Hemolysis and heat generation in six different types of centrifugal blood pumps.

Abstract:

:What the most causative factor affecting hemolysis is still controversial. To resolve this problem, we investigated the relationship between hemolysis and heat generation in six types of centrifugal blood pumps (Bio-Pump, Delphin, Capiox, Nikkiso, Isoflow, and Toyobo). The analyzed parameters were index of hemolysis in fresh goat blood, pumping performance, and heat generation in a thermally isolated mock circuit. These parameters were analyzed at a flow rate of 5 L/min by changing the pressure head (100 mm Hg and 500 mm Hg). At 500 mm Hg of pressure head, the Bio-Pump needed the highest rotation number and showed the highest hemolytic rate and heat generation. The index of hemolysis is well correlated to heat generation (r2 = 0.721). Heat may originate from the motor by conduction, hydraulic energy loss, and mechanical friction between the shaft and seal. We strongly suspect that hemolysis was caused by a factor such as mechanical friction which generates heat locally.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Araki K,Taenaka Y,Masuzawa T,Tatsumi E,Wakisaka Y,Watari M,Nakatani T,Akagi H,Baba Y,Anai H

doi

10.1111/j.1525-1594.1995.tb02453.x

subject

Has Abstract,Author List Incomplete

pub_date

1995-09-01 00:00:00

pages

928-32

issue

9

eissn

0160-564X

issn

1525-1594

journal_volume

19

pub_type

杂志文章
  • The Effect of Diode Laser With Different Parameters on Root Fracture During Irrigation Procedure.

    abstract::The aim of this study is to compare the effect of a single diode laser application and agitation of EDTA with diode laser with different parameters at different time intervals on root fracture. Ninety mandibular incisors were instrumented except the negative control group. The specimens were divided randomly into 10 g...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12608

    authors: Karataş E,Arslan H,Topçuoğlu HS,Yılmaz CB,Yeter KY,Ayrancı LB

    更新日期:2016-06-01 00:00:00

  • Microencapsulation of crystalline insulin or islets of Langerhans: an insulin diffusion study.

    abstract::Microcapsules containing insulin crystals or islets of Langerhans were made by extruding a mixture of insulin crystals or islets and sodium alginate into a calcium chloride solution, and then coating it with poly-l-lysine. When these microcapsules were incubated at 37 degrees C, insulin could be detected readily in th...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1983.tb04187.x

    authors: Leung YF,O'Shea GM,Goosen MF,Sun AM

    更新日期:1983-05-01 00:00:00

  • The SlideReactor--a simple hollow fiber based bioreactor suitable for light microscopy.

    abstract::Most bioartificial liver support systems are based on hollow fiber capillaries within modified dialysis cartridges or more sophisticated bioreactor constructions. Due to their design microscopic follow-up of reorganization and growth of tissue between the hollow fibers is not possible. The SlideReactor is a simple hol...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2005.29049.x

    authors: Sauer IM,Schwartlander R,Schmid J,Efimova E,Vondran FW,Kehr D,Pless G,Spinelli A,Brandenburg B,Hildt E,Neuhaus P

    更新日期:2005-03-01 00:00:00

  • A nonsurgical technique for blood access in extracorporeal affinity adsorption of antibodies in rats.

    abstract::Monoclonal antibodies for targeting cytotoxic conjugates to tumor cells are currently being evaluated together with extracorporeal affinity adsorption. The aim of the adsorption was to reduce undesired side effects in normal organs and to increase the tumor-to-normal tissue ratios. This technique is also applicable to...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2007.00380.x

    authors: Mårtensson L,Nilsson R,Sjögren HO,Strand SE,Tennvall J

    更新日期:2007-04-01 00:00:00

  • Circulatory support for patients experiencing postcardiotomy cardiogenic shock: analysis of risk factors for death and long-term follow-up.

    abstract::Over the last 5 years, 12 patients received ventricular assist devices (VADs) while in postcardiotomy cardiogenic shock. There were 7 male and 5 female patients ranging in age from 22 to 73 years (average age, 54). Eight patients underwent surgery for valve replacements, 3 for coronary artery bypass graftings, and 1 f...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1993.tb00608.x

    authors: Murakami T,Nakayama H,Irie H,Kino K,Hisamochi K,Koomoto T,Takagaki M,Sugawara E,Senoo Y,Teramoto S

    更新日期:1993-07-01 00:00:00

  • Substitution of acetic acid for hydrochloric acid in the bicarbonate buffered dialysate.

    abstract::In a multicenter study including 5 dialysis units, blood acetate changes during 4 h dialysis sessions in 141 patients treated with a 4 mM acetate-containing bicarbonate dialysate (ABD) were evaluated and compared to the values of 114 patients using an acetate-free bicarbonate dialysate (AFD). Acetate-free bicarbonate ...

    journal_title:Artificial organs

    pub_type: 杂志文章,多中心研究

    doi:10.1046/j.1525-1594.1998.06205.x

    authors: Fournier G,Potier J,Thébaud HE,Majdalani G,Ton-That H,Man NK

    更新日期:1998-07-01 00:00:00

  • Measurement of the closing behavior of the björk-shiley monoleaflet mechanical heart valve with an electrohydraulic total artificial heart.

    abstract::When cavitation occurs near a material surface of a mechanical heart valve (MHV), pits on the surface of the MHV and hemolysis are caused. Therefore, it is very important to investigate the possibility of the occurrence of cavitation in an MHV. To study the possibility of cavitation occurrence in a 25 mm Björk-Shiley ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2003.06981.x

    authors: Lee H,Tsukiya T,Homma A,Taenaka Y,Tatsumi E,Takano H

    更新日期:2003-08-01 00:00:00

  • Modified DALI LDL-apheresis using trisodium citrate anticoagulation plus bicarbonate or lactate-buffered hemofiltration substitution fluids as primers.

    abstract:BACKGROUND:DALI (direct adsorption of lipids) is the first LDL-apheresis technique able to adsorb low-density lipoprotein (LDL) and lipoproteina) directly from whole blood. In the standard procedure, acid citrate dextrose (ACD-A) is used as anticoagulation and the adsorber is rinsed with a specially manufactured primin...

    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章

    doi:10.1046/j.1525-1594.2003.07104.x

    authors: Bosch T,Wendler T,Maschke H

    更新日期:2003-06-01 00:00:00

  • Physical testing of elastomers for cardiovascular applications.

    abstract::There are presently no short-term in vitro fatigue tests available that can predict long-term in vivo performance of elastomers in physiological environments. Thus, the introduction of new and better elastomers for cardiovascular applications is hampered in the development stage by lack of data about which materials s...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1983.tb04162.x

    authors: McMillin CR

    更新日期:1983-02-01 00:00:00

  • Magnetic suspension of the rotor of a ventricular assist device of mixed flow type.

    abstract::This work presents results of preliminary studies concerning application of magnetic bearing in a ventricular assist device (VAD) being developed by Dante Pazzanese Institute of Cardiology-IDPC (São Paulo, Brazil). The VAD-IDPC has a novel architecture that distinguishes from other known VADs. In this, the rotor has a...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2008.00551.x

    authors: Horikawa O,de Andrade AJ,da Silva I,Bock EG

    更新日期:2008-04-01 00:00:00

  • Miniaturized centrifugal ventricular assist device for bridge to decision: Preclinical chronic study in a bovine model.

    abstract::We developed a novel miniaturized extracorporeal centrifugal pump "BIOFLOAT NCVC (Nipro Corporation Osaka, Japan) as a ventricular assist device (VAD) and performed a preclinical study that is part of the process for its approval as a bridge to decision by the pharmaceutical and medical device agencies. The aim of thi...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13459

    authors: Shimamura J,Mizuno T,Takewa Y,Tsukiya T,Naito N,Akiyama D,Iizuka K,Katagiri N,Nishimura T,Ono M,Tatsumi E

    更新日期:2019-09-01 00:00:00

  • Hemodynamic evaluation of a new left ventricular assist device: an integrated cardioassist catheter as a pulsatile left ventricle-femoral artery bypass.

    abstract::We developed a new left ventricular (LV) assist catheter (transaortic valve from LV to femoral artery) that is implemented percutaneously and exerted as a synchronous pulsatile partial LV flow support with conventional intraaortic balloon pump (IABP) driving system and centrifugal pump system. We investigated whether ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1992.tb00311.x

    authors: Ide H,Yamaguchi A,Ino T,Matsumoto H,Fujimasa I

    更新日期:1992-06-01 00:00:00

  • Clinical experience with BioMedicus centrifugal ventricular support in 172 patients.

    abstract::One hundred and seventy-two patients at The Methodist Hospital in Houston, Texas, were placed on BioMedicus centrifugal ventricular support. One hundred thirty-nine patients were male and 33 were female with a mean age of 59.7 years. Reasons for support were postcardiotomy cardiac failure (129 patients), cardiac allog...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1995.tb02419.x

    authors: Noon GP,Ball JW Jr,Papaconstantinou HT

    更新日期:1995-07-01 00:00:00

  • Standing up with denervated muscles in humans using functional electrical stimulation.

    abstract::The use of electrical stimulation for denervated muscles is still considered to be a controversial issue by many rehabilitation facilities and medical professionals because prior clinical experience has shown that treating denervated muscle tissue using exponential current over a long time period constitutes an imposs...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1999.06376.x

    authors: Kern H,Hofer C,Strohhofer M,Mayr W,Richter W,Stöhr H

    更新日期:1999-05-01 00:00:00

  • Paracorporeal artificial heart in postoperative heart failure.

    abstract::A pneumatically driven artificial heart with a tubular silicone rubber membrane and disc valves was used for functional heart replacement in the paracorporeal mode. A fluidic drive system allows adjustment of the heart rate, positive and negative pressures and systole/diastole ratio. Since August, 1977, the artificial...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1978.tb03465.x

    authors: Turina MT,Bosio R,Senning A

    更新日期:1978-08-01 00:00:00

  • Reversal of experimental posthepatectomy liver failure in pigs: a new application of hepatocyte bioreactors.

    abstract::Postoperative liver failure remains a major cause of morbidity and mortality after extensive hepatectomies. This study aims to evaluate the effectiveness of a hepatocyte bioreactor in the treatment of experimental post-hepatectomy liver failure. Our experimental model included a combination of a side-to-side portacava...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2010.01016.x

    authors: Arkadopoulos N,Kostopanagiotou G,Nastos C,Papalois A,Papoutsidakis N,Kalimeris K,Defterevos G,Kanna T,Polyzois K,Kampouroglou G,Kypriotis D,Costopanagiotou C,Pafiti A,Tzanatos H,Smyrniotis V

    更新日期:2011-01-01 00:00:00

  • Investigation of the inherent left-right flow balancing of rotary total artificial hearts by means of a resistance box.

    abstract::With the incidence of end-stage heart failure steadily increasing, the need for a practical total artificial heart (TAH) has never been greater. Continuous flow TAHs (CFTAH) are being developed using rotary blood pumps (RBPs), leveraging their small size, mechanical simplicity, and excellent durability. To completely ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13631

    authors: Nestler F,Timms DL,Stevens M,Bradley AP,Wilson SJ,Kleinheyer M,Lovell N,Frazier OH,Cohn WE

    更新日期:2020-06-01 00:00:00

  • The impact of obesity on outcomes in patients receiving extracorporeal life support.

    abstract::Extracorporeal life support (ECLS) has been increasingly utilized to manage cardiac and pulmonary dysfunction. The impact of obesity on outcomes of ECLS is poorly defined. The purpose of the study was to compare in-hospital mortality, resource use, complications, and readmissions in obese versus non-obese patients rec...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13752

    authors: Christian-Miller N,Hadaya J,Nakhla M,Sanaiha Y,Madrigal J,Emami S,Cale M,Sareh S,Benharash P

    更新日期:2020-11-01 00:00:00

  • Computational fluid dynamics prediction of blood damage in a centrifugal pump.

    abstract::This study explores a quantitative evaluation of blood damage that occurs in a continuous flow left ventricular assist device due to fluid stress. Computational fluid dynamics (CFD) analysis is used to track the shear stress history of 388 particle streaklines. The accumulation of shear and exposure time is integrated...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2003.00026.x

    authors: Song X,Throckmorton AL,Wood HG,Antaki JF,Olsen DB

    更新日期:2003-10-01 00:00:00

  • Fluid-Structure Interactions Analysis of Shear-Induced Modulation of a Mesenchymal Stem Cell: An Image-Based Study.

    abstract::Although effects of biochemical modulation of stem cells have been widely investigated, only recent advances have been made in the identification of mechanical conditioning on cell signaling pathways. Experimental investigations quantifying the micromechanical environment of mesenchymal stem cells (MSCs) are challengi...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12547

    authors: Ghaemi RV,Vahidi B,Sabour MH,Haghighipour N,Alihemmati Z

    更新日期:2016-03-01 00:00:00

  • Acellular Endocardium as a Novel Biomaterial for the Intima of Tissue-Engineered Small-Caliber Vascular Grafts.

    abstract::We aimed to investigate whether acellular endocardium can be used as a useful biomaterial for the intima of engineered small-caliber vascular grafts. Fresh endocardium was harvested from the swine left atrium and was decellularized by digestion with the decellularization solution of Triton X-100 and SDS containing DNa...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12814

    authors: Wang F,Guan X,Wu T,Qiao J,Han Z,Wu J,Yu X,You Q

    更新日期:2016-12-01 00:00:00

  • (13) C Breath Tests Are Feasible in Patients With Extracorporeal Membrane Oxygenation Devices.

    abstract::Temporary extracorporeal membrane oxygenation (ECMO) has been established as an essential part of therapy in patients with pulmonary or cardiac failure. As physiological gaseous exchange is artificially altered in this patient group, it is debatable whether a (13) C-breath test can be carried out. In this proof of tec...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12634

    authors: Bednarsch J,Menk M,Malinowski M,Weber-Carstens S,Pratschke J,Stockmann M

    更新日期:2016-07-01 00:00:00

  • Evaluation of platelet adhesion and activation on materials for an implantable centrifugal blood pump.

    abstract::A totally implantable centrifugal artificial heart has been developed in which a pivot bearing supported centrifugal pump is used as a blood pump. The following have been adopted as blood contacting materials in our pump: titanium alloy (Ti-6A1-4V) for the housing and impeller, alumina ceramic (Al2O3) for the male piv...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1998.6184r.x

    authors: Takami Y,Yamane S,Makinouchi K,Niimi Y,Sueoka A,Nosé Y

    更新日期:1998-09-01 00:00:00

  • Detection of suction and regurgitation of the implantable centrifugal pump based on the motor current waveform analysis and its application to optimization of pump flow.

    abstract::In this study, a detection algorithm for suction and regurgitation of the centrifugal pump during left heart bypass without relying on external flow or pressure sensors was developed and evaluated in acute studies using adult goats. The detection scheme relies on power spectral density (PSD) analysis of the motor curr...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1999.06397.x

    authors: Yuhki A,Hatoh E,Nogawa M,Miura M,Shimazaki Y,Takatani S

    更新日期:1999-06-01 00:00:00

  • Use of clinical guidelines for treatment of anemia among hemodialysis patients.

    abstract::Changing financial incentives have strongly influenced dosing patterns of recombinant human erythropoietin (rHuEPO) since its introduction in 1989. Although guidelines for prescribing rHuEPO exist, the extent to which they are adhered to is unknown. Using a retrospective cohort observational study design, the factors ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2000.06495.x

    authors: Thamer M,Richard CM,Klinkmann J,Ivanovich P,Lang G,Cotter DJ

    更新日期:2000-02-01 00:00:00

  • Peritoneal dialysis solutions for the 21st century.

    abstract::Existing peritoneal dialysis (PD) solutions were formulated for the maintenance of fluid and electrolyte balance, correction of metabolic acidosis, and the removal of metabolic waste products. Solutions currently in development are designed to improve biocompatibility by neutralizing pH and reducing glucose degradatio...

    journal_title:Artificial organs

    pub_type: 杂志文章,评审

    doi:10.1046/j.1525-1594.1998.06022.x

    authors: Martis L,Chen C,Moberly JB

    更新日期:1998-01-01 00:00:00

  • Use of tactile stiffness to detect fatigue in the latissimus dorsi muscle.

    abstract::In clinical settings, no method has been established to examine the fatigue of a latissimus dorsi muscle (LDM) preconditioned for cardiomyoplasty. We examined the feasibility of measuring muscle stiffness (tactile stiffness) to evaluate muscle fatigue in situ using our tactile sensor. We stimulated canine LDM with bur...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2000.06551.x

    authors: Inaba H,Miyaji K,Kaneko Y,Ohtsuka T,Ezure M,Tambara K,Takamoto S,Omata S

    更新日期:2000-10-01 00:00:00

  • Device exchange versus nonexchange modalities in left ventricular assist device-specific infections: A systematic review and meta-analysis.

    abstract::No standardized treatment algorithm exists for the management of continuous-flow left ventricular assist device (CF-LVAD)-specific infections. The aim of this systematic review and meta-analysis was to compare the outcomes of CF-LVAD-specific infections as managed by device exchange to other treatment modalities not i...

    journal_title:Artificial organs

    pub_type: 杂志文章,meta分析

    doi:10.1111/aor.13378

    authors: Bauer TM,Choi JH,Luc JGY,Weber MP,Moncho Escrivá E,Patel S,Maynes EJ,Boyle AJ,Samuels LE,Entwistle JW,Morris RJ,Massey HT,Tchantchaleishvili V

    更新日期:2019-05-01 00:00:00

  • Engineering of vascular grafts with genetically modified bone marrow mesenchymal stem cells on poly (propylene carbonate) graft.

    abstract::Bone marrow mesenchymal stem cells (MSCs) have demonstrated their pluripotency to differentiate into different cell lineages and may be an alternative cell source for vascular tissue engineering. The objective of this study is to create small diameter vessels by seeding and culture of genetically modified MSCs onto a ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2006.00322.x

    authors: Zhang J,Qi H,Wang H,Hu P,Ou L,Guo S,Li J,Che Y,Yu Y,Kong D

    更新日期:2006-12-01 00:00:00

  • Is the New Infant Jarvik 2015 Suitable for Patients

    abstract::Our aim was to study the feasibility of implanting the Infant Jarvik 2015 in patients weighing less than 8 kg. The Infant Jarvik 2015 left ventricular assist device (LVAD) was tested in a hybrid simulator of the cardiovascular system reproducing specific patients' hemodynamics for different patient weights (2-7 kg). F...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13302

    authors: Di Molfetta A,Zielinski K,Ferrari G,Kozarski M,Okrzeja P,Iacobelli R,Filippelli S,Perri G,Darowski M,Massetti M,Jarvik R,Amodeo A

    更新日期:2019-01-01 00:00:00