Paracorporeal assistance system for restoring cardiac activity.

Abstract:

:Two series of experiments were conducted to assess the potential of artificial ventricular bypass in restoring cardiac activity. One series evaluated use of a paracorporeal left ventricle in 17 calves; the other evaluated biventricular bypass in 11 calves. Module pumps with a seamless blood chamber of polyurethane were used. Pump function and system parameters were controlled by a Sinus VK-2 control system. Assisted perfusion began with the induction of ventricular fibrillation. The experiments showed that left ventricular bypass was an effective method for long-term maintenance of the hemodynamics during fibrillation, leading to certain biochemical corrections and restored electrical activity and myocardial contractile function. The hemodynamic state was maintained at a higher level with biventricular bypass and was accompanied by a greater percentage of restored myocardial function. Uneven restoration of contractile activity in the left and right ventricles points to the need for adequate support of both ventricles.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Tolpekin VE,Koblov LF,Kuvaev AE,Gasanov EK

doi

10.1111/j.1525-1594.1987.tb02622.x

subject

Has Abstract

pub_date

1987-02-01 00:00:00

pages

26-30

issue

1

eissn

0160-564X

issn

1525-1594

journal_volume

11

pub_type

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