Evaluation of platelet adhesion and activation on materials for an implantable centrifugal blood pump.

abstract：:Postoperative liver failure remains a major cause of morbidity and mortality after extensive hepatectomies. This study aims to evaluate the effectiveness of a hepatocyte bioreactor in the treatment of experimental post-hepatectomy liver failure. Our experimental model included a combination of a side-to-side portacava...

journal_title：Artificial organs

authors： Arkadopoulos N,Kostopanagiotou G,Nastos C,Papalois A,Papoutsidakis N,Kalimeris K,Defterevos G,Kanna T,Polyzois K,Kampouroglou G,Kypriotis D,Costopanagiotou C,Pafiti A,Tzanatos H,Smyrniotis V

更新日期：2011-01-01 00:00:00

abstract：:Jaundice is characterized by an excessive accumulation of bilirubin in the blood and tissues. A novel approach to reduce plasma levels of bilirubin by blocking its enterohepatic circulation was investigated. The treatment consisted of oral administration of immobilized bilirubin oxidase, which could oxidize bilirubin ...

journal_title：Artificial organs

authors： Soltys PJ,Mullon C,Langer R

更新日期：1992-08-01 00:00:00

abstract：:This work describes the preparation and characterization of anionic collagen composites with rhamsan and vinylidene fluoride-trifluorethylene with improved rheological and dielectric properties without loss of collagen secondary structure with an interaction occurring between both macromolecules of the composites. On ...

journal_title：Artificial organs

authors： Goissis G,Piccirili L,Goes JC,de Guzzi Plepis AM,Das-Gupta DK

更新日期：1998-03-01 00:00:00

abstract：:The injurious effects of reactive oxygen species on venous tissues and the potential protective role played by green tea polyphenol (GTPP) on human saphenous veins were investigated. Oxidative stress was induced exogenously in the vein segments, either by adding 0.8 or 1.6 M of H2O2, or by using 80 or 160 U/L of xanth...

journal_title：Artificial organs

authors： Han DW,Suh H,Park YH,Cho BK,Hyon SH,Park JC

更新日期：2003-12-01 00:00:00

abstract：:The growing practice of dialyzer reuse in recent years is mainly based on medical and economic considerations. However, adverse reactions such as immunohemolytic anemia due to anti-Nform antibody associated with dialyzer reuse have been reported. In this study, scanning electron microscopy and cytologic staining were ...

journal_title：Artificial organs

authors： Ng YY,Yang AH,Wong KC,Lan HY,Hung TL,Kerr PG,Huang TP

更新日期：1996-01-01 00:00:00

abstract：:To provide percutaneous access, a new circulatory assist system was developed. We call this newly developed system the modified assist device (MAD). The system is composed of a sac-type blood pump and cannula. Inflow and outflow valves are mounted in the apex and at the side wall 10 cm from the apex of the cannula, re...

journal_title：Artificial organs

authors： Imanishi K,Imachi K,Yoshito H,Isoyama T,Abe Y,Chinzei T,Mabuchi K,Kanda K,Tsutsui N,Suma K,Fujimasa I

更新日期：1996-02-01 00:00:00

abstract：:Centrifugal pumps are generally employed as nonpulsatile blood flow pumps; however, these pumps can produce pulsatile flow by periodically alternating the impeller rotation speed. This study investigates blood trauma due to the effect of pulse frequency and various ranges of pump speed. The hemolysis tests were conduc...

journal_title：Artificial organs

authors： Tayama E,Niimi Y,Takami Y,Ohashi Y,Ohtsuka G,Glueck JA,Mueller J,Nosé Y

更新日期：1997-12-01 00:00:00

abstract：:The effects of pyridoxalated hemoglobin polyoxyethylene conjugate (PHP) and other hemoglobin-related substances on arterial blood pressure (ABP) and heart rate (HR) were examined. Infusion of PHP and other hemoglobin-related substances elevated ABP and increased HR. The degree of the increase in ABP and HR did not dif...

journal_title：Artificial organs

authors： Kida Y,Maeda M,Iwata S,Iwashita Y,Goto K,Nishi K

更新日期：1995-02-01 00:00:00

abstract：:Upon introducing off-pump coronary artery bypass grafting (CABG), the indications for CABG were expanded to include patients who previously had no operative indications. For accurate anastomosis, various devices and methods have been developed. Bradycardia is easily induced by drug administration. However, this method...

journal_title：Artificial organs

authors： Kuniyoshi Y,Koja K,Miyagi K,Shimoji M,Uezu T,Arakaki K,Yamashiro S,Mabuni K,Senaha S

更新日期：2002-10-01 00:00:00

abstract：:The objective of this study is to compare the myocardium protective effect of Bretschneider's histidine-tryptophan-ketoglutarate (HTK) solution versus Modified St. Thomas' (STH) solution in pediatric cardiac surgery of Tetralogy of Fallot (TOF). Seventy-seven pediatric patients of TOF who received the total surgical r...

journal_title：Artificial organs

authors： Wang ZH,An Y,Du MC,Qin TJ,Liu YB,Xu HZ,Yang LQ

更新日期：2017-05-01 00:00:00

abstract：:Transcatheter aortic valve implantation (TAVI) has gained considerable acceptance in the past decade due to its lower risks than conventional open-heart surgery. However, the deformation and delamination of the leaflets during the crimping procedure have raised questions about the durability and long-term serviceabili...

journal_title：Artificial organs

authors： Mao J,Rassoli A,Tong Y,Rouse EN,Le-Bel G,How D,Germain L,Fatouraee N,Zhang Z,Reed RR,Guidoin R

更新日期：2019-10-01 00:00:00

abstract：:In a calf model, 3 standard and 3 heparin coated intraaortic balloons (IAB) were inserted and left deflated in the descending aorta during 20 min to simulate balloon rupture. At the end of the experiment, the IAB were examined, and 3 samples of each were collected for scanning electron microscopy (SEM) analysis. None ...

journal_title：Artificial organs

authors： Mueller XM,Tevaearai HT,Hayoz D,von Segesser LK

更新日期：1999-02-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are regarded as a potential autologous source for cartilage repair, because they can differentiate into chondrocytes by transforming growth factor-beta (TGF-beta) treatment under the 3-dimensional (3-D) culture condition. However, more efficient and versatile methods for chondrogenic diff...

journal_title：Artificial organs

authors： Lee HJ,Choi BH,Min BH,Son YS,Park SR

更新日期：2006-09-01 00:00:00

abstract：:Spiral/helical forms of blood flow have been observed in large arteries of the cardiovascular system, but their benefits remain underappreciated. Spiral flow has been postulated to improve near-wall washout, promoting anti-atherothrombotic conditions. This research aims to study the washout characteristics of spiral f...

journal_title：Artificial organs

authors： Huang Zhang P,Tkatch C,Newman R,Grimme W,Vainchtein D,Kresh JY

更新日期：2019-12-01 00:00:00

abstract：:A comparative study of the thrombogenicity of several microporous membranes was performed using an ex vivo system simulating the conditions in an artificial lung. A study of platelet adhesion and adsorbed protein layer indicated that the membranes separated into three groups. Copolyurethane membranes adsorbed very few...

journal_title：Artificial organs

authors： Knight PM,Lyman DJ

更新日期：1985-02-01 00:00:00

abstract：:The outgrowth of endothelial cells in an expanded polytetrafluoroethylene graft implanted in the canine inferior vena cava was studied by scanning electron microscopy. The adjacent endothelial cells of the vena cava started to invade the anastomotic area three days after the implantation and reached approximately the ...

journal_title：Artificial organs

authors： Ishimaru S,Berglin E,Hansson HA,Teger-Nilsson AC,William-Olsson G

更新日期：1981-11-01 00:00:00

abstract：:A belt worn controller and lithium-ion battery pack have been developed for use with the initial clinical trials of the Jarvik 2000 heart. Patient interface considerations, safety, and simplicity were major design inputs for the system. The controller was developed using all analog technology to avoid difficulties wit...

journal_title：Artificial organs

authors： Jarvik R,Scott V,Morrow M,Takecuhi E

更新日期：1999-06-01 00:00:00

abstract：:Coil-type silicone membrane oxygenators can only be used with roller blood pumps due to the resistance from the high blood flow. Therefore, during extracorporeal membrane oxygenation (ECMO) treatment, the combination of a roller pump and an oxygenator with a high blood flow resistance will induce severe hemolysis, whi...

journal_title：Artificial organs

authors： Motomura T,Maeda T,Kawahito S,Matsui T,Ichikawa S,Ishitoya H,Kawamura M,Nishimura I,Shinohara T,Oestmann D,Glueck J,Kawaguchi Y,Sato K,Nosé Y

更新日期：2002-11-01 00:00:00

abstract：:Medial opening-wedge has gained popularity in comparison to other techniques of high tibial osteotomy. This technique involves the creation of a gap in the tibia. Filling the gap with autologous iliac bone graft was recommended in the classic description, to prevent complications such as correction loss or delayed bon...

journal_title：Artificial organs

authors： Zorzi AR,da Silva HG,Muszkat C,Marques LC,Cliquet A Jr,de Miranda JB

更新日期：2011-03-01 00:00:00

abstract：:The objective of this clinical study is to determine whether correlation exists among cerebral and renal near-infrared spectroscopy (NIRS) measurements, renal Doppler ultrasonography parameters (resistive index, peak systolic velocity), and early postoperative clinical outcomes following cardiac surgery in neonates an...

journal_title：Artificial organs

authors： Örmeci T,Alkan-Bozkaya T,Özyüksel A,Ersoy C,Ündar A,Akçevin A,Türkoğlu H

更新日期：2015-01-01 00:00:00

abstract：:Our study investigated the reliability of appearance of rapid atrial swirl flow (RASF) by ultrasonography (US) in the right atrium (RA), which occurred as a result of rapid isotonic saline infusion (RISI) into the central venous catheter (CVC), in predicting catheter tip position. This prospective observational study ...

journal_title：Artificial organs

authors： Yesilbas O,Sevketoglu E,Kihtir HS,Talip Petmezci M,Akcay N,Kocoglu Barlas U,Palabiyik F

更新日期：2018-12-01 00:00:00

abstract：:The limited success of cardiac stem cell therapy has lately generated discussion regarding its effectiveness. We hypothesized that immediate cell loss after intramyocardial injection significantly obscures the regenerative potential of stem cell therapy. Therefore, our aim was to assess the distribution and quantity o...

journal_title：Artificial organs

authors： Martens A,Rojas SV,Baraki H,Rathert C,Schecker N,Zweigerdt R,Schwanke K,Rojas-Hernandez S,Martin U,Saito S,Schmitto JD,Haverich A,Kutschka I

更新日期：2014-11-01 00:00:00

abstract：:The PI3K/Akt signaling pathway has been implicated in playing an important role in platelet activation during hemostasis and thrombosis involving platelet-matrix interaction and platelet aggregation. Its role in non-physiological shear stress (NPSS)-induced platelet activation relevant to high-shear blood contacting m...

journal_title：Artificial organs

authors： Chen Z,Li T,Kareem K,Tran D,Griffith BP,Wu ZJ

更新日期：2019-09-01 00:00:00

abstract：:In this study, we investigated the differences between pulsatile cardiopulmonary bypass (CPB) procedure and nonpulsatile CPB procedure in terms of their effects on hemolysis and deformability of red blood cells (RBCs) under various shear stress conditions. In order to research the effects on hemolysis and deformabilit...

journal_title：Artificial organs

authors： Kang YJ,Kim MG,Son KH,Lim CH,Son HS,Yoon SY,Kwon HS,Yang S

更新日期：2010-04-01 00:00:00

abstract：:Plasma, in an amount corresponding to 0.05 gm fibrinogen/Kg of body weight, was administered during one hour to defibrinogenated dogs subjected to extracorporeal circulation. Four blood filters included in the extracorporeal circuit were removed one by one at 30-minute intervals. The prefilter pressures rose gradually...

journal_title：Artificial organs

authors： Berglin E,Hansson HA,William-Olsson G

更新日期：1979-02-01 00:00:00

abstract：:The compliance problem represents a major obstacle in the development of implantable blood pumps. The motor-driven pumps are enclosed in an airtight casing with gas in the motor space. The trapped gas in the motor space either increases the load on the motor during systole or impedes blood sac filling. Potential solut...

journal_title：Artificial organs

authors： Lee S,Rosenberg G,Donachy JH,Wisman CB,Pierce WS

更新日期：1984-02-01 00:00:00

abstract：:This study evaluated the usefulness of the three-dimensional representation of electrocardiogram traces (3DECG) to reveal acute and gradual changes during a full session of hemodiafiltration (HDF) in end-stage renal disease (ESRD) patients. Fifteen ESRD patients were included (six men, nine women, age 46 ± 19 years ol...

journal_title：Artificial organs

authors： Rodriguez-Fernandez R,Infante O,Perez-Grovas H,Hernandez E,Ruiz-Palacios P,Franco M,Lerma C

更新日期：2012-06-01 00:00:00

abstract：:The determination of when to stop extracorporeal membrane oxygenation (ECMO) rests upon demonstration of the return of adequate cardiac function to support vital organs and permit subsequent recovery. In general, patients with myocardial stun will recover function within several days. Factors that limit recovery inclu...

journal_title：Artificial organs

authors： Steinhorn DM

更新日期：1999-11-01 00:00:00

abstract：:Percutaneous pulmonary valve implantation is a potential treatment for right ventricular outflow tract (RVOT) dysfunction. However, RVOT implantation site varies among subjects and the success of the procedure depends on RVOT morphology selection. The aim of this study was to use in vitro testing to establish percutan...

journal_title：Artificial organs

authors： Vismara R,Laganà K,Migliavacca F,Schievano S,Coats L,Taylor A,Bonhoeffer P

更新日期：2009-01-01 00:00:00

abstract：:An apparatus has been contructed to regulate ultrafiltration accurately during dialysis. The principle of the apparatus is that, per unit of time, exactly the same amount of dialysate is introduced into the dialyzer as is discharged from it. The apparatus consists of two isovolumetric pumps connected in line. The four...

journal_title：Artificial organs

authors： Flendrig JG,Carpay WM,Dekkers WT

更新日期：1978-05-01 00:00:00