The impact of polyethylene glycol conjugation on bovine hemoglobin's circulatory half-life and renal effects in a rabbit top-loaded transfusion model.

abstract：:Cyclosporine (CyA) has an immunosuppressive effect that might suggest a therapeutic role in idiopathic glomerular conditions. We focused on the optimization of CyA treatment control in patients with idiopathic nephrotic syndrome by using trough-level CyA measurements (C0) and the 2-h postdose levels (C2). Twenty-two p...

journal_title：Artificial organs

authors： Griveas I,Visvardis G,Papadopoulou D,Nakopolou L,Karanikas E,Gogos K,Stavianoudakis G

更新日期：2010-03-01 00:00:00

abstract：:The use of recombinant human erythropoietin (rHuEpo) has revolutionized anemia management of early and late stages of chronic kidney disease. Darbopoietin is also now available for the treatment of anemia of chronic kidney disease. In addition, rHuEpo has been used for the treatment of anemia observed in critical illn...

journal_title：Artificial organs

authors： Liangos O,Pereira BJ,Jaber BL

更新日期：2003-09-01 00:00:00

abstract：:Cardiovascular disorders are the leading causes of mortality and morbidity in the developed world. Cell-based modalities have received considerable scientific attention over the last decade for their potential use in this clinical arena. This review was intended as a brief overview on the subject of therapeutic potent...

journal_title：Artificial organs

authors： Akar AR,Durdu S,Corapcioglu T,Ozyurda U

更新日期：2006-04-01 00:00:00

abstract：:Changes in plasma sodium (Na) concentration during hemodialysis were predicted by changes in Na concentration of the dialysate at equilibrium with the plasma, according to the formula C't = CD - (CD - C'0) [(V0 - QFt)/V0]A/QF, where C'0 and C't are the Na concentration of the dialysate at equilibrium with the plasma a...

journal_title：Artificial organs

authors： Man NK,Petitclerc T,Tien NQ,Jehenne G,Funck-Brentano JL

更新日期：1985-05-01 00:00:00

abstract：:The optimal anticoagulation regimen for hemodialysis (HD) in patients with heparin-induced thrombocytopenia (HIT) has not been defined. Hemodiafiltration (HDF) adds a large convective component to HD, thereby changing the pharmacokinetics of most anticoagulants. Data on coagulation regimens for HDF are scant. We there...

journal_title：Artificial organs

authors： Mahieu E,Claes K,Jacquemin M,Evenepoel P,Op De Beek K,Bogaert AM,Kuypers D,Verhamme P,Meijers B

更新日期：2013-05-01 00:00:00

abstract：:In this proof of principle study, we investigated the effectiveness and safety of hemodynamic support with the Intra-Ventricular Membrane Pump (IVMP). The IVMP was implanted into the apex of the left ventricle. Hemodynamic assessment was performed in six ex vivo beating porcine hearts (PhysioHeart platform). The cardi...

journal_title：Artificial organs

authors： van Dort DIM,Thannhauser J,Gommans FDH,Ten Cate TJ,Duncker DJ,Suryapranata H,Morshuis WJ,Geuzebroek GSC

更新日期：2020-12-01 00:00:00

abstract：:Upon introducing off-pump coronary artery bypass grafting (CABG), the indications for CABG were expanded to include patients who previously had no operative indications. For accurate anastomosis, various devices and methods have been developed. Bradycardia is easily induced by drug administration. However, this method...

journal_title：Artificial organs

authors： Kuniyoshi Y,Koja K,Miyagi K,Shimoji M,Uezu T,Arakaki K,Yamashiro S,Mabuni K,Senaha S

更新日期：2002-10-01 00:00:00

abstract：:To avoid using sensors with low biocompatibility and low durability in implantable total artificial heart (TAH) systems, the authors previously proposed a new method for estimating instantaneous values of flow rate and pressure head on the basis of voltage, current, and rotational speed in a motor driven centrifugal p...

journal_title：Artificial organs

authors： Tanaka A,Yoshizawa M,Abe K,Takeda H,Yambe T,Nitta S

更新日期：2003-01-01 00:00:00

abstract：:A computational fluid dynamic model to assess the impact of flow-diverter device on intra-aneurysmal flow in complex aortic aneurysm from the viewpoint of hemodynamics is presented. The aim of this study is to investigate the hemodynamic effects of an endovascular flow-diverter technique using multiple overlapping unc...

journal_title：Artificial organs

authors： Yeow SL,Leo HL

更新日期：2018-02-01 00:00:00

abstract：:Chitosan posttreatment has been shown to be effective in prevention of calcification of the glutaraldehyde treated bovine pericardium when implanted subdermally in rats for 12 weeks. The efficacy of chitosan posttreatment in complete calcium mitigation of the glutaraldehyde treated porcine aortic valves implanted in t...

journal_title：Artificial organs

authors： Chanda J,Kuribayashi R,Abe T,Sekine S,Shibata Y,Yamagishi I

更新日期：1997-05-01 00:00:00

abstract：:Creating an interatrial shunt to achieve left-right flow balance and modification of the blood chambers to improve the basic performance of the device were performed in developing an eccentric roller type total artificial heart (ERTAH). Smaller blood chambers reduce friction loss and increase durability and energy eff...

journal_title：Artificial organs

authors： Wada H,Fukunaga S,Watari M,Imai K,Sakai H,Shibamura H,Sueda T,Matsuura Y

更新日期：2000-08-01 00:00:00

abstract：:The objective of our study was to investigate chondrogenesis potential of human adipose-derived mesenchymal stromal cells (MSCs), using as a positive control a human source of cartilage-derived progenitor cells (PCs). This source of PCs was recently described by our group and dwells on the surface of nasoseptal cartil...

journal_title：Artificial organs

authors： Baptista LS,Silva KR,Pedrosa CS,Amaral RJ,Belizário JV,Borojevic R,Granjeiro JM

更新日期：2013-12-01 00:00:00

abstract：:Individualized short hemodialysis treatment schedules, approximately three 3-h treatments per week, were introduced in a nephrology unit in 1976. In May 1985, 259 patients had been treated, which corresponds to approximately 60 new patients per million inhabitants per year. Ages at start of therapy ranged between 17 a...

journal_title：Artificial organs

authors： Wauters JP,Bercini-Pansiot S,Gilliard N,Stauffer JC

更新日期：1986-06-01 00:00:00

abstract：:Robotic surgery for intracardiac pathologies in children is relatively uncommon. This study presents our initial experience with robotic-assisted cardiac surgery in children. We also present the feasibility and safety of robotic surgery in children. From May 2013 to June 2018, 30 children underwent totally endoscopic ...

journal_title：Artificial organs

authors： Onan B,Aydin U,Kadirogullari E,Onan IS,Sen O

更新日期：2019-04-01 00:00:00

abstract：:The vibrating flow pump (VFP) can generate high frequency oscillated blood flow. Because of the high frequency driving with short stroke volume, the pump system can be small. The disposable type VFP (D-VFP) was developed for use for extracorporeal circulation. The electromagnetic actuator was detached from the vibrati...

journal_title：Artificial organs

authors： Kobayashi S,Nitta S,Yambe T,Sonobe T,Naganuma S,Hashimoto H

更新日期：1997-07-01 00:00:00

abstract：:The objective of this study is to compare the myocardium protective effect of Bretschneider's histidine-tryptophan-ketoglutarate (HTK) solution versus Modified St. Thomas' (STH) solution in pediatric cardiac surgery of Tetralogy of Fallot (TOF). Seventy-seven pediatric patients of TOF who received the total surgical r...

journal_title：Artificial organs

authors： Wang ZH,An Y,Du MC,Qin TJ,Liu YB,Xu HZ,Yang LQ

更新日期：2017-05-01 00:00:00

abstract：:The flow of blood as a viscous, Newtonian, incompressible liquid in an expanding spherical cavity with a ball-type inlet valve was examined. This type of flow can serve as a model of the phase of ventricular diastole in a sac-type artificial heart. The critical values of Reynolds numbers at which flow interruption beh...

journal_title：Artificial organs

authors： Starobin IM,Zaĭko VM

更新日期：1983-02-01 00:00:00

abstract：:This study aimed to clarify the role of peritoneal T-lymphocytes in peritoneal immune defense mechanisms. This study was designed to examine the changes in T-cell subpopulations during peritonitis in patients treated with continuous ambulatory peritoneal dialysis (CAPD). Our observations were correlated to responses t...

journal_title：Artificial organs

authors： Griveas I,Fleva A,Karanikas E,Gogos K,Sakellariou G

更新日期：2009-12-01 00:00:00

abstract：:Ten dialysis patients were followed in a prospective study to determine the neurotoxicity of metabolites in the middle molecule (MM) molecular weight (mol wt) range of 500-200 daltons/molecule. In the absence of readily available direct serum measurements of MM concentrations, a theoretically calculated dialysis index...

journal_title：Artificial organs

authors： Milutinovic J,Babb AL,Eschbach JW,Follette WC,Graefe U,Strand MJ,Scribner BH

更新日期：1978-02-01 00:00:00

abstract：:Recent studies show that oxytocin has various effects on cellular behaviors. Oxytocin is reported to stimulate cardiomyogenesis of embryonic stem cells and endothelial cell proliferation. Mesenchymal stem cells (MSCs) are widely used for cardiac repair, and we elucidated the effect of oxytocin on umbilical cord derive...

journal_title：Artificial organs

authors： Kim YS,Kwon JS,Hong MH,Kim J,Song CH,Jeong MH,Cho JG,Park JC,Kang JC,Ahn Y

更新日期：2010-06-01 00:00:00

abstract：:Multiple observational studies along with a limited number of randomized clinical trials suggest that intensive hemodialysis (IHD) not only improves outcomes for uremic patients undergoing chronic dialysis but does so with a more favorable cost/benefit ratio compared with conventional hemodialysis. As a result of this...

journal_title：Artificial organs

authors： Naso A,Scaparrotta G,Naso E,Calò LA

更新日期：2015-09-01 00:00:00

abstract：:The aim of the present study was to compare the effects of ProTaper Gold, WaveOne Gold, ProTaper Universal, and WaveOne instruments on the amount of apically extruded debris. Eighty mandibular premolar teeth with straight root canals were selected and assigned to four groups (n = 20). The root canals were instrumented...

journal_title：Artificial organs

authors： Karataş E,Ersoy İ,Gündüz HA,Uygun AD,Kol E,Çakıcı F

更新日期：2016-08-01 00:00:00

abstract：:Turbulent blood flow in medical devices contributes to blood trauma, yet the exact mechanism(s) have not been fully elucidated. Local turbulent stresses, viscous stresses, and the rate of dissipation of the turbulent kinetic energy have been proffered as hypotheses to describe and predict blood damage. In this work, s...

journal_title：Artificial organs

authors： Ozturk M,O'Rear EA,Papavassiliou DV

更新日期：2015-12-01 00:00:00

abstract：:The in vitro development of a vascular stroma might be a solution for the engineering of vascularized tissues, however, in vitro stability of capillary-like structures is limited. In order to test the influence on maintenance of capillary-like structures, human growth hormone (hGH) was added in concentrations of 0.5, ...

journal_title：Artificial organs

authors： Frerich B,Kurtz-Hoffmann J,Lindemann N

更新日期：2005-04-01 00:00:00

abstract：:Giant cerebral aneurysms may be untreatable by conventional neurosurgical techniques. Early attempts to use circulatory assistance and deep hypothermia were abandoned due to hemorrhagic complications. More recently, interest in circulatory support for complex neurosurgical procedures has been renewed. A consecutive se...

journal_title：Artificial organs

authors： Mesana T,Collart F,Caus T,Pomane C,Graziani N,Bruder N,Dufour H,Grisoli F,Montiès JR

更新日期：2000-06-01 00:00:00

abstract：:This article presents results from the field calculation in a model of biological tissue taking into account the electroporation process. The electroporation model used in this study was proposed and experimentally verified by Glaser et al. for planar membranes. The numerical method for field calculation is based on a...

journal_title：Artificial organs

authors： Ramos A

更新日期：2005-06-01 00:00:00

abstract：:Mycotic aneurysm of the superior mesenteric artery (SMA) is one of the complications associated with infective endocarditis. However, there are no previous case reports in the literature describing mycotic SMA aneurysm after left ventricular assist device (LVAD) implantation. We describe the case of a 31-year-old male...

journal_title：Artificial organs

authors： Motomura T,Bruckner B,Leon-Becerril J,Anaya-Ayala JE,de Rienzo-Madero B,Bismuth J,Bunge R,Irwin S,Loebe M

更新日期：2011-07-01 00:00:00

abstract：:Centrifugal blood pumps are considered to be generally superior to the traditionally used roller pumps in cardiopulmonary bypass. In our institute a new lightweight centrifugal sealless blood pump with a unique spherical thrust bearing and with a magnetic coupling was developed, the HiFlow. The small design makes the ...

journal_title：Artificial organs

authors： Göbel C,Eilers R,Reul H,Schwindke P,Jörger M,Rau G

更新日期：1997-07-01 00:00:00

abstract：:Bone marrow mesenchymal stem cells (MSCs) have demonstrated their pluripotency to differentiate into different cell lineages and may be an alternative cell source for vascular tissue engineering. The objective of this study is to create small diameter vessels by seeding and culture of genetically modified MSCs onto a ...

journal_title：Artificial organs

authors： Zhang J,Qi H,Wang H,Hu P,Ou L,Guo S,Li J,Che Y,Yu Y,Kong D

更新日期：2006-12-01 00:00:00

abstract：:A magnetically levitated (maglev) centrifugal blood pump (CBP), intended for use as a ventricular assist device, needs to be highly durable and reliable for long-term use without any mechanical failure. Furthermore, maglev CBPs should be small enough to be implanted into patients of various size and weight. We have de...

journal_title：Artificial organs

authors： Asama J,Shinshi T,Hoshi H,Takatani S,Shimokohbe A

更新日期：2006-03-01 00:00:00