STAT and SMAD signaling in cancer.

abstract：:In view of the limitations of conventional prognostic factors such as differentiation degree, metastatic lymph nodes, hormonal receptors and others, especially when early lesions are found, additional new markers have been studied, such as gene amplification and cell proliferation index, in order to choose the appropr...

journal_title：Histology and histopathology

authors： Sirvent JJ,Santafé M,Salvadó MT,Alvaro T,Raventós A,Palacios J

更新日期：1994-07-01 00:00:00

abstract：:We designed to investigate the effects of down-regulating the tumor susceptibility gene 101 (TSG101) on the proliferation and apoptosis of the human breast cancer MCF-7 cell line, and the role of the MAPK/ERK signal pathway in this process. The siRNA against TSG101 was transfected into the breast cancer MCF-7 cell lin...

journal_title：Histology and histopathology

authors： Zhang Y,Song M,Cui ZS,Li CY,Xue XX,Yu M,Lu Y,Zhang SY,Wang EH,Wen YY

更新日期：2011-01-01 00:00:00

abstract：:In this paper we report the first complete mapping of the pituitary in a tuna species. The various different adenohypophysis cell types of the bluefin tuna, Thunnus thynnus L. have been identified and located using different antisera against mammalian and piscine hormones and various histochemical techniques: PAS, Alc...

journal_title：Histology and histopathology

authors： Rodríguez-Gómez FJ,Rendón-Unceta MC,Piñuela C,Muñoz-Cueto JA,Jiménez-Tenorio N,Sarasquete C

更新日期：2001-04-01 00:00:00

abstract：:Sample preparation of dental tissues for quantitative electron microprobe analysis has not been critically examined because of the highly mineralized nature of these structures. The present study was designed to establish the most suitable method for the electron probe quantitative determination of calcium in human pe...

journal_title：Histology and histopathology

authors： Sánchez-Quevedo MC,Nieto-Albano OH,García JM,Gómez de Ferraris ME,Campos A

更新日期：1998-01-01 00:00:00

abstract：:Systematic studies on hepatic stellate cells and myofibroblasts have so far mainly focused on cells located in the perisinusoidal space of Disse, the so-called littoral compartment. Here, these cells play a key role for intralobular fibrogenesis and sinusoidal capillarization. However, advanced hepatic fibrosis and ci...

journal_title：Histology and histopathology

authors： Zimmermann A,Zimmermann H,Fellay M,Reichen J

更新日期：1999-07-01 00:00:00

abstract：:The techniques for light and electron microscopic radioautography developed in our laboratory are described. The outlines of the applications to various tissues and organs are also briefly summarized. First, the techniques are explained in detail. These techniques can be divided into two categories, i.e., chemical fix...

journal_title：Histology and histopathology

authors： Nagata T

更新日期：1997-10-01 00:00:00

abstract：:Versican, a large extracellular matrix proteoglycan accumulates in tumor stroma and plays a key role in both malignant transformation and tumor progression. Increased versican expression has been observed in a wide range of malignant tumors, and has been associated with both cancer relapse and poor patient outcomes in...

journal_title：Histology and histopathology

authors： Du WW,Yang W,Yee AJ

更新日期：2013-06-01 00:00:00

abstract：:High mobility group box 1 protein (HMGB1) is a non-histone chromosomal protein which is highly conserved, ubiquitous, and widely distributed. HMGB1 has multiple functions in the nucleus, including the maintenance of nucleosome structure, the regulation of gene transcription, and involvement in DNA recombination. HMBG1...

journal_title：Histology and histopathology

authors： Umahara T,Uchihara T,Koyama S,Hashimoto T,Akimoto J,Haraoka J,Iwamoto T

更新日期：2014-02-01 00:00:00

abstract：:Amyloidosis is a group of diseases characterized by the extracellular deposition of protein that contains non-branching, straight fibrils on electron microscopy (amyloid fibrils) that have a high content of beta-pleated sheet conformation. Various biochemically distinct proteins can undergo transformation into amyloid...

journal_title：Histology and histopathology

authors： Upragarin N,Landman WJ,Gaastra W,Gruys E

更新日期：2005-10-01 00:00:00

abstract：:Since endometriosis is a proliferative disease we evaluated the presence of anti-apoptotic factor (Bcl-2) and pro-apoptotic factor (Bax) in deep pelvic endometriosis. A Cross-sectional observational study was performed at Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil. Forty women aged 26 to 46 years with ...

journal_title：Histology and histopathology

authors： Abdalla Ribeiro HS,Galvāo MA,Aoki T,Aldrighi JM,Ribeiro PA

更新日期：2014-09-01 00:00:00

abstract：:The purpose of this investigation was to clarify the mechanisms of amyloid fibril formation in human lymph nodes. In our present study, amyloid deposition was observed diffusely in all compartments of the lymph nodes. The deposition form showed extremely characteristic findings in its morphological features. Namely, a...

journal_title：Histology and histopathology

authors： Dobashi M,Yuda F,Masuda A,Terashima K,Imai Y

更新日期：1986-07-01 00:00:00

abstract：:We have studied the occurrence and specific features of liver cell dysplasia (LCD) in Chinese patients showing liver cirrhosis with or without hepatocellular carcinoma (HCC). Three types of LCD (SLCD, LLCDo, LLCDe) were morphologically defined, and these types were further analyzed using karyometry, estimation of nucl...

journal_title：Histology and histopathology

authors： Zhao M,Zhang NX,Du ZY,Laissue JA,Zimmermann A

更新日期：1994-01-01 00:00:00

abstract：:In mouse embryos, the expression of Blimp1 has recently revealed a population of allocated primordial germ cell precursors 24 hours earlier than previously thought. Those 'blimped' precursors have been shown to give rise, by mitotic division, to germ cells only and no other cell lineages. Here, we try to understand th...

journal_title：Histology and histopathology

authors： Chuva de Sousa Lopes SM,Roelen BA

更新日期：2008-12-01 00:00:00

abstract：:Bacillary angiomatosis (BA) is a reactive vasoproliferative lesion occurring almost exclusively in immunocompromised individuals in response to infection by a bacillus closely related to Rochalimaea quintana. The commonest site of involvement is the skin, in the form of multiple erythematous nodules, but bacillary ang...

journal_title：Histology and histopathology

authors： Tsang WY,Chan JK

更新日期：1992-01-01 00:00:00

abstract：:Our study aimed to investigate the association of Pyruvate Kinase isozyme type M2 (PKM2) with radiation resistance in locally advanced cervical squamous cell carcinoma (LACSCC). We retrospectively reviewed 132 female patients who received primary radiation therapy to treat LACSCC at Federation Internationale of Gyneco...

journal_title：Histology and histopathology

authors： Zhao Y,Shen L,Chen X,Qian Y,Zhou Q,Wang Y,Li K,Liu M,Zhang S,Huang X

更新日期：2015-11-01 00:00:00

abstract：:Equine endometritis eosinophilica (EE) is rarely described and its diagnostic criteria are not defined. The aim of this study was to characterize histological features of EE. A data base (1995-2013) was searched for biopsies with increased eosinophils. This study included all biopsies with this diagnosis and represent...

journal_title：Histology and histopathology

authors： Grimm AL,Schoon HA,Schöniger S

更新日期：2017-11-01 00:00:00

abstract：:Hereditary hemochromatosis (HH) is an inherited iron overload disorder characterized by normal iron-driven erythropoiesis and abnormal iron metabolism, leading to excess iron deposited in parenchymal cells of liver, heart, and endocrine glands. Iron hormone, hepcidin, plays a critical role in iron homeostasis through ...

journal_title：Histology and histopathology

authors： Liu J,Pu C,Lang L,Qiao L,Abdullahi MA,Jiang C

更新日期：2016-08-01 00:00:00

abstract：:Junctional complexes such as tight junctions, adherens junctions, and desmosomes play crucial roles in the structure and function of epithelial cells. These junctions are involved in increasing cell-cell contact and as well serve as signaling centers regulating multiple functions in epithelial cells. Carcinoma cell li...

journal_title：Histology and histopathology

authors： Kim G,Rajasekaran SA,Thomas G,Rosen EA,Landaw EM,Shintaku P,Lassman C,Said J,Rajasekaran AK

更新日期：2005-01-01 00:00:00

abstract：:The mandible has a mixed embryological origin, and its growth is associated with the secondary cartilage of the condyle process (CP). In this area, growth depends on an array of intrinsic and extrinsic factors that influence protein metabolism. In the present study, we used an adolescent rat model to evaluate the grow...

journal_title：Histology and histopathology

authors： de Oliveira BC,de Oliveira F,Martini DT,Prisco CR,da Silva Riguetti MM,Liberti EA,de Campos Boldrini S

更新日期：2010-01-01 00:00:00

abstract：:Extracellular matrix of meningiomas was studied by light and electron microscopy with the aid of immunohistochemical techniques. Special attention was paid to the distribution of type I, III, IV, V collagens and laminin with a comparison between meningothelial and fibroblastic types. Connective tissue fibers and basem...

journal_title：Histology and histopathology

authors： Nitta H,Yamashima T,Yamashita J,Kubota T

更新日期：1990-07-01 00:00:00

abstract：:The pancreatic-duct system was observed during the initial stage of type 1 diabetes in C57BL/6J mice rendered diabetic with low doses of streptozocin. Light microscopy revealed that the ducts located in close proximity to islets (islet ducts) were involved in the infiltrating process: inflammatory cells extended from ...

journal_title：Histology and histopathology

authors： Papaccio G,Strate C,Linn T

更新日期：1994-07-01 00:00:00

abstract：:Beta-catenin expression in small cell lung carcinomas (SCLC) was investigated by immunohistochemical method using antibodies against beta-catenin. 50 pre-treatment biopsies were examined and the relationship between beta-catenin expression and the patients' relevant clinical characteristics, response to chemotherapy, ...

journal_title：Histology and histopathology

authors： Rodríguez-Salas N,Palacios J,de Castro J,Moreno G,González-Barón M,Gamallo C

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Gastric Cardiac Cancer (GCC) has high incidence and poor prognosis requiring early screening of high-risk populations. Minichromosome maintenance (MCM) proteins are used as diagnostic-biomarkers in many cancers but not validated for GCC. We evaluate MCM protein 2 (MCM2), comparing it with the validated marke...

journal_title：Histology and histopathology

authors： Liu M,Li JS,Tian DP,Huang B,Rosqvist S,Su M

更新日期：2013-04-01 00:00:00

abstract：:Strain injuries of tendons are the most common orthopedic injuries in athletic subjects, be they equine or human. When the tendon is suddenly damaged, an acute inflammatory phase occurs whereas its repetitive overloading may cause chronic injuries. Currently the criteria used for grading injuries are general and subje...

journal_title：Histology and histopathology

authors： Martinello T,Pascoli F,Caporale G,Perazzi A,Iacopetti I,Patruno M

更新日期：2015-08-01 00:00:00

abstract：:In this article we review immunocytochemical localization studies using a monoclonal antibody raised against the 31 kD subunit of bovine H(+)-ATPase, and indirect immunofluorescent staining. In the proximal tubules there is intense H(+)-ATPase staining along the brush borders of S1 and S2, and linear subvillar invagin...

journal_title：Histology and histopathology

authors： Bastani B

更新日期：1997-07-01 00:00:00

abstract：INTRODUCTION:It is difficult to prevent and treat intra- and peri-neural fibrosis after peripheral nerve surgery. Many authors have attempted to develop and verify the effectiveness of substances to decrease the formation of adherences in different tissues. MATERIAL AND METHODS:this study aimed to assess the effective...

journal_title：Histology and histopathology

authors： Hernández-Cortés P,Peregrina M,Aneiros-Fernández J,Tassi M,Pajares-López M,Toledo M,O'Valle F

更新日期：2010-06-01 00:00:00

abstract：:CD45RO+ T cells are referred to as memory or helper-inducer while CD45RA+ T cells are regarded as naive or suppressor-inducer T cells. The former population predominates in the peripheral blood and even more in the synovial fluid of patients with rheumatoid arthritis, to the expense of the latter population. Within th...

journal_title：Histology and histopathology

authors： Mamoune A,Durand V,Le Goff P,Pennec YL,Youinou P,Le Corre R

更新日期：2000-04-01 00:00:00

abstract：:Macrophages play important roles in host defense mechanisms. In the brain, besides microglial cells, meningeal macrophages are present. However, the pathobiological characteristics of meningeal macrophages in rats remain to be investigated. In normal meninx, immunohistochemically, macrophages reacting to CD163 (macrop...

journal_title：Histology and histopathology

authors： Yamate J,Ishimine S,Izawa T,Kumagai D,Kuwamura M

更新日期：2009-01-01 00:00:00

abstract：:Neurons of the substantia nigra show severe morphological changes in Parkinson's disease. Pathological alterations of cell bodies have been described, whereas those of neuronal processes have hardly been investigated. Golgi impregnation has been the chosen method for demonstrating neuronal processes and dendritic and ...

journal_title：Histology and histopathology

authors： Patt S,Gertz HJ,Gerhard L,Cervós-Navarro J

更新日期：1991-07-01 00:00:00

abstract：AIMS:Gastric hyperplastic polyps (GHPs) are the most common polypoid lesion of the stomach, and their malignant potential has been demonstrated. In the present study, we evaluated the mucin phenotypes of GHPs and investigated the relationships among mucin phenotypes and clinical-pathological factors, proliferative acti...

journal_title：Histology and histopathology

authors： Li J,Wu LH,Shi Y,Li HM,Song MY,Jiao YF

更新日期：2014-03-01 00:00:00