Development and clinical assay of the BCM ventricular assist device.

abstract：:Testing failed to detect free isocyanates in dialyzer rinses or significant levels of immunoglobulin E antibodies to isocyanate-protein conjugates in the serum of individuals reacting during hemodialysis with dialyzers containing Cuprophan membranes. Extended immunization of rabbits with Limulus lysate-reactive materi...

journal_title：Artificial organs

authors： Butcher BT,Reed MA,O'Neil CE,Leech S,Pearson FC

更新日期：1984-08-01 00:00:00

abstract：:Malfunction of bileaflet mechanical heart valves in the mitral position could either be due to patient-prosthesis mismatch (PPM) or leaflet obstruction. The aim of this article is to investigate the validity of current echocardiographic criteria used for diagnosis of mitral prosthesis malfunction, namely maximum veloc...

journal_title：Artificial organs

authors： Evin M,Guivier-Curien C,Pibarot P,Kadem L,Rieu R

更新日期：2016-05-01 00:00:00

abstract：:It has been speculated that testosterone stimulates erythropoiesis. We hypothesized that hemoglobin levels in hemodialysis (HD) patients are associated with serum testosterone concentrations. Testosterone, hemoglobin, and other biochemical parameters were measured in a representative sample of 98 chronic HD patients (...

journal_title：Artificial organs

authors： Ekart R,Taskovska M,Hojs N,Bevc S,Hojs R

更新日期：2014-07-01 00:00:00

abstract：:A method of creating multifocal ischemia in animals leading to left ventricular (LV) functional impairment is described. In a series of 10 mongrel dogs, electrodes were implanted in multiple branches of the coronary arteries. Subsequently, in seven animals, an 800-microA anodal current was applied for 3 h repeatedly o...

journal_title：Artificial organs

authors： Polanski J,Mandell G,Wasfie T,Freed PS,Yoshizu H,Stein PD,Sabbah HN,Kantrowitz A

更新日期：1984-11-01 00:00:00

abstract：:We have developed a novel method to simultaneously evaluate thromboresistance of two different types of drip chambers with a filter used in extracorporeal blood circuits for hemodialysis using canine arteriovenous shunt models. Bilateral bypasses between the femoral artery and vein on both sides of the animal were for...

journal_title：Artificial organs

authors： Yamazaki M,Kobayashi K,Mori Y,Satoh T,Kubota S

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Ventricular assist devices are gaining ground in the therapeutic treatment of chronic heart failure. These devices are sometimes used as a bridge to recovery by unloading the left ventricle (LV) and restoring its function. It is therefore important to preserve the heart muscle and apply less invasive implant...

journal_title：Artificial organs

authors： Vandenberghe S,Nishida T,Segers P,Meyns B,Verdonck P

更新日期：2004-07-01 00:00:00

abstract：:The treatment of rheumatoid arthritis remains difficult and often controversial. Plasma exchange has been advocated in some cases. In the present study 71 sessions of double filtration plasmapheresis (DFPP) were performed in 21 patients with rheumatoid arthritis in an average of 3.7 +/- 1.1 sessions per patient within...

journal_title：Artificial organs

authors： Liu JD,Zhang C,Li WS,Lun LD

更新日期：1997-02-01 00:00:00

abstract：:To remove anti-DNA antibodies from a patient's plasma with systemic lupus erythematosus (SLE), a DNA immunoadsorbent was developed by covalently coupling calf thymus DNA on activated Sepharose 4FF. Sepharose 4FF was activated with 5-norbornene-2,3-dicarboximido carbonochloridate (Cl-CO-ONB), which was proven to be a v...

journal_title：Artificial organs

authors： Kong DL,Schuett W,Boeden HF,Kunkel S,Holtz M,Matic G,Yamada R,Yu YT,Klinkmann H

更新日期：2000-11-01 00:00:00

abstract：:Continuous hemodiafiltration (CHDF) has been performed for the treatment of severe acute pancreatitis. Phospholipase A2 (PLA2) is one of the important mediators which exacerbate acute pancreatitis, but whether PLA2 can be removed by CHDF is unclear. In this study, the kinetics of group IB and group IIA PLA2 was examin...

journal_title：Artificial organs

authors： Suzuki M,Okahisa T,Sogabe M,Iwaki H,Okita Y,Ohnishi Y,Ito S

更新日期：2007-05-01 00:00:00

abstract：:The weight gain of IVOX devices removed from the first 49 human clinical trials patients after from 1 to 29 days of implantation into the venae caval blood stream has been assessed. Each patient had received sufficient systemic heparin to maintain activated clotting times between 150 and 200 s while the IVOX device wa...

journal_title：Artificial organs

authors： Imai H,Schaap RN,Mortensen JD

更新日期：1994-11-01 00:00:00

abstract：:Interest in the effects and possible mechanisms of hemodialysis on schizophrenic patients has led to a double-blind evaluation of the effects of plasmapheresis on symptoms of schizophrenia. Also, plasmapheresis was felt to be an invaluable tool for investigating the autoimmune theory of schizophrenia. Patients (n = 10...

journal_title：Artificial organs

authors： Schulz SC,van Kammen DP,Waters R,Klein HG,Balow JE,Bunney WE Jr

更新日期：1983-08-01 00:00:00

abstract：:A new intravascular pumping oxygenator (IVPO) was developed for intravascular gas exchange and circulatory assistance in critically ill patients with respiratory and circulatory failure. The IVPO utilizes new silicone hollow fibers (diameter, 1 mm; membrane width, 50 microns) and consists of two driving tubes for the ...

journal_title：Artificial organs

authors： Sueda T,Fukunaga S,Morita S,Sueshiro M,Hirai S,Okada K,Orihashi K,Matsuura Y

更新日期：1997-01-01 00:00:00

abstract：:The aims of this study were to investigate whether introducing an interphase interval (IPI) to biphasic pulses during stimulation of the dorsiflexor muscles would affect force production and to determine whether the IPI effect is dependent on electrode position. Twelve healthy volunteers participated in the study. Eac...

journal_title：Artificial organs

authors： Springer S,Braun-Benyamin O,Abraham-Shitreet C,Becher M,Laufer Y

更新日期：2014-11-01 00:00:00

abstract：:This study aimed to clarify the role of peritoneal T-lymphocytes in peritoneal immune defense mechanisms. This study was designed to examine the changes in T-cell subpopulations during peritonitis in patients treated with continuous ambulatory peritoneal dialysis (CAPD). Our observations were correlated to responses t...

journal_title：Artificial organs

authors： Griveas I,Fleva A,Karanikas E,Gogos K,Sakellariou G

更新日期：2009-12-01 00:00:00

abstract：:Four methods of cleaning hollow-fiber artificial kidneys (HFAKs) for reuse were compared in a prospective study. Each cleaning method was randomly assigned and HFAKs were reused until volume loss was greater than or equal to 15 ml, unless discarded for other reasons. HFAKs cleaned with 0.3 M sodium hydroxide averaged ...

journal_title：Artificial organs

authors： Dennis MB Jr,Vizzo JE,Cole JJ,Westendorf DL,Ahmad S

更新日期：1986-12-01 00:00:00

abstract：:This study probed the changes of keratocytes cultured under simulated microgravity. Keratocytes were isolated from rabbit corneas using collagenase digestion method. Cells were seeded in a 55-mL capacity high-aspect-ratio vessel (HARV) of rotary cell culture system (RCCS) at a density of 1 x 10(4) cells/mL. Dehydrated...

journal_title：Artificial organs

authors： Chen J,Chen R,Gao S

更新日期：2007-09-01 00:00:00

abstract：:Aortic wall thinness was one of the most characteristic changes observed in experimental animals under prolonged continuous flow left heart bypass. The goal of this study was to determine the roles of smooth muscle cells in the vascular remodeling process in cases demonstrating aortic wall thinness under prolonged con...

journal_title：Artificial organs

authors： Mizuno T,Nishinaka T,Ohnishi H,Tatsumi E,Tsukiya T,Oshikawa M,Shioya K,Takewa Y,Homma A,Takano H,Kitamura S,Taenaka Y

更新日期：2003-10-01 00:00:00

abstract：:Percutaneous pulmonary valve implantation is a potential treatment for right ventricular outflow tract (RVOT) dysfunction. However, RVOT implantation site varies among subjects and the success of the procedure depends on RVOT morphology selection. The aim of this study was to use in vitro testing to establish percutan...

journal_title：Artificial organs

authors： Vismara R,Laganà K,Migliavacca F,Schievano S,Coats L,Taylor A,Bonhoeffer P

更新日期：2009-01-01 00:00:00

abstract：:Present-day computational fluid dynamics (CFD) techniques can be used to analyze the behavior of fluid flow in a variety of pumps. CFD can be a powerful tool during the design stage for rapid virtual prototyping of different designs, analyzing performance parameters, and making design improvements. Computational flow ...

journal_title：Artificial organs

authors： Sukumar R,Athavale MM,Makhijani VB,Przekwas AJ

更新日期：1996-06-01 00:00:00

abstract：:The cochlea is an end organ, which is metabolically dependent on a nutrient and oxygen supply to maintain its normal physiological function. Cochlear ischemia and reperfusion (IR) injury is considered one of the most important causes of human idiopathic sudden sensorineural hearing loss. The aim of the present study w...

journal_title：Artificial organs

authors： Onal M,Elsurer C,Selimoglu N,Yilmaz M,Erdogan E,Bengi Celik J,Kal O,Onal O

更新日期：2017-08-01 00:00:00

abstract：:This article describes two ongoing numerical studies of fluid-structure interaction in the cardiovascular system: an idealized pulsatile ventricular assist device (VAD), consisting of two fluid chambers separated by a flexible diaphragm; and blood flow and heart wall motion during passive filling of a canine heart. Si...

journal_title：Artificial organs

authors： Doyle MG,Vergniaud JB,Tavoularis S,Bourgault Y

更新日期：2008-11-01 00:00:00

abstract：:The flow of blood as a viscous, Newtonian, incompressible liquid in an expanding spherical cavity with a ball-type inlet valve was examined. This type of flow can serve as a model of the phase of ventricular diastole in a sac-type artificial heart. The critical values of Reynolds numbers at which flow interruption beh...

journal_title：Artificial organs

authors： Starobin IM,Zaĭko VM

更新日期：1983-02-01 00:00:00

abstract：:The objective of our study was to investigate chondrogenesis potential of human adipose-derived mesenchymal stromal cells (MSCs), using as a positive control a human source of cartilage-derived progenitor cells (PCs). This source of PCs was recently described by our group and dwells on the surface of nasoseptal cartil...

journal_title：Artificial organs

authors： Baptista LS,Silva KR,Pedrosa CS,Amaral RJ,Belizário JV,Borojevic R,Granjeiro JM

更新日期：2013-12-01 00:00:00

abstract：:The DexAide right ventricular assist device (RVAD) has been developed to provide an implantable RVAD option to surgeons. The aim of this study was to determine the optimal cannula design and optimal implantation location of the DexAide RVAD in preparation for its clinical use. Separately, a HeartMate XVE left ventricu...

journal_title：Artificial organs

authors： Ootaki Y,Ootaki C,Kamohara K,Akiyama M,Cingoz F,Kopcak MW Jr,Dessoffy R,Liu J,Massiello A,Horvath D,Chen JF,Zhou Q,Benefit S,Golding LA,Fukamachi K

更新日期：2007-08-01 00:00:00

abstract：:The nanocomposites (denoted "CII-Au") of porcine type II collagen (CII) with 0.05, 0.1, 0.5, 1, or 2.5% (wt/wt) Au nanoparticles ( approximately 5 nm) were fabricated for potential use in cartilage tissue engineering. Au formed clusters on the surface of all nanocomposites and appeared to distribute along the collagen...

journal_title：Artificial organs

authors： Hsu SH,Yen HJ,Tsai CL

更新日期：2007-12-01 00:00:00

abstract：:The abdominal left ventricular assist device (ALVAD) is an order of magnitude more effective than conventional intra-aortic balloon pumping (IABP) in unloading and providing circulatory support to the failing left ventricle. This is a report of a unique case which demonstrates that in the absence of pulmonary vascular...

journal_title：Artificial organs

authors： Norman JC,Dacso CC,Reul GJ,Massin EK,Klima T,Kahan BD,Keiser JT,Cooley DA

更新日期：1978-11-01 00:00:00

abstract：:The energy dissipated in blood or on a total artificial heart (TAH) chamber's elements directly or indirectly decreases the biological or technical safety of the TAH's work. The energetic analysis of the Polish total artificial heart (POLTAH) external work with the objective of estimating the valve and membrane roles ...

journal_title：Artificial organs

authors： Nawrat Z,Malota Z

更新日期：1998-10-01 00:00:00

abstract：:Ventricular assist devices have been shown to be effective in advanced heart failure selected patients. They often have borderline end-organ function, what facilitates organ dysfunction. Liver failure is difficult to manage and leads to increased morbidity and mortality. We report a case of ductular cholestasis, an un...

journal_title：Artificial organs

authors： Mohedano-Gómez A,Pérez-Vela JL,Renes-Carreño E,De-Andrés CI,Corres-Peiretti MA,Arribas-López P,Gutierrez-Rodriguez J,Perales-Rodríguez-De-Viguri N

更新日期：2010-02-01 00:00:00

abstract：:The aim of the study is to measure the volume of homologous blood needed for one pediatric patient during his hospital stay. Over a 4-month period, all the patients operated upon with a blood prime or requiring blood transfusion during their hospital stay were included in this study.The cardiopulmonary bypass protocol...

journal_title：Artificial organs

authors： Durandy Y

更新日期：2010-11-01 00:00:00

abstract：:Extracorporeal human lymphatic organs are expected to be excellent tools in the study of human molecular and cellular bases of the immunologic balance and tissue harmony. A rational approach and process to design a device and a procedure to recreate the human lymph node environment in vitro is described with emphasis ...

journal_title：Artificial organs

authors： Giese C,Demmler CD,Ammer R,Hartmann S,Lubitz A,Miller L,Müller R,Marx U

更新日期：2006-10-01 00:00:00