Down-regulation of TNF-alpha by small interfering RNA inhibits particle-induced inflammation in vitro.

abstract：:The multi-output adaptive controller of a left ventricular assist device (LVAD) was studied by computer simulation. The controller regulated two outputs--mean aortic pressure (mAoP) and mean atrial pressure (mLAP)--by regulating vacuum pressure (input). The autoregressive models were used to describe the circulatory s...

journal_title：Artificial organs

authors： Shimooka T,Mitamura Y,Yuhta T

更新日期：1991-04-01 00:00:00

abstract：:In this pilot study, we assessed the feasibility of using positron emission tomography (PET) imaging for in vivo measurement of skeletal muscle ventricle (SMV) tissue blood flow. In 4 dogs, with SMVs prepared from their latissimus dorsi muscle, we quantified SMV tissue blood flow by PET and related it to the tissue fl...

journal_title：Artificial organs

authors： Singh TP,Greer K,Muzik O,Hammond RL,Stephenson LW,Di Carli MF

更新日期：2001-04-01 00:00:00

abstract：:In chronic cardiomyopathy, mechanical circulatory support (MCS) plays an increasingly important role for children as the shortage of suitable donor hearts increases waiting time on the transplant list. We report our experience with the paracorporal Berlin Heart EXCOR System (Berlin Heart AG, Berlin, Germany) used as a...

journal_title：Artificial organs

authors： Schweiger M,Schrempf J,Sereinigg M,Prenner G,Tscheliessnigg KH,Wasler A,Krumnikel J,Gamillschegg A,Knez I

更新日期：2013-08-01 00:00:00

abstract：:Many types of rotary blood pumps and pump control methods have recently been developed with the goal of clinical use. From experiments, we know that pump flow spontaneously increases during exercise without changing pump control parameters. The purpose of this study was to determine the hemodynamics associated with th...

journal_title：Artificial organs

authors： Akimoto T,Yamazaki K,Litwak P,Litwak KN,Tagusari O,Mori T,Antaki JF,Kameneva MV,Watach MJ,Umezu M,Tomioka J,Kormos RL,Koyanagi H,Griffith BP

更新日期：1999-08-01 00:00:00

abstract：:Recent progress in the development of implantable rotary blood pumps realized long-term mechanical circulatory support (MCS) for bridge to transplant, bridge to recovery, or a destination therapy. Meanwhile, a short-term MCS system is becoming necessary for bridge to decision. We developed a novel inflow cannula for t...

journal_title：Artificial organs

authors： Sumikura H,Toda K,Takewa Y,Tsukiya T,Ohnuma K,Sasagawa M,Watanabe F,Ugawa J,Taenaka Y,Tatsumi E

更新日期：2011-08-01 00:00:00

abstract：:Using urea and inulin as markers, we have developed a simple method to calculate intracellular and extracellular fluid volume in patients before and after hemofiltration therapy. During conventional hemofiltration using substitution fluid with a Na+ concentration of 140 mEq/L, a decrease in extracellular fluid volume ...

journal_title：Artificial organs

authors： Kimura G,Satani M,Kojima S,Kuroda K,Itoh K,Ikeda M

更新日期：1982-02-01 00:00:00

abstract：:Bubble blood oxygenators equipped with baffles of various types in the oxygenating column were studied. The rate of hemolysis, the volumetric coefficient for oxygen absorption into blood, and the fractional gas holdup were found to be affected mainly by the superficial gas velocity. When compared with the conventional...

journal_title：Artificial organs

authors： Ohshima N,Yoshido F

更新日期：1979-05-01 00:00:00

abstract：:Centrifugal pumps have been used widely as the main pump in open heart surgery to reduce damage to blood elements and to reduce the activation of the coagulation system. The purpose of this study was the evaluation and comparison of the effects of two types of centrifugal pumps and of one type of roller pump on blood ...

journal_title：Artificial organs

authors： Yoshikai M,Hamada M,Takarabe K,Okazaki Y,Yoshika M

更新日期：1996-05-01 00:00:00

abstract：:A totally implantable centrifugal artificial heart has been developed in which a pivot bearing supported centrifugal pump is used as a blood pump. The following have been adopted as blood contacting materials in our pump: titanium alloy (Ti-6A1-4V) for the housing and impeller, alumina ceramic (Al2O3) for the male piv...

journal_title：Artificial organs

authors： Takami Y,Yamane S,Makinouchi K,Niimi Y,Sueoka A,Nosé Y

更新日期：1998-09-01 00:00:00

abstract：:Technological innovations in pediatric extracorporeal life support circuits can reduce system-related complications and may improve patients' outcome. The Deltastream DP3 (Medos Medizintechnik AG, Stolberg, Germany) is a novel rotational pump with a diagonally streamed impeller that can be used over a broad range of f...

journal_title：Artificial organs

authors： Stiller B,Houmes RJ,Rüffer A,Kumpf M,Müller A,Kipfmüller F,Köditz H,Herber Jonat S,Schmoor C,Benk C,Tibboel D,Fleck T

更新日期：2018-04-01 00:00:00

abstract：:The objective of this study was to compare the hemodynamic performances and gaseous microemboli (GME) handling ability of two pediatric oxygenators in a simulated pediatric cardiopulmonary bypass (CPB) model and the importance of adding an arterial filter in the circuit. The circuit consisted of a Braile Infant oxygen...

journal_title：Artificial organs

authors： Wang S,Caneo LF,Jatene MB,Jatene FB,Cestari IA,Kunselman AR,Ündar A

更新日期：2017-09-01 00:00:00

abstract：:Neurologic complications during neonatal extracorporeal life support (ECLS) are associated with significant morbidity and mortality. Gaseous microemboli (GME) in the ECLS circuit may be a possible cause. Advances in neonatal circuitry may improve hemodynamic performance and GME handling leading to reduction in patient...

journal_title：Artificial organs

authors： Glass K,Trivedi P,Wang S,Woitas K,Kunselman AR,Ündar A

更新日期：2017-04-01 00:00:00

abstract：:The purpose of this study was to investigate whether an artificial matrix can help neonatal cardiomyocytes restore an injured heart in a rat model of myocardial infarction (MI). The left coronary arteries of female Sprague Dawley (SD) rats were ligated to create MI models. Ventricular cardiomyocytes from 1- to 3-day-o...

journal_title：Artificial organs

authors： Zhang P,Zhang H,Wang H,Wei Y,Hu S

更新日期：2006-02-01 00:00:00

abstract：:Cardiovascular disorders are the leading causes of mortality and morbidity in the developed world. Cell-based modalities have received considerable scientific attention over the last decade for their potential use in this clinical arena. This review was intended as a brief overview on the subject of therapeutic potent...

journal_title：Artificial organs

authors： Akar AR,Durdu S,Corapcioglu T,Ozyurda U

更新日期：2006-04-01 00:00:00

abstract：:The accurate representation of rotary blood pumps in a numerical environment is important for meaningful investigation of pump-cardiovascular system interactions. Although numerous models for ventricular assist devices (VADs) have been developed, modeling methods for rotary total artificial hearts (rTAHs) are still re...

journal_title：Artificial organs

authors： Nestler F,Bradley AP,Wilson SJ,Timms DL

更新日期：2014-03-01 00:00:00

abstract：:The use of extracorporeal membrane oxygenator instead of standard cardiopulmonary bypass during lung transplantation is debatable. Moreover, recently, the concept of prolonged postoperative extracorporeal membrane oxygenator (ECMO) support has been introduced in many transplant centers to prevent primary graft dysfunc...

journal_title：Artificial organs

authors： Dell'Amore A,Campisi A,Congiu S,Mazzarra S,Pastore S,Dolci G,Baiocchi M,Frascaroli G

更新日期：2020-06-01 00:00:00

abstract：:The use of recombinant human erythropoietin (rHuEpo) has revolutionized anemia management of early and late stages of chronic kidney disease. Darbopoietin is also now available for the treatment of anemia of chronic kidney disease. In addition, rHuEpo has been used for the treatment of anemia observed in critical illn...

journal_title：Artificial organs

authors： Liangos O,Pereira BJ,Jaber BL

更新日期：2003-09-01 00:00:00

abstract：:Hemodynamic control of left ventricular assist devices (LVADs) is generally a complicated problem due to diverse operating environments and the variability of the patients: both the changes in the circulatory and metabolic parameters as well as disturbances that require adjustment to the operating point. This challeng...

journal_title：Artificial organs

authors： Choi S,Boston JR,Antaki JF

更新日期：2007-02-01 00:00:00

abstract：:Most bioartificial liver support systems are based on hollow fiber capillaries within modified dialysis cartridges or more sophisticated bioreactor constructions. Due to their design microscopic follow-up of reorganization and growth of tissue between the hollow fibers is not possible. The SlideReactor is a simple hol...

journal_title：Artificial organs

authors： Sauer IM,Schwartlander R,Schmid J,Efimova E,Vondran FW,Kehr D,Pless G,Spinelli A,Brandenburg B,Hildt E,Neuhaus P

更新日期：2005-03-01 00:00:00

abstract：:Heparin remains the predominant anticoagulant during extracorporeal membrane oxygenation (ECMO). Heparin acts by potentiating the anticoagulant effect of antithrombin (ATIII). Acquired ATIII deficiency, common in pediatric patients requiring ECMO, may result in ineffective anticoagulation with heparin. ATIII replaceme...

journal_title：Artificial organs

authors： Niebler RA,Christensen M,Berens R,Wellner H,Mikhailov T,Tweddell JS

更新日期：2011-11-01 00:00:00

abstract：:Thirty-five patients undergoing open-heart surgery are reported. Cardiac index, mean arterial pressure, oxygen consumption, lactate, pyruvate, and lactate excess in the blood were measured. An inverse correlation of arterial pressure with oxygen consumption and lactate excess was found during perfusion. Comparison of ...

journal_title：Artificial organs

authors： Osipov VP,Khodas MJ,Dementjeva II,Pjatnitskaja GKh

更新日期：1982-08-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) requirement in infants presents a unique challenge because of the large prime volume-to-blood volume ratio. Packed red blood cells (PRBCs) tend to deteriorate with long-term storage owing to their unphysiological composition and osmolality. Given that blood priming is inevitable in neonate...

journal_title：Artificial organs

authors： Gholampour Dehaki M,Niknam S,Bakhshandeh H,Azarfarin R

更新日期：2020-03-01 00:00:00

abstract：:Clinically, the percutaneous transcatheter aortic valve (TAV) has been reported to be deformed in a noncircular configuration after its implant. The deformation is universal and various, and it leads to serious leakage and durability problems. Even in the same deformation, the leaflets made in different tissue thickne...

journal_title：Artificial organs

authors： Feng W,Yang X,Liu Y,Fan Y

更新日期：2017-08-01 00:00:00

abstract：:The Genius is a convenient single-pass batch hemodialysis system. Dialysate is heated during the preparation phase. Once the container is filled at one of the three available starting temperatures, dialysate cools spontaneously. As dialysate temperature plays an important role in hemodynamic stability, knowledge of th...

journal_title：Artificial organs

authors： Dhondt A,Eloot S,Verbeke F,Vanholder R

更新日期：2010-12-01 00:00:00

abstract：:The rapid acceleration of technology development is outpacing our ability to assess it objectively and competently. Our challenge is to develop new assessment methods that take into account the fast moving nature of technology development while still protecting the patients' and the public interest. ...

journal_title：Artificial organs

authors： Abele JE

更新日期：1998-01-01 00:00:00

abstract：:Magnevad II is an improved version of Magnevad I and both are fourth-generation axial flow left ventricular assist devices. A major simplification has been implemented and tested. Magnevad I used a magnetically suspended rotor requiring active axial control. Magnevad II is completely passive but otherwise similar. A s...

journal_title：Artificial organs

authors： Goldowsky M,Lafaro R,Reed G

更新日期：2005-10-01 00:00:00

abstract：:Central extracorporeal life support (ECLS) is an effective treatment method of cardiogenic shock patients with or without lung failure. However, complications like infection and bleeding are common. The classical implantation approach requires full sternotomy, mobilization of the heart, with the well-known risks of bl...

journal_title：Artificial organs

authors： Weymann A,Sabashnikov A,Patil NP,Mohite PN,Zych B,Garcia Saez D,Popov AF,Simon AR

更新日期：2015-02-01 00:00:00

abstract：:The characteristic depressed hemodynamic state and gradually declining circulatory function in Fontan patients necessitates alternative postoperative management strategies incorporating a system level approach. In this study, the single-ventricle Fontan circulation is modeled by constructing a practical in vitro bench...

journal_title：Artificial organs

authors： Dur O,Lara M,Arnold D,Vandenberghe S,Keller BB,DeGroff C,Pekkan K

更新日期：2009-11-01 00:00:00

abstract：:Features of the human spinal cord motor control are described using two spinal cord injury models: (i) the spinal cord completely separated from brain motor structures by accidental injury; (ii) the spinal cord receiving reduced and altered supraspinal input due to an incomplete lesion. Systematic studies using surfac...

journal_title：Artificial organs

authors： Dimitrijevic MR,Persy I,Forstner C,Kern H,Dimitrijevic MM

更新日期：2005-03-01 00:00:00

abstract：:The injurious effects of reactive oxygen species on venous tissues and the potential protective role played by green tea polyphenol (GTPP) on human saphenous veins were investigated. Oxidative stress was induced exogenously in the vein segments, either by adding 0.8 or 1.6 M of H2O2, or by using 80 or 160 U/L of xanth...

journal_title：Artificial organs

authors： Han DW,Suh H,Park YH,Cho BK,Hyon SH,Park JC

更新日期：2003-12-01 00:00:00