Development of an intravascular pumping oxygenator using a new silicone membrane.

abstract：:Molecular biology has been moving swiftly toward clarifying the entire genome of organisms, including human. The human genome efforts that promote this transaction are characterized by the large-scale, high throughput production of data about the structure of the genome of the molecular level and its computer-assisted...

journal_title：Artificial organs

authors： Matsubara K

更新日期：1996-08-01 00:00:00

abstract：:In total, 30 patients suffering from familial hypercholesterolemia, resistant to diet and lipid-lowering drugs, were treated for up to 6 years (3.6 + or - 1.6; range, 0.2-6.8 years) with low-density lipoprotein (LDL) apheresis. Three different systems were used; the dextran sulfate adsorption system (Kaneka) for 27 of...

journal_title：Artificial organs

authors： Bambauer R,Schiel R,Latza R,Klinkmann J

更新日期：1996-04-01 00:00:00

abstract：:Although extracorporeal membrane oxygenation (ECMO) improves oxygenation, pulmonary vascular resistance may be increased due to endothelial function impairment. Inhaled nitric oxide (iNO) is increasingly used for treatment of pulmonary hypertension after surgical repair of congenital heart defects, with or without ECM...

journal_title：Artificial organs

authors： Hermon M,Golej J,Burda G,Marx M,Trittenwein G,Pollak A

更新日期：1999-11-01 00:00:00

abstract：:A comparative study of the thrombogenicity of several microporous membranes was performed using an ex vivo system simulating the conditions in an artificial lung. A study of platelet adhesion and adsorbed protein layer indicated that the membranes separated into three groups. Copolyurethane membranes adsorbed very few...

journal_title：Artificial organs

authors： Knight PM,Lyman DJ

更新日期：1985-02-01 00:00:00

abstract：:In this study a highly biocompatible polymer membrane was prepared by surface modification. An artificial cornea was also developed for clinical applications. Silicone rubber (SR) membrane was grafted with hydrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA) and acrylic acid by plasma induced grafted polyme...

journal_title：Artificial organs

authors： Hsiue GH,Lee SD,Chang PC

更新日期：1996-11-01 00:00:00

abstract：:Most bioartificial liver support systems are based on hollow fiber capillaries within modified dialysis cartridges or more sophisticated bioreactor constructions. Due to their design microscopic follow-up of reorganization and growth of tissue between the hollow fibers is not possible. The SlideReactor is a simple hol...

journal_title：Artificial organs

authors： Sauer IM,Schwartlander R,Schmid J,Efimova E,Vondran FW,Kehr D,Pless G,Spinelli A,Brandenburg B,Hildt E,Neuhaus P

更新日期：2005-03-01 00:00:00

abstract：:The compliance problem represents a major obstacle in the development of implantable blood pumps. The motor-driven pumps are enclosed in an airtight casing with gas in the motor space. The trapped gas in the motor space either increases the load on the motor during systole or impedes blood sac filling. Potential solut...

journal_title：Artificial organs

authors： Lee S,Rosenberg G,Donachy JH,Wisman CB,Pierce WS

更新日期：1984-02-01 00:00:00

abstract：:A multi-compartment capillary membrane culture model with independently perfused three-dimensionally woven capillaries was developed for immobilization of hepatocytes in bioreactors. This enables spatial restructuring of cells and enhanced mass transfer performance with more efficient oxygenation and metabolite exchan...

journal_title：Artificial organs

authors： Gerlach J,Schnoy N,Smith MD,Neuhaus P

更新日期：1994-03-01 00:00:00

abstract：:Tissue engineering of cardiovascular structures represents a novel approach to improve clinical strategies in heart valve disease treatment. The aim of this study was to engineer decellularized atrioventricular heart valve neoscaffolds with an intact ultrastructure and to reseed them with umbilical cord-derived endoth...

journal_title：Artificial organs

authors： Weymann A,Radovits T,Schmack B,Li S,Korkmaz S,Soós P,Istók R,Veres G,Chaimow N,Karck M,Szabó G

更新日期：2014-07-01 00:00:00

abstract：:The aim of the study is to measure the volume of homologous blood needed for one pediatric patient during his hospital stay. Over a 4-month period, all the patients operated upon with a blood prime or requiring blood transfusion during their hospital stay were included in this study.The cardiopulmonary bypass protocol...

journal_title：Artificial organs

authors： Durandy Y

更新日期：2010-11-01 00:00:00

abstract：:Dual chamber (DC) peritoneal dialysis (PD) dialysates contain fewer glucose degradation products (GDPs), so potentially reducing advanced glycosylation end products (AGEs), which have been reported to increase inflammation and cardiovascular risk. We wished to determine whether use of DC dialysates resulted in demonst...

journal_title：Artificial organs

authors： Vareesangthip K,Vongsanim S,Fan S,Davenport A

更新日期：2020-07-09 00:00:00

abstract：:Experimental studies on the effects of scaling on the performance of centrifugal blood pumps were conducted in a closed-loop test rig. For the prototype, eight different impellers of the same outer diameter of 25 mm were tested at 1,500, 2,000, and 2,500 revolutions per minute (rpm) using blood analog as fluid medium....

journal_title：Artificial organs

authors： Wong YW,Chan WK,Yu SC,Chua LP

更新日期：2002-11-01 00:00:00

abstract：:The aim of this study is to evaluate the effect of temperature on cerebral oxygen metabolism at total body flow bypass and antegrade cerebral perfusion (ACP). Neonatal piglets were put on cardiopulmonary bypass (CPB) with the initial flow rate of 200mL/kg/min. After cooling to 18°C (n=6) or 25°C (n=7), flow was reduce...

journal_title：Artificial organs

authors： Sasaki T,Boni L,Riemer RK,Yeung JT,Ramamoorthy C,Beckman R,Gisner C,Shuttleworth P,Hanley FL,Reddy VM

更新日期：2010-11-01 00:00:00

abstract：:To assess the efficiency of respiratory gas exchange in vitro through a dialysis membrane mounted inside a flat plate Kiil dialyzer, the model reactions of hydrogen peroxide reduction by a metal ion and of the carbon dioxide precipitation in the form of a carbonate in the dialysate were used. A comparison of the rates...

journal_title：Artificial organs

authors： Zborowski M

更新日期：1983-05-01 00:00:00

abstract：:To save priming time and perform more rapid initiation of emergency cardiopulmonary bypass for acute cardiopulmonary failure, an extracorporeal circuit with a hollow-fiber oxygenator (EL-2000 for pediatric use; Kurary Co. Ltd., Osaka, Japan) was preprimed, and the gas-exchange function was evaluated after 1 year of st...

journal_title：Artificial organs

authors： Otsu T,Terasaki H,Choi H,Tajiri A,Okamoto T,Matsuyama K,Morioka T

更新日期：1992-10-01 00:00:00

abstract：:Left ventricular assist devices (LVADs) are increasingly being used as life-saving therapy in patients with end-stage heart failure. The changes in spirometry following LVAD implantation and subsequent unloading of the left ventricle and pulmonary circulation are unknown. In this study, we explored long-term changes i...

journal_title：Artificial organs

authors： Mohamedali B,Bhat G,Yost G,Tatooles A

更新日期：2015-12-01 00:00:00

abstract：:Loss of photoreceptor cells is one of the major causes of blindness. Several groups are exploring the functional replacement of photoreceptors by a retinal prosthesis. The goal of this study was to simulate the vision levels that recipients of retinal prostheses with 4 x 4, 6 x 10, and 16 x 16 electrode arrays may exp...

journal_title：Artificial organs

authors： Hayes JS,Yin VT,Piyathaisere D,Weiland JD,Humayun MS,Dagnelie G

更新日期：2003-11-01 00:00:00

abstract：:The undulation pump total artificial heart (UPTAH) is a small implantable total artificial heart. As the UPTAH generates outflow and inflow at the same time, control of the UPTAH is very difficult. Therefore suitable control methods specifically for the UPTAH should be established. Various motor control, left-right fl...

journal_title：Artificial organs

authors： Saito I,Chinzei T,Abe Y,Ishimaru M,Mochizuki S,Ono T,Isoyama T,Iwasaki K,Kouno A,Baba A,Ozeki T,Takiura K,Tohyama T,Nakagawa H,Imachi K

更新日期：2003-01-01 00:00:00

abstract：:A beta2-microglobulin (beta2M) selective adsorbent (Lixelle) for direct hemoperfusion has been used for the treatment of hemodialysis patients with the long-term complication of dialysis related amyloidosis (DRA), but there is no significant correlation between the serum level of beta2M and the occurrence of DRA. Infl...

journal_title：Artificial organs

authors： Tsuchida K,Takemoto Y,Nakamura T,Fu O,Okada C,Yamagami S,Kishimoto T

更新日期：1998-12-01 00:00:00

abstract：:As a preliminary investigation to establish a cryopreservation method suited for bioartificial livers (BALs), three-dimensional (3-D) cryopreservation experiments with fibroblasts were performed, in which the cells were firstly seeded into a porous scaffold, and the scaffold containing the cells was then cryopreserved...

journal_title：Artificial organs

authors： Miyoshi H,Ehashi T,Ohshima N,Jagawa A

更新日期：2010-07-01 00:00:00

abstract：:The objective of this study was to evaluate the hemodynamic performance and gaseous microemboli (GME) handling ability of a simulated neonatal extracorporeal life support (ECLS) circuit with an in-line continuous renal replacement therapy (CRRT) device. The circuit consisted of a Maquet RotaFlow centrifugal pump or HL...

journal_title：Artificial organs

authors： Shank KR,Profeta E,Wang S,O'Connor C,Kunselman AR,Woitas K,Myers JL,Ündar A

更新日期：2018-04-01 00:00:00

abstract：:The sensitivity of liver allografts to even minimal periods of ischemia currently limits the duration of hepatic preservation prior to liver transplantation. This study evaluates the role of activated carbon hemoperfusion (ACH) for assisting the recovery of canine livers ischemically damaged by a 20-min occlusion of t...

journal_title：Artificial organs

authors： Toledo-Pereyra LH

更新日期：1985-08-01 00:00:00

abstract：:For many years, it was thought that nonpulsatile perfusion produced physiological and circulatory abnormalities. Since 1977, Yukihiko Nosé and his colleagues have challenged this misconception. Toward that end, they did show that if a 20% higher blood flow uses more than that required for a pulsatile blood pump, then ...

journal_title：Artificial organs

authors： Nosé Y,Kawahito K,Nakazawa T

更新日期：1996-05-01 00:00:00

abstract：:The objective of this study is to compare the myocardium protective effect of Bretschneider's histidine-tryptophan-ketoglutarate (HTK) solution versus Modified St. Thomas' (STH) solution in pediatric cardiac surgery of Tetralogy of Fallot (TOF). Seventy-seven pediatric patients of TOF who received the total surgical r...

journal_title：Artificial organs

authors： Wang ZH,An Y,Du MC,Qin TJ,Liu YB,Xu HZ,Yang LQ

更新日期：2017-05-01 00:00:00

abstract：:Implantation of left ventricular assist devices typically requires cardiopulmonary bypass support, which is associated with postoperative complications. A novel suture-less inflow cannula, which can be implanted without bypass, uses mild myocardial compression to seal the interface, however, this may lead to necrosis ...

journal_title：Artificial organs

authors： Liao S,Theodoropoulos C,Blackwood KA,Woodruff MA,Gregory SD

更新日期：2018-05-01 00:00:00

abstract：:Four hundred and forty-two serum ferritin determinations were performed in 144 patients on chronic intermittent hemodialysis treatment with intravenous iron substitution and/or oral iron substitution. Iron substitution should be done individually according to regular serum ferritin determinations. Intravenous iron sub...

journal_title：Artificial organs

authors： Müller HA,Schneider H,Hövelborn U,Streicher E

更新日期：1981-05-01 00:00:00

abstract：PURPOSE:We were led to the premise that with retrograde oxygenated blood perfusion, it would be possible to perform operations on the beating heart. METHODS:The experiment consisted of two stages: procedure 1 and 2. In procedure 1, six pigs were used. Retrograde perfusion flow was controlled to be in the range of 5.0-...

journal_title：Artificial organs

authors： Tsukioka T,Tomita S,Watanabe G,Takemura H

更新日期：2004-03-01 00:00:00

abstract：:This article presents an image processing approach dedicated for a blind mobility aid facilitated through visual intracortical electrical stimulation. The method examines a display framework based on the distances related to a scene. The distances of objects to the walker are measured using a size perspective method w...

journal_title：Artificial organs

authors： Mohammadi HM,Ghafar-Zadeh E,Sawan M

更新日期：2012-07-01 00:00:00

abstract：:The combination of plasma exchange and continuous hemofiltration was applied to patients with acute liver failure, and its clinically advantageous effects were evaluated. This procedure was found to be a powerful approach in decreasing patient morbidity; however, the effect was temporary and the patients finally died....

journal_title：Artificial organs

authors： Matsubara S

更新日期：1994-05-01 00:00:00

abstract：:To perform the first experimental tests for validation of a new gear unit concept, the pump chamber, diaphragm, and pusher plate design of an orthotopic electromechanical total artificial heart (TAH) (Helmholtz Labtype) was manufactured. In its early stage of development, it provides some of the most important feature...

journal_title：Artificial organs

authors： Kaufmann R,Reul H,Rau G

更新日期：1994-07-01 00:00:00