Persistence of Cajal-Retzius cells in the adult human cerebral cortex. An immunohistochemical study.

Abstract:

:The presence of Cajal-Retzius cells in the adult human prefrontal and visual cortices has been demonstrated with calcium binding protein immunocytochemistry and NADPH-diaphorase histochemistry. These cells expressed parvalbumin, calbindin and calretinin calcium binding proteins and displayed NADPH-diaphorase enzyme activity. The three basic morphological profiles-horizontal, pyriform and multipolar-were observed. The morphologies of labelled cells resembled those of neurons observed in Golgi studies of the human cerebral cortex. The presence of calcium binding proteins and NADPH-diaphorase in these cells suggests a possible inhibitory role as GABAergic neurons. The persistence of Cajal-Retzius cells in the adult cerebral cortex supports the idea that they undergo developmental dilution rather than postnatal degeneration.

journal_name

Histol Histopathol

authors

Martín R,Gutiérrez A,Peñafiel A,Marín-Padilla M,de la Calle A

doi

10.14670/HH-14.487

subject

Has Abstract

pub_date

1999-04-01 00:00:00

pages

487-90

issue

2

eissn

0213-3911

issn

1699-5848

journal_volume

14

pub_type

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