Noninvasive average flow estimation for an implantable rotary blood pump: a new algorithm incorporating the role of blood viscosity.

abstract：:The aim of this study was to prepare a DNA immunoadsorbent for the specific, extracorporeal removal of anti-DNA antibodies from the blood of patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Two kinds of cellulose beads were applied as a carrier. Calf thymus DNA was covalently coupled to ...

journal_title：Artificial organs

authors： Kong D,Schuett W,Dai J,Kunkel S,Holtz M,Yamada R,Yu Y,Klinkmann H

更新日期：2002-02-01 00:00:00

abstract：:Temporary extracorporeal membrane oxygenation (ECMO) has been established as an essential part of therapy in patients with pulmonary or cardiac failure. As physiological gaseous exchange is artificially altered in this patient group, it is debatable whether a (13) C-breath test can be carried out. In this proof of tec...

journal_title：Artificial organs

authors： Bednarsch J,Menk M,Malinowski M,Weber-Carstens S,Pratschke J,Stockmann M

更新日期：2016-07-01 00:00:00

abstract：:We have made an eccentric roller type total artificial heart (ERTAH). The ERTAH is a positive-displacement device comparable to a DeBakey roller pump. Its left and right outputs are determined by the size of its blood chambers, and the ratio of its left and right output is almost constant. We focused on an interatrial...

journal_title：Artificial organs

authors： Wada H,Fukunaga S,Watari M,Sakai H,Sugawara Y,Ochikubo H,Imai K,Shibamura H,Orihashi K,Sueda T,Matsuura Y

更新日期：1999-08-01 00:00:00

abstract：:As a preliminary investigation to establish a cryopreservation method suited for bioartificial livers (BALs), three-dimensional (3-D) cryopreservation experiments with fibroblasts were performed, in which the cells were firstly seeded into a porous scaffold, and the scaffold containing the cells was then cryopreserved...

journal_title：Artificial organs

authors： Miyoshi H,Ehashi T,Ohshima N,Jagawa A

更新日期：2010-07-01 00:00:00

abstract：:Liposome-encapsulated hemoglobin (LEH) was proven to be protective in cerebral ischemia/reperfusion injury. The present study evaluated LEH in a rat model of permanent middle cerebral artery (MCA) occlusion to clarify its effect during ischemia and reperfusion. Five minutes after thread occlusion of the MCA, rats were...

journal_title：Artificial organs

authors： Kawaguchi AT,Kurita D,Furuya H,Yamano M,Ogata Y,Haida M

更新日期：2009-02-01 00:00:00

abstract：:The growing practice of dialyzer reuse in recent years is mainly based on medical and economic considerations. However, adverse reactions such as immunohemolytic anemia due to anti-Nform antibody associated with dialyzer reuse have been reported. In this study, scanning electron microscopy and cytologic staining were ...

journal_title：Artificial organs

authors： Ng YY,Yang AH,Wong KC,Lan HY,Hung TL,Kerr PG,Huang TP

更新日期：1996-01-01 00:00:00

abstract：:To develop an effective hybrid bioartificial liver (BAL) device, the material of the scaffold is very important to support hepatocytes that have both growth ability and hepatic differentiated functions. In this study we used paper (Kimwipe, Kimberly-Clark Corp., Roswell, GA, U.S.A.) as a scaffold. Primary hepatocytes ...

journal_title：Artificial organs

authors： Mizuguchi T,Mitaka T,Sato F,Mochizuki Y,Hirata K

更新日期：2000-04-01 00:00:00

abstract：:Effect of hemodialysis (HD) on some indices of immune response was studied in nine chronic uremics. Total lymphocyte, OKT4+, and OKT8+ cell numbers significantly decreased during the first 20 min of HD, and they were decreased till the third hour of the procedure, whereas the OKT4+/OKT8+ cell number ratio did not chan...

journal_title：Artificial organs

authors： Tchórzewski H,Luciak M,Trznadel K,Majewska E,Pokoca L

更新日期：1989-06-01 00:00:00

abstract：:The aim of this study was to compare patients with severe biventricular heart failure who underwent Berlin Heart Excor implantation with (cardiogenic shock [CS] status) or without the need for preoperative extracorporeal life support (ECLS) as a bridge to long-term device. A total of 40 consecutive patients with sever...

journal_title：Artificial organs

authors： Weymann A,Farag M,Sabashnikov A,Fatullayev J,Zeriouh M,Schmack B,Arif R,Müller F,Alt C,Raake P,Prakash Patil N,Popov AF,Rüdiger Simon A,Karck M,Ruhparwar A,Heidelberg-Cologne-Harefield Cardiothoracic Transplantation & Mecha

更新日期：2017-06-01 00:00:00

abstract：:The trend in neural prostheses using selective nerve stimulation for electrical stimulation therapies is headed toward single-part systems having a large number of working electrodes (WEs), each of which selectively stimulate neural tissue or record neural response (NR). The present article reviews the electrochemical...

journal_title：Artificial organs

authors： Pečlin P,Mehle A,Karpe B,Rozman J

更新日期：2015-10-01 00:00:00

abstract：:A multi-compartment capillary membrane culture model with independently perfused three-dimensionally woven capillaries was developed for immobilization of hepatocytes in bioreactors. This enables spatial restructuring of cells and enhanced mass transfer performance with more efficient oxygenation and metabolite exchan...

journal_title：Artificial organs

authors： Gerlach J,Schnoy N,Smith MD,Neuhaus P

更新日期：1994-03-01 00:00:00

abstract：:This study compares the effects of polyethylene glycol (PEG) modified bovine hemoglobin on vascular half-life and renal function in rabbits to those of unmodified bovine hemoglobin. Renal function was assessed by the measurement of the glomerular filtration rate, urinalysis, blood chemistries, hemoglobin (Hb) excretio...

journal_title：Artificial organs

authors： Conover CD,Gilbert CW,Shum KL,Shorr RG

更新日期：1997-08-01 00:00:00

abstract：:Aseptic joint loosening is a key factor that reduces the life span of arthroplasty. There are currently few effective treatments for joint loosening except surgical revision. We explored the inhibitory effects of tumor necrosis factor (TNF)-alpha-targeted small interfering RNA (siRNA) on particle-induced inflammatory ...

journal_title：Artificial organs

authors： Qin CQ,Ding Y,Huang DS,Xu J,Ma RF,Huang JB

更新日期：2011-07-01 00:00:00

abstract：:A 68-year-old woman with fulminant hepatic failure of unknown etiology was treated with a bioartificial liver assist device. Prior to treatment, she had a number of clinical and laboratory features that suggested a hopeless outcome. Treatment was associated with a dramatic change in her mental status, and her clinical...

journal_title：Artificial organs

authors： Sussman NL,Kelly JH

更新日期：1993-01-01 00:00:00

abstract：:It has been over 40 years since the initial clinical application of a cardiac pacemaker. Currently, approximately 300 per million patients in the United States and Europe are kept alive owing to the benefit of implantable pacemakers. Recently, the Japanese Cardiac Pacing Society and the Japanese Society of Artificial ...

journal_title：Artificial organs

authors： Kojima R

更新日期：1994-01-01 00:00:00

abstract：:With the goal of investigating artificial proprioception elicited by electrical stimulation, we have developed a tactile phi phenomenon-based stimulator. This two-channel microprocessed pulse amplitude modulation system generates two different envelope waveforms (triangular and elliptical) and allows programming and v...

journal_title：Artificial organs

authors： Nohama P,Lopes AV,Cliquet Júnior A

更新日期：1995-03-01 00:00:00

abstract：:Protein adsorption and platelet adhesion are two important biological processes arising at the blood prosthetic interface. The effect of certain antibiotics, namely, neomycin, gentamicin, ampicillin, penicillin-G, and streptomycin to modulate the albumin polycarbonate surface interaction was investigated using 125I al...

journal_title：Artificial organs

authors： Chandy T,Sharma CP

更新日期：1988-04-01 00:00:00

abstract：:Patients with end-stage renal failure and peripheral vascular disease pose a difficult management problem in establishing long-term angioaccess for hemodialysis. In 4 patients with access problems, we created axillary artery to contralateral axillary vein Goretex grafts. The grafts were cannulated regularly for period...

journal_title：Artificial organs

authors： Ono K,Muto Y,Yano K,Yukizane T

更新日期：1995-12-01 00:00:00

abstract：:One hundred and seventy-two patients at The Methodist Hospital in Houston, Texas, were placed on BioMedicus centrifugal ventricular support. One hundred thirty-nine patients were male and 33 were female with a mean age of 59.7 years. Reasons for support were postcardiotomy cardiac failure (129 patients), cardiac allog...

journal_title：Artificial organs

authors： Noon GP,Ball JW Jr,Papaconstantinou HT

更新日期：1995-07-01 00:00:00

abstract：:This article introduces a unique miniaturization process of a magnetically levitated axial flow blood pump from a functional prototype to a pump suitable for animal trials. Through COMSOL three-dimensional finite element analysis and experimental verification, the hybrid magnetic bearings of the pump have been miniatu...

journal_title：Artificial organs

authors： Cheng S,Olles MW,Olsen DB,Joyce LD,Day SW

更新日期：2010-10-01 00:00:00

abstract：:Bovine pericardium is a widely utilized biomaterial. Usually, after harvesting, it is advantageous that the pericardium be immersed in glycerol to improve its shelf life. This can induce some degree of toxicity in the material. The studies were performed in compliance with the rules of ISO 10993 and OECD 487, in the b...

journal_title：Artificial organs

authors： Rodas AC,Maizato MJ,Leirner AA,Pitombo RN,Polakiewicz B,Beppu MM,Higa OZ

更新日期：2008-04-01 00:00:00

abstract：:To date, single-needle (SN) hemodialysis (HD) requires a dialysis machine equipped with two blood pumps-one controlling arterial blood flow (Qb) and one controlling venous Qb. B. Braun has developed an innovative single-pump SN HD system. Therefore, usability is improved by reducing complexity. The aim of this study w...

journal_title：Artificial organs

authors： Bieser W,Welsch M,Jakob M,Meibaum J,Rodriguez DA,Wolff H,Marcelli D,Barth C

更新日期：2018-08-01 00:00:00

abstract：:The new Advanced ventricular assist device (Advanced VAD) has many features such as improving pulsatility and preventing regurgitant flow during pump stoppage. The purpose of this study was to evaluate the effects of design modifications of the Advanced VAD on these features in vitro. Bench testing of four versions of...

journal_title：Artificial organs

authors： Miyamoto T,Byram N,Karimov JH,Adams J,Dessoffy R,Kuban BD,Gao S,Horvath DJ,Fukamachi K

更新日期：2019-10-01 00:00:00

abstract：:Few instruments are currently available to test mitral valve function in an ex vivo state due to the technical difficulties involved. To investigate the native ex vivo mitral valve or prosthetic mitral valve with chordae, we developed a mitral valve adapter with an annulus suturing portion and 2 papillary muscle sutur...

journal_title：Artificial organs

authors： Katoh T,Ikeda N,Nishi K,Gohra H,Hamano K,Noda H,Fujimura Y,Esato K

更新日期：1999-10-01 00:00:00

abstract：:Albumin-coated Amberlite XAD-7 has been previously shown to be blood compatible in in vitro hemoperfusion experiments whith human blood. In this study, the preliminary results are reported on single hemoperfusions with albumin-coated XAD-7 resin in four patients with acute liver failure. The mean platelet count was 11...

journal_title：Artificial organs

authors： Hughes R,Ton HY,Langley P,Davies M,Hanid MA,Mellon P,Silk DB,Williams R

更新日期：1979-02-01 00:00:00

abstract：:Molecular biology has been moving swiftly toward clarifying the entire genome of organisms, including human. The human genome efforts that promote this transaction are characterized by the large-scale, high throughput production of data about the structure of the genome of the molecular level and its computer-assisted...

journal_title：Artificial organs

authors： Matsubara K

更新日期：1996-08-01 00:00:00

abstract：:The rotary blood pump will be an implantable left ventricular assist device (LVAD) in the near future. However, the best control method and the interrelationship between the rotary blood pump and native heart functions are unclear. An estimation was made of the native heart cardiac output from the change of an LVAD's ...

journal_title：Artificial organs

authors： Nakata K,Ohashi Y,Tayama E,Ohtsuka G,Takami Y,Mueller J,Glueck J,Nosé Y

更新日期：1998-05-01 00:00:00

abstract：:The E4T is a totally implantable total artificial heart (TAH) resulting from many years of research work at the Cleveland Clinic Foundation (CCF) and Nimbus, Inc. It consists of four implanted subsystems: the pumping unit, the variable volume device, the transcutaneous transformer, and the internal battery. The pumpin...

journal_title：Artificial organs

authors： Smith WA,Hete BF,Kiraly RJ,Fujimoto LK,Jacobs GB,Ishikawa M,Butler K,Nosé Y

更新日期：1988-10-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) is required in some lung transplantation (LTx) operations. However, it increases risks of bleeding and early graft dysfunction. We report our experiences of replacing CPB with heparin-bound extracorporeal membrane oxygenation (ECMO) in LTx operations. If extracorporeal circulation was anti...

journal_title：Artificial organs

authors： Ko WJ,Chen YS,Lee YC

更新日期：2001-08-01 00:00:00

abstract：:Malnutrition is a common feature seen in chronic dialysis patients, and the survival rate of obese patients receiving such treatment is higher than that of lean patients. Irrespective of obesity or diabetes, dialysis patients commonly have insulin resistance, and the leading cause of death is cardiovascular (CV) disea...

journal_title：Artificial organs

authors： Tanaka S,Yano S,Sheikh AM,Nagai A,Sugimoto T

更新日期：2014-07-01 00:00:00