The BiVACOR rotary biventricular assist device: concept and in vitro investigation.

Abstract:

:The BiVACOR is a novel rotary Biventricular Assist Device (BiVAD) undergoing development to treat global end-stage heart failure. The design includes left and right vanes positioned on a shared rotating hub to form a double-sided magnetically and hydrodynamically suspended centrifugal impeller. The performance of the device was assessed in a pulsatile mock circulation loop replicating end-stage biventricular heart failure, and was shown to restore flow from pathological (2 L/min) to normal levels (5 L/min). A novel technique to balance the left/right outflow of the BiVAD was also investigated, for which a maximum relative left to right outflow differential of 1.8 L/min was achieved at normal physiologic afterloads. The in vitro results encourage device progression to in vivo animal studies. Successful development of this BiVAD will provide a suitably miniature device for patients who require biventricular assistance.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Timms D,Fraser J,Hayne M,Dunning J,McNeil K,Pearcy M

doi

10.1111/j.1525-1594.2008.00633.x

subject

Has Abstract

pub_date

2008-10-01 00:00:00

pages

816-9

issue

10

eissn

0160-564X

issn

1525-1594

pii

AOR633

journal_volume

32

pub_type

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