention to the structure of human arachnoid villi and meninges.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Nitta H,Yamashima T,Yamashita J,Kubota Tsubject
Has Abstractpub_date
1990-07-01 00:00:00pages
267-74issue
3eissn
0213-3911issn
1699-5848journal_volume
5pub_type
杂志文章abstract：:In the kidney, prostaglandin (PG) E2 is the main PG, playing important roles in maintaining homeostasis or development of pathological settings. Roles of PGE2 in renal lesions remain to be clarified. The expression patterns of PGE2 synthesis enzymes such as cyclooxygenase (COX)-1, COX-2 and microsomal PGE synthase (mP...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-25.995
更新日期：2010-08-01 00:00:00
abstract：:Studies in a canine bronchogenic carcinoma model indicate that alveolar type II cells may differentiate from carcinogen-exposed epithelium of larger bronchi and generate adenocarcinomas with bronchioloalveolar and other growth patterns. In this study, we investigated whether type II cells are one of the major prolifer...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:Current data on the localization of neuropeptide Y-related peptides in the hypothalamo-pituitary-adrenal gland (HPA) axis as well as the effects of these peptides on the function of cells comprising HPA axis are presented and discussed. The action of neuropeptide Y, peptide YY, and pancreatic polypeptide on HPA axis a...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：
更新日期：1996-04-01 00:00:00
abstract：:Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive cell loss confined mostly to dopaminergic neurons of the substantia nigra. Several factors, including oxidative stress, and decreased activity of complex I mitochondrial respiratory chain, are involved in the degenerative process. Ye...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：:Experimental Doxorubicin-exposure in utero is correlated with foetal oesophageal atresia, tracheo-oesophageal fistula, axial alterations. While gastrointestinal and respiratory defects have been largely investigated, only sporadic data have been published to date on notochordal and vertebral defects. The aim of this w...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-17.31
更新日期：2002-01-01 00:00:00
abstract：:Cyclosporin A is an immunosuppressive drug, which disrupts the activation of peripheral T-lymphocyte pool and blocks the maturation of thymocytes within the thymus. Normally, thymic nonlymphoid cells provide the optimal inductive microenvironment for development of T-lymphocytes. After application of cyclosporin A the...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-13.1183
更新日期：1998-10-01 00:00:00
abstract：:The pancreatic-duct system was observed during the initial stage of type 1 diabetes in C57BL/6J mice rendered diabetic with low doses of streptozocin. Light microscopy revealed that the ducts located in close proximity to islets (islet ducts) were involved in the infiltrating process: inflammatory cells extended from ...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:The adrenal glands of lower vertebrates display a notable intermingling between steroidogenic and chromaffin tissues, which increases from Pisces to Aves. As in mammals, adrenal chromaffin cells contain and release, in addition to catecholamines, serotonin and several peptides, which may affect the secretory activity ...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-13.209
更新日期：1998-01-01 00:00:00
abstract：:Recently ultraviolet light (UV) reaching the Earth's surface has been gradually increasing in amounts by the destruction of the ozone layers. Large parts of UV are absorbed in the cornea and lens, and only a few amounts reached the retina; however, the effect on the retina is not fully elucidated. 38 rats were irradia...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:The recent discovery of nitric oxide (NO) as a biological messenger molecule with unique characteristics has opened a new field in pineal research. This free radical gas is synthesized by the enzyme nitric oxide synthase (NOS) from L-arginine. The activation of adrenoreceptors in the membrane of the pinealocytes media...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：
更新日期：1996-10-01 00:00:00
abstract：:Multilocular cystic renal cell carcinoma (MCRCC) accounts for approximately 1 to 2% of all renal tumors. This tumor is currently classified as a subtype of clear cell RCC. Clinically, the majority of these tumors are incidentally found. Macroscopically, the tumor is well demarcated and consists of various-sized cysts....
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-27.969
更新日期：2012-08-01 00:00:00
abstract：:The presence of Cajal-Retzius cells in the adult human prefrontal and visual cortices has been demonstrated with calcium binding protein immunocytochemistry and NADPH-diaphorase histochemistry. These cells expressed parvalbumin, calbindin and calretinin calcium binding proteins and displayed NADPH-diaphorase enzyme ac...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-14.487
更新日期：1999-04-01 00:00:00
abstract：:Ductular hepatocytes are observed in the livers of both experimental animals and man under various conditions of severe toxin-, carcinogen- or viral-induced hepatic injury with prominent loss of parenchymal hepatocytes. These unique hepatic epithelial cells are characterized by phenotypic traits that are intermediate ...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：
更新日期：1995-04-01 00:00:00
abstract：:We compared characteristic lesions occurring in chickens and domestic ducks naturally infected with H5N1 HPAI virus in April and May 2008. Infected chickens generally exhibited pale-green, watery diarrhoea, depression, neurological signs and cyanosis of wattles and combs, and infected ducks generally exhibited neurolo...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-26.167
更新日期：2011-02-01 00:00:00
abstract：:Bacillary angiomatosis (BA) is a reactive vasoproliferative lesion occurring almost exclusively in immunocompromised individuals in response to infection by a bacillus closely related to Rochalimaea quintana. The commonest site of involvement is the skin, in the form of multiple erythematous nodules, but bacillary ang...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：:Complex carbohydrate structures are essential molecules of infectious microbes and host cells, and are involved in cell signaling associated with inflammatory and immune responses. The uptake of mannose-tailed glycans is usually carried out by macrophages, dendritic cells (DCs), and other professional phagocytes to tr...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-24.1029
更新日期：2009-08-01 00:00:00
abstract：:The ultrastructure of four aldosterone secreting adenomas and of the adjacent zona glomerulosa has been described by the use of stereological techniques. Adenomatous cells (about 2800 microns 3 in volume) invariably displayed a striking abundance of lipid droplets, which occupied about 30% of the cytoplasm. Mitochondr...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1988-07-01 00:00:00
abstract：:To understand the role of microtubules and microfilaments in regulating endothelial monolayer integrity and repair, and since microtubules and microfilaments show some co-alignment in endothelial cells, we tested the hypothesis that microtubules organize microfilament distribution. Disruption of microtubules with colc...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-20.455
更新日期：2005-04-01 00:00:00
abstract：:The International Prognostic Index (IPI) has been the basis for determining prognosis in patients with diffuse large B-cell lymphoma (DLBCL) for the past 20 years. The utility of the IPI must be reassessed in the era of immunochemotherapy. Seven risk factors at diagnosis were identified, and a maximum of 7 points were...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-11-673
更新日期：2016-03-01 00:00:00
abstract：:The aim of the present work was to study the morphological implications between the elastin and the phenotypic expression of the vascular smooth muscle cells. For this purpose, sixty human tortuous arteries from different territories have been studied. We have measured the morphometric indexes Intimal Thickening Index...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-15.95
更新日期：2000-01-01 00:00:00
abstract：:Thrombospondin-1 (TSP-1) is a matrix protein implicated in mechanisms of wound healing. TSP-1 contains the sequence cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) that has been shown to function primarily as a cell adhesion domain. Our laboratory has isolated a novel receptor specific for the CSVTCG adhesi...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-13.967
更新日期：1998-10-01 00:00:00
abstract：:Primary cultured human salivary gland cells were transfected with ori-defective mutant DNA of SV40. Following 2-3 weeks of transfection, slowly expanding colonies consisting of small compact cells emerged, while mock-transfected cells did not grow any more and eventually entered crisis, followed by cell death. Using l...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：
更新日期：1994-10-01 00:00:00
abstract：:Sample preparation of dental tissues for quantitative electron microprobe analysis has not been critically examined because of the highly mineralized nature of these structures. The present study was designed to establish the most suitable method for the electron probe quantitative determination of calcium in human pe...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-13.109
更新日期：1998-01-01 00:00:00
abstract：:Aurora A and Aurora B are serine-threonine kinase proteins which have both been implicated in human carcinogenesis through development of aneuploidy and chromosomal instability. The aim of the study is to assess the correlation of both markers with clinical and pathological parameters in patients with bladder cancer o...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-25.1371
更新日期：2010-11-01 00:00:00
abstract：:We designed to investigate the effects of down-regulating the tumor susceptibility gene 101 (TSG101) on the proliferation and apoptosis of the human breast cancer MCF-7 cell line, and the role of the MAPK/ERK signal pathway in this process. The siRNA against TSG101 was transfected into the breast cancer MCF-7 cell lin...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-26.87
更新日期：2011-01-01 00:00:00
abstract：:Thyroid glands from 7 marmosets (Callithrix jacchus) of different age groups (newborn, 2 weeks, 2, 7, 8 and 11 months, and 8 years) were grown as organ culture according to Trowell at the medium/air interphase for 3 to 30 days. The morphology of thyroid tissue was well preserved until the end of the culture period. Ne...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：:The presence of intestinal metaplasia (IM) 11 years after selective proximal vagotomy (SPV), selective proximal vagotomy with pyloroplasty (SPV + PP) and selective vagotomy with pyloroplasty (SV + PP) was investigated in 38 consecutive patients. IM was significantly more frequent in SPV than in SV + PP, SPV + PP or in...
journal_title：Histology and histopathology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1993-04-01 00:00:00
abstract：:The bronchial-associated lymphoid tissue (BALT) is a lymphoepithelial organ, related to the immune defence of the lung and to alveolar clearance, which changes size in certain states of disease. Changes in the size of BALT were quantified and compared, and Spearman's test was used to test the relation with the bronchi...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：:This study concerns the results of penile biopsies in 50 patients aged 27 to 80, with secondary impotence removed with a biopty gun or during penile surgery. The biopty gun specimens were equally representative as the open biopsy ones. The cause and the degree of erectile dysfunction were determined by clinical and la...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:Cerebral cavernous malformations (CCMs) are described as vascular lesions consisting of endothelial-lined dilated vessels embedded in a connective tissue sheath without intervening parenchyma between them. Their anatomical connections with the normal blood vessels are still enigmatic and the fine three-dimensional (3-...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-29.1071
更新日期：2014-08-01 00:00:00
