Cape Town solution in prolonged myocardial preservation: structural and ultrastructural study.

Abstract:

:This study deals with myocardial preservation after 24 hours of continuous, hypothermic and oxygenated perfusion with Cape Town (CT) solution, focusing on the morphological changes produced by preservation and reperfusion, and their possible relationship to the composition of the solution and the immediate hemodynamic findings after orthotopic heart transplantation in dogs. After preservation, aside from mild or moderate mitochondrial changes, the most relevant lesions included edema and vasoconstriction. Reperfusion was followed by the development of areas of necrosis forming contraction bands and an increment in the mitochondrial damage; the intercalated disks conserved their normal structure; edema became more prominent and was invariably accompanied by hemorrhage; vasoconstriction was very pronounced and was accompanied on occasion by evidence of capillary rupture; and inflammatory cells were observed in the interstitium. These results indicate that colloid must be added to Cape Town solution and that reperfusion probably requires selective approaches to deal with vasoconstriction and inflammation.

journal_name

Histol Histopathol

authors

García-Poblete E,Alvarez L,Fernández H,Escudero C,Torralba A

doi

10.14670/HH-13.21

subject

Has Abstract

pub_date

1998-01-01 00:00:00

pages

21-7

issue

1

eissn

0213-3911

issn

1699-5848

journal_volume

13

pub_type

杂志文章
  • Hypophyseal pathology in AIDS.

    abstract::One hundred and eleven pituitary glands of patients (93 males, 18 females; mean age 32 years, 5 months) who died of fully developed AIDS or ARC were examined under light microscopy with the aid of immunohistochemistry. On post mortem (p.m.) examination a wide series of multiorgan alterations was noticed. Microscopical...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Mosca L,Costanzi G,Antonacci C,Boldorini R,Carboni N,Cristina S,Liverani C,Parravicini C,Pirolo A,Vago L

    更新日期:1992-04-01 00:00:00

  • Immunohistochemical demonstration of metallothionein in benign and malignant canine mammary tumours.

    abstract::Immunocytochemical demonstration of metallothionein (MT) has been reported as a useful prognostic tool in human breast cancer. The aim of this study was to determine the immunohistochemical location of MT in canine mammary tumours and its possible correlation with the morphologic characteristics of these tumours. Surg...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-14.51

    authors: Fuentealba IC,Mullins JE

    更新日期:1999-01-01 00:00:00

  • Pathological changes of human unmyelinated nerve fibers: a review.

    abstract::In the cutaneous nerves, unmyelinated nerve fibers outnumber the myelinated ones but are scarcely analyzed, especially at autopsy. This indifference toward the pathology of unmyelinated nerve fibers may be due to the necessity of electron microscopic analyses and, more importantly, the obscurity of pathological altera...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-15.313

    authors: Kanda T

    更新日期:2000-01-01 00:00:00

  • Immunohistochemical expression and localization of MMP-9, MMP-13, E-Cadherin and Ki-67 in road pavers' skin chronically exposed to bitumen products.

    abstract::To investigate the matrix metalloproteinase (MMP)-9, (MMP)-13, E-Cadherin and Ki-67 expressions in road pavers' skin chronically exposed to bitumen products in order to contribute to a better understanding of the earlier tissue alteration. Skin punch biopsies from 16 daily exposed workers and a control group were stud...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-18-116

    authors: Loreto C,Lombardo C,Caltabiano R,Filetti V,Vitale E,Seminara D,Castorina S,Fenga C,Ledda C,Rapisarda V

    更新日期:2019-10-01 00:00:00

  • Role of angiogenesis on bone formation.

    abstract::Angiogenesis and bone formation are coupled during skeletal development and fracture healing. This relationship, although known for some time, has not been properly explored. Advances in the discovery of how angiogenesis is regulated in physiological processes like embryogenesis, endometrial regeneration and wound hea...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-27.559

    authors: Portal-Núñez S,Lozano D,Esbrit P

    更新日期:2012-05-01 00:00:00

  • Ultrastructural observation on the rat supraoptic neurons following acute operative stress.

    abstract::The response of the SON to various forms of stress is well documented. However, the effect of operative stress, which is a common and important clinical event requiring the mediation of vasopressin, has largely escaped attention. The present report describes the ultrastructural changes in the neurons of the caudal (re...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Ray PK,Choudhury SR

    更新日期:1988-04-01 00:00:00

  • Coexistence of serotonin and cholecystokinin in paraneurons of the foetal sheep lung.

    abstract::The coexistence of serotonin and cholecystokinin was studied in foetal sheep lungs at pseudoglandular stage of development by light microscopic immunohistochemistry. The coexistence was examined by staining consecutive sections with the different antibodies. Serotonin and cholecystokinin immunoreactivity was found wit...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Balaguer L,Romano J,Ruiz-Pesini P

    更新日期:1994-01-01 00:00:00

  • Gene therapy strategies in neurodegenerative diseases.

    abstract::Treatment of neurodegenerative diseases by classical pharmacotherapy is restricted by blood-brain barrier which prevents access to the brain of potentially therapeutic molecules. Recent progress in the knowledge of pathophysiological molecular processes, and in the development of molecular biotechnology have opened th...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-16.883

    authors: Giménez y Ribotta M

    更新日期:2001-07-01 00:00:00

  • Effects of orexins A and B on the secretory and proliferative activity of immature and regenerating rat adrenal glands.

    abstract::Orexins A and B are two hypothalamic peptides, involved in the central regulation of feeding, which act through two receptor subtypes, named OX1R and OX2R. OX1R is selective for orexin-A, and OX2R binds both orexins. We have investigated the effects of three subcutaneous injections of 10 nmol/kg body weight of orexins...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-16.713

    authors: Malendowicz LK,Jedrzejczak N,Belloni AS,Trejter M,Hochól A,Nussdorfer GG

    更新日期:2001-07-01 00:00:00

  • Localization of androgen and estrogen receptors in rat and primate tissues.

    abstract::There is now evidence that estrogens and androgens are exerting their effects in different tissues throughout the body. In order to determine the sites of action of these steroids, studies have been performed to identify at the cellular level the localization of androgen receptor (AR) and the two estrogen receptor (ER...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-15.1261

    authors: Pelletier G

    更新日期:2000-10-01 00:00:00

  • Estimation and comparison of the contents of blood group B antigens in selected human tissues by microphotometric quantification of Griffonia simplicifolia agglutinin I-B4 staining with or without prior alpha-galactosidase digestion.

    abstract::Griffonia simplicifolia agglutinin I-B4 (GSAI-B4) has broader specificity for B antigen variants and can recognize the antigens in a wide variety of human tissues. Thus, the concentration range of GSAI-B4 required for staining and the susceptibility of staining to alpha-galactosidase digestion is presumed to correlate...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Ito N,Nagaike C,Morimura Y,Hatake H

    更新日期:1997-04-01 00:00:00

  • DKC1 gene mutations in human sporadic cancer.

    abstract:INTRODUCTION:Germline mutations in the tumour suppressor gene dyskeratosis congenit 1 (DKC1) cause the cancer prone syndrome called X-linked dyskeratosis congenita. The present study aims to determine whether mutations of the DKC1 gene may also be present in frequent human sporadic cancers (breast, colon and lung cance...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-28.365

    authors: Penzo M,Casoli L,Ceccarelli C,Treré D,Ludovini V,Crinò L,Montanaro L

    更新日期:2013-03-01 00:00:00

  • A rapid intraoperative estimation of the proliferative activity in brain tumors.

    abstract::A technique for staining the nucleolar organizer regions (NORs) in tumor cells applied to smears from brain tumor biopsy specimens is described. This technique provides a rapid intraoperative evaluation of the proliferative activity in cerebral neoplasms and is a valuable complement to hematoxylineosin stained smears,...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Vaquero J,Martínez R,Arias A,Oya S

    更新日期:1991-10-01 00:00:00

  • Ecophysiological responses of the seminal vesicle of Libyan jird (Meriones libycus) to the Saharan conditions: histological, morphometric and immunohistochemical analysis.

    abstract::The Libyan jird (Meriones libycus) is a nocturnal Saharan Rodent submitted to a seasonal cycle of reproduction characterized by a short active period during spring and beginning of summer, and a long phase of sexual quiescence from the end of summer until the end of winter. During this cycle, the male reproductive org...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-22.603

    authors: Belhocine M,Gernigon-Spychalowicz T,Robert AM,Schoevaert D,Bennazzoug Y,Exbrayat JM

    更新日期:2007-06-01 00:00:00

  • Current knowledge of dystrophin and dystrophin-associated proteins in the retina.

    abstract::Dramatical development of molecular genetics has been disclosing the molecular mechanism of Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). DMD gene product, dystrophin, is a submembranous cytoskeletal protein and many dystrophin-associated proteins (DAPs) have been identified, such as utrophin,...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-15.753

    authors: Ueda H,Baba T,Ohno S

    更新日期:2000-07-01 00:00:00

  • Expression of the Shwachman-Bodian-Diamond syndrome (SBDS) protein in human pancreatic cancer and chronic pancreatitis.

    abstract:BACKGROUND:The Shwachman-Bodian-Diamond syndrome (SBDS) protein is a member of a highly conserved family which influences RNA activation and is associated with pancreatic, skeletal and bone marrow deficiencies, as well as hematological malignancies. METHODS:In this study, the expression and localization of SBDS were i...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-23.819

    authors: Kayed H,Bekasi S,Keleg S,Welsch T,Esposito I,Shimamura A,Michalski CW,Friess H,Kleeff J

    更新日期:2008-07-01 00:00:00

  • Pathological findings in a cat with cryptococcosis and feline immunodeficiency virus infection.

    abstract::This report describes the gross, histopathological, immunocytochemical and electron microscopic findings in a cat with systemic cryptococcosis and feline immunodeficiency virus (FIV) infection. Lymphadenopathy and cloudiness of leptomeninges were the major gross findings. Numerous cryptococcal yeasts were found in lym...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Ramos-Vara JA,Ferrer L,Visa J

    更新日期:1994-04-01 00:00:00

  • DEC1 expression in 1p-aberrant oligodendroglial neoplasms.

    abstract:BACKGROUND:Expression of hypoxia-related tissue factors in 1p-aberrant oligodendroglial neoplasms diminishes patient outcome. Differentiated embryo-chondrocyte expressed gene 1 (DEC1) has been described as novel hypoxia-related tissue factor. In our study, we assessed the expression of DEC1 in 1p aberrant oligodendrogl...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-20.1173

    authors: Preusser M,Birner P,Ambros IM,Ambros PF,Budka H,Harris AL,Hainfellner JA

    更新日期:2005-10-01 00:00:00

  • Histopathological changes in the eyes in systemic lupus erythematosus: an electron microscope and immunohistochemical study.

    abstract::This paper reports the histopathological findings in the eyes of a 26-year-old female patient diagnosed with systemic lupus erythematosus (SLE) with peripheral neuropathy. The patient had no significant ocular problems. She died of pneumonia after two years of suffering. The eyeballs were procured at autopsy and the r...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:10.14670/HH-20.373

    authors: Nag TC,Wadhwa S

    更新日期:2005-04-01 00:00:00

  • Hepatic response to chronic hypoxia in experimental rat model through HIF-1 alpha, activator protein-1 and NF-kappa B.

    abstract::Chronic liver diseases are commonly associated with tissue hypoxia that may cause inflammation, oxidative stress, liver cell injury and increased nuclear transcriptional regulation. The hepatic response to chronic hypoxia at the molecular level has not yet been clearly understood until now. The aim of this study is to...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Lau TY,Xiao J,Liong EC,Liao L,Leung TM,Nanji AA,Fung ML,Tipoe GL

    更新日期:2013-04-01 00:00:00

  • Odontogenic jaw cysts: light and electron microscopical investigations.

    abstract::Light and electron microscopy were used to analyze the epithelial lining of odontogenic cysts excised from edentulous regions of the jaws. Clinically, three cases were identified as keratocysts, and 21 cases as cysts other than keratocysts ("non-keratocysts"). The epithelium of the former was found to achieve keratini...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Domenici-Lombardo L,Amunni F,Bergamini M,Romagnoli P

    更新日期:1996-04-01 00:00:00

  • Oncocytic adenoma of the nasal cavity. A case report.

    abstract::The authors present a case of benign oncocytoma (oxyphil cell adenoma) of the nasal cavity in a young woman. This is the fifth case reported in that region. Immunohistochemical stains revealed positivity only for cytokeratin. ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Miracco C,Sensini I,Vessio G,Luzi P

    更新日期:1986-01-01 00:00:00

  • Morphometric study on the interhemispheric asymmetries in the Wistar rat and the effects of early experience.

    abstract::Sixty male Wistar rats were used for this experiment and assigned at random to the control group or to the stimulation method. Control rats show cerebral asymmetry with right bias at the frontal and occipital lobes. In the case of stimulated rats the differences from the occipital zone increase while those from the fr...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Isasa Chueca JA,Lahoz Gimeno M,Redondo Marco JA

    更新日期:1992-07-01 00:00:00

  • A potential ex vivo infection model of human induced pluripotent stem cell-3D organoids beyond coronavirus disease 2019.

    abstract::The novel coronavirus disease 2019 (COVID-19) outbreak began in the city of Wuhan, whereupon it rapidly spread throughout China and subsequently across the world. Rapid transmission of COVID-19 has caused wide-spread panic. Many established medications have been used to treat the disease symptoms; however, no specific...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-18-223

    authors: Zhou H,Liu LP,Fang M,Li YM,Zheng YW

    更新日期:2020-10-01 00:00:00

  • The effects of cyclophosphamide on the gonadotrophic cells of the normal rat.

    abstract::The effects of the administration of cyclophosphamide to male rats at doses of 400 mg/m2 for a period of 5 days and of 200 mg/m2 over two five-day cycles interrupted by a 21-day break reveal differences in the ultrastructural morphology of gonadotrophic cells between treated animals and normal controls. The ultrastruc...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Poblador MS,Rojas C,Raya A,Casares JA,Aparicio J,Lancho Alonso JL

    更新日期:1990-04-01 00:00:00

  • Thermotherapy for Harding-Passey melanoma: light and electron microscopic study.

    abstract::The changes of implanted Harding-Passey melanoma in C57Bl/6J mice following treatment with wholebody hyperthermia were studied. The treated tumours showed a progressive growth delay, cellular and architectural irregularities as well as cell injury characteristics. The presence of distended and irregular blood vessels,...

    journal_title:Histology and histopathology

    pub_type: 杂志文章

    doi:

    authors: Vicente V,Gómez M,Gómez S,Calderon F,Canteras M,Cremades A

    更新日期:1987-10-01 00:00:00

  • Recombinant generation of two fragments of the rat complement inhibitory factor H [FH(SCR1-7) and FH(SCR1-4)] and their structural and functional characterization in comparison to FH isolated from rat serum.

    abstract::Factor H (FH) is the predominant soluble inhibitor of the complement system. With a concentration of 200-800 microg/ml in human and rat plasma it acts as a cofactor for the soluble factor I (FI)-mediated cleavage of the component C3b to iC3b. Furthermore it competes with factor B for binding to C3b and C3(H2O) and pro...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-21.93

    authors: Demberg T,Heine I,Götze O,Altermann WW,Seliger B,Schlaf G

    更新日期:2006-01-01 00:00:00

  • Prognostic significance of PTK7 in human malignancies.

    abstract:BACKGROUND:Protein tyrosine kinase 7 (PTK7) is a member of receptor protein tyrosine kinase-like molecules, which is involved in tumorigenesis. However, the association between PTK7 expression and its pathological significance in survival prognosis remains under investigation. The purpose of this meta-analysis is to cl...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,meta分析

    doi:10.14670/HH-11-933

    authors: Chen G,Qi S,Yang X,Chen W

    更新日期:2018-04-01 00:00:00

  • Nitric oxide and nitric oxide synthase: biology, pathology, localization.

    abstract::Nitric oxide (NO) has opened a new and vigorous field of biological and clinical experimentation as evidenced presently by about one hundred original publications every week. Being a biological signal under physiological conditions, NO may be to pathologically affected tissues. Major insights into the ...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:

    authors: Wolf G

    更新日期:1997-01-01 00:00:00

  • Telocytes and lung disease.

    abstract::Telocytes (TCs) represent a new distinct type of interstitial cells found in many organs, including lungs. TCs are mainly defined by a small cellular body from which arise very long (hundreds of micrometers) extensions named telopodes. During the last years, TCs were characterized in respect with their microRNA profil...

    journal_title:Histology and histopathology

    pub_type: 杂志文章,评审

    doi:10.14670/HH-11-807

    authors: Song D,Cretoiu D,Cretoiu SM,Wang X

    更新日期:2016-12-01 00:00:00