Abstract：
:Acetylcholinesterase (AchE)-positive afferent axons in the mucosa of the cat urinary bladder were examined in the present experiments. Small-sized dorsal root ganglion cells containing AchE enzyme activity were labelled by injection of retrograde tracer (wheat germ agglutinin conjugated to enzymatically inactive horseradish peroxidase gold complex) into the bladder mucosa of adult cats. Results show that 48.9% (90/184) of the labelled ganglion cells possessed AchE enzyme activity. Following unilateral dorsal root ganglionectomy (L2-5, S1-3), a total of 6619 unmyelinated axon terminals were examined in the bladder mucosa, including 691 degenerating axon terminals. Percentages (8.;6-16.1%) of degenerating axon terminals in the ganglionectomized animals (1, 2, 3, 10 and 21 days post-operated) were significantly higher than those of controls (3.1%) and the 60-day post-operated animals (3.2%). Approximately one-half (47.9%) of the degenerating axon terminals observed in the 1-21 day post-operated animals were AchE-positive. Further examination also disclosed that the population of the intact (not affected by ganglionectomy) AchE-positive axon terminals at 60 days (59.3%) was significantly greater than that of controls (45.6%). The AchE-positive terminals containing few synaptic vesicles were significantly increased in number in the 60 day post-operated cats. In conclusion the present study demonstrates that one half of afferent axons in the mucosa were AchE-positive. The increase in AchE-positive afferent axon terminals containing few synaptic vesicles may be derived from contralateral dorsal root ganglia resulting from sprouting following dorsal root ganglionectomy.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Wakabayashi Y,Kojima Y,Makiura Y,Tomoyoshi T,Maeda Tsubject
Has Abstractpub_date
1995-07-01 00:00:00pages
523-30issue
3eissn
0213-3911issn
1699-5848journal_volume
10pub_type
杂志文章abstract：:Ultrastructural changes of the parathyroid glands of pinealectomized golden hamsters were investigated. The main changes in the parathyroid glands 1 hour and 1 day after pinealectomy compared with the control and sham-operated groups were an increase of the Golgi complexes, cisternae of the granular endoplasmic reticu...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：:Although traditionally little attention has been paid to the interplay between neurotrophins and the cell cycle, a number of recent findings suggest an important role for these growth factors in the regulation of this aspect of the cellular physiology. In this article, we review the evidence from a number of studies t...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-17.1227
更新日期：2002-10-01 00:00:00
abstract：AIMS:The expression patterns of TGFB signaling proteins, such as TGFB1/2, TGFBR1(ALK5), TGFBR2, SMAD1/2/3, SMAD2/3, SMAD4, SMAD7, and of downstream targets of TGFB signaling, CDKN1A (p21CIP1), CDKN1B (p27KIP1), MYC, CDC25A, TP53, and RELA (p65NF-kB) were investigated in gastric carcinomas and other gastric lesions. ME...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-23.1439
更新日期：2008-12-01 00:00:00
abstract：:Macrophages are important effector cells in cell-mediated immunity against intracellular infection. Among cytokines that macrophages are able to release are IL-12 and TNF alpha. IL-12 is a critical linker between the innate and adaptive cell-mediated immunity, capable of Th1 differentiation and IFN gamma release by T ...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-15.199
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-16.541
更新日期：2001-04-01 00:00:00
abstract：:Serotonin-producing pancreatic endocrine tumours are rare neoplasms which in most cases exhibit malignant biological behaviour. These tumours, in the majority of the well-documented cases, are composed of argyrophil- and argentaffin-positive cells which contain large pleomorphic neurosecretory granules. In contrast, a...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-16.883
更新日期：2001-07-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-19.701
更新日期：2004-07-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,多中心研究
doi：10.14670/HH-22.837
更新日期：2007-08-01 00:00:00
abstract：:Programmed death-ligand 1 (PD-L1) is an inhibitory transmembrane protein that can prevent autoimmune response. Upregulated PD-L1 serves as a predictive biomarker for patients who may respond well to immune checkpoint therapies. However, variable associations of PD-L1 level with prognoses have been reported. In this st...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-18-272
更新日期：2020-10-28 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-11-976
更新日期：2018-09-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-28.701
更新日期：2013-06-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-14.1241
更新日期：1999-10-01 00:00:00
abstract：:The aim of this study was to examine the effects of timolol in an experimental model of elevated intraocular pressure (IOP). Three episcleral veins of rats with normal IOP were cauterized. Three months later we examined the effects on anterograde axonal transport from the retinal ganglion cells (RGCs) to the superior ...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-20.1077
更新日期：2005-10-01 00:00:00
abstract：:One hundred and eleven pituitary glands of patients (93 males, 18 females; mean age 32 years, 5 months) who died of fully developed AIDS or ARC were examined under light microscopy with the aid of immunohistochemistry. On post mortem (p.m.) examination a wide series of multiorgan alterations was noticed. Microscopical...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-24.1213
更新日期：2009-10-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-23.77
更新日期：2008-01-01 00:00:00
abstract：:The Libyan jird (Meriones libycus) is a nocturnal Saharan Rodent submitted to a seasonal cycle of reproduction characterized by a short active period during spring and beginning of summer, and a long phase of sexual quiescence from the end of summer until the end of winter. During this cycle, the male reproductive org...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-22.603
更新日期：2007-06-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-11-811
更新日期：2017-05-01 00:00:00
abstract：:Sulfur dioxide (SO₂) is a toxic gas and air pollutant. The toxic effects of SO₂ have been extensively studied. Oxidative damage due to SO₂ can occur in multiple organs. Inhaled SO₂ can also cause chromosomal aberrations, DNA damage and gene mutations in mammals. However, SO₂ can also be generated from the sulfur-conta...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-11-904
更新日期：2017-12-01 00:00:00
abstract：:The S100 gene family, which is composed of at least 24 members carrying the Ca2+ binding EF-hand motif, has been implicated in both intracellular and extracellular functions, including enzyme activities, immune responses, cytoskeleton dynamics, Ca2+ homeostasis, cell growth and cell differentiation. Altered S100 prote...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-22.1025
更新日期：2007-09-01 00:00:00
abstract：:In the present study we examined prognostic value of immunohistochemical estimation of topoisomerase 1A (TOP 1A) and HER-2/neu expression in ovarian cancers treated with platinum-based drugs but not with topotecan and the relation between expression of these proteins on the one hand and intensity of proliferation (Ki6...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-21.713
更新日期：2006-07-01 00:00:00
abstract：:The presence of the mu-opioid receptor and the type of glycosylation in the third extra-cellular loop of this receptor was investigated in the isthmus of mare oviduct during oestrus by means of immunoblotting and immunohistochemistry combined with enzymatic (N-glycosidase F and O-glycosidase) and chemical (beta-elimin...
journal_title：Histology and histopathology
pub_type： 杂志文章
doi：10.14670/HH-23.555
更新日期：2008-05-01 00:00:00
abstract：:In the lungs, neuronal M2 muscarinic receptors limit the release of acetylcholine from postganglionic cholinergic nerves. However, these receptors are not functional under certain circumstances in animal models of hyperreactivity such as occurs after exposure of sensitised animals to an allergen or during a respirator...
journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-15.861
更新日期：2000-07-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-18-138
更新日期：2019-12-01 00:00:00
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journal_title：Histology and histopathology
pub_type： 杂志文章,评审
doi：10.14670/HH-18.879
更新日期：2003-07-01 00:00:00
