Microbial and endotoxin contamination in water and dialysate in the central United States.

Abstract:

:The purified water supplies and randomly selected dialysates of 51 chronic and acute dialysis centers in the central United States were surveyed to assess the relative risks to dialysis patients from microbial and endotoxin contamination. A culture medium more sensitive than those generally employed in routine quality assurance assays was used for recovery of bacteria from water. With this medium, 35.3% of the water samples and 19% of the dialysate samples were out of compliance with the Association for the Advancement of Medical Instrumentation (AAMI) standards: 200 and 2,000 colony forming units (CFU)/ml, respectively. There was no correlation observed between the type of water purification system or the frequency of disinfection of the system and the bacterial and endotoxin contamination levels. There was also no correlation found between the bacterial and fungal CFU per ml and the endotoxin concentration per ml (EU/ml). It is recommended that more sensitive culturing methods be used to provide adequate bacterial monitoring of dialysate center water supplies. Dialysis centers should monitor endotoxin in dialysate on a regular schedule and immediately after any endotoxemic-like patient reactions. Yeast and fungi were observed in 10% and 64% of the water systems, respectively. Dialysate was contaminated by yeast and fungi in 30% and 70% of the centers, respectively. The concentrations of these microbes in both fluids were much lower than bacteria. However, they were observed often enough to warrant further investigation of their impact on the well-being of dialysis patients.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Klein E,Pass T,Harding GB,Wright R,Million C

doi

10.1111/j.1525-1594.1990.tb01601.x

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

85-94

issue

2

eissn

0160-564X

issn

1525-1594

journal_volume

14

pub_type

杂志文章
  • A reduced priming system.

    abstract::Cardiopulmonary bypass (CPB), an integral part of valve surgery, is known to cause hemodilution, which can lead to a need for blood transfusion as well as a systemic inflammatory reaction. Our aim was to evaluate a reduced priming (RP) system for CPB with regard to clinical outcomes in patients undergoing valve surger...

    journal_title:Artificial organs

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1525-1594.2006.00275.x

    authors: Sato K,Namura O,Sogawa M,Shimada K,Tosaka Y,Hayashi J

    更新日期:2006-08-01 00:00:00

  • Influence of middle molecules on the anemia of uremic patients.

    abstract::To evaluate their toxicity at the cellular level, middle molecules from uremic serum were incubated with erythrocytes from healthy subjects and the activity of the enzyme Delta-aminolevulinic acid dehydrase (D-ALA-D) and peroxidative hemolysis were investigated. Uremic middle molecules caused a significant decrease of...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1978.tb01626.x

    authors: Leber HW,Spiegelhalter R,Ulm A,Goubeaud G,Rawer P

    更新日期:1978-11-01 00:00:00

  • Changes in Total Cardiac Output and Oxygen Extraction During Exercise in Patients Supported With an HVAD Left Ventricular Assist Device.

    abstract::Following implantation of a left ventricular assist device (LVAD), acceptable functional performance is now being achieved; however, peak VO2 and peak work load (watts) remain considerably limited. Maximum physical capacity is essentially dependent on generated cardiac output (CO) and arteriovenous oxygen difference (...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13102

    authors: Schmidt T,Bjarnason-Wehrens B,Mommertz S,Hannig M,Schulte-Eistrup S,Willemsen D,Reiss N

    更新日期:2018-07-01 00:00:00

  • Survival of patients on chronic hemodialysis: single center experience.

    abstract::Patient survival from our hemodialysis (HD) center over the past 11 years was analyzed. Four hundred four patients, 212 female and 192 male, were treated by chronic intermittent HD. Patients were offered standard acetate-cellulosic membranes of 1.0-1.3 m2. During this period 181 patients died. One hundred three patien...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1999.06291.x

    authors: Polenakovik M,Sikole A,Stojcev N,Spasovski G,Amitov V,Nikolov V,Masin G,Klinkmann H

    更新日期:1999-01-01 00:00:00

  • A compact highly efficient and low hemolytic centrifugal blood pump with a magnetically levitated impeller.

    abstract::A magnetically levitated (maglev) centrifugal blood pump (CBP), intended for use as a ventricular assist device, needs to be highly durable and reliable for long-term use without any mechanical failure. Furthermore, maglev CBPs should be small enough to be implanted into patients of various size and weight. We have de...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2006.00202.x

    authors: Asama J,Shinshi T,Hoshi H,Takatani S,Shimokohbe A

    更新日期:2006-03-01 00:00:00

  • Intravascular micropump for augmented liver perfusion: first in vivo experience.

    abstract::The aim of this study was to assess the in vivo performance of a new microaxial rotary blood pump developed for long-term intraportal implantation. The pump, measuring 7 mm in diameter, has a single stage impeller and is powered by a microelectric motor. The pump was implanted into the portal vein in 13 large white pi...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2001.06772.x

    authors: Havlík R,Kerkhoffs W,Jiao LR,Schumacher O,Reul H,Habib N

    更新日期:2001-05-01 00:00:00

  • Development of a flow estimation and control system of an implantable centrifugal blood pump for circulatory assist.

    abstract::A bypass flow rate estimation and control system (BECS) for an implantable centrifugal blood pump (ICBP) has been developed in our institute. The estimated flow rate (EF) of the ICBP was derived from the electric power consumption, the rotating speed of a motor, and the blood viscosity presumed by the hematocrit and b...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1998.06130.x

    authors: Wakisaka Y,Okuzono Y,Taenaka Y,Chikanari K,Endo S,Masuzawa T,Takano H

    更新日期:1998-06-01 00:00:00

  • A hybrid mock circulation loop for a total artificial heart.

    abstract::Rotary blood pumps are emerging as a viable technology for total artificial hearts, and the development of physiological control algorithms is accelerated with new evaluation environments. In this article, we present a novel hybrid mock circulation loop (HMCL) designed specifically for evaluation of rotary total artif...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12380

    authors: Nestler F,Bradley AP,Wilson SJ,Timms DL,Frazier OH,Cohn WE

    更新日期:2014-09-01 00:00:00

  • Separation of the natural atria in experimental implantation of total artificial heart.

    abstract::Atrial connections in a single-unit total artificial heart (TAH) may be difficult to make because of the rigidity of the device and the fixed position of the atrial inlets. We developed a technique to separate the natural atrial borders in an experimental implantation of a unitary TAH. In this technique, the interatri...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1995.tb02442.x

    authors: Frazier OH,Matsuwaka R,Parnis SM,Furusho N,McGee MG,Fuqua JM

    更新日期:1995-08-01 00:00:00

  • Development of a Tissue-Engineered Artificial Ligament: Reconstruction of Injured Rabbit Medial Collateral Ligament With Elastin-Collagen and Ligament Cell Composite Artificial Ligament.

    abstract::Ligament reconstruction using a tissue-engineered artificial ligament (TEAL) requires regeneration of the ligament-bone junction such that fixation devices such as screws and end buttons do not have to be used. The objective of this study was to develop a TEAL consisting of elastin-coated polydioxanone (PDS) sutures c...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13124

    authors: Hirukawa M,Katayama S,Sato T,Inoue K,Niwa K,Ito N,Hattori T,Hosoi T,Unno H,Suzuki Y,Hasegawa M,Miyamoto K,Horiuchi T

    更新日期:2018-07-01 00:00:00

  • Comparison of four methods of cleaning hollow-fiber dialyzers for reuse.

    abstract::Four methods of cleaning hollow-fiber artificial kidneys (HFAKs) for reuse were compared in a prospective study. Each cleaning method was randomly assigned and HFAKs were reused until volume loss was greater than or equal to 15 ml, unless discarded for other reasons. HFAKs cleaned with 0.3 M sodium hydroxide averaged ...

    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1525-1594.1986.tb02602.x

    authors: Dennis MB Jr,Vizzo JE,Cole JJ,Westendorf DL,Ahmad S

    更新日期:1986-12-01 00:00:00

  • Reciprocal influences between ambulatorial peritoneal dialysis and pulmonary function.

    abstract::The aim of this study was to verify if dialysis solution volumes used in patients on continuous ambulatory peritoneal dialysis (CAPD) interfere with pulmonary function and if the pulmonary volumes interfere with the lymphatic absorption of the peritoneal cavity. We submitted 10 CAPD patients with a mean age of 48 +/- ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2001.06904.x

    authors: Marmanillo CG,Pecoits-Filho RF,Romão JE Jr,Kakehashi ET,Sabbaga E,Marcondes M,Abensur H

    更新日期:2001-11-01 00:00:00

  • Biodegradation and biocompatibility of polyorganophosphazene.

    abstract::We investigated biodegradation and biocompatibility of poly(organophosphazenes). We prepared poly(organophosphazenes) having different side chain groups. The blood compatibility of poly(organophosphazenes) containing fluorinated side groups, poly(bis[trifluoroethoxy]phosphazene) (PbFP) and poly([trifluoroethoxy][ethyl...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2002.07029.x

    authors: Kawakami H,Kanezaki S,Sudo M,Kanno M,Nagaoka S,Kubota S

    更新日期:2002-10-01 00:00:00

  • Donkey pericardium compares favorably with commercial xenopericardia used in the manufacture of transcatheter heart valves.

    abstract::Transcatheter aortic valve implantation (TAVI) has gained considerable acceptance in the past decade due to its lower risks than conventional open-heart surgery. However, the deformation and delamination of the leaflets during the crimping procedure have raised questions about the durability and long-term serviceabili...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.13503

    authors: Mao J,Rassoli A,Tong Y,Rouse EN,Le-Bel G,How D,Germain L,Fatouraee N,Zhang Z,Reed RR,Guidoin R

    更新日期:2019-10-01 00:00:00

  • Ethylene oxide sensitivity in hemodialysis patients.

    abstract::Sera from 138 patients who had experienced hypersensitivity-type reactions while on hemodialysis (reactors) were examined retrospectively by the radioallergosorbent test (RAST) for specific IgE antibody to ethylene oxide (ETO). Seventy-eight hemodialysis patients without a history of reaction were also evaluated as co...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1987.tb02638.x

    authors: Pearson F,Bruszer G,Lee W,Sagona M,Sargent H,Woods E,Dolovich J,Caruana R

    更新日期:1987-04-01 00:00:00

  • Cooling device for bradycardia based on Peltier element for accurate anastomosis of off-pump coronary artery bypass grafting.

    abstract::Upon introducing off-pump coronary artery bypass grafting (CABG), the indications for CABG were expanded to include patients who previously had no operative indications. For accurate anastomosis, various devices and methods have been developed. Bradycardia is easily induced by drug administration. However, this method...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2002.07087.x

    authors: Kuniyoshi Y,Koja K,Miyagi K,Shimoji M,Uezu T,Arakaki K,Yamashiro S,Mabuni K,Senaha S

    更新日期:2002-10-01 00:00:00

  • Myristoyl gelatin as a sealant for Dacron vascular prostheses.

    abstract::Myristoyl gelatin (MG) retains its gel structure at temperatures above body temperature without any crosslinking. As a coating material, MG adheres well to polyester fibers, and the outermost layers of the sealant that are in contact with blood or surrounding tissue become hydrophilic. We produced MG-impregnated knitt...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1997.tb00363.x

    authors: Sasajima T,Inaba M,Azuma N,Goh K,Koshiko S,Kubo Y,Miyamoto K,Tokita M,Komai T

    更新日期:1997-04-01 00:00:00

  • Preservation of human saphenous vein against reactive oxygen species-induced oxidative stress by green tea polyphenol pretreatment.

    abstract::The injurious effects of reactive oxygen species on venous tissues and the potential protective role played by green tea polyphenol (GTPP) on human saphenous veins were investigated. Oxidative stress was induced exogenously in the vein segments, either by adding 0.8 or 1.6 M of H2O2, or by using 80 or 160 U/L of xanth...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2003.07163.x

    authors: Han DW,Suh H,Park YH,Cho BK,Hyon SH,Park JC

    更新日期:2003-12-01 00:00:00

  • A nonsurgical technique for blood access in extracorporeal affinity adsorption of antibodies in rats.

    abstract::Monoclonal antibodies for targeting cytotoxic conjugates to tumor cells are currently being evaluated together with extracorporeal affinity adsorption. The aim of the adsorption was to reduce undesired side effects in normal organs and to increase the tumor-to-normal tissue ratios. This technique is also applicable to...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2007.00380.x

    authors: Mårtensson L,Nilsson R,Sjögren HO,Strand SE,Tennvall J

    更新日期:2007-04-01 00:00:00

  • Pulsatile culture of a poly(DL-lactic-co-glycolic acid) sandwiched cell/hydrogel construct fabricated using a step-by-step mold/extraction method.

    abstract::To overcome the weak mechanical properties of cell/hydrogel composites, a poly(DL-lactic-co-glycolic acid) sandwiched adipose-derived stem cell (ADSC)/fibrin construct was fabricated using a step-by-step mold/extraction method to generate the middle smooth muscle layer of natural blood vessels. A pulse bioreactor with...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2010.01137.x

    authors: Wang X,Sui S

    更新日期:2011-06-01 00:00:00

  • Systemic consequences of ventricular assist devices: alterations of coagulation, immune function, inflammation, and the neuroendocrine system.

    abstract::Implantable ventricular assist devices have proven efficacious as a bridge to transplantation and as a bridge to recovery. Although current indications for use of assist devices are somewhat limited, they are likely to expand in the upcoming years, including their use as destination therapy for end-stage heart failure...

    journal_title:Artificial organs

    pub_type: 杂志文章,评审

    doi:10.1046/j.1525-1594.2002.07122.x

    authors: Hampton CR,Verrier ED

    更新日期:2002-11-01 00:00:00

  • Anemia in acute renal failure: role for erythropoiesis-stimulating proteins?

    abstract::The use of recombinant human erythropoietin (rHuEpo) has revolutionized anemia management of early and late stages of chronic kidney disease. Darbopoietin is also now available for the treatment of anemia of chronic kidney disease. In addition, rHuEpo has been used for the treatment of anemia observed in critical illn...

    journal_title:Artificial organs

    pub_type: 杂志文章,评审

    doi:10.1046/j.1525-1594.2003.07287.x

    authors: Liangos O,Pereira BJ,Jaber BL

    更新日期:2003-09-01 00:00:00

  • Measurement of the closing behavior of the björk-shiley monoleaflet mechanical heart valve with an electrohydraulic total artificial heart.

    abstract::When cavitation occurs near a material surface of a mechanical heart valve (MHV), pits on the surface of the MHV and hemolysis are caused. Therefore, it is very important to investigate the possibility of the occurrence of cavitation in an MHV. To study the possibility of cavitation occurrence in a 25 mm Björk-Shiley ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2003.06981.x

    authors: Lee H,Tsukiya T,Homma A,Taenaka Y,Tatsumi E,Takano H

    更新日期:2003-08-01 00:00:00

  • Feasibility of extracorporeal on-line large-scale plasma adsorptions on protein A-sepharose columns in cancer patients.

    abstract::The feasibility of extracorporeal adsorption of 1.5-3 L plasma on protein A-Sepharose was investigated in six patients with advanced cancer. Anticoagulation with heparin was associated with respiratory distress syndrome in two patients, most likely caused by complement activation as indicated by a transient leukopenia...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1984.tb04247.x

    authors: Wallmark A,Grubb A,Freiburghaus C,Flodgren P,Husberg B,Lindholm T,Lindström C,Thysell H,Sjögren HO

    更新日期:1984-02-01 00:00:00

  • Oxidative Stress Increases Erythrocyte Sensitivity to Shear-Mediated Damage.

    abstract::Patients receiving mechanical circulatory support often present with heightened inflammation and free radical production associated with pre-existing conditions in addition to that which is due to blood interactions with nonbiological surfaces. The aim of this experimental laboratory study was to assess the deformabil...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12997

    authors: McNamee AP,Horobin JT,Tansley GD,Simmonds MJ

    更新日期:2018-02-01 00:00:00

  • A computerized model to analyze transcellular fluid shift during hemofiltration.

    abstract::Using urea and inulin as markers, we have developed a simple method to calculate intracellular and extracellular fluid volume in patients before and after hemofiltration therapy. During conventional hemofiltration using substitution fluid with a Na+ concentration of 140 mEq/L, a decrease in extracellular fluid volume ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1982.tb04054.x

    authors: Kimura G,Satani M,Kojima S,Kuroda K,Itoh K,Ikeda M

    更新日期:1982-02-01 00:00:00

  • Characteristics of chronically paced cardiac functions in the congenital complete atrioventricular block.

    abstract::Characteristics of morphology, cardiac function, and cardiac reserve at late state were evaluated at rest, by changing the pacing rates, and after exercise in patients with ventricular pacemakers for isolated congenital complete atrioventricular block. Heart size was reduced statistically after pacemaker implantation,...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1987.tb02667.x

    authors: Nawa S,Kioka Y,Shimizu A,Tsuji H,Miyachi Y,Ebara K,Kino K,Shigenobu M,Murakami T,Senoo Y

    更新日期:1987-06-01 00:00:00

  • Estimation of the native cardiac output from a rotary blood pump flow: in vitro study.

    abstract::The rotary blood pump will be an implantable left ventricular assist device (LVAD) in the near future. However, the best control method and the interrelationship between the rotary blood pump and native heart functions are unclear. An estimation was made of the native heart cardiac output from the change of an LVAD's ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1998.06127.x

    authors: Nakata K,Ohashi Y,Tayama E,Ohtsuka G,Takami Y,Mueller J,Glueck J,Nosé Y

    更新日期:1998-05-01 00:00:00

  • Implantable volume monitor and miniaturized stimulator dedicated to bladder control.

    abstract::This paper describes a new miniaturized implantable bladder controller that is composed of 4 main parts: a volume monitoring device based on the tomography approach, a fully programmable miniaturized central processor and stimulator, a bidirectional data and power link, and an external controller. The proposed system ...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:

    authors: Sawan M,Arabi K,Provost B

    更新日期:1997-03-01 00:00:00

  • The OregonHeart Total Artificial Heart: Design and Performance on a Mock Circulatory Loop.

    abstract::Widespread use of heart transplantation is limited by the scarcity of donor organs. Total artificial heart (TAH) development has been pursued to address this shortage, especially to treat patients who require biventricular support. We have developed a novel TAH that utilizes a continuously spinning rotor that shuttles...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12959

    authors: Glynn J,Song H,Hull B,Withers S,Gelow J,Mudd J,Starr A,Wampler R

    更新日期:2017-10-01 00:00:00