Hemolysis Related to Turbulent Eddy Size Distributions Using Comparisons of Experiments to Computations.

Abstract:

:Turbulent blood flow in medical devices contributes to blood trauma, yet the exact mechanism(s) have not been fully elucidated. Local turbulent stresses, viscous stresses, and the rate of dissipation of the turbulent kinetic energy have been proffered as hypotheses to describe and predict blood damage. In this work, simulations of experiments in a Couette flow viscometer and a capillary tube were used to examine extensive properties of the turbulent flow field and to investigate contributing factors for red blood cell hemoglobin release in turbulence by eddy analysis. It was found that hemolysis occurred when dissipative eddies were comparable in size to the red blood cells. The Kolmogorov length scale was used to quantify the size of smaller turbulent eddies, indicating correspondence of hemolysis with number and surface area of eddies smaller than about 10 μm when a k-ε turbulence model is adopted.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Ozturk M,O'Rear EA,Papavassiliou DV

doi

10.1111/aor.12572

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

E227-39

issue

12

eissn

0160-564X

issn

1525-1594

journal_volume

39

pub_type

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