Bone marrow combined with dental bud cells promotes tooth regeneration in miniature pig model.

abstract：:Ventricular assist devices (VADs) are considered the standard of care for end-stage heart failure (HF) patients. Despite increasing confidence in the technology, evidence data, endorsement by scientific societies and guidelines, the number of implants reached a steady state and is not increasing at the expected pace. ...

journal_title：Artificial organs

authors： Barbone A,Pagliaro B,Basciu A,Iaccarino A,Droandi G,Romano G,Citterio E,Fumero A,Torracca L,Pini D

更新日期：2020-04-23 00:00:00

abstract：:An apparatus has been contructed to regulate ultrafiltration accurately during dialysis. The principle of the apparatus is that, per unit of time, exactly the same amount of dialysate is introduced into the dialyzer as is discharged from it. The apparatus consists of two isovolumetric pumps connected in line. The four...

journal_title：Artificial organs

authors： Flendrig JG,Carpay WM,Dekkers WT

更新日期：1978-05-01 00:00:00

abstract：:Methods to predict and control cardiac output (CO) accurately in total artificial heart (TAH) recipients have varied significantly in the last few decades. Early models exhibited minimal control mechanisms and involved fixed pumping parameters. Elaborate electromechanical systems that have recently evolved require int...

journal_title：Artificial organs

authors： White RK,Olsen DB

更新日期：1991-10-01 00:00:00

abstract：:Stents are small, usually metallic tubes that are intended to prop open arteries blocked with atherosclerotic plaques. While stents have been used successfully in recent years, they still suffer from failure due to development of new tissue in stented segment (restenosis). Variations in the failure rates associated wi...

journal_title：Artificial organs

authors： Frank AO,Walsh PW,Moore JE Jr

更新日期：2002-07-01 00:00:00

abstract：:We aimed to investigate whether acellular endocardium can be used as a useful biomaterial for the intima of engineered small-caliber vascular grafts. Fresh endocardium was harvested from the swine left atrium and was decellularized by digestion with the decellularization solution of Triton X-100 and SDS containing DNa...

journal_title：Artificial organs

authors： Wang F,Guan X,Wu T,Qiao J,Han Z,Wu J,Yu X,You Q

更新日期：2016-12-01 00:00:00

abstract：:Although current continuous-flow total artificial hearts (CFTAHs) are much smaller than previous models, venous kinking may still occur after device implantation, especially in smaller animals. By inserting a self-expanding stent at the site of venous narrowing in a sheep model implanted with a CFTAH, we were able to ...

journal_title：Artificial organs

authors： Tuzun E,Parnis S,Rios J,Winkler JA,Cohn WE

更新日期：2011-07-01 00:00:00

abstract：:Eight patients were studied during four sessions of acetate-free biofiltration (AFBF). AFBF is a new dialysis technique with no base replacement agents in the dialysate and with the addition in postdilution mode of bicarbonate (HCO3) solution directly into the extracorporeal blood circuit. In this study the effects on...

journal_title：Artificial organs

authors： Santoro A,Ferrari G,Spongano M,Badiali F,Zucchelli P

更新日期：1989-10-01 00:00:00

abstract：:A magnetically levitated (maglev) centrifugal blood pump (CBP), intended for use as a ventricular assist device, needs to be highly durable and reliable for long-term use without any mechanical failure. Furthermore, maglev CBPs should be small enough to be implanted into patients of various size and weight. We have de...

journal_title：Artificial organs

authors： Asama J,Shinshi T,Hoshi H,Takatani S,Shimokohbe A

更新日期：2006-03-01 00:00:00

abstract：:The maximum ventricular elastance is a reliable index for assessing the cardiac function from changes in its pressure-volume relationship. The advantage of this index is that it can represent the contractility of either unassisted hearts or native hearts assisted with rotary blood pumps. However, there are situations ...

journal_title：Artificial organs

authors： Sugai TK,Tanaka A,Yoshizawa M,Shiraishi Y,Yambe T,Nitta S,Baba A

更新日期：2010-05-01 00:00:00

abstract：:Filtration through membranes with different nominal cut-off was used for isolation of middle molecule fractions from uremic serum. Comparison was made with test substances which in gel filtration did not show a regular relationship between molecular weight and partition coefficient. The XM50 membrane (cut-off 50,000 D...

journal_title：Artificial organs

authors： Buzio C,Montagna G,Calderini C,Manari A,Migone L

更新日期：1981-01-01 00:00:00

abstract：:To evaluate the potential clinical usefulness of a modified hemoglobin, pyridoxalated hemoglobin polyoxyethylene conjugate (PHP), the hindlimb vascular bed was perfused with PHP solution while monitoring tissue oxygen tension (PtO2) in anesthetized dogs. The hindlimb region was perfused through the external iliac arte...

journal_title：Artificial organs

authors： Kida Y,Yamakawa T,Iwasaki S,Furusho N,Kadowaki Y,Iwata S,Iwashita Y,Nishi K

更新日期：1995-06-01 00:00:00

abstract：:Fibroblast cell culture was performed to evaluate cell adhesion and cell morphology on novel hydrolyzable copolymers composed of poly(D,L-lactic acid) (PDLA) macromonomer, 2-methacryloyloxyethyl phosphorylcholine (MPC), and n-butyl methacrylate. The copolymers were used as cell culture materials for regulating the int...

journal_title：Artificial organs

authors： Watanabe J,Ishihara K

更新日期：2003-03-01 00:00:00

abstract：:In an effort to improve and automate the fluid dynamic design of rotary blood pumps, a coupled computational fluid dynamics (CFD) shape optimization methodology has been developed and implemented. This program couples a finite element flow simulation with a gradient-based optimization routine to modify automatically t...

journal_title：Artificial organs

authors： Antaki JF,Ghattas O,Burgreen GW,He B

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:DALI (direct adsorption of lipids) is the first LDL-apheresis technique able to adsorb low-density lipoprotein (LDL) and lipoproteina) directly from whole blood. In the standard procedure, acid citrate dextrose (ACD-A) is used as anticoagulation and the adsorber is rinsed with a specially manufactured primin...

journal_title：Artificial organs

authors： Bosch T,Wendler T,Maschke H

更新日期：2003-06-01 00:00:00

abstract：:The compliance problem represents a major obstacle in the development of implantable blood pumps. The motor-driven pumps are enclosed in an airtight casing with gas in the motor space. The trapped gas in the motor space either increases the load on the motor during systole or impedes blood sac filling. Potential solut...

journal_title：Artificial organs

authors： Lee S,Rosenberg G,Donachy JH,Wisman CB,Pierce WS

更新日期：1984-02-01 00:00:00

abstract：:Ligament reconstruction using a tissue-engineered artificial ligament (TEAL) requires regeneration of the ligament-bone junction such that fixation devices such as screws and end buttons do not have to be used. The objective of this study was to develop a TEAL consisting of elastin-coated polydioxanone (PDS) sutures c...

journal_title：Artificial organs

authors： Hirukawa M,Katayama S,Sato T,Inoue K,Niwa K,Ito N,Hattori T,Hosoi T,Unno H,Suzuki Y,Hasegawa M,Miyamoto K,Horiuchi T

更新日期：2018-07-01 00:00:00

abstract：:Porcine endogenous retrovirus (PERV) genomes are present in all pig cells. In this retrospective study, we assessed PERV infectivity in 28 patients treated with an extracorporeal bioartificial liver (HepatAssist system) that includes a membrane device containing porcine hepatocytes. All patients tested negative for PE...

journal_title：Artificial organs

authors： Pitkin Z,Mullon C

更新日期：1999-09-01 00:00:00

abstract：:The BiVACOR is a novel rotary Biventricular Assist Device (BiVAD) undergoing development to treat global end-stage heart failure. The design includes left and right vanes positioned on a shared rotating hub to form a double-sided magnetically and hydrodynamically suspended centrifugal impeller. The performance of the ...

journal_title：Artificial organs

authors： Timms D,Fraser J,Hayne M,Dunning J,McNeil K,Pearcy M

更新日期：2008-10-01 00:00:00

abstract：:To date, single-needle (SN) hemodialysis (HD) requires a dialysis machine equipped with two blood pumps-one controlling arterial blood flow (Qb) and one controlling venous Qb. B. Braun has developed an innovative single-pump SN HD system. Therefore, usability is improved by reducing complexity. The aim of this study w...

journal_title：Artificial organs

authors： Bieser W,Welsch M,Jakob M,Meibaum J,Rodriguez DA,Wolff H,Marcelli D,Barth C

更新日期：2018-08-01 00:00:00

abstract：:Medial opening-wedge has gained popularity in comparison to other techniques of high tibial osteotomy. This technique involves the creation of a gap in the tibia. Filling the gap with autologous iliac bone graft was recommended in the classic description, to prevent complications such as correction loss or delayed bon...

journal_title：Artificial organs

authors： Zorzi AR,da Silva HG,Muszkat C,Marques LC,Cliquet A Jr,de Miranda JB

更新日期：2011-03-01 00:00:00

abstract：:A method of creating multifocal ischemia in animals leading to left ventricular (LV) functional impairment is described. In a series of 10 mongrel dogs, electrodes were implanted in multiple branches of the coronary arteries. Subsequently, in seven animals, an 800-microA anodal current was applied for 3 h repeatedly o...

journal_title：Artificial organs

authors： Polanski J,Mandell G,Wasfie T,Freed PS,Yoshizu H,Stein PD,Sabbah HN,Kantrowitz A

更新日期：1984-11-01 00:00:00

abstract：:Creating an interatrial shunt to achieve left-right flow balance and modification of the blood chambers to improve the basic performance of the device were performed in developing an eccentric roller type total artificial heart (ERTAH). Smaller blood chambers reduce friction loss and increase durability and energy eff...

journal_title：Artificial organs

authors： Wada H,Fukunaga S,Watari M,Imai K,Sakai H,Shibamura H,Sueda T,Matsuura Y

更新日期：2000-08-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are regarded as a potential autologous source for cartilage repair, because they can differentiate into chondrocytes by transforming growth factor-beta (TGF-beta) treatment under the 3-dimensional (3-D) culture condition. However, more efficient and versatile methods for chondrogenic diff...

journal_title：Artificial organs

authors： Lee HJ,Choi BH,Min BH,Son YS,Park SR

更新日期：2006-09-01 00:00:00

abstract：:Many patients who receive a prosthetic heart valve also have or acquire cardiac arrhythmias. However, most in vitro studies of prosthetic valves examine them under normal rhythms. In this study, a monoleaflet prosthetic heart valve was tested in vitro under conditions that simulated normal sinus rhythm, first degree a...

journal_title：Artificial organs

authors： Zapanta CM

更新日期：2005-08-01 00:00:00

abstract：:The aim of this work is to construct a computational fluid dynamics model capable of simulating the transient non-Newtonian process of apheresis. A Lagrangian-Eulerian model has been developed which tracks the blood particles within a two-dimensional flow configuration. Within the Eulerian method, the fluid mass and m...

journal_title：Artificial organs

authors： De Gruttola S,Boomsma K,Poulikakos D

更新日期：2005-12-01 00:00:00

abstract：:No standardized treatment algorithm exists for the management of continuous-flow left ventricular assist device (CF-LVAD)-specific infections. The aim of this systematic review and meta-analysis was to compare the outcomes of CF-LVAD-specific infections as managed by device exchange to other treatment modalities not i...

journal_title：Artificial organs

authors： Bauer TM,Choi JH,Luc JGY,Weber MP,Moncho Escrivá E,Patel S,Maynes EJ,Boyle AJ,Samuels LE,Entwistle JW,Morris RJ,Massey HT,Tchantchaleishvili V

更新日期：2019-05-01 00:00:00

abstract：:In previous studies, we presented main strategies for suspending the rotor of a mixed-flow type (centrifugal and axial) ventricular assist device (VAD), originally presented by the Institute Dante Pazzanese of Cardiology (IDPC), Brazil. Magnetic suspension is achieved by the use of a magnetic bearing architecture in w...

journal_title：Artificial organs

authors： da Silva I,Horikawa O,Cardoso JR,Camargo FA,Andrade AJ,Bock EG

更新日期：2011-05-01 00:00:00

abstract：:The PI3K/Akt signaling pathway has been implicated in playing an important role in platelet activation during hemostasis and thrombosis involving platelet-matrix interaction and platelet aggregation. Its role in non-physiological shear stress (NPSS)-induced platelet activation relevant to high-shear blood contacting m...

journal_title：Artificial organs

authors： Chen Z,Li T,Kareem K,Tran D,Griffith BP,Wu ZJ

更新日期：2019-09-01 00:00:00

abstract：:With the incidence of end-stage heart failure steadily increasing, the need for a practical total artificial heart (TAH) has never been greater. Continuous flow TAHs (CFTAH) are being developed using rotary blood pumps (RBPs), leveraging their small size, mechanical simplicity, and excellent durability. To completely ...

journal_title：Artificial organs

authors： Nestler F,Timms DL,Stevens M,Bradley AP,Wilson SJ,Kleinheyer M,Lovell N,Frazier OH,Cohn WE

更新日期：2020-06-01 00:00:00

abstract：:Continuous hemodiafiltration (CHDF) has been performed for the treatment of severe acute pancreatitis. Phospholipase A2 (PLA2) is one of the important mediators which exacerbate acute pancreatitis, but whether PLA2 can be removed by CHDF is unclear. In this study, the kinetics of group IB and group IIA PLA2 was examin...

journal_title：Artificial organs

authors： Suzuki M,Okahisa T,Sogabe M,Iwaki H,Okita Y,Ohnishi Y,Ito S

更新日期：2007-05-01 00:00:00