Donkey pericardium compares favorably with commercial xenopericardia used in the manufacture of transcatheter heart valves.

Abstract:

:Transcatheter aortic valve implantation (TAVI) has gained considerable acceptance in the past decade due to its lower risks than conventional open-heart surgery. However, the deformation and delamination of the leaflets during the crimping procedure have raised questions about the durability and long-term serviceability of the pericardium tissue from which the leaflets are made. The collagen architecture, wall thickness and mechanical properties of donkey pericardium were investigated to assess its suitability as an alternative material for the manufacture of heart valves. Coupons sampled from different locations of donkey pericardium were investigated. Bovine, equine, and porcine pericardium specimens served as controls. The donkey pericardium had a similar surface morphology to that of the control pericardia except for the wavy topology on both the fibrous and serous sides. The average thickness of donkey pericardium (ca. 120 µm) was significantly lower than that from bovine (375 µm) and equine (410 µm), but slightly higher than that from porcine (99 µm) specimens. The interlaced wavy collagen bundles in the pericardium were composed of collagen fibers about 100 nm in diameter. This unique structure ensures that the donkey pericardium has a comparable ultimate tensile strength (UTS) and a much higher failure strain than the commercial pericardia used for the manufacture of heart valves. The donkey pericardium has an organized wavy collagen bundle architecture similar to that of bovine pericardium and has a satisfactory UTS and high failure strain. The thin and strong donkey pericardium might be a good candidate valve leaflet material for TAVI.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Mao J,Rassoli A,Tong Y,Rouse EN,Le-Bel G,How D,Germain L,Fatouraee N,Zhang Z,Reed RR,Guidoin R

doi

10.1111/aor.13503

subject

Has Abstract

pub_date

2019-10-01 00:00:00

pages

976-987

issue

10

eissn

0160-564X

issn

1525-1594

journal_volume

43

pub_type

杂志文章
  • Permanent cardiac pacing after cardiac operations.

    abstract::From January 1980 through December 1990, implantation of a permanent pacemaker was performed in 34 patients following open heart surgery. The patients were divided into two groups according to the clinical indications for implantation of permanent pacemakers. Group 1 (9 patients) had surgical atrioventricular block, a...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1993.tb00591.x

    authors: Otaki M

    更新日期:1993-05-01 00:00:00

  • Flow balance between the left and right cardiac output of an eccentric roller type total artificial heart.

    abstract::We have made an eccentric roller type total artificial heart (ERTAH). The ERTAH is a positive-displacement device comparable to a DeBakey roller pump. Its left and right outputs are determined by the size of its blood chambers, and the ratio of its left and right output is almost constant. We focused on an interatrial...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1999.06414.x

    authors: Wada H,Fukunaga S,Watari M,Sakai H,Sugawara Y,Ochikubo H,Imai K,Shibamura H,Orihashi K,Sueda T,Matsuura Y

    更新日期:1999-08-01 00:00:00

  • Physical testing of elastomers for cardiovascular applications.

    abstract::There are presently no short-term in vitro fatigue tests available that can predict long-term in vivo performance of elastomers in physiological environments. Thus, the introduction of new and better elastomers for cardiovascular applications is hampered in the development stage by lack of data about which materials s...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1983.tb04162.x

    authors: McMillin CR

    更新日期:1983-02-01 00:00:00

  • Is the New Infant Jarvik 2015 Suitable for Patients

    abstract::Our aim was to study the feasibility of implanting the Infant Jarvik 2015 in patients weighing less than 8 kg. The Infant Jarvik 2015 left ventricular assist device (LVAD) was tested in a hybrid simulator of the cardiovascular system reproducing specific patients' hemodynamics for different patient weights (2-7 kg). F...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13302

    authors: Di Molfetta A,Zielinski K,Ferrari G,Kozarski M,Okrzeja P,Iacobelli R,Filippelli S,Perri G,Darowski M,Massetti M,Jarvik R,Amodeo A

    更新日期:2019-01-01 00:00:00

  • The type of aortic cannula and membrane oxygenator affect the pulsatile waveform morphology produced by a neonate-infant cardiopulmonary bypass system in vivo.

    abstract::Although the debate still continues over the effectiveness of pulsatile versus nonpulsatile perfusion, it has been clearly proven that there are several significant physiological benefits of pulsatile perfusion during cardiopulmonary bypass (CPB) compared to nonpulsatile perfusion. However, the components of the extra...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1998.06017.x

    authors: Undar A,Lodge AJ,Daggett CW,Runge TM,Ungerleider RM,Calhoon JH

    更新日期:1998-08-01 00:00:00

  • Fluid-Structure Interactions Analysis of Shear-Induced Modulation of a Mesenchymal Stem Cell: An Image-Based Study.

    abstract::Although effects of biochemical modulation of stem cells have been widely investigated, only recent advances have been made in the identification of mechanical conditioning on cell signaling pathways. Experimental investigations quantifying the micromechanical environment of mesenchymal stem cells (MSCs) are challengi...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12547

    authors: Ghaemi RV,Vahidi B,Sabour MH,Haghighipour N,Alihemmati Z

    更新日期:2016-03-01 00:00:00

  • Effect of moisture on and kinetic features of the ultrafiltration rate of dialysis membrane.

    abstract::The kinetic features of ultrafiltration of cellulose dialysis membrane stored under various humidity and temperature conditions were studied to obtain basic information of shelf-life characteristics of dialyzers. The ultrafiltration rate (UFR) decreased with time and the UFR-time curve suggested that the UFR would app...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1981.tb04003.x

    authors: Sato H,Kidaka T

    更新日期:1981-08-01 00:00:00

  • Development of cellulose-DNA immunoadsorbent.

    abstract::The aim of this study was to prepare a DNA immunoadsorbent for the specific, extracorporeal removal of anti-DNA antibodies from the blood of patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Two kinds of cellulose beads were applied as a carrier. Calf thymus DNA was covalently coupled to ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2002.06721.x

    authors: Kong D,Schuett W,Dai J,Kunkel S,Holtz M,Yamada R,Yu Y,Klinkmann H

    更新日期:2002-02-01 00:00:00

  • Outcome analysis for prediction of intraaortic balloon pump support failure and long-term survival in high-risk patients undergoing mitral valve surgery.

    abstract::The outcome predictors of intra-aortic balloon pump (IABP) in patients who undergo mitral valve surgery remain unknown. This study aimed to retrospectively review valvular surgery in patients who received an IABP to identify the predictors of failure of IABP support and anticipate the necessary therapy. This retrospec...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13669

    authors: Liang M,Wang C,Feng K,Chen G,Wang K,Wu Z

    更新日期:2020-08-01 00:00:00

  • Noninvasive average flow estimation for an implantable rotary blood pump: a new algorithm incorporating the role of blood viscosity.

    abstract::The effect of blood hematocrit (HCT) on a noninvasive flow estimation algorithm was examined in a centrifugal implantable rotary blood pump (iRBP) used for ventricular assistance. An average flow estimator, based on three parameters, input electrical power, pump speed, and HCT, was developed. Data were collected in a ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2007.00339.x

    authors: Malagutti N,Karantonis DM,Cloherty SL,Ayre PJ,Mason DG,Salamonsen RF,Lovell NH

    更新日期:2007-01-01 00:00:00

  • Effects of atrial arrhytmias on the regurgitation of a monoleaflet prosthetic heart valve.

    abstract::Many patients who receive a prosthetic heart valve also have or acquire cardiac arrhythmias. However, most in vitro studies of prosthetic valves examine them under normal rhythms. In this study, a monoleaflet prosthetic heart valve was tested in vitro under conditions that simulated normal sinus rhythm, first degree a...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2005.29101.x

    authors: Zapanta CM

    更新日期:2005-08-01 00:00:00

  • Anticoagulation with fondaparinux for hemodiafiltration in patients with heparin-induced thrombocytopenia: dose-finding study and safety evaluation.

    abstract::The optimal anticoagulation regimen for hemodialysis (HD) in patients with heparin-induced thrombocytopenia (HIT) has not been defined. Hemodiafiltration (HDF) adds a large convective component to HD, thereby changing the pharmacokinetics of most anticoagulants. Data on coagulation regimens for HDF are scant. We there...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12002

    authors: Mahieu E,Claes K,Jacquemin M,Evenepoel P,Op De Beek K,Bogaert AM,Kuypers D,Verhamme P,Meijers B

    更新日期:2013-05-01 00:00:00

  • Estimation of theophylline clearance during continuous arteriovenous hemofiltration.

    abstract::Pharmacologic agents and other non-protein-bound compounds smaller than 5,000 daltons have the potential to be removed by continuous arteriovenous hemofiltration (CAVH). A proposed method for estimating drug clearance by CAVH (ClCAVH) equates ultrafiltrate clearance to the product of the sieving coefficient and the av...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1990.tb02997.x

    authors: Horton MW,Godley PJ,Moore ES,Fineg J,Gillespie WR

    更新日期:1990-12-01 00:00:00

  • A New 2D Echocardiographic Approach to Evaluate the Membrane and Valve Movement of the Berlin Heart EXCOR VAD Chamber in Pediatric VAD Patients.

    abstract::The use of Berlin Heart EXCOR VAD (BH) is a validated therapy to bridge pediatric patients to heart transplant. Serial echocardiographic (ECHO) assessment of VAD patients is necessary to support patients' management. This work aims at developing an innovative strategy to evaluate the BH device functioning by ECHO and ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13122

    authors: Di Molfetta A,Iacobelli R,Ferrari G,Filippelli S,Perri G,Toscano A,Adorisio R,Guccione P,Amodeo A

    更新日期:2018-04-01 00:00:00

  • Reduction of driveline infections through doubled driveline tunneling of left ventricular assist devices.

    abstract::The durability of ventricular assist device (VAD) therapy improved steadily over the past years. However, driveline infections remain a challenge. To test whether an improved surgical implantation technique may lower the incidence of infections, we analyzed all patients receiving a VAD implantation in the years 2008 a...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12036

    authors: Fleissner F,Avsar M,Malehsa D,Strueber M,Haverich A,Schmitto JD

    更新日期:2013-01-01 00:00:00

  • Remote monitoring of left ventricular assist device parameters after HeartAssist-5 implantation.

    abstract::Although several left ventricular assist devices (LVADs) have been used widely, remote monitoring of LVAD parameters has been available only recently. We present our remote monitoring experience with an axial-flow LVAD (HeartAssist-5, MicroMed Cardiovascular, Inc., Houston, TX, USA). Five consecutive patients who were...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12144

    authors: Pektok E,Demirozu ZT,Arat N,Yildiz O,Oklu E,Eker D,Ece F,Ciftci C,Yazicioglu N,Bayindir O,Kucukaksu DS

    更新日期:2013-09-01 00:00:00

  • Influence of growth hormone on maintenance of capillary-like structures in an in vitro model of stromal vascular tissue--results from morphometric analysis.

    abstract::The in vitro development of a vascular stroma might be a solution for the engineering of vascularized tissues, however, in vitro stability of capillary-like structures is limited. In order to test the influence on maintenance of capillary-like structures, human growth hormone (hGH) was added in concentrations of 0.5, ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2005.29057.x

    authors: Frerich B,Kurtz-Hoffmann J,Lindemann N

    更新日期:2005-04-01 00:00:00

  • Surface modification of silicone rubber membrane by plasma induced graft copolymerization as artificial cornea.

    abstract::In this study a highly biocompatible polymer membrane was prepared by surface modification. An artificial cornea was also developed for clinical applications. Silicone rubber (SR) membrane was grafted with hydrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA) and acrylic acid by plasma induced grafted polyme...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1996.tb00661.x

    authors: Hsiue GH,Lee SD,Chang PC

    更新日期:1996-11-01 00:00:00

  • Microbial and endotoxin contamination in water and dialysate in the central United States.

    abstract::The purified water supplies and randomly selected dialysates of 51 chronic and acute dialysis centers in the central United States were surveyed to assess the relative risks to dialysis patients from microbial and endotoxin contamination. A culture medium more sensitive than those generally employed in routine quality...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1990.tb01601.x

    authors: Klein E,Pass T,Harding GB,Wright R,Million C

    更新日期:1990-04-01 00:00:00

  • A Pseudo-One Compartment Model of Phosphorus Kinetics During Hemodialysis: Further Supporting Evidence.

    abstract::A pseudo-one compartment model has been proposed to describe phosphorus kinetics during hemodialysis and the immediate post-dialysis period. This model assumes that phosphorus mobilization from tissues is proportional to the difference between the pre-dialysis serum concentration (a constant) and the instantaneous ser...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12897

    authors: Leypoldt JK,Agar BU,Cheung AK,Bernardo AA

    更新日期:2017-11-01 00:00:00

  • The monomeric formulation optimization of dental composite: mechanical and kinetic studies.

    abstract::The optimization of the monomer composition, using a polymerization kinetic study and the mechanical behavior study of the composites, was the principal objective of this work. The monomeric mixture analyzed is a part of the composite that has been in development at the University of Campinas, Brazil. Parameters such ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2003.07250.x

    authors: López Palacio RE,de Carvalho Zavaglia CA

    更新日期:2003-05-01 00:00:00

  • Usability and safety of ventricular assist devices: human factors and design aspects.

    abstract::The purpose of this study was the investigation of the usability and ergonomics of ventricular assist devices (VADs) in everyday usage. Patients with four different VAD types were observed. After implantation, instruction, and discharge from the hospital, the patients returned on a regular basis to the outpatient clin...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00844.x

    authors: Geidl L,Zrunek P,Deckert Z,Zimpfer D,Sandner S,Wieselthaler G,Schima H

    更新日期:2009-09-01 00:00:00

  • Superior mesenteric artery mycotic aneurysm in patients with left ventricular assist device support and intravenous drug abuse.

    abstract::Mycotic aneurysm of the superior mesenteric artery (SMA) is one of the complications associated with infective endocarditis. However, there are no previous case reports in the literature describing mycotic SMA aneurysm after left ventricular assist device (LVAD) implantation. We describe the case of a 31-year-old male...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2011.01250.x

    authors: Motomura T,Bruckner B,Leon-Becerril J,Anaya-Ayala JE,de Rienzo-Madero B,Bismuth J,Bunge R,Irwin S,Loebe M

    更新日期:2011-07-01 00:00:00

  • The role of PI3K/Akt signaling pathway in non-physiological shear stress-induced platelet activation.

    abstract::The PI3K/Akt signaling pathway has been implicated in playing an important role in platelet activation during hemostasis and thrombosis involving platelet-matrix interaction and platelet aggregation. Its role in non-physiological shear stress (NPSS)-induced platelet activation relevant to high-shear blood contacting m...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13465

    authors: Chen Z,Li T,Kareem K,Tran D,Griffith BP,Wu ZJ

    更新日期:2019-09-01 00:00:00

  • Evaluation of chitosan-alginate-hyaluronate complexes modified by an RGD-containing protein as tissue-engineering scaffolds for cartilage regeneration.

    abstract::In this study, a series of natural biodegradable materials in the form of chitosan (C)-alginate (A)-hyaluronate (H) complexes are evaluated as tissue-engineering scaffolds. The weight ratio of C/A is 1 : 1 or 1 : 2. Sodium hyaluronate is mixed in 2%. The complexes can be cast into films or fabricated as scaffolds. The...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2004.00046.x

    authors: Hsu SH,Whu SW,Hsieh SC,Tsai CL,Chen DC,Tan TS

    更新日期:2004-08-01 00:00:00

  • Influence of flow design on microcirculation in conditions of undulation pump-left ventricle assist device testing.

    abstract::To study the microvessels in bulbar conjunctiva, we conducted an experiment in goat with a pneumatically driven left heart bypass pump, which was replaced with an undulation pump-left ventricle assist device for 9 days. Three flow patterns were tested: complete pulsatile, continuous, and percentage of pulsatile. We st...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2006.00244.x

    authors: Dobsák P,Novakova M,Baba A,Vasku J,Isoyama T,Saito I,Abe Y,Chinzei T,Imachi K

    更新日期:2006-06-01 00:00:00

  • Judicious usage of estrogen/progesterone for angiodysplasia.

    abstract::We recently experienced a case of a female hemodialysis patient with multiple intestinal angiodysplasias. In 2001, she complained of melena, and angiographic embolization halted bleeding from ileum angiodysplasia. In 2002, she again complained of black stool. Abdominal angiography found jejunum angiodysplasia, and pha...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2004.29003.x

    authors: Takenaka T,Kanno Y,Suzuki H

    更新日期:2005-01-01 00:00:00

  • Treatment of severe hyperlipidemia: six years' experience with low-density lipoprotein apheresis.

    abstract::In total, 30 patients suffering from familial hypercholesterolemia, resistant to diet and lipid-lowering drugs, were treated for up to 6 years (3.6 + or - 1.6; range, 0.2-6.8 years) with low-density lipoprotein (LDL) apheresis. Three different systems were used; the dextran sulfate adsorption system (Kaneka) for 27 of...

    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1525-1594.1996.tb04455.x

    authors: Bambauer R,Schiel R,Latza R,Klinkmann J

    更新日期:1996-04-01 00:00:00

  • Multifunctional implantable nerve stimulator for cardiac assistance by skeletal muscle.

    abstract::Different methods are used, clinically and experimentally, to assist severely impaired heart function by means of skeletal muscle. The efficiency of these methods is restricted by skeletal muscle losing strength after transpositioning and during conditioning and not being sufficiently resistant to fatigue. This is mai...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1999.06258.x

    authors: Lanmüller H,Sauermann S,Unger E,Schnetz G,Mayr W,Bijak M,Girsch W

    更新日期:1999-04-01 00:00:00

  • Dialysis reduces portal pressure in patients with chronic hepatitis C.

    abstract::The purpose of this study was to characterize changes in hepatic venous pressures in patients with chronic hepatitis C. The histology and laboratory data from patients with chronic hepatitis C who underwent a transjugular liver biopsy (TJLB) and hepatic venous pressure gradient measurement were analyzed. Portal hypert...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00925.x

    authors: Khurana S,Simcox T,Twaddell W,Drachenberg C,Flasar M

    更新日期:2010-07-01 00:00:00