Abstract:
:The sarcolemmal domain of rat duodenal smooth muscle cells includes caveolae and associated cytoskeletal or filamentous elements. We have used the quick-freezing, deep-etching method to examine the three dimensional relationships between these components. Replica membranes for separated strips of rat duodenal muscle layers were routinely prepared after extraction soluble proteins from cytoplasm and extracellular matrix. As results, 1) cytoskeletal elements in smooth muscle cells consisted mainly of striated thin filaments; 2) thin filaments were connected with some plasma membranes through filaments associated with the sarcolemma, which formed fine network structures beneath the sarcolemma; 3) many bridging structures between the filaments associated with the sarcolemma and the extracellular matrix were frequently detected in the plasma membrane; and 4) compact filaments associated with the sarcolemma almost disappeared near the caveolae, and only thin filaments were anchored to their neck parts. The special arrangement of the cytoskeletal components, which is probably necessary for the intestinal motility, characterizes the topographical difference of the smooth muscle sarcolemma.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Takayama I,Fujii Y,Terada N,Baba T,Kato Y,Fujino MA,Ohno Sdoi
10.14670/HH-15.1059subject
Has Abstractpub_date
2000-10-01 00:00:00pages
1059-66issue
4eissn
0213-3911issn
1699-5848journal_volume
15pub_type
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