In vitro generation of atrioventricular heart valve neoscaffolds.

abstract：:Solute clearance during high-flux hemodialysis is determined by the combined effects of solute convection and diffusion in the membrane, blood, and dialysate. Previous studies have focused almost entirely on the membrane transport phenomena, largely ignoring the potential contribution from bulk mass transport across t...

journal_title：Artificial organs

authors： Zydney AL

更新日期：1993-11-01 00:00:00

abstract：:In patients undergoing exchange-transfusion with hemoglobin (Hb)-based oxygen (O₂) carriers (HBOC), native Hb coexists with newly transfused Hb. The two Hb types share the same arterial and venous PO₂, but their affinities for O₂ vary. A simple spreadsheet model is described aiming at evaluating the contribution of ea...

journal_title：Artificial organs

authors： Samaja M,Terraneo L

更新日期：2012-02-01 00:00:00

abstract：:The Fas molecule, also designated APO-1/CD95, belongs to the tumor necrosis factor (TNF) receptor family. It is a widely expressed membrane-anchored protein that induces apoptosis by Fas/Fas ligand (Fas-L) mediation. It was reported that Fas-mediated apoptosis plays an important role in regulation of the immune system...

journal_title：Artificial organs

authors： Kawahito K,Misawa Y,Fuse K

更新日期：2000-08-01 00:00:00

abstract：:As known from patients with pulsatile ventricular assist devices (VADs), early mobilization, physical exercise, and return to normal life are essential for optimal recovery. Recently, implantable rotary pumps became available for extended left ventricular support as bridges to transplantation. Modified procedures are ...

journal_title：Artificial organs

authors： Wieselthaler GM,Schima H,Dworschak M,Quittan M,Nuhr M,Czerny M,Seebacher G,Huber L,Grimm M,Wolner E

更新日期：2001-05-01 00:00:00

abstract：:A totally implantable centrifugal artificial heart has been developed in which a pivot bearing supported centrifugal pump is used as a blood pump. The following have been adopted as blood contacting materials in our pump: titanium alloy (Ti-6A1-4V) for the housing and impeller, alumina ceramic (Al2O3) for the male piv...

journal_title：Artificial organs

authors： Takami Y,Yamane S,Makinouchi K,Niimi Y,Sueoka A,Nosé Y

更新日期：1998-09-01 00:00:00

abstract：:Veno-venous extracorporeal lung assist (ECLA) can provide sufficient gas exchange even in most severe cases of acute respiratory distress syndrome. Commercially available systems are manually controlled, although an automatically controlled ECLA could allow individualized and continuous adaption to clinical requiremen...

journal_title：Artificial organs

authors： Kopp R,Bensberg R,Stollenwerk A,Arens J,Grottke O,Walter M,Rossaint R

更新日期：2016-10-01 00:00:00

abstract：:Transplanted allogeneic marrow grafts often fail to engraft in a lethally irradiated host. Resistance to hemopoietic allograft is a complexed phenomenon involving multiple components. To study the involvement of a hemopoietic cytokine, which was known to play a role for stem cell function, we established lines of mice...

journal_title：Artificial organs

authors： Kokai Y,Kimura H,Matsuura A,Fujimoto J

更新日期：1996-08-01 00:00:00

abstract：:The development of a ventricular assist device is depicted. The seven subprograms that make up the project are described briefly. Results obtained during the clinical assay showed that the new design of the input cannula working as a false auricle provides better efficiency, as well as a certain level of autoregulatio...

journal_title：Artificial organs

authors： del Cañizo JF,Antoranz JC,Desco MM,Alvarez-Valdivielso JM,Fernandez-Caleya D,López M,Garcia-Barreno P,Duarte J

更新日期：1994-07-01 00:00:00

abstract：:The effects of pyridoxalated hemoglobin polyoxyethylene conjugate (PHP) and other hemoglobin-related substances on arterial blood pressure (ABP) and heart rate (HR) were examined. Infusion of PHP and other hemoglobin-related substances elevated ABP and increased HR. The degree of the increase in ABP and HR did not dif...

journal_title：Artificial organs

authors： Kida Y,Maeda M,Iwata S,Iwashita Y,Goto K,Nishi K

更新日期：1995-02-01 00:00:00

abstract：:Right ventricular failure is one of the most common complications encountered after left ventricular assist device implantation and heart transplantation. It has been reported to have an incidence up to 30%. It increases morbidity and short-term mortality. Impella RP is a small pump that can provide up to 4L/min of fl...

journal_title：Artificial organs

authors： Monteagudo-Vela M,Simon A,Panoulas V

更新日期：2020-05-01 00:00:00

abstract：:Changing financial incentives have strongly influenced dosing patterns of recombinant human erythropoietin (rHuEPO) since its introduction in 1989. Although guidelines for prescribing rHuEPO exist, the extent to which they are adhered to is unknown. Using a retrospective cohort observational study design, the factors ...

journal_title：Artificial organs

authors： Thamer M,Richard CM,Klinkmann J,Ivanovich P,Lang G,Cotter DJ

更新日期：2000-02-01 00:00:00

abstract：:Many patients all over the world suffer from acute wounds caused by traumas or burns. In most crucial cases, skin regeneration cannot be promoted spontaneously, and skin grafts are applied as the main treatment. However, this therapy has some drawbacks which motivate researchers to develop wound dressings. In this stu...

journal_title：Artificial organs

authors： Mohseni M,Shamloo A,Aghababaei Z,Vossoughi M,Moravvej H

更新日期：2016-08-01 00:00:00

abstract：:Experiments have been successfully performed culminating in functional, vascularized, three-dimensional cardiac muscle tissue. Past experience in tissue engineering has led us to the understanding that cell seeding density plays a critical role in the formation and function of both in vitro and in vivo engineered tiss...

journal_title：Artificial organs

authors： Birla R,Dhawan V,Huang YC,Lytle I,Tiranathanagul K,Brown D

更新日期：2008-09-01 00:00:00

abstract：:From January 1980 through December 1990, implantation of a permanent pacemaker was performed in 34 patients following open heart surgery. The patients were divided into two groups according to the clinical indications for implantation of permanent pacemakers. Group 1 (9 patients) had surgical atrioventricular block, a...

journal_title：Artificial organs

authors： Otaki M

更新日期：1993-05-01 00:00:00

abstract：:In this study two aspects of hybrid functional electrical stimulation (FES) orthoses were investigated: joint motion constraints and FES control strategies. First, the effects of joint motion constraints on the gait of normal subjects were investigated using modern motion analysis systems, including electromyogram (EM...

journal_title：Artificial organs

authors： Yang L,Granat MH,Paul JP,Condie DN,Rowley DI

更新日期：1997-03-01 00:00:00

abstract：:The present study aimed to determine the feasibility of constructing a reinforced autologous vascular graft by combining the advantages of fibrin gel as an autologous cell carrier material with the inherent mechanical strength of an integrated mesh structure. It was hypothesized that the mesh and dynamic culture condi...

journal_title：Artificial organs

authors： Tschoeke B,Flanagan TC,Cornelissen A,Koch S,Roehl A,Sriharwoko M,Sachweh JS,Gries T,Schmitz-Rode T,Jockenhoevel S

更新日期：2008-10-01 00:00:00

abstract：:The effect of blood hematocrit (HCT) on a noninvasive flow estimation algorithm was examined in a centrifugal implantable rotary blood pump (iRBP) used for ventricular assistance. An average flow estimator, based on three parameters, input electrical power, pump speed, and HCT, was developed. Data were collected in a ...

journal_title：Artificial organs

authors： Malagutti N,Karantonis DM,Cloherty SL,Ayre PJ,Mason DG,Salamonsen RF,Lovell NH

更新日期：2007-01-01 00:00:00

abstract：:Existing peritoneal dialysis (PD) solutions were formulated for the maintenance of fluid and electrolyte balance, correction of metabolic acidosis, and the removal of metabolic waste products. Solutions currently in development are designed to improve biocompatibility by neutralizing pH and reducing glucose degradatio...

journal_title：Artificial organs

authors： Martis L,Chen C,Moberly JB

更新日期：1998-01-01 00:00:00

abstract：:Oxidative stress is crucial in red blood cell (RBC) damage induced by activated neutrophils in in vitro experiments. The aim of the study was to evaluate whether the bioincompatibility phenomena occurring during hemodialysis (HD) (where neutrophil activation with increased free radical production is well documented) m...

journal_title：Artificial organs

authors： Lucchi L,Bergamini S,Botti B,Rapanà R,Ciuffreda A,Ruggiero P,Ballestri M,Tomasi A,Albertazzi A

更新日期：2000-01-01 00:00:00

abstract：:Rotary blood pumps are emerging as a viable technology for total artificial hearts, and the development of physiological control algorithms is accelerated with new evaluation environments. In this article, we present a novel hybrid mock circulation loop (HMCL) designed specifically for evaluation of rotary total artif...

journal_title：Artificial organs

authors： Nestler F,Bradley AP,Wilson SJ,Timms DL,Frazier OH,Cohn WE

更新日期：2014-09-01 00:00:00

abstract：:We have studied the cardiac beat synchronization (CBS) control for a rotary blood pump (RBP) and revealed that it can promote pulsatility and reduce cardiac load. Besides, patients with LVAD support sometimes suffer from aortic and mitral regurgitation (AR and MR). A control method for the RBP should be validated in w...

journal_title：Artificial organs

authors： Ogawa D,Kobayashi S,Yamazaki K,Motomura T,Nishimura T,Shimamura J,Tsukiya T,Mizuno T,Takewa Y,Tatsumi E,Nishinaka T

更新日期：2020-08-19 00:00:00

abstract：:The effects of Fluosol-DA 20% on circulating blood cells, hemodynamic parameters, blood gases, and organs are described and compared with the results of phase I human studies and animal experiments. Bleeding of preoperative anemia and/or surgical bleeding, Fluosol-DA 20% was administered to 7 of 10 Jehovah's Witness p...

journal_title：Artificial organs

authors： Ohyanagi H,Nakaya S,Okumura S,Saitoh Y

更新日期：1984-02-01 00:00:00

abstract：:Atrial connections in a single-unit total artificial heart (TAH) may be difficult to make because of the rigidity of the device and the fixed position of the atrial inlets. We developed a technique to separate the natural atrial borders in an experimental implantation of a unitary TAH. In this technique, the interatri...

journal_title：Artificial organs

authors： Frazier OH,Matsuwaka R,Parnis SM,Furusho N,McGee MG,Fuqua JM

更新日期：1995-08-01 00:00:00

abstract：:We compared in vitro rates of hemolysis for a recently developed centrifugal pump with a conventional roller pump (10-10-00; Stöckert, Munich, Germany). Flow rates of 0.3 L/min and 1 L/min and a pressure of 200 mm Hg were chosen to simulate conditions during neonatal extracorporeal membrane oxygenation (ECMO). There w...

journal_title：Artificial organs

authors： Moon YS,Ohtsubo S,Gomez MR,Moon JK,Nose Y

更新日期：1996-05-01 00:00:00

abstract：:A belt worn controller and lithium-ion battery pack have been developed for use with the initial clinical trials of the Jarvik 2000 heart. Patient interface considerations, safety, and simplicity were major design inputs for the system. The controller was developed using all analog technology to avoid difficulties wit...

journal_title：Artificial organs

authors： Jarvik R,Scott V,Morrow M,Takecuhi E

更新日期：1999-06-01 00:00:00

abstract：:Neurologic complications during neonatal extracorporeal life support (ECLS) are associated with significant morbidity and mortality. Gaseous microemboli (GME) in the ECLS circuit may be a possible cause. Advances in neonatal circuitry may improve hemodynamic performance and GME handling leading to reduction in patient...

journal_title：Artificial organs

authors： Glass K,Trivedi P,Wang S,Woitas K,Kunselman AR,Ündar A

更新日期：2017-04-01 00:00:00

abstract：:The limited success of cardiac stem cell therapy has lately generated discussion regarding its effectiveness. We hypothesized that immediate cell loss after intramyocardial injection significantly obscures the regenerative potential of stem cell therapy. Therefore, our aim was to assess the distribution and quantity o...

journal_title：Artificial organs

authors： Martens A,Rojas SV,Baraki H,Rathert C,Schecker N,Zweigerdt R,Schwanke K,Rojas-Hernandez S,Martin U,Saito S,Schmitto JD,Haverich A,Kutschka I

更新日期：2014-11-01 00:00:00

abstract：:This study demonstrates in a novel way how volume and shape are restored to denervated degenerated muscles due to a special pattern of electrical stimulation. To this purpose, Spiral Computer Tomography (CT) and special image processing tools were used to develop a method to isolate the rectus femoris from other muscl...

journal_title：Artificial organs

authors： Gargiulo P,Vatnsdal B,Ingvarsson P,Knútsdóttir S,Gudmundsdóttir V,Yngvason S,Helgason T

更新日期：2008-08-01 00:00:00

abstract：:Malnutrition is a common feature seen in chronic dialysis patients, and the survival rate of obese patients receiving such treatment is higher than that of lean patients. Irrespective of obesity or diabetes, dialysis patients commonly have insulin resistance, and the leading cause of death is cardiovascular (CV) disea...

journal_title：Artificial organs

authors： Tanaka S,Yano S,Sheikh AM,Nagai A,Sugimoto T

更新日期：2014-07-01 00:00:00

abstract：:We have been developing some types of microcapsule suspensions with polyurethane membranes to evaluate the absolute hemolytic characteristics of the centrifugal blood pumps used in circulatory support devices such as artificial hearts. In order to facilitate/realize hemolysis testing on centrifugal blood pumps that ha...

journal_title：Artificial organs

authors： Maruyama O,Yamaguchi K,Nishida M,Onoguchi T,Tsutsui T,Jikuya T,Yamane T

更新日期：2008-02-01 00:00:00