Flow through an outlet cannula of a rotary ventricular assist device.

abstract：:Extracorporeal membrane oxygenation (ECMO) is gaining importance in the perioperative management of lung transplant patients. To date, the ideal substance for anticoagulation of ECMO patients is still a matter of debate. In this study, we describe our experience with the use of low molecular weight heparin (LMWH) in c...

journal_title：Artificial organs

authors： Gratz J,Pausch A,Schaden E,Baierl A,Jaksch P,Erhart F,Hoetzenecker K,Wiegele M

更新日期：2020-06-01 00:00:00

abstract：:Roller pumps have been widely used in the ventricular assist field for many years, while the significant hemolysis caused by its mechanical stress is still a fundamental problem. Although the usual under-occlusion setting was considered as an effective method to reduce the hemolysis rate, its nonocclusive condition of...

journal_title：Artificial organs

authors： Zhou Y,Sun B,Chen M,Cui C

更新日期：2020-07-31 00:00:00

abstract：:Ventricular assist devices (VADs) are considered the standard of care for end-stage heart failure (HF) patients. Despite increasing confidence in the technology, evidence data, endorsement by scientific societies and guidelines, the number of implants reached a steady state and is not increasing at the expected pace. ...

journal_title：Artificial organs

authors： Barbone A,Pagliaro B,Basciu A,Iaccarino A,Droandi G,Romano G,Citterio E,Fumero A,Torracca L,Pini D

更新日期：2020-04-23 00:00:00

abstract：:This study was planned to investigate whether part of the energy produced by cardiac contraction to propel blood toward the systemic circulation can be used to increase the coronary flow in systole. Ten devices (I-X) designed to divert laterally part of a flow column (without substantially increasing resistance to flo...

journal_title：Artificial organs

authors： Moulopoulos S,Stamatelopoulos S,Boufas D,Yannopoulos C,Marousis G,Kouvaras G

更新日期：1979-11-01 00:00:00

abstract：:Pump power loss is defined as input power that is not used for the output work of the pump. Less pump power loss means a higher pump efficiency. A common opinion is that the pump power loss is closely related to heat generation of the pump, which may affect not only the endurance of pump materials, but also blood dama...

journal_title：Artificial organs

authors： Takami Y,Nakazawa T,Makinouchi K,Glueck J,Ohara Y,Benkowski RJ,Nosé Y

更新日期：1996-07-01 00:00:00

abstract：:Monoclonal antibodies for targeting cytotoxic conjugates to tumor cells are currently being evaluated together with extracorporeal affinity adsorption. The aim of the adsorption was to reduce undesired side effects in normal organs and to increase the tumor-to-normal tissue ratios. This technique is also applicable to...

journal_title：Artificial organs

authors： Mårtensson L,Nilsson R,Sjögren HO,Strand SE,Tennvall J

更新日期：2007-04-01 00:00:00

abstract：:This paper discussed issues of ethical assessment and moral concern associated with organ replacement and physical enhancement: research, allocation, organ donation, artificial organs, xenografts, biomaterials, and neuromaterials. While emphasizing the medical and moral benefits over associated risks, it calls for a b...

journal_title：Artificial organs

authors： Kielstein R,Sass HM

更新日期：1995-05-01 00:00:00

abstract：:Polyvinyl chloride (PVC) is one of the most frequently used polymers for the manufacturing of medical devices. Limitations for its usage are based upon unfavorable surface properties of the polymer including its hydrophobicity and lack of functionalities in order to increase its versatility. To address this issue, wet...

journal_title：Artificial organs

authors： Gabriel M,Strand D,Vahl CF

更新日期：2012-09-01 00:00:00

abstract：:Vecuronium is a curaric agent, largely used in anesthesia. Indications as to its employ in uremic patients appear to be debated because of partial renal elimination of the drug. A 52-year-old hemodialyzed woman required transplantectomy for rejection. At awakeness after general anesthesia (induced with fentanyl, propo...

journal_title：Artificial organs

authors： Rollino C,Visetti E,Borsa S,Pignataro A,Pozzato M,Vallero A,Quarello F

更新日期：2000-05-01 00:00:00

abstract：:This study compares the effects of polyethylene glycol (PEG) modified bovine hemoglobin on vascular half-life and renal function in rabbits to those of unmodified bovine hemoglobin. Renal function was assessed by the measurement of the glomerular filtration rate, urinalysis, blood chemistries, hemoglobin (Hb) excretio...

journal_title：Artificial organs

authors： Conover CD,Gilbert CW,Shum KL,Shorr RG

更新日期：1997-08-01 00:00:00

abstract：:The aim of the study is to measure the volume of homologous blood needed for one pediatric patient during his hospital stay. Over a 4-month period, all the patients operated upon with a blood prime or requiring blood transfusion during their hospital stay were included in this study.The cardiopulmonary bypass protocol...

journal_title：Artificial organs

authors： Durandy Y

更新日期：2010-11-01 00:00:00

abstract：:Our aim was to study the feasibility of implanting the Infant Jarvik 2015 in patients weighing less than 8 kg. The Infant Jarvik 2015 left ventricular assist device (LVAD) was tested in a hybrid simulator of the cardiovascular system reproducing specific patients' hemodynamics for different patient weights (2-7 kg). F...

journal_title：Artificial organs

authors： Di Molfetta A,Zielinski K,Ferrari G,Kozarski M,Okrzeja P,Iacobelli R,Filippelli S,Perri G,Darowski M,Massetti M,Jarvik R,Amodeo A

更新日期：2019-01-01 00:00:00

abstract：:Recently, the use of electrolyzed solutions has attracted considerable interest in Japan. This study investigates the efficiency of electrolyzed solutions as disinfecting agents (DA) in the reuse of dialyzers and compares their efficiency to that of other disinfectants currently in use. The following 3 methods were em...

journal_title：Artificial organs

authors： Tanaka N,Tanaka N,Fujisawa T,Daimon T,Fujiwara K,Yamamoto M,Abe T

更新日期：2000-12-01 00:00:00

abstract：:A new intravascular pumping oxygenator (IVPO) was developed for intravascular gas exchange and circulatory assistance in critically ill patients with respiratory and circulatory failure. The IVPO utilizes new silicone hollow fibers (diameter, 1 mm; membrane width, 50 microns) and consists of two driving tubes for the ...

journal_title：Artificial organs

authors： Sueda T,Fukunaga S,Morita S,Sueshiro M,Hirai S,Okada K,Orihashi K,Matsuura Y

更新日期：1997-01-01 00:00:00

abstract：:In this study a highly biocompatible polymer membrane was prepared by surface modification. An artificial cornea was also developed for clinical applications. Silicone rubber (SR) membrane was grafted with hydrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA) and acrylic acid by plasma induced grafted polyme...

journal_title：Artificial organs

authors： Hsiue GH,Lee SD,Chang PC

更新日期：1996-11-01 00:00:00

abstract：:A comparative study of the thrombogenicity of several microporous membranes was performed using an ex vivo system simulating the conditions in an artificial lung. A study of platelet adhesion and adsorbed protein layer indicated that the membranes separated into three groups. Copolyurethane membranes adsorbed very few...

journal_title：Artificial organs

authors： Knight PM,Lyman DJ

更新日期：1985-02-01 00:00:00

abstract：:What the most causative factor affecting hemolysis is still controversial. To resolve this problem, we investigated the relationship between hemolysis and heat generation in six types of centrifugal blood pumps (Bio-Pump, Delphin, Capiox, Nikkiso, Isoflow, and Toyobo). The analyzed parameters were index of hemolysis i...

journal_title：Artificial organs

authors： Araki K,Taenaka Y,Masuzawa T,Tatsumi E,Wakisaka Y,Watari M,Nakatani T,Akagi H,Baba Y,Anai H

更新日期：1995-09-01 00:00:00

abstract：:Plasma levels of the platelet markers beta-thromboglobulin (beta-TG) and platelet factor 4 (PF4) are among the most sophisticated indexes of biocompatibility available to evaluate new members for hemodialysis. This investigation was designed to determine the extent of platelet activation by measuring the alpha-granule...

journal_title：Artificial organs

authors： Buccianti G,Giaretto S,Pogliani EM,Lorenz M,Valenti G,Bianchi ML,Cresseri D

更新日期：1987-10-01 00:00:00

abstract：:For many years, it was thought that nonpulsatile perfusion produced physiological and circulatory abnormalities. Since 1977, Yukihiko Nosé and his colleagues have challenged this misconception. Toward that end, they did show that if a 20% higher blood flow uses more than that required for a pulsatile blood pump, then ...

journal_title：Artificial organs

authors： Nosé Y,Kawahito K,Nakazawa T

更新日期：1996-05-01 00:00:00

abstract：:Many types of rotary blood pumps and pump control methods have recently been developed with the goal of clinical use. From experiments, we know that pump flow spontaneously increases during exercise without changing pump control parameters. The purpose of this study was to determine the hemodynamics associated with th...

journal_title：Artificial organs

authors： Akimoto T,Yamazaki K,Litwak P,Litwak KN,Tagusari O,Mori T,Antaki JF,Kameneva MV,Watach MJ,Umezu M,Tomioka J,Kormos RL,Koyanagi H,Griffith BP

更新日期：1999-08-01 00:00:00

abstract：:Malnutrition is a common feature seen in chronic dialysis patients, and the survival rate of obese patients receiving such treatment is higher than that of lean patients. Irrespective of obesity or diabetes, dialysis patients commonly have insulin resistance, and the leading cause of death is cardiovascular (CV) disea...

journal_title：Artificial organs

authors： Tanaka S,Yano S,Sheikh AM,Nagai A,Sugimoto T

更新日期：2014-07-01 00:00:00

abstract：:Cardiomyoplasty has been proposed as an alternative surgical treatment for congestive heart failure. The girdling effect of the muscle wrap is believed to reduce diastolic wall stress. We tested the hypothesis that nonstimulated or passive cardiomyoplasty (CDM) would reduce hemodynamic deficits in rats with experiment...

journal_title：Artificial organs

authors： De Angelis K,Leirner AA,Irigoyen MC,Cestari IA

更新日期：2001-11-01 00:00:00

abstract：:The weight gain of IVOX devices removed from the first 49 human clinical trials patients after from 1 to 29 days of implantation into the venae caval blood stream has been assessed. Each patient had received sufficient systemic heparin to maintain activated clotting times between 150 and 200 s while the IVOX device wa...

journal_title：Artificial organs

authors： Imai H,Schaap RN,Mortensen JD

更新日期：1994-11-01 00:00:00

abstract：:Different from the existing tissue engineering strategies, rapid prototyping (RP) techniques aim to automatically produce complex organs directly from computer-aided design freeform models with high resolution and sophistication. Analogous to building a nuclear power plant, cell biology (especially, renewable stem cel...

journal_title：Artificial organs

authors： Wang X

更新日期：2012-11-01 00:00:00

abstract：:Cybernetics-based concepts can allow for complete independence for paralyzed individuals, including sensory motor recovery. Spinal cord injuries are responsible for a huge stress on health and a financial burden to society. This article focuses on novel procedures such as functional diagnosis for paraplegics and tetra...

journal_title：Artificial organs

authors： Varoto R,Cliquet A Jr

更新日期：2015-10-01 00:00:00

abstract：:Patients receiving mechanical circulatory support often present with heightened inflammation and free radical production associated with pre-existing conditions in addition to that which is due to blood interactions with nonbiological surfaces. The aim of this experimental laboratory study was to assess the deformabil...

journal_title：Artificial organs

authors： McNamee AP,Horobin JT,Tansley GD,Simmonds MJ

更新日期：2018-02-01 00:00:00

abstract：:Fibroblast cell culture was performed to evaluate cell adhesion and cell morphology on novel hydrolyzable copolymers composed of poly(D,L-lactic acid) (PDLA) macromonomer, 2-methacryloyloxyethyl phosphorylcholine (MPC), and n-butyl methacrylate. The copolymers were used as cell culture materials for regulating the int...

journal_title：Artificial organs

authors： Watanabe J,Ishihara K

更新日期：2003-03-01 00:00:00

abstract：:Changes in plasma sodium (Na) concentration during hemodialysis were predicted by changes in Na concentration of the dialysate at equilibrium with the plasma, according to the formula C't = CD - (CD - C'0) [(V0 - QFt)/V0]A/QF, where C'0 and C't are the Na concentration of the dialysate at equilibrium with the plasma a...

journal_title：Artificial organs

authors： Man NK,Petitclerc T,Tien NQ,Jehenne G,Funck-Brentano JL

更新日期：1985-05-01 00:00:00

abstract：:The aim of this study was to verify if dialysis solution volumes used in patients on continuous ambulatory peritoneal dialysis (CAPD) interfere with pulmonary function and if the pulmonary volumes interfere with the lymphatic absorption of the peritoneal cavity. We submitted 10 CAPD patients with a mean age of 48 +/- ...

journal_title：Artificial organs

authors： Marmanillo CG,Pecoits-Filho RF,Romão JE Jr,Kakehashi ET,Sabbaga E,Marcondes M,Abensur H

更新日期：2001-11-01 00:00:00

abstract：:Multiple observational studies along with a limited number of randomized clinical trials suggest that intensive hemodialysis (IHD) not only improves outcomes for uremic patients undergoing chronic dialysis but does so with a more favorable cost/benefit ratio compared with conventional hemodialysis. As a result of this...

journal_title：Artificial organs

authors： Naso A,Scaparrotta G,Naso E,Calò LA

更新日期：2015-09-01 00:00:00