Intravenous prostacyclin mitigates inhaled nitric oxide rebound effect: A case control study.

Abstract:

:Although extracorporeal membrane oxygenation (ECMO) improves oxygenation, pulmonary vascular resistance may be increased due to endothelial function impairment. Inhaled nitric oxide (iNO) is increasingly used for treatment of pulmonary hypertension after surgical repair of congenital heart defects, with or without ECMO. One of the main complications of its application is deterioration of oxygenation following withdrawal of iNO. To test whether intravenous prostacyclin applied prior to and during iNO withdrawal can mitigate this rebound effect, we conducted a retrospective case control study. The rebound effect was defined as a 5% decrease of oxygenation saturation within 4 h after iNO withdrawal. Twelve children suffering from pulmonary hypertension (2 after ECMO) and treated with iNO received 10 ng/kg/min prostacyclin intravenously 24 h prior to iNO withdrawal (Group 1). Twelve children treated with iNO (3 after ECMO) who received no prostacyclin prior to iNO withdrawal were matched as controls. The rebound effect occurred in 1 out of 12 children in Group 1 and in 8 out of 12 children in Group 2 (p = 0. 0039). We conclude that application of intravenous prostacyclin prior to and during iNO withdrawal may be able to mitigate the rebound effect.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Hermon M,Golej J,Burda G,Marx M,Trittenwein G,Pollak A

doi

10.1046/j.1525-1594.1999.06448.x

subject

Has Abstract

pub_date

1999-11-01 00:00:00

pages

975-8

issue

11

eissn

0160-564X

issn

1525-1594

pii

aor6448

journal_volume

23

pub_type

杂志文章
  • Surgical use of fluosol-DA in Jehovah's Witness patients.

    abstract::The effects of Fluosol-DA 20% on circulating blood cells, hemodynamic parameters, blood gases, and organs are described and compared with the results of phase I human studies and animal experiments. Bleeding of preoperative anemia and/or surgical bleeding, Fluosol-DA 20% was administered to 7 of 10 Jehovah's Witness p...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1984.tb04238.x

    authors: Ohyanagi H,Nakaya S,Okumura S,Saitoh Y

    更新日期:1984-02-01 00:00:00

  • A novel in vitro assessment of tissue valve calcification by a continuous flow type method.

    abstract::A dynamic flow type testing to study calcification was self-designed to investigate calcification in bioprosthetic heart valves. The apparatus consists of a container into which leaflets from a porcine aortic valve are placed, a chamber that contains calcium solution, and a peristaltic pump that provides a continuous ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2000.06482-2.x

    authors: Park JC,Hwang YS,Han DW,Suh H

    更新日期:2000-02-01 00:00:00

  • Experimental study of a new method for early detection of vascular access stenoses: pulse pressure analysis at hemodialysis needle.

    abstract::Hemodialysis vascular access (VA) stenosis remains a frequent complication. However, early detection is challenging and costly. The aim of this in vitro study was to assess a new detection method based on pulse pressure analysis at the hemodialysis needle. A silicon model of a radiocephalic arteriovenous fistula was b...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00772.x

    authors: Van Canneyt K,Planken RN,Eloot S,Segers P,Verdonck P

    更新日期:2010-02-01 00:00:00

  • The pivot wash in two impeller modes for the Baylor/Miwatec centrifugal blood pump.

    abstract::A centrifugal blood pump with a double pivot impeller and an eccentric inlet port is being developed as an implantable artificial heart by the Baylor College of Medicine and Miwatec Co. Ltd. Flow visualization measurements were conducted to compare the flow around the pivot for two impeller operational modes: the top ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2006.00155.x

    authors: Yamane T,Kodama T,Nishida M,Maruyama O,Yamamoto Y,Shinohara T,Motomura T,Nosé Y

    更新日期:2006-01-01 00:00:00

  • Modified DALI LDL-apheresis using trisodium citrate anticoagulation plus bicarbonate or lactate-buffered hemofiltration substitution fluids as primers.

    abstract:BACKGROUND:DALI (direct adsorption of lipids) is the first LDL-apheresis technique able to adsorb low-density lipoprotein (LDL) and lipoproteina) directly from whole blood. In the standard procedure, acid citrate dextrose (ACD-A) is used as anticoagulation and the adsorber is rinsed with a specially manufactured primin...

    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1525-1594.2003.07104.x

    authors: Bosch T,Wendler T,Maschke H

    更新日期:2003-06-01 00:00:00

  • Donkey pericardium compares favorably with commercial xenopericardia used in the manufacture of transcatheter heart valves.

    abstract::Transcatheter aortic valve implantation (TAVI) has gained considerable acceptance in the past decade due to its lower risks than conventional open-heart surgery. However, the deformation and delamination of the leaflets during the crimping procedure have raised questions about the durability and long-term serviceabili...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13503

    authors: Mao J,Rassoli A,Tong Y,Rouse EN,Le-Bel G,How D,Germain L,Fatouraee N,Zhang Z,Reed RR,Guidoin R

    更新日期:2019-10-01 00:00:00

  • Microbial and endotoxin contamination in water and dialysate in the central United States.

    abstract::The purified water supplies and randomly selected dialysates of 51 chronic and acute dialysis centers in the central United States were surveyed to assess the relative risks to dialysis patients from microbial and endotoxin contamination. A culture medium more sensitive than those generally employed in routine quality...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1990.tb01601.x

    authors: Klein E,Pass T,Harding GB,Wright R,Million C

    更新日期:1990-04-01 00:00:00

  • The compliance problem: a major obstacle in the development of implantable blood pumps.

    abstract::The compliance problem represents a major obstacle in the development of implantable blood pumps. The motor-driven pumps are enclosed in an airtight casing with gas in the motor space. The trapped gas in the motor space either increases the load on the motor during systole or impedes blood sac filling. Potential solut...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1984.tb04248.x

    authors: Lee S,Rosenberg G,Donachy JH,Wisman CB,Pierce WS

    更新日期:1984-02-01 00:00:00

  • The roles of vascular smooth muscle cells in the aortic wall thinness under prolonged continuous flow left heart bypass.

    abstract::Aortic wall thinness was one of the most characteristic changes observed in experimental animals under prolonged continuous flow left heart bypass. The goal of this study was to determine the roles of smooth muscle cells in the vascular remodeling process in cases demonstrating aortic wall thinness under prolonged con...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2003.00022.x

    authors: Mizuno T,Nishinaka T,Ohnishi H,Tatsumi E,Tsukiya T,Oshikawa M,Shioya K,Takewa Y,Homma A,Takano H,Kitamura S,Taenaka Y

    更新日期:2003-10-01 00:00:00

  • A compact highly efficient and low hemolytic centrifugal blood pump with a magnetically levitated impeller.

    abstract::A magnetically levitated (maglev) centrifugal blood pump (CBP), intended for use as a ventricular assist device, needs to be highly durable and reliable for long-term use without any mechanical failure. Furthermore, maglev CBPs should be small enough to be implanted into patients of various size and weight. We have de...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2006.00202.x

    authors: Asama J,Shinshi T,Hoshi H,Takatani S,Shimokohbe A

    更新日期:2006-03-01 00:00:00

  • Is vecuronium toxicity abolished by hemodialysis? A case report.

    abstract::Vecuronium is a curaric agent, largely used in anesthesia. Indications as to its employ in uremic patients appear to be debated because of partial renal elimination of the drug. A 52-year-old hemodialyzed woman required transplantectomy for rejection. At awakeness after general anesthesia (induced with fentanyl, propo...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2000.06496.x

    authors: Rollino C,Visetti E,Borsa S,Pignataro A,Pozzato M,Vallero A,Quarello F

    更新日期:2000-05-01 00:00:00

  • Formation of Blood Foam in the Air Trap During Hemodialysis Due to Insufficient Automatic Priming of Dialyzers.

    abstract::We were encouraged to investigate the reasons for large amounts of foam observed in bloodlines during hemodialysis (HD). Foam was visible in the venous air trap within the Artis Gambro dialysis device. Estimates of the extent of foam were graded (0-no foam, 10-extensive foam) by two persons that were blind to the type...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13070

    authors: Jonsson P,Lindmark L,Axelsson J,Karlsson L,Lundberg L,Stegmayr B

    更新日期:2018-05-01 00:00:00

  • Flow balance between the left and right cardiac output of an eccentric roller type total artificial heart.

    abstract::We have made an eccentric roller type total artificial heart (ERTAH). The ERTAH is a positive-displacement device comparable to a DeBakey roller pump. Its left and right outputs are determined by the size of its blood chambers, and the ratio of its left and right output is almost constant. We focused on an interatrial...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1999.06414.x

    authors: Wada H,Fukunaga S,Watari M,Sakai H,Sugawara Y,Ochikubo H,Imai K,Shibamura H,Orihashi K,Sueda T,Matsuura Y

    更新日期:1999-08-01 00:00:00

  • The response of articular chondrocytes to type II collagen-Au nanocomposites.

    abstract::The nanocomposites (denoted "CII-Au") of porcine type II collagen (CII) with 0.05, 0.1, 0.5, 1, or 2.5% (wt/wt) Au nanoparticles ( approximately 5 nm) were fabricated for potential use in cartilage tissue engineering. Au formed clusters on the surface of all nanocomposites and appeared to distribute along the collagen...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2007.00482.x

    authors: Hsu SH,Yen HJ,Tsai CL

    更新日期:2007-12-01 00:00:00

  • Arterial pressure: its role in perfusion and as a criterion of extracorporeal circulation adequacy.

    abstract::Thirty-five patients undergoing open-heart surgery are reported. Cardiac index, mean arterial pressure, oxygen consumption, lactate, pyruvate, and lactate excess in the blood were measured. An inverse correlation of arterial pressure with oxygen consumption and lactate excess was found during perfusion. Comparison of ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1982.tb01675.x

    authors: Osipov VP,Khodas MJ,Dementjeva II,Pjatnitskaja GKh

    更新日期:1982-08-01 00:00:00

  • Pulsatile in vitro simulation of the pediatric univentricular circulation for evaluation of cardiopulmonary assist scenarios.

    abstract::The characteristic depressed hemodynamic state and gradually declining circulatory function in Fontan patients necessitates alternative postoperative management strategies incorporating a system level approach. In this study, the single-ventricle Fontan circulation is modeled by constructing a practical in vitro bench...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00951.x

    authors: Dur O,Lara M,Arnold D,Vandenberghe S,Keller BB,DeGroff C,Pekkan K

    更新日期:2009-11-01 00:00:00

  • Can the human lumbar posterior columns be stimulated by transcutaneous spinal cord stimulation? A modeling study.

    abstract::Stimulation of different spinal cord segments in humans is a widely developed clinical practice for modification of pain, altered sensation, and movement. The human lumbar cord has become a target for modification of motor control by epidural and, more recently, by transcutaneous spinal cord stimulation. Posterior col...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2011.01213.x

    authors: Danner SM,Hofstoetter US,Ladenbauer J,Rattay F,Minassian K

    更新日期:2011-03-01 00:00:00

  • Pump power loss and heat generation in a pivot bearing-supported Gyro centrifugal pump (C1E3).

    abstract::Pump power loss is defined as input power that is not used for the output work of the pump. Less pump power loss means a higher pump efficiency. A common opinion is that the pump power loss is closely related to heat generation of the pump, which may affect not only the endurance of pump materials, but also blood dama...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1996.tb04542.x

    authors: Takami Y,Nakazawa T,Makinouchi K,Glueck J,Ohara Y,Benkowski RJ,Nosé Y

    更新日期:1996-07-01 00:00:00

  • Morphological characteristics and proliferation of keratocytes cultured under simulated microgravity.

    abstract::This study probed the changes of keratocytes cultured under simulated microgravity. Keratocytes were isolated from rabbit corneas using collagenase digestion method. Cells were seeded in a 55-mL capacity high-aspect-ratio vessel (HARV) of rotary cell culture system (RCCS) at a density of 1 x 10(4) cells/mL. Dehydrated...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2007.00440.x

    authors: Chen J,Chen R,Gao S

    更新日期:2007-09-01 00:00:00

  • Differential functional coupling between human saphenous cryoallografts and arteries: importance of the arterial type and the biomechanical parameter evaluated.

    abstract::The aim of this study was to characterize and compare human great saphenous veins (HGSVs), HGSV cryoallografts, expanded polytetrafluoroethylene (ePTFE) segments, and elastic and muscular arteries' biomechanics, so as to identify if the biomechanical coupling and the HGSV advantages with respect to ePTFE depend on the...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2007.00467.x

    authors: Bia D,Zócalo Y,Pessana F,Armentano R,Pérez H,Saldías M,Alvarez I

    更新日期:2007-11-01 00:00:00

  • Bulk mass transport limitations during high-flux hemodialysis.

    abstract::Solute clearance during high-flux hemodialysis is determined by the combined effects of solute convection and diffusion in the membrane, blood, and dialysate. Previous studies have focused almost entirely on the membrane transport phenomena, largely ignoring the potential contribution from bulk mass transport across t...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1993.tb00403.x

    authors: Zydney AL

    更新日期:1993-11-01 00:00:00

  • Hybrid assembly of metal head and femoral stem from different manufacturers during isolated acetabular revision.

    abstract::During revision of a failed acetabular component with well-fixed antiquated femoral stem, the same variant of metal head is usually not available in the inventory production. We gathered the stems retrieved from revision surgeries and tried to reassemble with the commercially available femoral heads. This study report...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2010.01015.x

    authors: Chen CF,Chen WM,Yang CT,Huang CK,Chen TH

    更新日期:2010-08-01 00:00:00

  • Gas-exchange function of a preprimed pediatric oxygenator stored for one year for emergency cardiopulmonary bypass.

    abstract::To save priming time and perform more rapid initiation of emergency cardiopulmonary bypass for acute cardiopulmonary failure, an extracorporeal circuit with a hollow-fiber oxygenator (EL-2000 for pediatric use; Kurary Co. Ltd., Osaka, Japan) was preprimed, and the gas-exchange function was evaluated after 1 year of st...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1992.tb00331.x

    authors: Otsu T,Terasaki H,Choi H,Tajiri A,Okamoto T,Matsuyama K,Morioka T

    更新日期:1992-10-01 00:00:00

  • Doppler ultrasonic detection of particulate release during hemodialysis with cellulose hollow-fiber and sorbent suspension reciprocating dialyzers.

    abstract::Doppler ultrasound is a noninvasive technique for monitoring moving objects such as flowing blood while ignoring stationary objects such as shunt tubing. A Doppler system was investigated to determine its sensitivity in detecting particulate release in blood during hemodialysis. Seven hemodialysis procedures with dogs...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1984.tb04275.x

    authors: Badylak SF,Ash SR,Thornhill JA,Carr DJ

    更新日期:1984-05-01 00:00:00

  • Ex Vivo Porcine Organ Perfusion Models as a Suitable Platform for Translational Transplant Research.

    abstract::In transplantation surgery, extending the criteria for organ donation to include organs that may have otherwise been previously discarded has provided the impetus to improve organ preservation. The traditional method of cold static storage (CS) has been tried and tested and is suitable for organs meeting standard crit...

    journal_title:Artificial organs

    pub_type: 杂志文章,评审

    doi:10.1111/aor.12865

    authors: Kumar R,Chung WY,Dennison AR,Garcea G

    更新日期:2017-09-01 00:00:00

  • PEGylated carboxyhemoglobin bovine (SANGUINATE) ameliorates myocardial infarction in a rat model.

    abstract::Artificial oxygen (O2 ) carriers were reported to be protective in ischemia/reperfusion (I/R) in various organs including the heart. In the current study, 20 rats underwent ligation (MI) of the left anterior descending artery, were treated with 10 mL/kg of PEGylated carboxyhemoglobin bovine (SANGUINATE, S+, n = 10) or...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13384

    authors: Kawaguchi AT,Salybekov AA,Yamano M,Kitagishi H,Sekine K,Tamaki T

    更新日期:2018-12-01 00:00:00

  • Restoration of muscle volume and shape induced by electrical stimulation of denervated degenerated muscles: qualitative and quantitative measurement of changes in rectus femoris using computer tomography and image segmentation.

    abstract::This study demonstrates in a novel way how volume and shape are restored to denervated degenerated muscles due to a special pattern of electrical stimulation. To this purpose, Spiral Computer Tomography (CT) and special image processing tools were used to develop a method to isolate the rectus femoris from other muscl...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2008.00610.x

    authors: Gargiulo P,Vatnsdal B,Ingvarsson P,Knútsdóttir S,Gudmundsdóttir V,Yngvason S,Helgason T

    更新日期:2008-08-01 00:00:00

  • LDL apheresis: a novel technique (LIPOCOLLECT 200).

    abstract::Therapeutic means to lower Lp(a) are limited. The most effective method to reduce plasma Lp(a) concentration significantly is therapeutic apheresis, namely, low-density lipoprotein (LDL) lipoprotein(a) (Lp(a)) apheresis. A novel technique based on reusable LDL adsorber called Lipocollect 200 (Medicollect, Rimbach, Ger...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00959.x

    authors: Stefanutti C,Di Giacomo S,Mazzarella B,Castelli A

    更新日期:2009-12-01 00:00:00

  • In Vitro Evaluation of an Alternative Neonatal Extracorporeal Life Support Circuit on Hemodynamic Performance and Bubble Trap.

    abstract::The objective of this study was to evaluate an alternative neonatal extracorporeal life support (ECLS) circuit with a RotaFlow centrifugal pump and Better-Bladder (BB) for hemodynamic performance and gaseous microemboli (GME) capture in a simulated neonatal ECLS system. The circuit consisted of a Maquet RotaFlow centr...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12748

    authors: Spencer SB,Wang S,Woitas K,Glass K,Kunselman AR,Ündar A

    更新日期:2017-01-01 00:00:00

  • Effect of a balanced biventricular bypass system on left ventricular energies.

    abstract::Left dominant biventricular failure is a common type of heart failure after cardiac surgery. We developed a biventricular bypass (BVB) system for treatment of postcardiotomy ventricular failure, and we previously reported that the clinical results of the BVB system were superior to those obtained with venoarterial byp...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1998.06015.x

    authors: Kodera K,Kitamura M,Shibuya M,Kurihara H,Koyanagi H

    更新日期:1998-09-01 00:00:00