Bacillary angiomatosis. A "new" disease with a broadening clinicopathologic spectrum.

Abstract:

:Bacillary angiomatosis (BA) is a reactive vasoproliferative lesion occurring almost exclusively in immunocompromised individuals in response to infection by a bacillus closely related to Rochalimaea quintana. The commonest site of involvement is the skin, in the form of multiple erythematous nodules, but bacillary angiomatosis can also present in a wide variety of sites such as soft tissues, bone, lymph node, liver and spleen. Some patients may present with persistent fever and bacteraemia. Bacillary angiomatosis is characterized histologically by proliferation of blood vessels lined by plump endothelium, associated with an interstitial eosinophilic or amphophilic material formed by aggregated bacilli, best demonstrated by the Warthin-Starry stain. A heavy infiltrate of neutrophils is frequently, but not invariably, present. In the liver and spleen, there may be in addition features of peliosis. It is important to be able to diagnose bacillary angiomatosis correctly because prompt treatment with antibiotics is potentially life-saving.

journal_name

Histol Histopathol

authors

Tsang WY,Chan JK

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

143-52

issue

1

eissn

0213-3911

issn

1699-5848

journal_volume

7

pub_type

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