Abstract:
:We aim to evaluate clinical outcomes of emergent extracorporeal membrane oxygenation (ECMO) implantation in newborns with life-threatening meconium aspiration syndrome (MAS) in peripheral hospitals with Hub and Spoke (HandS) setting. We retrospectively reviewed all neonates presenting with MAS, with no other comorbidities, treated with HandS ECMO, in peripheral hospitals. Team activation time (TAT) was described as the time from first alerting call to ECMO support initiation. From May 2014 to December 2016, 4 patients met our inclusion criteria. In addition, 2 cases occurred on the same day, requiring a second simultaneous HandS ECMO team activation. All patients were younger than 8 days of life (1, 1, 4, and 7), with a mean BSA 0.21 ± 0.03m2 , and TAT of 203, 265, 320, and 340 min. One patient presented ventricular fibrillation after priming administration. Veno-arterial ECMO was established in all patients after uneventful surgical neck vessels cannulation (right carotid artery and jugular vein). Mean time from skin incision to ECMO initiation was 19 ± 1.4 min. Mean length of ECMO support was 2.75 ± 1.3 days. All patients were weaned off support without complications. At a mean follow up of 20.5 ± 7.8 months, all patients are alive, with no medications, normal somatic growth, and neuropsychological development. MAS is a life-threatening condition that can be successfully managed with ECMO support. A highly trained multidisciplinary HandS ECMO team is crucial for the successful management of these severely ill newborns in peripheral hospitals.
journal_name
Artif Organsjournal_title
Artificial organsauthors
Fichera D,Zanella F,Fabozzo A,Doglioni N,Trevisanuto D,Lolli E,Vida V,Ceccherini E,Ebraico A,Stellin G,Padalino Mdoi
10.1111/aor.13270subject
Has Abstractpub_date
2019-01-01 00:00:00pages
76-80issue
1eissn
0160-564Xissn
1525-1594journal_volume
43pub_type
杂志文章abstract::The aim of this study is to evaluate the effect of temperature on cerebral oxygen metabolism at total body flow bypass and antegrade cerebral perfusion (ACP). Neonatal piglets were put on cardiopulmonary bypass (CPB) with the initial flow rate of 200mL/kg/min. After cooling to 18°C (n=6) or 25°C (n=7), flow was reduce...
journal_title:Artificial organs
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journal_title:Artificial organs
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journal_title:Artificial organs
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doi:10.1111/j.1525-1594.2006.00314.x
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journal_title:Artificial organs
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journal_title:Artificial organs
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journal_title:Artificial organs
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journal_title:Artificial organs
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journal_title:Artificial organs
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Artificial organs
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Artificial organs
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更新日期:2018-12-01 00:00:00
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