Anemia in acute renal failure: role for erythropoiesis-stimulating proteins?

Abstract:

:The use of recombinant human erythropoietin (rHuEpo) has revolutionized anemia management of early and late stages of chronic kidney disease. Darbopoietin is also now available for the treatment of anemia of chronic kidney disease. In addition, rHuEpo has been used for the treatment of anemia observed in critical illness. Unfortunately, the existing clinical studies of anemia in critically ill patients do not distinguish between those with and without acute renal failure (ARF). This review summarizes the existing experimental and clinical studies supporting the use of rHuEpo in ARF due to ischemic/nephrotoxic injury and conclusions are drawn on the rationale for further research into the use of this drug in ARF.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Liangos O,Pereira BJ,Jaber BL

doi

10.1046/j.1525-1594.2003.07287.x

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

786-91

issue

9

eissn

0160-564X

issn

1525-1594

pii

7287

journal_volume

27

pub_type

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