Abstract:
:In patients undergoing exchange-transfusion with hemoglobin (Hb)-based oxygen (O₂) carriers (HBOC), native Hb coexists with newly transfused Hb. The two Hb types share the same arterial and venous PO₂, but their affinities for O₂ vary. A simple spreadsheet model is described aiming at evaluating the contribution of each Hb type to the overall O₂ transport characteristics as a function of the batch Hb concentration and O₂ affinity in the HBOC solution, of the fraction of exchange-transfused blood/HBOC, and of the arterial PO₂. This model helps to yield a quantitative estimate of how tissues with high or low O₂ extraction respond to the changes cited above. The results show that the higher the exchange-transfusion ratio, the O₂ transport to tissues becomes progressively impaired. However, this effect is more critical at low batch Hb concentration and high O₂ affinity of the HBOC, especially for tissues/organs with high O₂ extraction, whereas the arterial PO₂ does not appear as critical.
journal_name
Artif Organsjournal_title
Artificial organsauthors
Samaja M,Terraneo Ldoi
10.1111/j.1525-1594.2011.01296.xsubject
Has Abstractpub_date
2012-02-01 00:00:00pages
210-5issue
2eissn
0160-564Xissn
1525-1594journal_volume
36pub_type
杂志文章abstract::Therapeutic means to lower Lp(a) are limited. The most effective method to reduce plasma Lp(a) concentration significantly is therapeutic apheresis, namely, low-density lipoprotein (LDL) lipoprotein(a) (Lp(a)) apheresis. A novel technique based on reusable LDL adsorber called Lipocollect 200 (Medicollect, Rimbach, Ger...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2009.00959.x
更新日期:2009-12-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2008.00633.x
更新日期:2008-10-01 00:00:00
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journal_title:Artificial organs
pub_type: 临床试验,杂志文章
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更新日期:1997-01-01 00:00:00
abstract::The aim of the present study was to compare the effects of ProTaper Gold, WaveOne Gold, ProTaper Universal, and WaveOne instruments on the amount of apically extruded debris. Eighty mandibular premolar teeth with straight root canals were selected and assigned to four groups (n = 20). The root canals were instrumented...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12675
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journal_title:Artificial organs
pub_type: 杂志文章
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1987.tb02622.x
更新日期:1987-02-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2003.07132.x
更新日期:2003-07-01 00:00:00
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journal_title:Artificial organs
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更新日期:1997-01-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
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更新日期:2015-12-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12294
更新日期:2014-12-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1995.tb02409.x
更新日期:1995-07-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1992.tb00537.x
更新日期:1992-08-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2006.00233.x
更新日期:2006-05-01 00:00:00
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journal_title:Artificial organs
pub_type: 临床试验,杂志文章
doi:10.1111/j.1525-1594.1995.tb02432.x
更新日期:1995-08-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12771
更新日期:2017-05-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1987.tb02667.x
更新日期:1987-06-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2009.00824.x
更新日期:2010-03-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12748
更新日期:2017-01-01 00:00:00
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更新日期:2000-06-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1984.tb04247.x
更新日期:1984-02-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章,评审
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journal_title:Artificial organs
pub_type: 杂志文章
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更新日期:1999-04-01 00:00:00
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journal_title:Artificial organs
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更新日期:2004-07-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.1998.05074.x
更新日期:1998-10-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
abstract::Individualized short hemodialysis treatment schedules, approximately three 3-h treatments per week, were introduced in a nephrology unit in 1976. In May 1985, 259 patients had been treated, which corresponds to approximately 60 new patients per million inhabitants per year. Ages at start of therapy ranged between 17 a...
journal_title:Artificial organs
pub_type: 杂志文章
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更新日期:1986-06-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13524
更新日期:2019-12-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2000.06482-2.x
更新日期:2000-02-01 00:00:00
abstract::Renal Solutions Allient Sorbent Hemodialysis System utilizes a two-chambered pneumatic pump (Pulsar Blood Pump, Renal Solutions, Inc., Warrendale, PA, USA) to avoid limitations associated with peristaltic pumping systems. Single-needle access is enabled by counter-pulsing the two pump chambers, thereby obviating compl...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2009.00724.x
更新日期:2009-04-01 00:00:00