Abstract:
:The ultrastructure of the atrial myocardium in the monkey (Macaca fascicularis) was studied after bilateral cervical vagotomy and survival times of 100, 175 and 367 days. Changes were observed in the nucleus and the cytoplasm of the myocyte. Sequestered within the nuclei of the affected myocytes were cytoplasmic organelles and inclusions. In the late stages, there was a tendency towards condensation and margination of the heterochromatin. Changes in the cytoplasm included increased glycogen, mitochondrial degeneration and myofibrillar disorganisation and degeneration. There was increased collagen and mononuclear cell infiltration in the extracellular space in the later stages. This study has shown that the long term structural integrity of the atrial myocyte depends on an intact vagal innervation. The survival of the monkey after chronic bilateral vagotomy suggests that this nonhuman primate is a suitable model for functional studies of the parasympathetically denervated heart.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Wong WC,Yick TY,Ling EAsubject
Has Abstractpub_date
1989-07-01 00:00:00pages
359-66issue
3eissn
0213-3911issn
1699-5848journal_volume
4pub_type
杂志文章abstract::The transport mechanism of soluble molecules throughout the interstitial matrix is closely associated with human tumor behavior in vivo. However, the examination of soluble components in histological architectures has been hampered by artifacts caused during conventional tissue preparation. In this study, the immunodi...
journal_title:Histology and histopathology
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journal_title:Histology and histopathology
pub_type: 杂志文章,评审
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journal_title:Histology and histopathology
pub_type: 杂志文章
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journal_title:Histology and histopathology
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更新日期:1995-10-01 00:00:00
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journal_title:Histology and histopathology
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journal_title:Histology and histopathology
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journal_title:Histology and histopathology
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更新日期:2005-01-01 00:00:00
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journal_title:Histology and histopathology
pub_type: 杂志文章,多中心研究
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更新日期:2007-08-01 00:00:00
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journal_title:Histology and histopathology
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更新日期:2009-08-01 00:00:00
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journal_title:Histology and histopathology
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更新日期:2019-10-01 00:00:00